Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0112

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0111 and Rv0112 are separated by 281 nucleotidesRv0112 and Rv0113 are separated by 73 nucleotidesRv0113 and Rv0114 are separated by 31 nucleotides Rv0111: Rv0111 - Possible transmembrane acyltransferase, at 133,950 to 136,007 Rv0111 Rv0112: Rv0112 - Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase), at 136,289 to 137,245 Rv0112 Rv0113: Rv0113 - Probable sedoheptulose-7-phosphate isomerase GmhA (phosphoheptose isomerase), at 137,319 to 137,909 Rv0113 Rv0114: Rv0114 - Possible D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB (D-glycero-D-manno-heptose 7-phosphate kinase), at 137,941 to 138,513 Rv0114 Position (kb) 136 137 138Strain fitness (log2 ratio) -2 -1 0 1 2 3at 135.402 kb on + strand, within Rv0111at 135.483 kb on + strand, within Rv0111at 135.484 kb on - strand, within Rv0111at 135.660 kb on + strand, within Rv0111at 135.661 kb on - strand, within Rv0111at 135.677 kb on - strand, within Rv0111at 135.775 kb on - strand, within Rv0111at 135.894 kb on + strandat 136.089 kb on + strandat 136.090 kb on - strandat 136.101 kb on - strandat 136.159 kb on + strandat 136.163 kb on + strandat 136.164 kb on - strandat 136.164 kb on - strandat 136.375 kb on + strandat 136.376 kb on - strandat 136.622 kb on - strand, within Rv0112at 136.678 kb on + strand, within Rv0112at 136.921 kb on + strand, within Rv0112at 137.043 kb on + strand, within Rv0112at 137.044 kb on - strand, within Rv0112at 137.123 kb on + strand, within Rv0112at 137.151 kb on + strandat 137.588 kb on - strand, within Rv0113at 137.607 kb on + strand, within Rv0113at 138.023 kb on - strand, within Rv0114at 138.100 kb on + strand, within Rv0114at 138.100 kb on + strand, within Rv0114at 138.101 kb on - strand, within Rv0114at 138.170 kb on + strand, within Rv0114at 138.170 kb on + strand, within Rv0114at 138.170 kb on + strand, within Rv0114at 138.215 kb on + strand, within Rv0114at 138.215 kb on + strand, within Rv0114at 138.215 kb on + strand, within Rv0114at 138.216 kb on - strand, within Rv0114

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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135,402 + Rv0111 0.71 +0.9
135,483 + Rv0111 0.74 -0.5
135,484 - Rv0111 0.75 -0.4
135,660 + Rv0111 0.83 -0.9
135,661 - Rv0111 0.83 +1.8
135,677 - Rv0111 0.84 -0.4
135,775 - Rv0111 0.89 -2.0
135,894 + -0.6
136,089 + -0.4
136,090 - -0.8
136,101 - -2.7
136,159 + +0.2
136,163 + +0.1
136,164 - -0.2
136,164 - +3.4
136,375 + -0.1
136,376 - +0.2
136,622 - Rv0112 0.35 +1.0
136,678 + Rv0112 0.41 +0.2
136,921 + Rv0112 0.66 +1.4
137,043 + Rv0112 0.79 +0.3
137,044 - Rv0112 0.79 -0.1
137,123 + Rv0112 0.87 -1.4
137,151 + -0.2
137,588 - Rv0113 0.46 -1.2
137,607 + Rv0113 0.49 -0.2
138,023 - Rv0114 0.14 -0.9
138,100 + Rv0114 0.28 +0.6
138,100 + Rv0114 0.28 -0.4
138,101 - Rv0114 0.28 -0.2
138,170 + Rv0114 0.40 -0.5
138,170 + Rv0114 0.40 -0.3
138,170 + Rv0114 0.40 +0.1
138,215 + Rv0114 0.48 -0.1
138,215 + Rv0114 0.48 -0.4
138,215 + Rv0114 0.48 +0.5
138,216 - Rv0114 0.48 -1.0

Or see this region's nucleotide sequence