Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0973c and Rv0974c are separated by 5 nucleotides Rv0974c and Rv0975c are separated by 2 nucleotides
Rv0973c: Rv0973c - Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrier protein (BCCP), at 1,083,747 to 1,085,750
Rv0973c
Rv0974c: Rv0974c - Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD2, at 1,085,756 to 1,087,345
Rv0974c
Rv0975c: Rv0975c - Probable acyl-CoA dehydrogenase FadE13, at 1,087,348 to 1,088,496
Rv0975c
Position (kb)
1085
1086
1087
1088 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1084.912 kb on + strand, within Rv0973c at 1086.102 kb on + strand, within Rv0974c at 1086.214 kb on - strand, within Rv0974c at 1087.466 kb on + strand, within Rv0975c at 1087.467 kb on - strand, within Rv0975c at 1087.604 kb on + strand, within Rv0975c at 1088.027 kb on + strand, within Rv0975c at 1088.027 kb on + strand, within Rv0975c at 1088.028 kb on - strand, within Rv0975c at 1088.083 kb on + strand, within Rv0975c at 1088.084 kb on - strand, within Rv0975c at 1088.240 kb on + strand, within Rv0975c at 1088.241 kb on - strand, within Rv0975c at 1088.241 kb on - strand, within Rv0975c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 1,084,912 + Rv0973c 0.58 +0.1 1,086,102 + Rv0974c 0.22 -0.4 1,086,214 - Rv0974c 0.29 +1.8 1,087,466 + Rv0975c 0.10 -2.2 1,087,467 - Rv0975c 0.10 -0.4 1,087,604 + Rv0975c 0.22 -0.0 1,088,027 + Rv0975c 0.59 +0.9 1,088,027 + Rv0975c 0.59 +2.4 1,088,028 - Rv0975c 0.59 -0.7 1,088,083 + Rv0975c 0.64 -0.5 1,088,084 - Rv0975c 0.64 +0.1 1,088,240 + Rv0975c 0.78 -0.0 1,088,241 - Rv0975c 0.78 -0.1 1,088,241 - Rv0975c 0.78 -0.1
Or see this region's nucleotide sequence