Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2587c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2586c and Rv2587c are separated by 3 nucleotidesRv2587c and Rv2588c are separated by 109 nucleotidesRv2588c and Rv2589 are separated by 166 nucleotides Rv2586c: Rv2586c - Probable protein-export membrane protein SecF, at 2,912,683 to 2,914,011 Rv2586c Rv2587c: Rv2587c - Probable protein-export membrane protein SecD, at 2,914,015 to 2,915,736 Rv2587c Rv2588c: Rv2588c - Probable conserved membrane protein secretion factor YajC, at 2,915,846 to 2,916,193 Rv2588c Rv2589: Rv2589 - 4-aminobutyrate aminotransferase GabT (gamma-amino-N-butyrate transaminase) (GABA transaminase) (glutamate:succinic semialdehyde transaminase) (GABA aminotransferase) (GABA-at), at 2,916,360 to 2,917,709 Rv2589 Position (kb) 2914 2915 2916Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2915.746 kb on - strandat 2915.769 kb on - strandat 2915.784 kb on + strandat 2915.784 kb on + strandat 2915.784 kb on + strandat 2915.784 kb on + strandat 2915.784 kb on + strandat 2915.784 kb on + strandat 2915.784 kb on + strandat 2915.785 kb on - strandat 2915.785 kb on - strandat 2915.785 kb on - strandat 2915.785 kb on - strandat 2915.785 kb on - strandat 2915.785 kb on - strandat 2916.059 kb on + strand, within Rv2588cat 2916.138 kb on + strand, within Rv2588cat 2916.138 kb on + strand, within Rv2588cat 2916.138 kb on + strand, within Rv2588cat 2916.139 kb on - strand, within Rv2588cat 2916.208 kb on + strandat 2916.209 kb on - strandat 2916.209 kb on - strandat 2916.209 kb on - strandat 2916.209 kb on - strandat 2916.215 kb on - strandat 2916.215 kb on - strandat 2916.259 kb on + strandat 2916.259 kb on + strandat 2916.313 kb on + strandat 2916.624 kb on - strand, within Rv2589at 2916.651 kb on + strand, within Rv2589at 2916.660 kb on + strand, within Rv2589at 2916.660 kb on + strand, within Rv2589at 2916.661 kb on - strand, within Rv2589at 2916.661 kb on - strand, within Rv2589at 2916.661 kb on - strand, within Rv2589at 2916.661 kb on - strand, within Rv2589at 2916.661 kb on - strand, within Rv2589at 2916.661 kb on - strand, within Rv2589at 2916.692 kb on + strand, within Rv2589

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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2,915,746 - -3.0
2,915,769 - -0.2
2,915,784 + -0.6
2,915,784 + +0.6
2,915,784 + -1.0
2,915,784 + -0.3
2,915,784 + +0.8
2,915,784 + -0.1
2,915,784 + -1.0
2,915,785 - -0.6
2,915,785 - +1.7
2,915,785 - +0.4
2,915,785 - +0.5
2,915,785 - +0.5
2,915,785 - +0.1
2,916,059 + Rv2588c 0.61 +0.3
2,916,138 + Rv2588c 0.84 +0.6
2,916,138 + Rv2588c 0.84 +0.6
2,916,138 + Rv2588c 0.84 -1.3
2,916,139 - Rv2588c 0.84 +1.1
2,916,208 + -0.8
2,916,209 - -0.2
2,916,209 - -0.5
2,916,209 - -0.9
2,916,209 - +0.5
2,916,215 - -0.5
2,916,215 - +0.2
2,916,259 + -0.7
2,916,259 + +2.3
2,916,313 + -0.0
2,916,624 - Rv2589 0.20 -0.5
2,916,651 + Rv2589 0.22 -1.0
2,916,660 + Rv2589 0.22 -1.1
2,916,660 + Rv2589 0.22 -1.0
2,916,661 - Rv2589 0.22 +0.8
2,916,661 - Rv2589 0.22 -0.9
2,916,661 - Rv2589 0.22 -0.8
2,916,661 - Rv2589 0.22 +1.6
2,916,661 - Rv2589 0.22 -2.0
2,916,661 - Rv2589 0.22 -1.7
2,916,692 + Rv2589 0.25 -0.5

Or see this region's nucleotide sequence