Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_3766 and Pf1N1B4_3767 are separated by 459 nucleotides Pf1N1B4_3767 and Pf1N1B4_3768 are separated by 221 nucleotides Pf1N1B4_3768 and Pf1N1B4_3769 are separated by 79 nucleotides
Pf1N1B4_3766 - Uricase (urate oxidase) (EC 1.7.3.3), at 4,176,848 to 4,177,774
_3766
Pf1N1B4_3767 - 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17), at 4,178,234 to 4,178,563
_3767
Pf1N1B4_3768 - Homoserine/homoserine lactone efflux protein, at 4,178,785 to 4,179,411
_3768
Pf1N1B4_3769 - Xanthine/uracil/thiamine/ascorbate permease family protein, at 4,179,491 to 4,180,840
_3769
Position (kb)
4178
4179 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 4177.284 kb on + strand, within Pf1N1B4_3766 at 4177.285 kb on - strand, within Pf1N1B4_3766 at 4177.371 kb on + strand, within Pf1N1B4_3766 at 4177.371 kb on + strand, within Pf1N1B4_3766 at 4177.371 kb on + strand, within Pf1N1B4_3766 at 4177.371 kb on + strand, within Pf1N1B4_3766 at 4177.372 kb on - strand, within Pf1N1B4_3766 at 4177.372 kb on - strand, within Pf1N1B4_3766 at 4177.377 kb on + strand, within Pf1N1B4_3766 at 4177.545 kb on + strand, within Pf1N1B4_3766 at 4177.545 kb on + strand, within Pf1N1B4_3766 at 4177.671 kb on + strand, within Pf1N1B4_3766 at 4177.671 kb on + strand, within Pf1N1B4_3766 at 4177.672 kb on - strand, within Pf1N1B4_3766 at 4177.672 kb on - strand, within Pf1N1B4_3766 at 4177.672 kb on - strand, within Pf1N1B4_3766 at 4177.887 kb on + strand at 4177.889 kb on + strand at 4177.890 kb on - strand at 4177.900 kb on + strand at 4177.983 kb on + strand at 4177.983 kb on + strand at 4177.983 kb on + strand at 4177.983 kb on + strand at 4177.983 kb on + strand at 4177.984 kb on - strand at 4178.001 kb on + strand at 4178.001 kb on + strand at 4178.001 kb on + strand at 4178.001 kb on + strand at 4178.002 kb on - strand at 4178.002 kb on - strand at 4178.002 kb on - strand at 4178.068 kb on - strand at 4178.225 kb on - strand at 4178.282 kb on + strand, within Pf1N1B4_3767 at 4178.282 kb on + strand, within Pf1N1B4_3767 at 4178.390 kb on + strand, within Pf1N1B4_3767 at 4178.390 kb on + strand, within Pf1N1B4_3767 at 4178.390 kb on + strand, within Pf1N1B4_3767 at 4178.417 kb on + strand, within Pf1N1B4_3767 at 4178.417 kb on + strand, within Pf1N1B4_3767 at 4178.417 kb on + strand, within Pf1N1B4_3767 at 4178.417 kb on + strand, within Pf1N1B4_3767 at 4178.418 kb on - strand, within Pf1N1B4_3767 at 4178.507 kb on + strand, within Pf1N1B4_3767 at 4178.534 kb on + strand at 4178.534 kb on + strand at 4178.535 kb on - strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.540 kb on + strand at 4178.541 kb on - strand at 4178.541 kb on - strand at 4178.549 kb on + strand at 4178.603 kb on + strand at 4178.603 kb on + strand at 4178.603 kb on + strand at 4178.603 kb on + strand at 4178.603 kb on + strand at 4178.603 kb on + strand at 4178.603 kb on + strand at 4178.604 kb on - strand at 4178.604 kb on - strand at 4178.604 kb on - strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.605 kb on + strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.606 kb on - strand at 4178.725 kb on - strand at 4178.725 kb on - strand at 4178.725 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.729 kb on - strand at 4178.734 kb on - strand at 4178.734 kb on - strand at 4179.158 kb on + strand, within Pf1N1B4_3768 at 4179.159 kb on - strand, within Pf1N1B4_3768 at 4179.159 kb on - strand, within Pf1N1B4_3768 at 