Experiment: CDM1 without Serine
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt BBR_RS12870 and BBR_RS12875 are separated by 51 nucleotides BBR_RS12875 and BBR_RS12880 are separated by 111 nucleotides BBR_RS12880 and BBR_RS12885 are separated by 128 nucleotides
BBR_RS12870: BBR_RS12870 - 3-isopropylmalate dehydrogenase, at 637,861 to 638,892
_RS12870
BBR_RS12875: BBR_RS12875 - lipoate--protein ligase A, at 638,944 to 640,107
_RS12875
BBR_RS12880: BBR_RS12880 - Crp/Fnr family transcriptional regulator, at 640,219 to 640,938
_RS12880
BBR_RS12885: BBR_RS12885 - penicillin-binding protein, at 641,067 to 643,337
_RS12885
Position (kb)
638
639
640
641 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1
2
3 at 637.951 kb on + strand at 637.975 kb on + strand, within BBR_RS12870 at 637.981 kb on - strand, within BBR_RS12870 at 638.049 kb on + strand, within BBR_RS12870 at 638.068 kb on + strand, within BBR_RS12870 at 638.068 kb on + strand, within BBR_RS12870 at 638.073 kb on + strand, within BBR_RS12870 at 638.073 kb on + strand, within BBR_RS12870 at 638.073 kb on + strand, within BBR_RS12870 at 638.080 kb on + strand, within BBR_RS12870 at 638.081 kb on - strand, within BBR_RS12870 at 638.147 kb on + strand, within BBR_RS12870 at 638.147 kb on + strand, within BBR_RS12870 at 638.147 kb on + strand, within BBR_RS12870 at 638.147 kb on + strand, within BBR_RS12870 at 638.147 kb on + strand, within BBR_RS12870 at 638.155 kb on - strand, within BBR_RS12870 at 638.155 kb on - strand, within BBR_RS12870 at 638.155 kb on - strand, within BBR_RS12870 at 638.155 kb on - strand, within BBR_RS12870 at 638.159 kb on + strand, within BBR_RS12870 at 638.192 kb on - strand, within BBR_RS12870 at 638.199 kb on - strand, within BBR_RS12870 at 638.222 kb on - strand, within BBR_RS12870 at 638.231 kb on + strand, within BBR_RS12870 at 638.231 kb on + strand, within BBR_RS12870 at 638.239 kb on - strand, within BBR_RS12870 at 638.257 kb on + strand, within BBR_RS12870 at 638.257 kb on + strand, within BBR_RS12870 at 638.262 kb on + strand, within BBR_RS12870 at 638.262 kb on + strand, within BBR_RS12870 at 638.262 kb on + strand, within BBR_RS12870 at 638.262 kb on + strand, within BBR_RS12870 at 638.265 kb on - strand, within BBR_RS12870 at 638.265 kb on - strand, within BBR_RS12870 at 638.270 kb on - strand, within BBR_RS12870 at 638.282 kb on - strand, within BBR_RS12870 at 638.282 kb on - strand, within BBR_RS12870 at 638.287 kb on - strand, within BBR_RS12870 at 638.287 kb on - strand, within BBR_RS12870 at 638.289 kb on + strand, within BBR_RS12870 at 638.297 kb on + strand, within BBR_RS12870 at 638.299 kb on + strand, within BBR_RS12870 at 638.299 kb on + strand, within BBR_RS12870 at 638.325 kb on + strand, within BBR_RS12870 at 638.330 kb on + strand, within BBR_RS12870 at 638.341 kb on + strand, within BBR_RS12870 at 638.349 kb on - strand, within BBR_RS12870 at 638.366 kb on + strand, within BBR_RS12870 at 638.374 kb on - strand, within BBR_RS12870 at 638.377 kb on + strand, within BBR_RS12870 at 638.377 kb on + strand, within BBR_RS12870 at 638.401 kb on + strand, within BBR_RS12870 at 638.404 kb on - strand, within