Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2102

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2101 and Rv2102 are separated by 109 nucleotidesRv2102 and Rv2103c overlap by 22 nucleotidesRv2103c and Rv2104c are separated by 6 nucleotides Rv2101: Rv2101 - Probable helicase HelZ, at 2,360,240 to 2,363,281 Rv2101 Rv2102: Rv2102 - Conserved hypothetical protein, at 2,363,391 to 2,364,107 Rv2102 Rv2103c: Rv2103c - Possible toxin VapC37. Contains PIN domain., at 2,364,086 to 2,364,520 Rv2103c Rv2104c: Rv2104c - Possible antitoxin VapB37, at 2,364,527 to 2,364,781 Rv2104c Position (kb) 2363 2364 2365Strain fitness (log2 ratio) -1 0 1at 2362.475 kb on + strand, within Rv2101at 2362.476 kb on - strand, within Rv2101at 2362.476 kb on - strand, within Rv2101at 2362.547 kb on + strand, within Rv2101at 2362.580 kb on + strand, within Rv2101at 2362.581 kb on - strand, within Rv2101at 2362.883 kb on + strand, within Rv2101at 2363.279 kb on + strandat 2363.279 kb on + strandat 2363.289 kb on + strandat 2363.290 kb on - strandat 2363.290 kb on - strandat 2363.439 kb on + strandat 2363.440 kb on - strandat 2363.440 kb on - strandat 2363.701 kb on + strand, within Rv2102at 2363.763 kb on + strand, within Rv2102at 2363.763 kb on + strand, within Rv2102at 2363.764 kb on - strand, within Rv2102at 2363.937 kb on + strand, within Rv2102at 2363.937 kb on + strand, within Rv2102at 2364.066 kb on + strandat 2364.067 kb on - strandat 2364.147 kb on + strand, within Rv2103cat 2364.147 kb on + strand, within Rv2103cat 2364.148 kb on - strand, within Rv2103cat 2364.228 kb on + strand, within Rv2103cat 2364.228 kb on + strand, within Rv2103cat 2364.228 kb on + strand, within Rv2103cat 2364.228 kb on + strand, within Rv2103cat 2364.229 kb on - strand, within Rv2103cat 2364.490 kb on - strandat 2364.528 kb on + strandat 2364.529 kb on - strandat 2364.845 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,362,475 + Rv2101 0.73 -1.3
2,362,476 - Rv2101 0.74 -0.6
2,362,476 - Rv2101 0.74 -0.0
2,362,547 + Rv2101 0.76 -0.1
2,362,580 + Rv2101 0.77 -1.2
2,362,581 - Rv2101 0.77 +0.7
2,362,883 + Rv2101 0.87 -0.8
2,363,279 + +0.2
2,363,279 + -0.1
2,363,289 + +0.7
2,363,290 - +0.1
2,363,290 - -0.1
2,363,439 + -0.1
2,363,440 - +0.8
2,363,440 - +0.2
2,363,701 + Rv2102 0.43 +1.2
2,363,763 + Rv2102 0.52 -0.8
2,363,763 + Rv2102 0.52 +1.3
2,363,764 - Rv2102 0.52 -0.2
2,363,937 + Rv2102 0.76 -0.1
2,363,937 + Rv2102 0.76 -0.2
2,364,066 + -0.9
2,364,067 - +0.3
2,364,147 + Rv2103c 0.14 -0.3
2,364,147 + Rv2103c 0.14 +1.7
2,364,148 - Rv2103c 0.14 +0.2
2,364,228 + Rv2103c 0.33 -0.1
2,364,228 + Rv2103c 0.33 -0.7
2,364,228 + Rv2103c 0.33 -0.4
2,364,228 + Rv2103c 0.33 -1.0
2,364,229 - Rv2103c 0.33 -0.3
2,364,490 - -0.1
2,364,528 + +0.0
2,364,529 - -0.3
2,364,845 - -0.4

Or see this region's nucleotide sequence