Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2848c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2847c and Rv2848c are separated by 276 nucleotidesRv2848c and Rv2849c overlap by 1 nucleotidesRv2849c and Rv2850c are separated by 20 nucleotides Rv2847c: Rv2847c - Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase, at 3,154,654 to 3,155,871 Rv2847c Rv2848c: Rv2848c - Probable cobyrinic acid A,C-diamide synthase CobB, at 3,156,148 to 3,157,521 Rv2848c Rv2849c: Rv2849c - Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity), at 3,157,521 to 3,158,144 Rv2849c Rv2850c: Rv2850c - Possible magnesium chelatase, at 3,158,165 to 3,160,054 Rv2850c Position (kb) 3156 3157 3158Strain fitness (log2 ratio) -2 -1 0 1at 3155.882 kb on + strandat 3155.882 kb on + strandat 3155.883 kb on - strandat 3156.106 kb on + strandat 3156.162 kb on + strandat 3156.163 kb on - strandat 3156.222 kb on + strandat 3156.223 kb on - strandat 3156.637 kb on - strand, within Rv2848cat 3156.941 kb on + strand, within Rv2848cat 3156.941 kb on + strand, within Rv2848cat 3156.942 kb on - strand, within Rv2848cat 3156.942 kb on - strand, within Rv2848cat 3156.942 kb on - strand, within Rv2848cat 3157.312 kb on - strand, within Rv2848cat 3157.402 kb on + strandat 3157.721 kb on - strand, within Rv2849cat 3157.841 kb on + strand, within Rv2849cat 3157.842 kb on - strand, within Rv2849cat 3158.152 kb on + strandat 3158.153 kb on - strandat 3158.157 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,155,882 + -0.6
3,155,882 + +0.1
3,155,883 - -0.5
3,156,106 + -0.4
3,156,162 + -1.2
3,156,163 - -0.4
3,156,222 + -0.1
3,156,223 - -0.4
3,156,637 - Rv2848c 0.36 -0.4
3,156,941 + Rv2848c 0.58 -0.7
3,156,941 + Rv2848c 0.58 -0.1
3,156,942 - Rv2848c 0.58 -0.5
3,156,942 - Rv2848c 0.58 -0.0
3,156,942 - Rv2848c 0.58 -0.1
3,157,312 - Rv2848c 0.85 -2.0
3,157,402 + -0.8
3,157,721 - Rv2849c 0.32 -0.0
3,157,841 + Rv2849c 0.51 -0.1
3,157,842 - Rv2849c 0.51 -1.0
3,158,152 + -0.9
3,158,153 - +0.1
3,158,157 - -1.0

Or see this region's nucleotide sequence