Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3621c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3618 and Rv3619c are separated by 98 nucleotidesRv3619c and Rv3620c are separated by 26 nucleotidesRv3620c and Rv3621c are separated by 56 nucleotidesRv3621c and Rv3622c are separated by 9 nucleotidesRv3622c and Rv3623 are separated by 328 nucleotides Rv3618: Rv3618 - Possible monooxygenase, at 4,058,698 to 4,059,885 Rv3618 Rv3619c: Rv3619c - Putative ESAT-6 like protein EsxV (ESAT-6 like protein 1), at 4,059,984 to 4,060,268 Rv3619c Rv3620c: Rv3620c - Putative ESAT-6 like protein EsxW (ESAT-6 like protein 10), at 4,060,295 to 4,060,591 Rv3620c Rv3621c: Rv3621c - PPE family protein PPE65, at 4,060,648 to 4,061,889 Rv3621c Rv3622c: Rv3622c - PE family protein PE32, at 4,061,899 to 4,062,198 Rv3622c Rv3623: Rv3623 - Probable conserved lipoprotein LpqG, at 4,062,527 to 4,063,249 Rv3623 Position (kb) 4060 4061 4062Strain fitness (log2 ratio) -2 -1 0 1 2at 4059.712 kb on + strand, within Rv3618at 4059.712 kb on + strand, within Rv3618at 4059.713 kb on - strand, within Rv3618at 4059.713 kb on - strand, within Rv3618at 4059.742 kb on + strand, within Rv3618at 4059.790 kb on - strandat 4059.923 kb on - strandat 4059.923 kb on - strandat 4059.973 kb on + strandat 4059.974 kb on - strandat 4059.974 kb on - strandat 4060.591 kb on + strandat 4060.641 kb on + strandat 4060.641 kb on + strandat 4060.642 kb on - strandat 4060.716 kb on + strandat 4061.031 kb on - strand, within Rv3621cat 4061.031 kb on - strand, within Rv3621cat 4061.427 kb on - strand, within Rv3621cat 4061.432 kb on + strand, within Rv3621cat 4061.432 kb on + strand, within Rv3621cat 4061.432 kb on + strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.433 kb on - strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.597 kb on + strand, within Rv3621cat 4061.598 kb on - strand, within Rv3621cat 4061.753 kb on + strand, within Rv3621cat 4061.754 kb on - strand, within Rv3621cat 4061.840 kb on + strandat 4061.840 kb on + strandat 4061.840 kb on + strandat 4061.841 kb on - strandat 4061.841 kb on - strandat 4061.841 kb on - strandat 4061.841 kb on - strandat 4061.939 kb on + strand, within Rv3622cat 4061.940 kb on - strand, within Rv3622cat 4061.940 kb on - strand, within Rv3622cat 4061.940 kb on - strand, within Rv3622cat 4062.004 kb on - strand, within Rv3622cat 4062.014 kb on + strand, within Rv3622cat 4062.014 kb on + strand, within Rv3622cat 4062.201 kb on + strandat 4062.201 kb on + strandat 4062.202 kb on - strandat 4062.215 kb on + strandat 4062.233 kb on + strandat 4062.233 kb on + strandat 4062.330 kb on - strandat 4062.514 kb on + strandat 4062.839 kb on + strand, within Rv3623at 4062.839 kb on + strand, within Rv3623at 4062.840 kb on - strand, within Rv3623

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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4,059,712 + Rv3618 0.85 -1.2
4,059,712 + Rv3618 0.85 -2.1
4,059,713 - Rv3618 0.85 +0.7
4,059,713 - Rv3618 0.85 +1.5
4,059,742 + Rv3618 0.88 +0.2
4,059,790 - -0.3
4,059,923 - -0.2
4,059,923 - -0.2
4,059,973 + -0.5
4,059,974 - +0.7
4,059,974 - -0.4
4,060,591 + -1.7
4,060,641 + -0.0
4,060,641 + -0.7
4,060,642 - -0.1
4,060,716 + +0.3
4,061,031 - Rv3621c 0.31 +1.3
4,061,031 - Rv3621c 0.31 -1.0
4,061,427 - Rv3621c 0.63 +0.0
4,061,432 + Rv3621c 0.63 +0.2
4,061,432 + Rv3621c 0.63 -0.4
4,061,432 + Rv3621c 0.63 +0.1
4,061,433 - Rv3621c 0.63 +2.7
4,061,433 - Rv3621c 0.63 -0.4
4,061,433 - Rv3621c 0.63 -0.3
4,061,433 - Rv3621c 0.63 +0.7
4,061,433 - Rv3621c 0.63 -0.0
4,061,433 - Rv3621c 0.63 -0.1
4,061,597 + Rv3621c 0.76 +2.1
4,061,597 + Rv3621c 0.76 -0.3
4,061,597 + Rv3621c 0.76 +2.7
4,061,597 + Rv3621c 0.76 -0.0
4,061,598 - Rv3621c 0.76 +0.1
4,061,753 + Rv3621c 0.89 -0.4
4,061,754 - Rv3621c 0.89 +0.3
4,061,840 + -0.7
4,061,840 + -0.4
4,061,840 + +0.2
4,061,841 - -0.5
4,061,841 - +0.2
4,061,841 - +0.0
4,061,841 - -0.5
4,061,939 + Rv3622c 0.13 -0.2
4,061,940 - Rv3622c 0.14 -0.2
4,061,940 - Rv3622c 0.14 -1.0
4,061,940 - Rv3622c 0.14 -0.6
4,062,004 - Rv3622c 0.35 +0.1
4,062,014 + Rv3622c 0.38 +1.5
4,062,014 + Rv3622c 0.38 -0.4
4,062,201 + -0.5
4,062,201 + +0.0
4,062,202 - -1.9
4,062,215 + +0.6
4,062,233 + -0.7
4,062,233 + +0.1
4,062,330 - -0.4
4,062,514 + +1.0
4,062,839 + Rv3623 0.43 -0.5
4,062,839 + Rv3623 0.43 +0.8
4,062,840 - Rv3623 0.43 -0.1

Or see this region's nucleotide sequence