Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3061c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3060c and Rv3061c are separated by 48 nucleotidesRv3061c and Rv3062 are separated by 156 nucleotides Rv3060c: Rv3060c - Probable transcriptional regulatory protein (probably GntR-family), at 3,421,741 to 3,423,213 Rv3060c Rv3061c: Rv3061c - Probable acyl-CoA dehydrogenase FadE22, at 3,423,262 to 3,425,427 Rv3061c Rv3062: Rv3062 - Probable ATP-dependent DNA ligase LigB (polydeoxyribonucleotide synthase [ATP]) (polynucleotide ligase [ATP]) (sealase) (DNA repair protein) (DNA joinase), at 3,425,584 to 3,427,107 Rv3062 Position (kb) 3423 3424 3425 3426Strain fitness (log2 ratio) -2 -1 0 1at 3422.267 kb on + strand, within Rv3060cat 3422.720 kb on - strand, within Rv3060cat 3422.847 kb on + strand, within Rv3060cat 3423.226 kb on + strandat 3423.267 kb on + strandat 3424.051 kb on + strand, within Rv3061cat 3424.491 kb on + strand, within Rv3061cat 3424.492 kb on - strand, within Rv3061cat 3424.541 kb on + strand, within Rv3061cat 3424.541 kb on + strand, within Rv3061cat 3424.541 kb on + strand, within Rv3061cat 3424.542 kb on - strand, within Rv3061cat 3424.542 kb on - strand, within Rv3061cat 3424.734 kb on - strand, within Rv3061cat 3425.053 kb on - strand, within Rv3061cat 3425.124 kb on + strand, within Rv3061cat 3425.231 kb on + strandat 3425.231 kb on + strandat 3425.781 kb on - strand, within Rv3062

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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3,422,267 + Rv3060c 0.36 -0.1
3,422,720 - Rv3060c 0.66 -0.2
3,422,847 + Rv3060c 0.75 -1.2
3,423,226 + +0.1
3,423,267 + -0.3
3,424,051 + Rv3061c 0.36 -0.2
3,424,491 + Rv3061c 0.57 -0.1
3,424,492 - Rv3061c 0.57 -0.8
3,424,541 + Rv3061c 0.59 -0.9
3,424,541 + Rv3061c 0.59 -0.2
3,424,541 + Rv3061c 0.59 +0.5
3,424,542 - Rv3061c 0.59 -0.2
3,424,542 - Rv3061c 0.59 +0.0
3,424,734 - Rv3061c 0.68 -2.1
3,425,053 - Rv3061c 0.83 +0.5
3,425,124 + Rv3061c 0.86 -1.1
3,425,231 + -0.5
3,425,231 + -0.2
3,425,781 - Rv3062 0.13 +1.4

Or see this region's nucleotide sequence