Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1846c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1844c and Rv1845c are separated by 29 nucleotidesRv1845c and Rv1846c are separated by 14 nucleotidesRv1846c and Rv1847 are separated by 277 nucleotidesRv1847 and Rv1848 are separated by 48 nucleotides Rv1844c: Rv1844c - Probable 6-phosphogluconate dehydrogenase Gnd1, at 2,093,731 to 2,095,188 Rv1844c Rv1845c: Rv1845c - Possible sensor-transducer protein BlaR, at 2,095,218 to 2,096,168 Rv1845c Rv1846c: Rv1846c - Transcriptional repressor BlaI, at 2,096,183 to 2,096,599 Rv1846c Rv1847: Rv1847 - Conserved protein, at 2,096,877 to 2,097,299 Rv1847 Rv1848: Rv1848 - Urease gamma subunit UreA (urea amidohydrolase), at 2,097,348 to 2,097,650 Rv1848 Position (kb) 2096 2097Strain fitness (log2 ratio) -2 -1 0 1at 2096.438 kb on - strand, within Rv1846cat 2096.633 kb on + strandat 2096.643 kb on + strandat 2096.644 kb on - strandat 2096.644 kb on - strandat 2096.644 kb on - strandat 2096.689 kb on + strandat 2096.689 kb on + strandat 2096.689 kb on + strandat 2096.690 kb on - strandat 2096.690 kb on - strandat 2096.690 kb on - strandat 2096.690 kb on - strandat 2096.711 kb on + strandat 2096.712 kb on - strandat 2096.864 kb on + strandat 2096.865 kb on - strandat 2097.040 kb on - strand, within Rv1847at 2097.131 kb on + strand, within Rv1847at 2097.131 kb on + strand, within Rv1847at 2097.131 kb on + strand, within Rv1847at 2097.132 kb on - strand, within Rv1847at 2097.172 kb on - strand, within Rv1847at 2097.172 kb on - strand, within Rv1847at 2097.172 kb on - strand, within Rv1847at 2097.172 kb on - strand, within Rv1847

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,096,438 - Rv1846c 0.61 -0.0
2,096,633 + +0.8
2,096,643 + +0.0
2,096,644 - -0.2
2,096,644 - +0.5
2,096,644 - -0.1
2,096,689 + +0.3
2,096,689 + -2.6
2,096,689 + +0.8
2,096,690 - -1.1
2,096,690 - +0.3
2,096,690 - -0.8
2,096,690 - -0.2
2,096,711 + -0.1
2,096,712 - +0.2
2,096,864 + -0.4
2,096,865 - +0.3
2,097,040 - Rv1847 0.39 -1.2
2,097,131 + Rv1847 0.60 -0.7
2,097,131 + Rv1847 0.60 +0.1
2,097,131 + Rv1847 0.60 +0.3
2,097,132 - Rv1847 0.60 -2.3
2,097,172 - Rv1847 0.70 +0.4
2,097,172 - Rv1847 0.70 -0.3
2,097,172 - Rv1847 0.70 +0.1
2,097,172 - Rv1847 0.70 -0.8

Or see this region's nucleotide sequence