Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0394c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0393 and Rv0394c are separated by 15 nucleotidesRv0394c and Rv0395 are separated by 98 nucleotidesRv0395 and Rv0396 are separated by 5 nucleotidesRv0396 and Rv0397 are separated by 73 nucleotides Rv0393: Rv0393 - Conserved 13E12 repeat family protein, at 472,781 to 474,106 Rv0393 Rv0394c: Rv0394c - Possible secreted protein, at 474,122 to 474,841 Rv0394c Rv0395: Rv0395 - Hypothetical protein, at 474,940 to 475,344 Rv0395 Rv0396: Rv0396 - Hypothetical protein, at 475,350 to 475,742 Rv0396 Rv0397: Rv0397 - Conserved 13E12 repeat family protein, at 475,816 to 476,184 Rv0397 Position (kb) 474 475Strain fitness (log2 ratio) -2 -1 0 1 2at 473.213 kb on + strand, within Rv0393at 473.214 kb on - strand, within Rv0393at 473.214 kb on - strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.225 kb on + strand, within Rv0393at 473.226 kb on - strand, within Rv0393at 474.225 kb on + strand, within Rv0394cat 474.226 kb on - strand, within Rv0394cat 474.386 kb on - strand, within Rv0394cat 474.476 kb on - strand, within Rv0394cat 474.593 kb on - strand, within Rv0394cat 474.698 kb on + strand, within Rv0394cat 474.841 kb on + strandat 474.854 kb on - strandat 474.854 kb on - strandat 474.854 kb on - strandat 474.854 kb on - strandat 475.140 kb on + strand, within Rv0395at 475.227 kb on + strand, within Rv0395at 475.260 kb on - strand, within Rv0395at 475.326 kb on - strandat 475.326 kb on - strandat 475.342 kb on + strandat 475.343 kb on - strandat 475.343 kb on - strandat 475.369 kb on + strandat 475.438 kb on - strand, within Rv0396at 475.438 kb on - strand, within Rv0396

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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473,213 + Rv0393 0.33 -1.1
473,214 - Rv0393 0.33 +0.1
473,214 - Rv0393 0.33 -2.1
473,225 + Rv0393 0.33 -1.1
473,225 + Rv0393 0.33 +0.2
473,225 + Rv0393 0.33 -0.5
473,226 - Rv0393 0.34 +0.0
474,225 + Rv0394c 0.14 -0.4
474,226 - Rv0394c 0.14 -1.5
474,386 - Rv0394c 0.37 -0.5
474,476 - Rv0394c 0.49 -0.5
474,593 - Rv0394c 0.65 -0.6
474,698 + Rv0394c 0.80 +2.0
474,841 + +0.1
474,854 - +0.2
474,854 - -0.2
474,854 - -0.4
474,854 - +0.5
475,140 + Rv0395 0.49 -0.6
475,227 + Rv0395 0.71 -0.2
475,260 - Rv0395 0.79 -0.4
475,326 - +0.6
475,326 - +0.1
475,342 + +0.7
475,343 - -0.1
475,343 - +0.6
475,369 + +0.6
475,438 - Rv0396 0.22 +2.5
475,438 - Rv0396 0.22 +0.1

Or see this region's nucleotide sequence