Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1541c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1539 and Rv1540 overlap by 8 nucleotidesRv1540 and Rv1541c are separated by 6 nucleotidesRv1541c and Rv1542c are separated by 54 nucleotidesRv1542c and Rv1543 are separated by 227 nucleotides Rv1539: Rv1539 - Probable lipoprotein signal peptidase LspA, at 1,742,244 to 1,742,852 Rv1539 Rv1540: Rv1540 - Conserved hypothetical protein member of yabO/yceC/yfiI family, at 1,742,845 to 1,743,771 Rv1540 Rv1541c: Rv1541c - Possible lipoprotein LprI, at 1,743,778 to 1,744,371 Rv1541c Rv1542c: Rv1542c - Hemoglobin GlbN, at 1,744,426 to 1,744,836 Rv1542c Rv1543: Rv1543 - Possible fatty acyl-CoA reductase, at 1,745,064 to 1,746,089 Rv1543 Position (kb) 1743 1744 1745Strain fitness (log2 ratio) -1 0 1 2at 1742.797 kb on + strandat 1742.797 kb on + strandat 1742.797 kb on + strandat 1742.827 kb on + strandat 1742.827 kb on + strandat 1742.827 kb on + strandat 1742.827 kb on + strandat 1742.827 kb on + strandat 1743.845 kb on + strand, within Rv1541cat 1743.846 kb on - strand, within Rv1541cat 1743.846 kb on - strand, within Rv1541cat 1743.957 kb on - strand, within Rv1541cat 1744.065 kb on - strand, within Rv1541cat 1744.250 kb on - strand, within Rv1541cat 1744.383 kb on - strandat 1744.578 kb on + strand, within Rv1542cat 1744.579 kb on - strand, within Rv1542cat 1744.739 kb on + strand, within Rv1542cat 1744.739 kb on + strand, within Rv1542cat 1744.739 kb on + strand, within Rv1542cat 1744.740 kb on - strand, within Rv1542cat 1744.790 kb on + strand, within Rv1542cat 1745.004 kb on - strandat 1745.004 kb on - strandat 1745.006 kb on + strandat 1745.007 kb on - strandat 1745.163 kb on + strandat 1745.163 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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1,742,797 + +0.4
1,742,797 + -0.6
1,742,797 + +1.0
1,742,827 + -0.8
1,742,827 + +0.4
1,742,827 + +1.8
1,742,827 + -0.4
1,742,827 + +0.0
1,743,845 + Rv1541c 0.11 +0.7
1,743,846 - Rv1541c 0.11 +0.6
1,743,846 - Rv1541c 0.11 -0.0
1,743,957 - Rv1541c 0.30 +0.2
1,744,065 - Rv1541c 0.48 +0.7
1,744,250 - Rv1541c 0.79 -0.6
1,744,383 - -1.3
1,744,578 + Rv1542c 0.37 -0.1
1,744,579 - Rv1542c 0.37 +0.2
1,744,739 + Rv1542c 0.76 -0.5
1,744,739 + Rv1542c 0.76 -1.2
1,744,739 + Rv1542c 0.76 -0.2
1,744,740 - Rv1542c 0.76 +0.1
1,744,790 + Rv1542c 0.89 -0.3
1,745,004 - -1.3
1,745,004 - +0.6
1,745,006 + +0.6
1,745,007 - -0.5
1,745,163 + -0.6
1,745,163 + -0.5

Or see this region's nucleotide sequence