Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2685

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2684 and Rv2685 are separated by 79 nucleotidesRv2685 and Rv2686c are separated by 10 nucleotidesRv2686c and Rv2687c overlap by 4 nucleotides Rv2684: Rv2684 - Probable arsenic-transport integral membrane protein ArsA, at 3,000,614 to 3,001,903 Rv2684 Rv2685: Rv2685 - Probable arsenic-transport integral membrane protein ArsB1, at 3,001,983 to 3,003,269 Rv2685 Rv2686c: Rv2686c - Antibiotic-transport integral membrane leucine and alanine and valine rich protein ABC transporter, at 3,003,280 to 3,004,038 Rv2686c Rv2687c: Rv2687c - Antibiotic-transport integral membrane leucine and valine rich protein ABC transporter, at 3,004,035 to 3,004,748 Rv2687c Position (kb) 3001 3002 3003 3004Strain fitness (log2 ratio) -2 -1 0 1 2at 3001.156 kb on - strand, within Rv2684at 3001.421 kb on + strand, within Rv2684at 3001.425 kb on + strand, within Rv2684at 3001.425 kb on + strand, within Rv2684at 3001.426 kb on - strand, within Rv2684at 3001.426 kb on - strand, within Rv2684at 3001.569 kb on + strand, within Rv2684at 3001.569 kb on + strand, within Rv2684at 3001.569 kb on + strand, within Rv2684at 3001.912 kb on - strandat 3001.912 kb on - strandat 3001.912 kb on - strandat 3001.928 kb on + strandat 3001.929 kb on - strandat 3001.929 kb on - strandat 3002.121 kb on + strand, within Rv2685at 3002.122 kb on - strand, within Rv2685at 3002.218 kb on - strand, within Rv2685at 3002.218 kb on - strand, within Rv2685at 3002.218 kb on - strand, within Rv2685at 3002.218 kb on - strand, within Rv2685at 3002.359 kb on + strand, within Rv2685at 3002.360 kb on - strand, within Rv2685at 3002.923 kb on + strand, within Rv2685at 3003.268 kb on - strandat 3003.336 kb on - strandat 3003.356 kb on + strand, within Rv2686cat 3003.656 kb on + strand, within Rv2686cat 3003.657 kb on - strand, within Rv2686cat 3004.064 kb on - strandat 3004.213 kb on + strand, within Rv2687cat 3004.214 kb on - strand, within Rv2687c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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3,001,156 - Rv2684 0.42 -0.3
3,001,421 + Rv2684 0.63 -0.5
3,001,425 + Rv2684 0.63 +2.7
3,001,425 + Rv2684 0.63 +0.3
3,001,426 - Rv2684 0.63 -0.6
3,001,426 - Rv2684 0.63 +1.7
3,001,569 + Rv2684 0.74 +0.5
3,001,569 + Rv2684 0.74 -0.0
3,001,569 + Rv2684 0.74 -2.3
3,001,912 - -0.1
3,001,912 - -0.4
3,001,912 - +1.1
3,001,928 + +0.0
3,001,929 - -0.1
3,001,929 - -0.4
3,002,121 + Rv2685 0.11 -1.0
3,002,122 - Rv2685 0.11 -0.3
3,002,218 - Rv2685 0.18 +0.3
3,002,218 - Rv2685 0.18 -0.1
3,002,218 - Rv2685 0.18 -0.7
3,002,218 - Rv2685 0.18 -0.2
3,002,359 + Rv2685 0.29 -0.9
3,002,360 - Rv2685 0.29 -1.3
3,002,923 + Rv2685 0.73 -0.6
3,003,268 - -0.3
3,003,336 - -0.1
3,003,356 + Rv2686c 0.10 +0.4
3,003,656 + Rv2686c 0.50 -0.1
3,003,657 - Rv2686c 0.50 -0.3
3,004,064 - +0.0
3,004,213 + Rv2687c 0.25 +0.3
3,004,214 - Rv2687c 0.25 -0.8

Or see this region's nucleotide sequence