Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0643c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0642c and Rv0643c are separated by 64 nucleotidesRv0643c and Rv0644c are separated by 147 nucleotides Rv0642c: Rv0642c - Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase), at 736,298 to 737,203 Rv0642c Rv0643c: Rv0643c - Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase), at 737,268 to 738,149 Rv0643c Rv0644c: Rv0644c - Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase), at 738,297 to 739,160 Rv0644c Position (kb) 737 738 739Strain fitness (log2 ratio) -2 -1 0 1 2 3 4 5at 736.278 kb on + strandat 736.363 kb on - strandat 736.384 kb on - strandat 736.384 kb on - strandat 736.401 kb on + strand, within Rv0642cat 736.482 kb on + strand, within Rv0642cat 736.580 kb on + strand, within Rv0642cat 737.029 kb on - strand, within Rv0642cat 737.226 kb on - strandat 737.302 kb on + strandat 737.302 kb on + strandat 737.339 kb on - strandat 737.339 kb on - strandat 737.348 kb on - strandat 737.356 kb on + strandat 737.356 kb on + strandat 737.358 kb on + strand, within Rv0643cat 737.586 kb on + strand, within Rv0643cat 737.586 kb on + strand, within Rv0643cat 737.610 kb on + strand, within Rv0643cat 737.610 kb on + strand, within Rv0643cat 737.611 kb on - strand, within Rv0643cat 737.730 kb on + strand, within Rv0643cat 737.876 kb on - strand, within Rv0643cat 737.876 kb on - strand, within Rv0643cat 737.967 kb on + strand, within Rv0643cat 737.967 kb on + strand, within Rv0643cat 737.968 kb on - strand, within Rv0643cat 738.023 kb on - strand, within Rv0643cat 738.034 kb on + strand, within Rv0643cat 738.034 kb on + strand, within Rv0643cat 738.034 kb on + strand, within Rv0643cat 738.034 kb on + strand, within Rv0643cat 738.085 kb on + strandat 738.202 kb on + strandat 738.203 kb on - strandat 738.274 kb on + strandat 738.275 kb on - strandat 738.298 kb on + strandat 738.376 kb on + strandat 738.385 kb on + strand, within Rv0644cat 738.467 kb on - strand, within Rv0644cat 738.904 kb on + strand, within Rv0644cat 738.904 kb on + strand, within Rv0644cat 738.904 kb on + strand, within Rv0644cat 738.904 kb on + strand, within Rv0644cat 738.904 kb on + strand, within Rv0644cat 738.905 kb on - strand, within Rv0644cat 738.905 kb on - strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.981 kb on + strand, within Rv0644cat 738.982 kb on - strand, within Rv0644cat 738.982 kb on - strand, within Rv0644cat 739.063 kb on + strand, within Rv0644cat 739.064 kb on - strand, within Rv0644cat 739.114 kb on + strandat 739.114 kb on + strandat 739.147 kb on - strandat 739.147 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
remove
736,278 + +0.6
736,363 - +4.9
736,384 - +0.2
736,384 - +0.8
736,401 + Rv0642c 0.11 +0.9
736,482 + Rv0642c 0.20 +3.0
736,580 + Rv0642c 0.31 +5.5
737,029 - Rv0642c 0.81 +1.4
737,226 - +1.1
737,302 + -1.6
737,302 + -0.2
737,339 - +1.1
737,339 - +0.5
737,348 - -0.1
737,356 + +0.4
737,356 + -0.4
737,358 + Rv0643c 0.10 +0.9
737,586 + Rv0643c 0.36 -0.5
737,586 + Rv0643c 0.36 +0.3
737,610 + Rv0643c 0.39 +0.6
737,610 + Rv0643c 0.39 +0.6
737,611 - Rv0643c 0.39 +0.7
737,730 + Rv0643c 0.52 +0.5
737,876 - Rv0643c 0.69 +1.3
737,876 - Rv0643c 0.69 -0.5
737,967 + Rv0643c 0.79 +1.6
737,967 + Rv0643c 0.79 +0.4
737,968 - Rv0643c 0.79 -2.0
738,023 - Rv0643c 0.86 -0.8
738,034 + Rv0643c 0.87 -0.0
738,034 + Rv0643c 0.87 +0.7
738,034 + Rv0643c 0.87 +0.5
738,034 + Rv0643c 0.87 +0.1
738,085 + +0.2
738,202 + -0.7
738,203 - +0.7
738,274 + +0.1
738,275 - +0.4
738,298 + +0.0
738,376 + +0.1
738,385 + Rv0644c 0.10 -1.1
738,467 - Rv0644c 0.20 -0.2
738,904 + Rv0644c 0.70 -0.5
738,904 + Rv0644c 0.70 +0.0
738,904 + Rv0644c 0.70 -0.7
738,904 + Rv0644c 0.70 +1.5
738,904 + Rv0644c 0.70 +0.3
738,905 - Rv0644c 0.70 -0.8
738,905 - Rv0644c 0.70 +1.0
738,981 + Rv0644c 0.79 +0.4
738,981 + Rv0644c 0.79 +2.9
738,981 + Rv0644c 0.79 -1.7
738,981 + Rv0644c 0.79 -0.3
738,981 + Rv0644c 0.79 +0.4
738,981 + Rv0644c 0.79 -0.4
738,981 + Rv0644c 0.79 -1.5
738,982 - Rv0644c 0.79 +0.5
738,982 - Rv0644c 0.79 +0.0
739,063 + Rv0644c 0.89 +0.3
739,064 - Rv0644c 0.89 -0.4
739,114 + +0.3
739,114 + +0.9
739,147 - -0.9
739,147 - -0.0

Or see this region's nucleotide sequence