Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1263

Experiment: 7H9 with Meropenem 9.6 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Meropenem 9.6 ug/mL
1,409,433	-				-0.3
1,409,433	-				+0.1
1,409,546	-		Rv1261c	0.14	+3.4
1,409,590	+		Rv1261c	0.24	+0.5
1,409,686	+		Rv1261c	0.45	-0.4
1,409,734	+		Rv1261c	0.56	-0.3
1,409,755	+		Rv1261c	0.60	+0.3
1,410,071	-		Rv1262c	0.31	-0.6
1,410,318	-		Rv1262c	0.87	+0.9
1,410,420	-				-1.5
1,410,707	+		Rv1263	0.20	-0.7
1,410,708	-		Rv1263	0.20	-0.1
1,411,278	+		Rv1263	0.61	-0.5
1,411,334	+		Rv1263	0.65	-0.2
1,411,335	-		Rv1263	0.65	-0.9
1,411,343	+		Rv1263	0.66	-0.0
1,411,344	-		Rv1263	0.66	+0.3
1,411,437	+		Rv1263	0.72	-0.2
1,411,533	+		Rv1263	0.79	-0.3
1,411,533	+		Rv1263	0.79	+0.2
1,411,533	+		Rv1263	0.79	+0.8
1,411,634	+		Rv1263	0.87	+1.4
1,411,635	-		Rv1263	0.87	+0.2
1,412,089	+		Rv1264	0.16	+2.1
1,412,089	+		Rv1264	0.16	-0.9
1,412,089	+		Rv1264	0.16	-1.5
1,412,090	-		Rv1264	0.16	-1.3
1,412,090	-		Rv1264	0.16	-0.5
1,412,090	-		Rv1264	0.16	+0.2
1,412,090	-		Rv1264	0.16	+0.6
1,412,090	-		Rv1264	0.16	-1.0
1,412,094	-		Rv1264	0.17	-1.1
1,412,119	+		Rv1264	0.19	-0.0
1,412,119	+		Rv1264	0.19	+0.1
1,412,120	-		Rv1264	0.19	-0.4
1,412,673	+		Rv1264	0.65	+0.6
1,412,674	-		Rv1264	0.65	+1.8