BBR_RS12870 at 638.407 kb on - strand, within BBR_RS12870 at 638.425 kb on + strand, within BBR_RS12870 at 638.435 kb on - strand, within BBR_RS12870 at 638.451 kb on - strand, within BBR_RS12870 at 638.542 kb on - strand, within BBR_RS12870 at 638.557 kb on - strand, within BBR_RS12870 at 638.582 kb on + strand, within BBR_RS12870 at 638.703 kb on + strand, within BBR_RS12870 at 638.713 kb on + strand, within BBR_RS12870 at 638.713 kb on + strand, within BBR_RS12870 at 638.718 kb on + strand, within BBR_RS12870 at 638.718 kb on + strand, within BBR_RS12870 at 638.718 kb on + strand, within BBR_RS12870 at 638.718 kb on + strand, within BBR_RS12870 at 638.726 kb on - strand, within BBR_RS12870 at 638.726 kb on - strand, within BBR_RS12870 at 638.733 kb on + strand, within BBR_RS12870 at 638.770 kb on - strand, within BBR_RS12870 at 638.770 kb on - strand, within BBR_RS12870 at 638.831 kb on - strand at 638.843 kb on - strand at 638.845 kb on - strand at 638.845 kb on - strand at 638.855 kb on - strand at 638.855 kb on - strand at 638.860 kb on - strand at 638.884 kb on + strand at 638.886 kb on + strand at 638.894 kb on - strand at 638.894 kb on - strand at 638.896 kb on + strand at 638.896 kb on + strand at 638.904 kb on - strand at 638.913 kb on - strand at 638.928 kb on + strand at 638.928 kb on + strand at 638.928 kb on + strand at 638.928 kb on + strand at 638.928 kb on + strand at 638.928 kb on + strand at 638.936 kb on - strand at 638.936 kb on - strand at 638.936 kb on - strand at 638.938 kb on - strand at 639.062 kb on + strand, within BBR_RS12875 at 639.062 kb on + strand, within BBR_RS12875 at 639.062 kb on + strand, within BBR_RS12875 at 639.148 kb on - strand, within BBR_RS12875 at 639.222 kb on + strand, within BBR_RS12875 at 639.241 kb on + strand, within BBR_RS12875 at 639.253 kb on + strand, within BBR_RS12875 at 639.253 kb on + strand, within BBR_RS12875 at 639.266 kb on + strand, within BBR_RS12875 at 639.290 kb on - strand, within BBR_RS12875 at 639.302 kb on + strand, within BBR_RS12875 at 639.303 kb on + strand, within BBR_RS12875 at 639.312 kb on + strand, within BBR_RS12875 at 639.320 kb on - strand, within BBR_RS12875 at 639.320 kb on - strand, within BBR_RS12875 at 639.410 kb on + strand, within BBR_RS12875 at 639.454 kb on - strand, within BBR_RS12875 at 639.504 kb on - strand, within BBR_RS12875 at 639.533 kb on + strand, within BBR_RS12875 at 639.571 kb on + strand, within BBR_RS12875 at 639.571 kb on + strand, within BBR_RS12875 at 639.579 kb on - strand, within BBR_RS12875 at 639.579 kb on - strand, within BBR_RS12875 at 639.579 kb on - strand, within BBR_RS12875 at 639.581 kb on + strand, within BBR_RS12875 at 639.593 kb on - strand, within BBR_RS12875 at 639.606 kb on + strand, within BBR_RS12875 at 639.629 kb on - strand, within BBR_RS12875 at 639.630 kb on - strand, within BBR_RS12875 at 639.635 kb on - strand, within BBR_RS12875 at 639.651 kb on - strand, within BBR_RS12875 at 639.663 kb on + strand, within BBR_RS12875 at 639.671 kb on - strand, within BBR_RS12875 at 639.677 kb on + strand, within BBR_RS12875 at 639.677 kb on + strand, within BBR_RS12875 at 639.677 kb on + strand, within BBR_RS12875 at 639.678 kb on - strand, within BBR_RS12875 at 639.678 kb on - strand, within BBR_RS12875 at 639.685 kb on - strand, within BBR_RS12875 at 639.720 kb on - strand, within BBR_RS12875 at 639.722 kb on - strand, within BBR_RS12875 at 639.731 kb on + strand, within BBR_RS12875 at 639.756 kb on + strand, within BBR_RS12875 at 639.756 kb on + strand, within BBR_RS12875 at 639.756 kb on + strand, within BBR_RS12875 at 639.757 kb on + strand, within BBR_RS12875 at 639.773 kb on + strand, within BBR_RS12875 at 639.773 kb on + strand, within BBR_RS12875 at 639.779 kb on + strand, within BBR_RS12875 at 639.787 kb on - strand, within BBR_RS12875 at 639.804 kb on + strand, within BBR_RS12875 at 639.858 kb on + strand, within BBR_RS12875 at 639.882 kb on + strand, within BBR_RS12875 at 639.890 kb on - strand, within BBR_RS12875 at 639.892 kb on + strand, within BBR_RS12875 at 639.892 kb on + strand, within BBR_RS12875 at 639.894 kb on + strand, within BBR_RS12875 at 639.900 kb on - strand, within BBR_RS12875 at 639.943 kb on + strand, within BBR_RS12875 at 639.956 kb on - strand, within BBR_RS12875 at 639.975 kb on + strand, within BBR_RS12875 at 640.029 kb on - strand at 640.065 kb on - strand at 640.065 kb on - strand at 640.071 kb on + strand at 640.079 kb on - strand at 640.079 kb on - strand at 640.079 kb on - strand at 640.079 kb on - strand at 640.079 kb on - strand at 640.125 kb on - strand at 640.204 kb on + strand at 640.204 kb on + strand at 640.204 kb on + strand at 640.204 kb on + strand at 640.209 kb on + strand at 640.212 kb on - strand at 640.212 kb on - strand at 640.212 kb on - strand at 640.224 kb on - strand at 640.269 kb on + strand at 640.271 kb on + strand at 640.281 kb on + strand at 640.281 kb on + strand at 640.289 kb on - strand at 640.327 kb on - strand, within BBR_RS12880 at 640.379 kb on - strand, within BBR_RS12880 at 640.394 kb on + strand, within BBR_RS12880 at 640.398 kb on - strand, within BBR_RS12880 at 640.413 kb on + strand, within BBR_RS12880 at 640.421 kb on - strand, within BBR_RS12880 at 640.463 kb on + strand, within BBR_RS12880 at 640.483 kb on - strand, within BBR_RS12880 at 640.527 kb on + strand, within BBR_RS12880 at 640.563 kb on + strand, within BBR_RS12880 at 640.585 kb on + strand, within BBR_RS12880 at 640.622 kb on + strand, within BBR_RS12880 at 640.622 kb on + strand, within BBR_RS12880 at 640.635 kb on + strand, within BBR_RS12880 at 640.643 kb on - strand, within BBR_RS12880 at 640.673 kb on + strand, within BBR_RS12880 at 640.678 kb on + strand, within BBR_RS12880 at 640.686 kb on + strand, within BBR_RS12880 at 640.696 kb on - strand, within BBR_RS12880 at 640.710 kb on + strand, within BBR_RS12880 at 640.717 kb on + strand, within BBR_RS12880 at 640.718 kb on - strand, within BBR_RS12880 at 640.722 kb on + strand, within BBR_RS12880 at 640.747 kb on - strand, within BBR_RS12880 at 640.761 kb on - strand, within BBR_RS12880 at 640.787 kb on + strand, within BBR_RS12880 at 640.787 kb on + strand, within BBR_RS12880 at 640.808 kb on - strand, within BBR_RS12880 at 640.809 kb on + strand, within BBR_RS12880 at 640.828 kb on + strand, within