Experiment: 7H9 with Meropenem 9.6 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0818 and Rv0819 overlap by 4 nucleotides Rv0819 and Rv0820 are separated by 42 nucleotides Rv0820 and Rv0821c are separated by 55 nucleotides Rv0821c and Rv0822c are separated by 57 nucleotides
Rv0818: Rv0818 - Transcriptional regulatory protein, at 910,972 to 911,739
Rv0818
Rv0819: Rv0819 - GCN5-related N-acetyltransferase, MshD, at 911,736 to 912,683
Rv0819
Rv0820: Rv0820 - Probable phosphate-transport ATP-binding protein ABC transporter PhoT, at 912,726 to 913,502
Rv0820
Rv0821c: Rv0821c - Probable phosphate-transport system transcriptional regulatory protein PhoY2, at 913,558 to 914,199
Rv0821c
Rv0822c: Rv0822c - Conserved protein, at 914,257 to 916,311
Rv0822c
Position (kb)
912
913
914 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 912.161 kb on + strand, within Rv0819 at 912.205 kb on - strand, within Rv0819 at 912.442 kb on - strand, within Rv0819 at 912.442 kb on - strand, within Rv0819 at 912.579 kb on + strand, within Rv0819 at 912.580 kb on - strand, within Rv0819 at 912.580 kb on - strand, within Rv0819 at 912.640 kb on - strand at 912.678 kb on - strand at 912.723 kb on + strand at 912.723 kb on + strand at 912.724 kb on - strand at 912.763 kb on - strand at 912.765 kb on + strand at 912.766 kb on - strand at 912.942 kb on - strand, within Rv0820 at 912.942 kb on - strand, within Rv0820 at 912.945 kb on + strand, within Rv0820 at 912.945 kb on + strand, within Rv0820 at 912.945 kb on + strand, within Rv0820 at 913.317 kb on + strand, within Rv0820 at 913.317 kb on + strand, within Rv0820 at 913.318 kb on - strand, within Rv0820 at 913.340 kb on + strand, within Rv0820 at 913.341 kb on - strand, within Rv0820 at 913.420 kb on + strand, within Rv0820 at 913.421 kb on - strand, within Rv0820 at 913.500 kb on + strand at 913.631 kb on + strand, within Rv0821c at 913.632 kb on - strand, within Rv0821c at 913.632 kb on - strand, within Rv0821c at 913.842 kb on - strand, within Rv0821c at 914.135 kb on - strand at 914.186 kb on + strand at 914.186 kb on + strand at 914.205 kb on - strand at 914.211 kb on + strand at 914.212 kb on - strand at 914.338 kb on + strand at 914.339 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Meropenem 9.6 ug/mL remove 912,161 + Rv0819 0.45 +0.8 912,205 - Rv0819 0.49 -2.7 912,442 - Rv0819 0.74 -2.2 912,442 - Rv0819 0.74 -3.4 912,579 + Rv0819 0.89 -1.9 912,580 - Rv0819 0.89 -1.2 912,580 - Rv0819 0.89 -2.0 912,640 - -0.8 912,678 - -3.2 912,723 + -2.0 912,723 + -1.5 912,724 - -2.1 912,763 - -0.5 912,765 + -3.4 912,766 - -2.4 912,942 - Rv0820 0.28 -0.9 912,942 - Rv0820 0.28 -2.4 912,945 + Rv0820 0.28 -2.8 912,945 + Rv0820 0.28 -0.2 912,945 + Rv0820 0.28 +0.3 913,317 + Rv0820 0.76 -1.2 913,317 + Rv0820 0.76 -2.1 913,318 - Rv0820 0.76 -0.5 913,340 + Rv0820 0.79 -3.0 913,341 - Rv0820 0.79 -3.7 913,420 + Rv0820 0.89 -2.8 913,421 - Rv0820 0.89 -2.0 913,500 + +0.6 913,631 + Rv0821c 0.11 -1.5 913,632 - Rv0821c 0.12 +0.6 913,632 - Rv0821c 0.12 -1.2 913,842 - Rv0821c 0.44 -2.1 914,135 - -0.6 914,186 + -0.6 914,186 + +1.8 914,205 - -1.2 914,211 + -0.4 914,212 - -0.1 914,338 + +0.7 914,339 - -0.8
Or see this region's nucleotide sequence