4179.167 kb on + strand, within Pf1N1B4_3768 at 4179.167 kb on + strand, within Pf1N1B4_3768 at 4179.168 kb on - strand, within Pf1N1B4_3768 at 4179.312 kb on - strand, within Pf1N1B4_3768 at 4179.424 kb on + strand at 4179.424 kb on + strand at 4179.424 kb on + strand at 4179.424 kb on + strand at 4179.424 kb on + strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.425 kb on - strand at 4179.427 kb on - strand at 4179.483 kb on + strand at 4179.483 kb on + strand at 4179.493 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 4,177,284 + Pf1N1B4_3766 0.47 -1.4 4,177,285 - Pf1N1B4_3766 0.47 +0.6 4,177,371 + Pf1N1B4_3766 0.56 +1.0 4,177,371 + Pf1N1B4_3766 0.56 +0.8 4,177,371 + Pf1N1B4_3766 0.56 -0.1 4,177,371 + Pf1N1B4_3766 0.56 +0.3 4,177,372 - Pf1N1B4_3766 0.57 +1.4 4,177,372 - Pf1N1B4_3766 0.57 -0.9 4,177,377 + Pf1N1B4_3766 0.57 -0.2 4,177,545 + Pf1N1B4_3766 0.75 +1.1 4,177,545 + Pf1N1B4_3766 0.75 -1.2 4,177,671 + Pf1N1B4_3766 0.89 +0.7 4,177,671 + Pf1N1B4_3766 0.89 +1.6 4,177,672 - Pf1N1B4_3766 0.89 -0.2 4,177,672 - Pf1N1B4_3766 0.89 -0.2 4,177,672 - Pf1N1B4_3766 0.89 +2.1 4,177,887 + -0.2 4,177,889 + -1.2 4,177,890 - +2.3 4,177,900 + -0.2 4,177,983 + +0.8 4,177,983 + -1.2 4,177,983 + +0.6 4,177,983 + -0.2 4,177,983 + -0.4 4,177,984 - -0.2 4,178,001 + -0.7 4,178,001 + -0.9 4,178,001 + -0.2 4,178,001 + -1.8 4,178,002 - +1.0 4,178,002 - -0.2 4,178,002 - +2.1 4,178,068 - -1.8 4,178,225 - +0.8 4,178,282 + Pf1N1B4_3767 0.15 -1.8 4,178,282 + Pf1N1B4_3767 0.15 -1.0 4,178,390 + Pf1N1B4_3767 0.47 +0.0 4,178,390 + Pf1N1B4_3767 0.47 -0.4 4,178,390 + Pf1N1B4_3767 0.47 -0.2 4,178,417 + Pf1N1B4_3767 0.55 -0.8 4,178,417 + Pf1N1B4_3767 0.55 -3.0 4,178,417 + Pf1N1B4_3767 0.55 +0.7 4,178,417 + Pf1N1B4_3767 0.55 -0.8 4,178,418 - Pf1N1B4_3767 0.56 -1.2 4,178,507 + Pf1N1B4_3767 0.83 -0.9 4,178,534 + -0.9 4,178,534 + -0.5 4,178,535 - -0.2 4,178,540 + -0.2 4,178,540 + -0.6 4,178,540 + -0.6 4,178,540 + +0.6 4,178,540 + +0.5 4,178,540 + +1.0 4,178,540 + +0.4 4,178,540 + -0.2 4,178,541 - +1.1 4,178,541 - -1.2 4,178,549 + -0.5 4,178,603 + -0.2 4,178,603 + -0.5 4,178,603 + +0.4 4,178,603 + -0.2 4,178,603 + -2.3 4,178,603 + -0.2 4,178,603 + -0.8 4,178,604 - -0.4 4,178,604 - +2.4 4,178,604 - +1.8 4,178,605 + +0.2 4,178,605 + +0.9 4,178,605 + -0.2 4,178,605 + -1.2 4,178,605 + +0.2 4,178,605 + -0.2 4,178,605 + -3.0 4,178,605 + -0.7 4,178,605 + +2.4 4,178,605 + -0.2 4,178,605 + +0.4 4,178,605 + -1.4 4,178,605 + -2.2 4,178,605 + -3.2 4,178,606 - -1.2 4,178,606 - -0.2 4,178,606 - +0.1 4,178,606 - -1.5 4,178,606 - -0.5 4,178,606 - -1.2 4,178,606 - -0.8 4,178,606 - -0.2 4,178,606 - +0.0 4,178,606 - -0.3 4,178,606 - -1.2 4,178,725 - +3.0 4,178,725 - +0.8 4,178,725 - +0.0 4,178,729 - -0.5 4,178,729 - -0.3 4,178,729 - +1.2 4,178,729 - +1.2 4,178,729 - -1.6 4,178,729 - +2.1 4,178,729 - +1.0 4,178,729 - -0.3 4,178,729 - +0.8 4,178,729 - -1.8 4,178,734 - +1.4 4,178,734 - -0.6 4,179,158 + Pf1N1B4_3768 0.59 +0.1 4,179,159 - Pf1N1B4_3768 0.60 -0.2 4,179,159 - Pf1N1B4_3768 0.60 -1.8 4,179,167 + Pf1N1B4_3768 0.61 -0.4 4,179,167 + Pf1N1B4_3768 0.61 -0.2 4,179,168 - Pf1N1B4_3768 0.61 +0.0 4,179,312 - Pf1N1B4_3768 0.84 -0.2 4,179,424 + +0.3 4,179,424 + +0.1 4,179,424 + +0.0 4,179,424 + +1.4 4,179,424 + +0.2 4,179,425 - -0.3 4,179,425 - +0.0 4,179,425 - -0.2 4,179,425 - -2.5 4,179,425 - +2.4 4,179,425 - +1.4 4,179,425 - +0.8 4,179,425 - +1.4 4,179,425 - -1.5 4,179,427 - -0.3 4,179,483 + +0.8 4,179,483 + +1.1 4,179,493 - +0.1
Or see this region's nucleotide sequence