BBR_RS12880 at 640.882 kb on - strand at 640.940 kb on - strand at 640.988 kb on + strand at 640.996 kb on - strand at 641.038 kb on - strand at 641.050 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction CDM1 without Serine remove 637,951 + +0.9 637,975 + BBR_RS12870 0.11 +1.1 637,981 - BBR_RS12870 0.12 +0.0 638,049 + BBR_RS12870 0.18 +0.9 638,068 + BBR_RS12870 0.20 +1.0 638,068 + BBR_RS12870 0.20 +0.9 638,073 + BBR_RS12870 0.21 +1.3 638,073 + BBR_RS12870 0.21 +1.9 638,073 + BBR_RS12870 0.21 +1.8 638,080 + BBR_RS12870 0.21 +1.3 638,081 - BBR_RS12870 0.21 -0.2 638,147 + BBR_RS12870 0.28 +2.6 638,147 + BBR_RS12870 0.28 +1.5 638,147 + BBR_RS12870 0.28 +1.3 638,147 + BBR_RS12870 0.28 +3.0 638,147 + BBR_RS12870 0.28 +2.7 638,155 - BBR_RS12870 0.28 -0.1 638,155 - BBR_RS12870 0.28 +0.4 638,155 - BBR_RS12870 0.28 +1.0 638,155 - BBR_RS12870 0.28 +0.1 638,159 + BBR_RS12870 0.29 +0.3 638,192 - BBR_RS12870 0.32 +2.1 638,199 - BBR_RS12870 0.33 +1.6 638,222 - BBR_RS12870 0.35 +0.4 638,231 + BBR_RS12870 0.36 +0.5 638,231 + BBR_RS12870 0.36 +1.3 638,239 - BBR_RS12870 0.37 +1.8 638,257 + BBR_RS12870 0.38 +2.2 638,257 + BBR_RS12870 0.38 +1.2 638,262 + BBR_RS12870 0.39 +1.6 638,262 + BBR_RS12870 0.39 +2.1 638,262 + BBR_RS12870 0.39 +0.8 638,262 + BBR_RS12870 0.39 +2.7 638,265 - BBR_RS12870 0.39 +0.5 638,265 - BBR_RS12870 0.39 +0.9 638,270 - BBR_RS12870 0.40 +0.6 638,282 - BBR_RS12870 0.41 +0.3 638,282 - BBR_RS12870 0.41 +1.4 638,287 - BBR_RS12870 0.41 +0.9 638,287 - BBR_RS12870 0.41 +1.3 638,289 + BBR_RS12870 0.41 +0.2 638,297 + BBR_RS12870 0.42 +1.3 638,299 + BBR_RS12870 0.42 +1.5 638,299 + BBR_RS12870 0.42 +2.0 638,325 + BBR_RS12870 0.45 +0.2 638,330 + BBR_RS12870 0.45 -0.2 638,341 + BBR_RS12870 0.47 +0.6 638,349 - BBR_RS12870 0.47 +0.8 638,366 + BBR_RS12870 0.49 +1.4 638,374 - BBR_RS12870 0.50 +0.4 638,377 + BBR_RS12870 0.50 +1.1 638,377 + BBR_RS12870 0.50 +1.2 638,401 + BBR_RS12870 0.52 +0.8 638,404 - BBR_RS12870 0.53 +0.8 638,407 - BBR_RS12870 0.53 +2.2 638,425 + BBR_RS12870 0.55 +2.4 638,435 - BBR_RS12870 0.56 -1.7 638,451 - BBR_RS12870 0.57 +0.3 638,542 - BBR_RS12870 0.66 +2.3 638,557 - BBR_RS12870 0.67 -0.0 638,582 + BBR_RS12870 0.70 +2.3 638,703 + BBR_RS12870 0.82 +1.0 638,713 + BBR_RS12870 0.83 +0.7 638,713 + BBR_RS12870 0.83 +1.5 638,718 + BBR_RS12870 0.83 +0.9 638,718 + BBR_RS12870 0.83 +1.9 638,718 + BBR_RS12870 0.83 +2.1 638,718 + BBR_RS12870 0.83 +1.3 638,726 - BBR_RS12870 0.84 +0.0 638,726 - BBR_RS12870 0.84 +1.1 638,733 + BBR_RS12870 0.84 +2.1 638,770 - BBR_RS12870 0.88 +1.7 638,770 - BBR_RS12870 0.88 -0.3 638,831 - +2.2 638,843 - +1.4 638,845 - -0.7 638,845 - -2.0 638,855 - +0.1 638,855 - -0.8 638,860 - +0.9 638,884 + +0.1 638,886 + +0.4 638,894 - -2.2 638,894 - -1.0 638,896 + +0.7 638,896 + +1.0 638,904 - +1.0 638,913 - +0.8 638,928 + -0.3 638,928 + +0.5 638,928 + -0.3 638,928 + -0.0 638,928 + -0.3 638,928 + -0.3 638,936 - +0.1 638,936 - +1.0 638,936 - -0.6 638,938 - -1.6 639,062 + BBR_RS12875 0.10 -0.4 639,062 + BBR_RS12875 0.10 -0.4 639,062 + BBR_RS12875 0.10 -1.2 639,148 - BBR_RS12875 0.18 -0.1 639,222 + BBR_RS12875 0.24 +0.6 639,241 + BBR_RS12875 0.26 -0.8 639,253 + BBR_RS12875 0.27 +0.6 639,253 + BBR_RS12875 0.27 -1.1 639,266 + BBR_RS12875 0.28 -0.3 639,290 - BBR_RS12875 0.30 -0.4 639,302 + BBR_RS12875 0.31 -0.5 639,303 + BBR_RS12875 0.31 +0.6 639,312 + BBR_RS12875 0.32 -0.1 639,320 - BBR_RS12875 0.32 +0.1 639,320 - BBR_RS12875 0.32 -0.3 639,410 + BBR_RS12875 0.40 +0.2 639,454 - BBR_RS12875 0.44 +0.5 639,504 - BBR_RS12875 0.48 -0.9 639,533 + BBR_RS12875 0.51 +1.1 639,571 + BBR_RS12875 0.54 +0.2 639,571 + BBR_RS12875 0.54 +0.1 639,579 - BBR_RS12875 0.55 +1.2 639,579 - BBR_RS12875 0.55 +1.1 639,579 - BBR_RS12875 0.55 -0.6 639,581 + BBR_RS12875 0.55 -4.8 639,593 - BBR_RS12875 0.56 +0.4 639,606 + BBR_RS12875 0.57 -0.6 639,629 - BBR_RS12875 0.59 -0.1 639,630 - BBR_RS12875 0.59 -1.4 639,635 - BBR_RS12875 0.59 -1.3 639,651 - BBR_RS12875 0.61 -0.3 639,663 + BBR_RS12875 0.62 +0.1 639,671 - BBR_RS12875 0.62 +0.5 639,677 + BBR_RS12875 0.63 +0.7 639,677 + BBR_RS12875 0.63 +0.2 639,677 + BBR_RS12875 0.63 +0.1 639,678 - BBR_RS12875 0.63 +1.0 639,678 - BBR_RS12875 0.63 -1.0 639,685 - BBR_RS12875 0.64 -0.2 639,720 - BBR_RS12875 0.67 -0.0 639,722 - BBR_RS12875 0.67 +0.2 639,731 + BBR_RS12875 0.68 -0.3 639,756 + BBR_RS12875 0.70 -0.1 639,756 + BBR_RS12875 0.70 +0.5 639,756 + BBR_RS12875 0.70 -0.7 639,757 + BBR_RS12875 0.70 -0.7 639,773 + BBR_RS12875 0.71 +0.2 639,773 + BBR_RS12875 0.71 -1.2 639,779 + BBR_RS12875 0.72 -0.9 639,787 - BBR_RS12875 0.72 -0.7 639,804 + BBR_RS12875 0.74 +0.2 639,858 + BBR_RS12875 0.79 -0.4 639,882 + BBR_RS12875 0.81 +0.3 639,890 - BBR_RS12875 0.81 +1.8 639,892 + BBR_RS12875 0.81 +0.7 639,892 + BBR_RS12875 0.81 +0.1 639,894 + BBR_RS12875 0.82 -0.7 639,900 - BBR_RS12875 0.82 -2.3 639,943 + BBR_RS12875 0.86 -1.7 639,956 - BBR_RS12875 0.87 -0.6 639,975 + BBR_RS12875 0.89 -0.6 640,029 - -1.2 640,065 - -0.6 640,065 - -1.7 640,071 + +0.8 640,079 - -2.2 640,079 - +0.6 640,079 - +1.9 640,079 - +1.6 640,079 - -0.1 640,125 - -0.0 640,204 + +0.2 640,204 + -0.4 640,204 + +0.3 640,204 + +0.0 640,209 + -0.2 640,212 - -0.6 640,212 - -0.8 640,212 - -2.0 640,224 - +1.2 640,269 + +1.6 640,271 + +0.9 640,281 + +1.0 640,281 + +1.2 640,289 - -1.3 640,327 - BBR_RS12880 0.15 +1.1 640,379 - BBR_RS12880 0.22 -0.4 640,394 + BBR_RS12880 0.24 +0.6 640,398 - BBR_RS12880 0.25 +0.4 640,413 + BBR_RS12880 0.27 +0.4 640,421 - BBR_RS12880 0.28 -3.2 640,463 + BBR_RS12880 0.34 +1.2 640,483 - BBR_RS12880 0.37 -0.8 640,527 + BBR_RS12880 0.43 -0.4 640,563 + BBR_RS12880 0.48 +1.2 640,585 + BBR_RS12880 0.51 +1.1 640,622 + BBR_RS12880 0.56 +1.0 640,622 + BBR_RS12880 0.56 +0.5 640,635 + BBR_RS12880 0.58 +1.0 640,643 - BBR_RS12880 0.59 +0.5 640,673 + BBR_RS12880 0.63 +1.7 640,678 + BBR_RS12880 0.64 +1.0 640,686 + BBR_RS12880 0.65 +0.5 640,696 - BBR_RS12880 0.66 -1.7 640,710 + BBR_RS12880 0.68 +1.6 640,717 + BBR_RS12880 0.69 +0.6 640,718 - BBR_RS12880 0.69 -0.1 640,722 + BBR_RS12880 0.70 +0.4 640,747 - BBR_RS12880 0.73 +0.8 640,761 - BBR_RS12880 0.75 +0.9 640,787 + BBR_RS12880 0.79 +1.6 640,787 + BBR_RS12880 0.79 +0.8 640,808 - BBR_RS12880 0.82 +2.0 640,809 + BBR_RS12880 0.82 +1.3 640,828 + BBR_RS12880 0.85 +0.4 640,882 - -0.2 640,940 - -1.3 640,988 + -0.0 640,996 - -1.1 641,038 - -0.1 641,050 - -0.4
Or see this region's nucleotide sequence