Experiment: CDM1 without Cytosine
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt BBR_RS12435 and BBR_RS12440 are separated by 121 nucleotides BBR_RS12440 and BBR_RS20695 are separated by 42 nucleotides BBR_RS20695 and BBR_RS12445 are separated by 433 nucleotides
BBR_RS12435: BBR_RS12435 - ABC transporter ATP-binding protein, at 538,133 to 539,551
_RS12435
BBR_RS12440: BBR_RS12440 - Permease of ABC transporter system, at 539,673 to 541,463
_RS12440
BBR_RS20695: BBR_RS20695 - hypothetical protein, at 541,506 to 541,820
_RS20695
BBR_RS12445: BBR_RS12445 - 50S ribosomal protein L19, at 542,254 to 542,619
_RS12445
Position (kb) 539
540
541
542 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 538.708 kb on + strand, within BBR_RS12435 at 538.738 kb on + strand, within BBR_RS12435 at 538.751 kb on + strand, within BBR_RS12435 at 538.878 kb on - strand, within BBR_RS12435 at 538.878 kb on - strand, within BBR_RS12435 at 538.900 kb on + strand, within BBR_RS12435 at 538.900 kb on + strand, within BBR_RS12435 at 538.900 kb on + strand, within BBR_RS12435 at 538.900 kb on + strand, within BBR_RS12435 at 538.900 kb on + strand, within BBR_RS12435 at 538.906 kb on - strand, within BBR_RS12435 at 538.908 kb on - strand, within BBR_RS12435 at 538.908 kb on - strand, within BBR_RS12435 at 538.908 kb on - strand, within BBR_RS12435 at 538.908 kb on - strand, within BBR_RS12435 at 538.920 kb on - strand, within BBR_RS12435 at 538.937 kb on - strand, within BBR_RS12435 at 538.953 kb on - strand, within BBR_RS12435 at 538.991 kb on + strand, within BBR_RS12435 at 539.020 kb on - strand, within BBR_RS12435 at 539.022 kb on + strand, within BBR_RS12435 at 539.022 kb on + strand, within BBR_RS12435 at 539.022 kb on + strand, within BBR_RS12435 at 539.023 kb on - strand, within BBR_RS12435 at 539.023 kb on - strand, within BBR_RS12435 at 539.030 kb on - strand, within BBR_RS12435 at 539.042 kb on + strand, within BBR_RS12435 at 539.047 kb on + strand, within BBR_RS12435 at 539.064 kb on + strand, within BBR_RS12435 at 539.093 kb on - strand, within BBR_RS12435 at 539.121 kb on - strand, within BBR_RS12435 at 539.191 kb on + strand, within BBR_RS12435 at 539.200 kb on - strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.213 kb on + strand, within BBR_RS12435 at 539.221 kb on - strand, within BBR_RS12435 at 539.221 kb on - strand, within BBR_RS12435 at 539.221 kb on - strand, within BBR_RS12435 at 539.221 kb on - strand, within BBR_RS12435 at 539.221 kb on - strand, within BBR_RS12435 at 539.221 kb on - strand, within BBR_RS12435 at 539.239 kb on + strand, within BBR_RS12435 at 539.254 kb on - strand, within BBR_RS12435 at 539.282 kb on + strand, within BBR_RS12435 at 539.282 kb on + strand, within BBR_RS12435 at 539.290 kb on - strand, within BBR_RS12435 at 539.290 kb on - strand, within BBR_RS12435 at 539.300 kb on + strand, within BBR_RS12435 at 539.327 kb on + strand, within BBR_RS12435 at 539.330 kb on - strand, within BBR_RS12435 at 539.330 kb on - strand, within BBR_RS12435 at 539.330 kb on - strand, within BBR_RS12435 at 539.330 kb on - strand, within BBR_RS12435 at 539.331 kb on + strand, within BBR_RS12435 