Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1127c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1125 and Rv1126c are separated by 3 nucleotidesRv1126c and Rv1127c overlap by 4 nucleotidesRv1127c and Rv1128c are separated by 212 nucleotides Rv1125: Rv1125 - Conserved hypothetical protein, at 1,248,082 to 1,249,326 Rv1125 Rv1126c: Rv1126c - Conserved protein, at 1,249,330 to 1,249,935 Rv1126c Rv1127c: Rv1127c - Probable pyruvate, phosphate dikinase PpdK, at 1,249,932 to 1,251,404 Rv1127c Rv1128c: Rv1128c - Conserved hypothetical protein, at 1,251,617 to 1,252,972 Rv1128c Position (kb) 1249 1250 1251 1252Strain fitness (log2 ratio) -1 0 1 2at 1250.902 kb on + strand, within Rv1127cat 1250.947 kb on + strand, within Rv1127cat 1251.322 kb on + strandat 1251.323 kb on - strandat 1251.421 kb on + strandat 1251.425 kb on + strandat 1251.426 kb on - strandat 1251.515 kb on + strandat 1251.667 kb on + strandat 1252.156 kb on + strand, within Rv1128cat 1252.380 kb on - strand, within Rv1128c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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1,250,902 + Rv1127c 0.66 -1.4
1,250,947 + Rv1127c 0.69 -0.7
1,251,322 + +2.0
1,251,323 - -1.7
1,251,421 + -1.4
1,251,425 + -1.0
1,251,426 - -0.5
1,251,515 + -0.6
1,251,667 + +0.0
1,252,156 + Rv1128c 0.40 -1.6
1,252,380 - Rv1128c 0.56 +0.1

Or see this region's nucleotide sequence