Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1364c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1363c and Rv1364c are separated by 290 nucleotidesRv1364c and Rv1365c are separated by 138 nucleotidesRv1365c and Rv1366 are separated by 220 nucleotides Rv1363c: Rv1363c - Possible membrane protein, at 1,534,607 to 1,535,392 Rv1363c Rv1364c: Rv1364c - Possible sigma factor regulatory protein, at 1,535,683 to 1,537,644 Rv1364c Rv1365c: Rv1365c - Anti-anti-sigma factor RsfA (anti-sigma factor antagonist) (regulator of sigma F A), at 1,537,783 to 1,538,169 Rv1365c Rv1366: Rv1366 - Hypothetical protein, at 1,538,390 to 1,539,211 Rv1366 Position (kb) 1535 1536 1537 1538Strain fitness (log2 ratio) -2 -1 0 1at 1535.155 kb on - strand, within Rv1363cat 1535.155 kb on - strand, within Rv1363cat 1535.173 kb on - strand, within Rv1363cat 1535.199 kb on + strand, within Rv1363cat 1535.400 kb on - strandat 1535.413 kb on - strandat 1535.447 kb on + strandat 1535.461 kb on - strandat 1535.572 kb on + strandat 1535.572 kb on + strandat 1536.081 kb on + strand, within Rv1364cat 1536.082 kb on - strand, within Rv1364cat 1536.133 kb on + strand, within Rv1364cat 1536.668 kb on + strand, within Rv1364cat 1536.669 kb on - strand, within Rv1364cat 1536.761 kb on + strand, within Rv1364cat 1536.892 kb on - strand, within Rv1364cat 1537.101 kb on - strand, within Rv1364cat 1537.165 kb on - strand, within Rv1364cat 1537.430 kb on + strand, within Rv1364cat 1537.431 kb on - strand, within Rv1364cat 1537.595 kb on - strandat 1537.595 kb on - strandat 1537.672 kb on - strandat 1537.784 kb on + strandat 1537.784 kb on + strandat 1537.785 kb on - strandat 1537.819 kb on + strandat 1537.820 kb on - strandat 1537.839 kb on - strand, within Rv1365cat 1538.248 kb on + strandat 1538.248 kb on + strandat 1538.248 kb on + strandat 1538.248 kb on + strandat 1538.249 kb on - strandat 1538.249 kb on - strandat 1538.250 kb on + strandat 1538.250 kb on + strandat 1538.251 kb on - strandat 1538.251 kb on - strandat 1538.274 kb on - strandat 1538.276 kb on - strandat 1538.397 kb on + strandat 1538.407 kb on - strandat 1538.407 kb on - strandat 1538.604 kb on + strand, within Rv1366at 1538.605 kb on - strand, within Rv1366at 1538.605 kb on - strand, within Rv1366at 1538.605 kb on - strand, within Rv1366at 1538.605 kb on - strand, within Rv1366at 1538.611 kb on + strand, within Rv1366at 1538.611 kb on + strand, within Rv1366

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
remove
1,535,155 - Rv1363c 0.70 -0.5
1,535,155 - Rv1363c 0.70 -0.1
1,535,173 - Rv1363c 0.72 -0.6
1,535,199 + Rv1363c 0.75 -0.5
1,535,400 - +0.2
1,535,413 - +0.2
1,535,447 + +0.1
1,535,461 - -0.7
1,535,572 + -1.5
1,535,572 + +0.4
1,536,081 + Rv1364c 0.20 -0.9
1,536,082 - Rv1364c 0.20 -0.8
1,536,133 + Rv1364c 0.23 -0.4
1,536,668 + Rv1364c 0.50 -2.0
1,536,669 - Rv1364c 0.50 -0.6
1,536,761 + Rv1364c 0.55 -1.4
1,536,892 - Rv1364c 0.62 -0.9
1,537,101 - Rv1364c 0.72 -0.6
1,537,165 - Rv1364c 0.76 -0.5
1,537,430 + Rv1364c 0.89 -0.3
1,537,431 - Rv1364c 0.89 -0.8
1,537,595 - +0.3
1,537,595 - -0.4
1,537,672 - -0.9
1,537,784 + +0.4
1,537,784 + +0.3
1,537,785 - -0.1
1,537,819 + -1.4
1,537,820 - -0.2
1,537,839 - Rv1365c 0.14 +0.9
1,538,248 + -0.6
1,538,248 + -0.5
1,538,248 + +0.6
1,538,248 + -0.9
1,538,249 - +0.1
1,538,249 - -0.4
1,538,250 + -0.5
1,538,250 + -0.5
1,538,251 - +1.1
1,538,251 - +0.0
1,538,274 - -0.8
1,538,276 - -0.1
1,538,397 + -0.6
1,538,407 - +1.0
1,538,407 - -1.3
1,538,604 + Rv1366 0.26 +0.6
1,538,605 - Rv1366 0.26 -0.3
1,538,605 - Rv1366 0.26 -1.8
1,538,605 - Rv1366 0.26 +0.1
1,538,605 - Rv1366 0.26 -1.2
1,538,611 + Rv1366 0.27 -0.5
1,538,611 + Rv1366 0.27 +1.0

Or see this region's nucleotide sequence