at 539.336 kb on + strand, within BBR_RS12435 at 539.339 kb on - strand, within BBR_RS12435 at 539.339 kb on - strand, within BBR_RS12435 at 539.412 kb on - strand at 539.477 kb on - strand at 539.485 kb on - strand at 539.508 kb on + strand at 539.545 kb on + strand at 539.554 kb on - strand at 539.555 kb on - strand at 539.561 kb on - strand at 539.566 kb on - strand at 539.619 kb on + strand at 539.624 kb on + strand at 539.626 kb on - strand at 539.647 kb on + strand at 539.650 kb on + strand at 539.655 kb on - strand at 539.660 kb on + strand at 539.671 kb on + strand at 539.689 kb on - strand at 539.696 kb on + strand at 539.696 kb on + strand at 539.709 kb on - strand at 539.783 kb on - strand at 539.785 kb on + strand at 539.833 kb on - strand at 539.849 kb on + strand at 539.857 kb on - strand, within BBR_RS12440 at 539.873 kb on + strand, within BBR_RS12440 at 539.911 kb on - strand, within BBR_RS12440 at 539.911 kb on - strand, within BBR_RS12440 at 539.959 kb on - strand, within BBR_RS12440 at 539.986 kb on - strand, within BBR_RS12440 at 540.045 kb on - strand, within BBR_RS12440 at 540.047 kb on + strand, within BBR_RS12440 at 540.049 kb on + strand, within BBR_RS12440 at 540.049 kb on + strand, within BBR_RS12440 at 540.051 kb on + strand, within BBR_RS12440 at 540.055 kb on - strand, within BBR_RS12440 at 540.055 kb on - strand, within BBR_RS12440 at 540.055 kb on - strand, within BBR_RS12440 at 540.055 kb on - strand, within BBR_RS12440 at 540.059 kb on - strand, within BBR_RS12440 at 540.059 kb on - strand, within BBR_RS12440 at 540.075 kb on + strand, within BBR_RS12440 at 540.106 kb on + strand, within BBR_RS12440 at 540.118 kb on + strand, within BBR_RS12440 at 540.121 kb on - strand, within BBR_RS12440 at 540.121 kb on - strand, within BBR_RS12440 at 540.125 kb on + strand, within BBR_RS12440 at 540.141 kb on + strand, within BBR_RS12440 at 540.170 kb on - strand, within BBR_RS12440 at 540.216 kb on + strand, within BBR_RS12440 at 540.269 kb on - strand, within BBR_RS12440 at 540.279 kb on - strand, within BBR_RS12440 at 540.279 kb on - strand, within BBR_RS12440 at 540.290 kb on - strand, within BBR_RS12440 at 540.299 kb on - strand, within BBR_RS12440 at 540.304 kb on + strand, within BBR_RS12440 at 540.307 kb on + strand, within BBR_RS12440 at 540.307 kb on + strand, within BBR_RS12440 at 540.341 kb on + strand, within BBR_RS12440 at 540.412 kb on - strand, within BBR_RS12440 at 540.443 kb on - strand, within BBR_RS12440 at 540.450 kb on - strand, within BBR_RS12440 at 540.473 kb on + strand, within BBR_RS12440 at 540.477 kb on - strand, within BBR_RS12440 at 540.491 kb on - strand, within BBR_RS12440 at 540.510 kb on - strand, within BBR_RS12440 at 540.532 kb on + strand, within BBR_RS12440 at 540.536 kb on - strand, within BBR_RS12440 at 540.547 kb on + strand, within BBR_RS12440 at 540.562 kb on + strand, within BBR_RS12440 at 540.565 kb on - strand, within BBR_RS12440 at 540.565 kb on - strand, within BBR_RS12440 at 540.570 kb on + strand, within BBR_RS12440 at 540.575 kb on - strand, within BBR_RS12440 at 540.575 kb on - strand, within BBR_RS12440 at 540.596 kb on - strand, within BBR_RS12440 at 540.631 kb on + strand, within BBR_RS12440 at 540.654 kb on - strand, within BBR_RS12440 at 540.654 kb on - strand, within BBR_RS12440 at 540.654 kb on - strand, within BBR_RS12440 at 540.677 kb on + strand, within BBR_RS12440 at 540.725 kb on + strand, within BBR_RS12440 at 540.747 kb on - strand, within BBR_RS12440 at 540.749 kb on + strand, within BBR_RS12440 at 540.749 kb on + strand, within BBR_RS12440 at 540.749 kb on + strand, within BBR_RS12440 at 540.752 kb on - strand, within BBR_RS12440 at 540.757 kb on - strand, within BBR_RS12440 at 540.794 kb on + strand, within BBR_RS12440 at 540.804 kb on + strand, within BBR_RS12440 at 540.804 kb on + strand, within BBR_RS12440 at 540.804 kb on + strand, within BBR_RS12440 at 540.836 kb on - strand, within BBR_RS12440 at 540.846 kb on - strand, within BBR_RS12440 at 540.876 kb on - strand, within BBR_RS12440 at 540.887 kb on + strand, within BBR_RS12440 at 540.887 kb on + strand, within BBR_RS12440 at 540.887 kb on + strand, within BBR_RS12440 at 540.893 kb on + strand, within BBR_RS12440 at 540.893 kb on + strand, within BBR_RS12440 at 540.893 kb on + strand, within BBR_RS12440 at 540.895 kb on - strand, within BBR_RS12440 at 540.901 kb on - strand, within BBR_RS12440 at 540.901 kb on - strand, within BBR_RS12440 at 540.901 kb on - strand, within BBR_RS12440 at 540.910 kb on + strand, within BBR_RS12440 at 540.929 kb on + strand, within BBR_RS12440 at 540.937 kb on - strand, within BBR_RS12440 at 540.945 kb on - strand, within BBR_RS12440 at 540.949 kb on - strand, within BBR_RS12440 at 540.960 kb on + strand, within BBR_RS12440 at 541.019 kb on + strand, within BBR_RS12440 at 541.025 kb on - strand, within BBR_RS12440 at 541.027 kb on - strand, within BBR_RS12440 at 541.097 kb on - strand, within BBR_RS12440 at 541.137 kb on - strand, within BBR_RS12440 at 541.152 kb on + strand, within BBR_RS12440 at 541.162 kb on + strand, within BBR_RS12440 at 541.172 kb on - strand, within BBR_RS12440 at 541.200 kb on + strand, within BBR_RS12440 at 541.219 kb on + strand, within BBR_RS12440 at 541.241 kb on + strand, within BBR_RS12440 at 541.249 kb on - strand, within BBR_RS12440 at 541.260 kb on + strand, within BBR_RS12440 at 541.268 kb on - strand, within BBR_RS12440 at 541.268 kb on - strand, within BBR_RS12440 at 541.283 kb on + strand, within BBR_RS12440 at 541.347 kb on - strand at 541.364 kb on + strand at 541.371 kb on + strand at 541.379 kb on + strand at 541.383 kb on + strand at 541.396 kb on - strand at 541.430 kb on - strand at 541.430 kb on - strand at 541.470 kb on + strand at 541.570 kb on - strand, within BBR_RS20695 at 541.661 kb on + strand, within BBR_RS20695 at 541.689 kb on + strand, within BBR_RS20695 at 541.710 kb on + strand, within BBR_RS20695 at 541.711 kb on - strand, within BBR_RS20695 at 541.783 kb on + strand, within BBR_RS20695 at 541.847 kb on - strand at 541.864 kb on + strand at 541.888 kb on + strand at 541.889 kb on + strand at 541.930 kb on + strand at 541.932 kb on - strand at 541.941 kb on + strand at 541.941 kb on + strand at 541.948 kb on + strand at 541.968 kb on + strand at 542.011 