Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0426c

Experiment: 7H9 with Dimethyl Sulfoxide 1 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0425c and Rv0426c are separated by 51 nucleotidesRv0426c and Rv0427c are separated by 200 nucleotides Rv0425c: Rv0425c - Possible metal cation transporting P-type ATPase CtpH, at 510,702 to 515,321 Rv0425c Rv0426c: Rv0426c - Possible transmembrane protein, at 515,373 to 515,816 Rv0426c Rv0427c: Rv0427c - Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI), at 516,017 to 516,892 Rv0427c Position (kb) 515 516Strain fitness (log2 ratio) -1 0 1at 515.204 kb on + strandat 515.375 kb on - strandat 515.550 kb on + strand, within Rv0426cat 515.660 kb on + strand, within Rv0426cat 515.660 kb on + strand, within Rv0426cat 515.661 kb on - strand, within Rv0426cat 515.847 kb on + strandat 516.199 kb on - strand, within Rv0427cat 516.230 kb on + strand, within Rv0427cat 516.441 kb on + strand, within Rv0427cat 516.669 kb on + strand, within Rv0427c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dimethyl Sulfoxide 1 vol%
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515,204 + +0.1
515,375 - +0.0
515,550 + Rv0426c 0.40 -0.4
515,660 + Rv0426c 0.65 -1.0
515,660 + Rv0426c 0.65 -1.2
515,661 - Rv0426c 0.65 -0.8
515,847 + -0.1
516,199 - Rv0427c 0.21 -1.0
516,230 + Rv0427c 0.24 -1.4
516,441 + Rv0427c 0.48 -0.3
516,669 + Rv0427c 0.74 -0.1

Or see this region's nucleotide sequence