Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1616

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1615 and Rv1616 overlap by 11 nucleotidesRv1616 and Rv1617 are separated by 107 nucleotides Rv1615: Rv1615 - Probable membrane protein, at 1,815,253 to 1,815,693 Rv1615 Rv1616: Rv1616 - Conserved membrane protein, at 1,815,683 to 1,816,081 Rv1616 Rv1617: Rv1617 - Probable pyruvate kinase PykA, at 1,816,189 to 1,817,607 Rv1617 Position (kb) 1815 1816 1817Strain fitness (log2 ratio) -2 -1 0 1 2at 1814.707 kb on + strandat 1814.747 kb on - strandat 1814.756 kb on - strandat 1814.761 kb on - strandat 1814.850 kb on + strandat 1814.850 kb on + strandat 1814.850 kb on + strandat 1814.850 kb on + strandat 1814.851 kb on - strandat 1814.851 kb on - strandat 1814.861 kb on - strandat 1814.925 kb on - strandat 1815.409 kb on + strand, within Rv1615at 1815.409 kb on + strand, within Rv1615at 1815.409 kb on + strand, within Rv1615at 1815.409 kb on + strand, within Rv1615at 1815.539 kb on - strand, within Rv1615at 1815.549 kb on + strand, within Rv1615at 1815.792 kb on + strand, within Rv1616at 1815.795 kb on - strand, within Rv1616at 1815.808 kb on - strand, within Rv1616at 1815.873 kb on + strand, within Rv1616at 1816.059 kb on + strandat 1816.160 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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1,814,707 + +0.3
1,814,747 - +0.4
1,814,756 - +1.9
1,814,761 - -0.1
1,814,850 + -0.5
1,814,850 + -0.2
1,814,850 + +1.0
1,814,850 + -0.9
1,814,851 - -0.1
1,814,851 - -0.3
1,814,861 - -1.9
1,814,925 - +0.2
1,815,409 + Rv1615 0.35 -1.4
1,815,409 + Rv1615 0.35 -0.5
1,815,409 + Rv1615 0.35 -0.3
1,815,409 + Rv1615 0.35 -0.1
1,815,539 - Rv1615 0.65 +0.3
1,815,549 + Rv1615 0.67 +0.0
1,815,792 + Rv1616 0.27 -0.0
1,815,795 - Rv1616 0.28 -0.7
1,815,808 - Rv1616 0.31 -1.9
1,815,873 + Rv1616 0.48 -1.6
1,816,059 + +1.0
1,816,160 + +0.5

Or see this region's nucleotide sequence