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction CDM1 without Cytosine remove 538,708 + BBR_RS12435 0.41 +0.4 538,738 + BBR_RS12435 0.43 +1.3 538,751 + BBR_RS12435 0.44 +0.4 538,878 - BBR_RS12435 0.53 +0.8 538,878 - BBR_RS12435 0.53 +0.6 538,900 + BBR_RS12435 0.54 +0.4 538,900 + BBR_RS12435 0.54 -0.9 538,900 + BBR_RS12435 0.54 -0.3 538,900 + BBR_RS12435 0.54 +0.0 538,900 + BBR_RS12435 0.54 -1.9 538,906 - BBR_RS12435 0.54 +0.8 538,908 - BBR_RS12435 0.55 -1.0 538,908 - BBR_RS12435 0.55 +0.2 538,908 - BBR_RS12435 0.55 +1.7 538,908 - BBR_RS12435 0.55 -1.3 538,920 - BBR_RS12435 0.55 +0.1 538,937 - BBR_RS12435 0.57 -2.3 538,953 - BBR_RS12435 0.58 -0.3 538,991 + BBR_RS12435 0.60 -1.2 539,020 - BBR_RS12435 0.63 -0.6 539,022 + BBR_RS12435 0.63 +0.6 539,022 + BBR_RS12435 0.63 -0.9 539,022 + BBR_RS12435 0.63 +0.2 539,023 - BBR_RS12435 0.63 +0.1 539,023 - BBR_RS12435 0.63 -0.3 539,030 - BBR_RS12435 0.63 +0.0 539,042 + BBR_RS12435 0.64 +0.8 539,047 + BBR_RS12435 0.64 -1.1 539,064 + BBR_RS12435 0.66 -0.6 539,093 - BBR_RS12435 0.68 -0.2 539,121 - BBR_RS12435 0.70 +1.3 539,191 + BBR_RS12435 0.75 +1.8 539,200 - BBR_RS12435 0.75 -0.1 539,213 + BBR_RS12435 0.76 +0.4 539,213 + BBR_RS12435 0.76 +0.8 539,213 + BBR_RS12435 0.76 +0.5 539,213 + BBR_RS12435 0.76 -0.1 539,213 + BBR_RS12435 0.76 -1.1 539,213 + BBR_RS12435 0.76 +1.1 539,213 + BBR_RS12435 0.76 +0.5 539,213 + BBR_RS12435 0.76 +0.4 539,213 + BBR_RS12435 0.76 +1.1 539,221 - BBR_RS12435 0.77 +1.9 539,221 - BBR_RS12435 0.77 -0.0 539,221 - BBR_RS12435 0.77 -0.1 539,221 - BBR_RS12435 0.77 +1.3 539,221 - BBR_RS12435 0.77 +1.7 539,221 - BBR_RS12435 0.77 +0.4 539,239 + BBR_RS12435 0.78 -0.9 539,254 - BBR_RS12435 0.79 -1.0 539,282 + BBR_RS12435 0.81 +0.4 539,282 + BBR_RS12435 0.81 -1.4 539,290 - BBR_RS12435 0.82 +0.1 539,290 - BBR_RS12435 0.82 -1.4 539,300 + BBR_RS12435 0.82 -1.2 539,327 + BBR_RS12435 0.84 +0.1 539,330 - BBR_RS12435 0.84 +0.7 539,330 - BBR_RS12435 0.84 -1.2 539,330 - BBR_RS12435 0.84 +1.4 539,330 - BBR_RS12435 0.84 -1.0 539,331 + BBR_RS12435 0.84 +0.4 539,336 + BBR_RS12435 0.85 -1.4 539,339 - BBR_RS12435 0.85 -1.5 539,339 - BBR_RS12435 0.85 +1.0 539,412 - +0.0 539,477 - -0.0 539,485 - +1.0 539,508 + +1.0 539,545 + -0.7 539,554 - +0.1 539,555 - -0.5 539,561 - -1.3 539,566 - -0.5 539,619 + -0.6 539,624 + -0.3 539,626 - +0.5 539,647 + -0.7 539,650 + -0.4 539,655 - -0.4 539,660 + -0.5 539,671 + -1.3 539,689 - -0.5 539,696 + -1.3 539,696 + -1.3 539,709 - -0.8 539,783 - -0.6 539,785 + +0.4 539,833 - -0.8 539,849 + -0.8 539,857 - BBR_RS12440 0.10 -1.7 539,873 + BBR_RS12440 0.11 -0.4 539,911 - BBR_RS12440 0.13 +0.4 539,911 - BBR_RS12440 0.13 +0.0 539,959 - BBR_RS12440 0.16 -2.4 539,986 - BBR_RS12440 0.17 -1.6 540,045 - BBR_RS12440 0.21 -0.4 540,047 + BBR_RS12440 0.21 +0.0 540,049 + BBR_RS12440 0.21 -0.4 540,049 + BBR_RS12440 0.21 -1.5 540,051 + BBR_RS12440 0.21 +0.2 540,055 - BBR_RS12440 0.21 -0.5 540,055 - BBR_RS12440 0.21 -0.5 540,055 - BBR_RS12440 0.21 +0.7 540,055 - BBR_RS12440 0.21 -1.2 540,059 - BBR_RS12440 0.22 +0.1 540,059 - BBR_RS12440 0.22 -2.5 540,075 + BBR_RS12440 0.22 -0.8 540,106 + BBR_RS12440 0.24 +0.1 540,118 + BBR_RS12440 0.25 +0.0 540,121 - BBR_RS12440 0.25 -1.2 540,121 - BBR_RS12440 0.25 -0.7 540,125 + BBR_RS12440 0.25 +0.3 540,141 + BBR_RS12440 0.26 -0.2 540,170 - BBR_RS12440 0.28 -0.3 540,216 + BBR_RS12440 0.30 -0.5 540,269 - BBR_RS12440 0.33 -1.4 540,279 - BBR_RS12440 0.34 -0.8 540,279 - BBR_RS12440 0.34 -3.1 540,290 - BBR_RS12440 0.34 +0.4 540,299 - BBR_RS12440 0.35 -0.2 540,304 + BBR_RS12440 0.35 +0.4 540,307 + BBR_RS12440 0.35 +0.2 540,307 + BBR_RS12440 0.35 +0.6 540,341 + BBR_RS12440 0.37 +0.3 540,412 - BBR_RS12440 0.41 -1.0 540,443 - BBR_RS12440 0.43 +0.2 540,450 - BBR_RS12440 0.43 -0.3 540,473 + BBR_RS12440 0.45 -1.2 540,477 - BBR_RS12440 0.45 -2.8 540,491 - BBR_RS12440 0.46 +1.2 540,510 - BBR_RS12440 0.47 -0.6 540,532 + BBR_RS12440 0.48 +0.8 540,536 - BBR_RS12440 0.48 -0.7 540,547 + BBR_RS12440 0.49 -0.3 540,562 + BBR_RS12440 0.50 -1.7 540,565 - BBR_RS12440 0.50 -1.8 540,565 - BBR_RS12440 0.50 -0.7 540,570 + BBR_RS12440 0.50 +0.6 540,575 - BBR_RS12440 0.50 -2.1 540,575 - BBR_RS12440 0.50 +0.8 540,596 - BBR_RS12440 0.52 -1.0 540,631 + BBR_RS12440 0.53 +0.3 540,654 - BBR_RS12440 0.55 -1.1 540,654 - BBR_RS12440 0.55 -1.1 540,654 - BBR_RS12440 0.55 -0.3 540,677 + BBR_RS12440 0.56 +0.0 540,725 + BBR_RS12440 0.59 -2.0 540,747 - BBR_RS12440 0.60 -0.2 540,749 + BBR_RS12440 0.60 -0.3 540,749 + BBR_RS12440 0.60 -3.1 540,749 + BBR_RS12440 0.60 +0.0 540,752 - BBR_RS12440 0.60 -0.6 540,757 - BBR_RS12440 0.61 -0.6 540,794 + BBR_RS12440 0.63 -0.1 540,804 + BBR_RS12440 0.63 +0.2 540,804 + BBR_RS12440 0.63 -0.0 540,804 + BBR_RS12440 0.63 +0.6 540,836 - BBR_RS12440 0.65 +1.0 540,846 - BBR_RS12440 0.65 -0.1 540,876 - BBR_RS12440 0.67 -1.1 540,887 + BBR_RS12440 0.68 +0.4 540,887 + BBR_RS12440 0.68 +0.3 540,887 + BBR_RS12440 0.68 +1.3 540,893 + BBR_RS12440 0.68 -0.1 540,893 + BBR_RS12440 0.68 -1.3 540,893 + BBR_RS12440 0.68 -2.5 540,895 - BBR_RS12440 0.68 -3.3 540,901 - BBR_RS12440 0.69 +3.2 540,901 - BBR_RS12440 0.69 -3.4 540,901 - BBR_RS12440 0.69 -0.9 540,910 + BBR_RS12440 0.69 -2.7 540,929 + BBR_RS12440 0.70 -2.4 540,937 - BBR_RS12440 0.71 +0.6 540,945 - BBR_RS12440 0.71 -1.8 540,949 - BBR_RS12440 0.71 -3.9 540,960 + BBR_RS12440 0.72 -0.6 541,019 + BBR_RS12440 0.75 -3.6 541,025 - BBR_RS12440 0.75 +1.0 541,027 - BBR_RS12440 0.76 -0.1 541,097 - BBR_RS12440 0.80 -0.9 541,137 - BBR_RS12440 0.82 -0.8 541,152 + BBR_RS12440 0.83 -0.5 541,162 + BBR_RS12440 0.83 -2.9 541,172 - BBR_RS12440 0.84 +0.1 541,200 + BBR_RS12440 0.85 -1.6 541,219 + BBR_RS12440 0.86 -0.8 541,241 + BBR_RS12440 0.88 -1.7 541,249 - BBR_RS12440 0.88 -1.5 541,260 + BBR_RS12440 0.89 -0.3 541,268 - BBR_RS12440 0.89 -1.1 541,268 - BBR_RS12440 0.89 -1.2 541,283 + BBR_RS12440 0.90 -3.4 541,347 - -1.7 541,364 + -0.1 541,371 + +0.2 541,379 + -1.5 541,383 + -1.4 541,396 - -0.3 541,430 - -1.1 541,430 - -2.2 541,470 + -0.8 541,570 - BBR_RS20695 0.20 -1.1 541,661 + BBR_RS20695 0.49 +0.6 541,689 + BBR_RS20695 0.58 +0.6 541,710 + BBR_RS20695 0.65 +0.5 541,711 - BBR_RS20695 0.65 -0.7 541,783 + BBR_RS20695 0.88 -0.2 541,847 - -1.6 541,864 + -2.9 541,888 + +2.0 541,889 + -1.0 541,930 + -0.3 541,932 - -1.3 541,941 + +0.8 541,941 + +0.1 541,948 + -0.0 541,968 + +0.9 542,011 - -2.5
Or see this region's nucleotide sequence