Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3471c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3470c and Rv3471c are separated by 5 nucleotidesRv3471c and Rv3472 are separated by 20 nucleotidesRv3472 and Rv3473c are separated by 79 nucleotides Rv3470c: Rv3470c - Probable acetolactate synthase (large subunit) IlvB2 (AHAS) (acetohydroxy-acid synthase large subunit) (ALS), at 3,887,144 to 3,888,802 Rv3470c Rv3471c: Rv3471c - Conserved hypothetical protein, at 3,888,808 to 3,889,341 Rv3471c Rv3472: Rv3472 - Conserved protein, at 3,889,362 to 3,889,868 Rv3472 Rv3473c: Rv3473c - Possible peroxidase BpoA (non-haem peroxidase), at 3,889,948 to 3,890,733 Rv3473c Position (kb) 3888 3889 3890Strain fitness (log2 ratio) -1 0 1at 3887.994 kb on + strand, within Rv3470cat 3887.995 kb on - strand, within Rv3470cat 3888.020 kb on + strand, within Rv3470cat 3888.021 kb on - strand, within Rv3470cat 3888.246 kb on - strand, within Rv3470cat 3888.523 kb on + strand, within Rv3470cat 3888.738 kb on - strandat 3888.746 kb on + strandat 3888.863 kb on - strand, within Rv3471cat 3888.866 kb on + strand, within Rv3471cat 3888.910 kb on + strand, within Rv3471cat 3888.910 kb on + strand, within Rv3471cat 3888.910 kb on + strand, within Rv3471cat 3888.911 kb on - strand, within Rv3471cat 3888.911 kb on - strand, within Rv3471cat 3889.393 kb on + strandat 3889.393 kb on + strandat 3889.528 kb on + strand, within Rv3472at 3889.528 kb on + strand, within Rv3472at 3889.536 kb on + strand, within Rv3472at 3889.593 kb on + strand, within Rv3472at 3889.662 kb on + strand, within Rv3472at 3889.897 kb on + strandat 3889.897 kb on + strandat 3889.981 kb on + strandat 3889.982 kb on - strandat 3890.025 kb on + strandat 3890.025 kb on + strandat 3890.025 kb on + strandat 3890.026 kb on - strandat 3890.200 kb on + strand, within Rv3473cat 3890.201 kb on - strand, within Rv3473cat 3890.220 kb on + strand, within Rv3473cat 3890.221 kb on - strand, within Rv3473cat 3890.253 kb on - strand, within Rv3473cat 3890.253 kb on - strand, within Rv3473cat 3890.327 kb on + strand, within Rv3473cat 3890.327 kb on + strand, within Rv3473cat 3890.328 kb on - strand, within Rv3473c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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3,887,994 + Rv3470c 0.51 -0.0
3,887,995 - Rv3470c 0.51 -0.1
3,888,020 + Rv3470c 0.53 +0.6
3,888,021 - Rv3470c 0.53 +0.9
3,888,246 - Rv3470c 0.66 +0.1
3,888,523 + Rv3470c 0.83 -0.0
3,888,738 - +0.6
3,888,746 + -0.6
3,888,863 - Rv3471c 0.10 +1.4
3,888,866 + Rv3471c 0.11 +0.0
3,888,910 + Rv3471c 0.19 +0.5
3,888,910 + Rv3471c 0.19 -0.2
3,888,910 + Rv3471c 0.19 -0.2
3,888,911 - Rv3471c 0.19 +0.6
3,888,911 - Rv3471c 0.19 +0.4
3,889,393 + -0.5
3,889,393 + +0.7
3,889,528 + Rv3472 0.33 -0.1
3,889,528 + Rv3472 0.33 -0.4
3,889,536 + Rv3472 0.34 -0.3
3,889,593 + Rv3472 0.46 +0.0
3,889,662 + Rv3472 0.59 +0.9
3,889,897 + +0.1
3,889,897 + -1.0
3,889,981 + -0.0
3,889,982 - -1.5
3,890,025 + -1.0
3,890,025 + -0.2
3,890,025 + +0.1
3,890,026 - -1.1
3,890,200 + Rv3473c 0.32 -0.4
3,890,201 - Rv3473c 0.32 +1.2
3,890,220 + Rv3473c 0.35 -0.1
3,890,221 - Rv3473c 0.35 +0.2
3,890,253 - Rv3473c 0.39 -0.6
3,890,253 - Rv3473c 0.39 +1.1
3,890,327 + Rv3473c 0.48 -0.1
3,890,327 + Rv3473c 0.48 -0.7
3,890,328 - Rv3473c 0.48 +0.0

Or see this region's nucleotide sequence