Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1244

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1243c and Rv1244 are separated by 179 nucleotidesRv1244 and Rv1245c are separated by 80 nucleotidesRv1245c and Rv1246c are separated by 56 nucleotides Rv1243c: Rv1243c - PE-PGRS family protein PE_PGRS23, at 1,384,989 to 1,386,677 Rv1243c Rv1244: Rv1244 - Probable lipoprotein LpqZ, at 1,386,857 to 1,387,717 Rv1244 Rv1245c: Rv1245c - Probable short-chain type dehydrogenase/reductase, at 1,387,798 to 1,388,628 Rv1245c Rv1246c: Rv1246c - Toxin RelE, at 1,388,685 to 1,388,978 Rv1246c Position (kb) 1386 1387 1388Strain fitness (log2 ratio) -2 -1 0 1 2at 1386.027 kb on + strand, within Rv1243cat 1386.120 kb on + strand, within Rv1243cat 1386.239 kb on + strand, within Rv1243cat 1386.240 kb on - strand, within Rv1243cat 1386.268 kb on + strand, within Rv1243cat 1386.268 kb on + strand, within Rv1243cat 1386.418 kb on + strand, within Rv1243cat 1386.493 kb on + strand, within Rv1243cat 1386.493 kb on + strand, within Rv1243cat 1386.537 kb on + strandat 1386.537 kb on + strandat 1386.537 kb on + strandat 1386.537 kb on + strandat 1386.537 kb on + strandat 1386.594 kb on - strandat 1386.670 kb on + strandat 1386.670 kb on + strandat 1386.670 kb on + strandat 1386.670 kb on + strandat 1386.670 kb on + strandat 1386.671 kb on - strandat 1386.837 kb on - strandat 1387.007 kb on + strand, within Rv1244at 1387.008 kb on - strand, within Rv1244at 1387.170 kb on + strand, within Rv1244at 1387.170 kb on + strand, within Rv1244at 1387.170 kb on + strand, within Rv1244at 1387.170 kb on + strand, within Rv1244at 1387.170 kb on + strand, within Rv1244at 1387.171 kb on - strand, within Rv1244at 1387.172 kb on + strand, within Rv1244at 1387.850 kb on + strandat 1387.987 kb on - strand, within Rv1245cat 1388.367 kb on - strand, within Rv1245cat 1388.367 kb on - strand, within Rv1245cat 1388.417 kb on - strand, within Rv1245cat 1388.438 kb on - strand, within Rv1245cat 1388.438 kb on - strand, within Rv1245cat 1388.633 kb on + strandat 1388.633 kb on + strandat 1388.633 kb on + strandat 1388.633 kb on + strandat 1388.634 kb on - strandat 1388.686 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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1,386,027 + Rv1243c 0.61 +1.0
1,386,120 + Rv1243c 0.67 +1.0
1,386,239 + Rv1243c 0.74 +0.0
1,386,240 - Rv1243c 0.74 -0.4
1,386,268 + Rv1243c 0.76 -1.0
1,386,268 + Rv1243c 0.76 +1.2
1,386,418 + Rv1243c 0.85 -0.6
1,386,493 + Rv1243c 0.89 +1.4
1,386,493 + Rv1243c 0.89 -0.5
1,386,537 + +1.8
1,386,537 + +0.7
1,386,537 + +0.7
1,386,537 + +0.0
1,386,537 + -0.0
1,386,594 - +0.3
1,386,670 + +2.0
1,386,670 + -0.2
1,386,670 + +0.0
1,386,670 + -0.2
1,386,670 + -0.5
1,386,671 - -0.1
1,386,837 - -0.2
1,387,007 + Rv1244 0.17 -0.8
1,387,008 - Rv1244 0.18 -0.3
1,387,170 + Rv1244 0.36 +0.1
1,387,170 + Rv1244 0.36 -0.5
1,387,170 + Rv1244 0.36 +0.0
1,387,170 + Rv1244 0.36 -1.1
1,387,170 + Rv1244 0.36 -1.5
1,387,171 - Rv1244 0.36 -1.9
1,387,172 + Rv1244 0.37 -0.8
1,387,850 + -0.5
1,387,987 - Rv1245c 0.23 -0.4
1,388,367 - Rv1245c 0.68 +0.9
1,388,367 - Rv1245c 0.68 +0.0
1,388,417 - Rv1245c 0.74 +1.4
1,388,438 - Rv1245c 0.77 +0.7
1,388,438 - Rv1245c 0.77 +0.6
1,388,633 + -0.4
1,388,633 + -0.4
1,388,633 + -0.3
1,388,633 + -1.3
1,388,634 - -0.6
1,388,686 + -1.1

Or see this region's nucleotide sequence