Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1261c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1260 and Rv1261c are separated by 125 nucleotidesRv1261c and Rv1262c are separated by 4 nucleotidesRv1262c and Rv1263 are separated by 58 nucleotides Rv1260: Rv1260 - Probable oxidoreductase, at 1,408,240 to 1,409,358 Rv1260 Rv1261c: Rv1261c - Conserved protein, at 1,409,484 to 1,409,933 Rv1261c Rv1262c: Rv1262c - Hypothetical hit-like protein, at 1,409,938 to 1,410,372 Rv1262c Rv1263: Rv1263 - Probable amidase AmiB2 (aminohydrolase), at 1,410,431 to 1,411,819 Rv1263 Position (kb) 1409 1410Strain fitness (log2 ratio) -1 0 1 2at 1409.014 kb on + strand, within Rv1260at 1409.015 kb on - strand, within Rv1260at 1409.227 kb on + strand, within Rv1260at 1409.433 kb on - strandat 1409.433 kb on - strandat 1409.546 kb on - strand, within Rv1261cat 1409.590 kb on + strand, within Rv1261cat 1409.686 kb on + strand, within Rv1261cat 1409.734 kb on + strand, within Rv1261cat 1409.755 kb on + strand, within Rv1261cat 1410.071 kb on - strand, within Rv1262cat 1410.318 kb on - strand, within Rv1262cat 1410.420 kb on - strandat 1410.707 kb on + strand, within Rv1263at 1410.708 kb on - strand, within Rv1263

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
remove
1,409,014 + Rv1260 0.69 +0.6
1,409,015 - Rv1260 0.69 -0.7
1,409,227 + Rv1260 0.88 -0.5
1,409,433 - -1.0
1,409,433 - -0.4
1,409,546 - Rv1261c 0.14 +2.3
1,409,590 + Rv1261c 0.24 +0.0
1,409,686 + Rv1261c 0.45 -1.1
1,409,734 + Rv1261c 0.56 -0.3
1,409,755 + Rv1261c 0.60 +0.3
1,410,071 - Rv1262c 0.31 +0.1
1,410,318 - Rv1262c 0.87 +1.2
1,410,420 - -1.0
1,410,707 + Rv1263 0.20 +0.8
1,410,708 - Rv1263 0.20 +0.9

Or see this region's nucleotide sequence