Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_1444 and Pf1N1B4_1445 are separated by 228 nucleotides Pf1N1B4_1445 and Pf1N1B4_1446 overlap by 32 nucleotides Pf1N1B4_1446 and Pf1N1B4_1447 are separated by 184 nucleotides
Pf1N1B4_1444 - ADP-ribose pyrophosphatase (EC 3.6.1.13), at 1,655,552 to 1,656,169
_1444
Pf1N1B4_1445 - lipoprotein, putative, at 1,656,398 to 1,657,144
_1445
Pf1N1B4_1446 - Predicted hydroxymethylpyrimidine transporter CytX, at 1,657,113 to 1,658,366
_1446
Pf1N1B4_1447 - Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17), at 1,658,551 to 1,660,440
_1447
Position (kb)
1657
1658
1659 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 1656.215 kb on - strand at 1656.313 kb on + strand at 1656.313 kb on + strand at 1656.313 kb on + strand at 1656.313 kb on + strand at 1656.313 kb on + strand at 1656.313 kb on + strand at 1656.313 kb on + strand at 1656.314 kb on - strand at 1656.314 kb on - strand at 1656.317 kb on + strand at 1656.317 kb on + strand at 1656.318 kb on - strand at 1656.318 kb on - strand at 1656.318 kb on - strand at 1656.318 kb on - strand at 1656.318 kb on - strand at 1656.322 kb on + strand at 1656.322 kb on + strand at 1656.322 kb on + strand at 1656.387 kb on - strand at 1656.477 kb on - strand, within Pf1N1B4_1445 at 1656.477 kb on - strand, within Pf1N1B4_1445 at 1656.496 kb on + strand, within Pf1N1B4_1445 at 1656.496 kb on + strand, within Pf1N1B4_1445 at 1656.654 kb on + strand, within Pf1N1B4_1445 at 1656.654 kb on + strand, within Pf1N1B4_1445 at 1656.655 kb on - strand, within Pf1N1B4_1445 at 1656.655 kb on - strand, within Pf1N1B4_1445 at 1656.655 kb on - strand, within Pf1N1B4_1445 at 1656.655 kb on - strand at 1656.719 kb on + strand, within Pf1N1B4_1445 at 1656.719 kb on + strand, within Pf1N1B4_1445 at 1656.719 kb on + strand, within Pf1N1B4_1445 at 1656.719 kb on + strand, within Pf1N1B4_1445 at 1656.720 kb on - strand, within Pf1N1B4_1445 at 1656.720 kb on - strand, within Pf1N1B4_1445 at 1656.720 kb on - strand, within Pf1N1B4_1445 at 1656.720 kb on - strand, within Pf1N1B4_1445 at 1656.735 kb on + strand, within Pf1N1B4_1445 at 1656.735 kb on + strand, within Pf1N1B4_1445 at 1656.735 kb on + strand, within Pf1N1B4_1445 at 1656.736 kb on - strand, within Pf1N1B4_1445 at 1656.736 kb on - strand, within Pf1N1B4_1445 at 1656.736 kb on - strand, within Pf1N1B4_1445 at 1656.736 kb on - strand, within Pf1N1B4_1445 at 1656.736 kb on - strand, within Pf1N1B4_1445 at 1656.779 kb on + strand, within Pf1N1B4_1445 at 1656.780 kb on - strand, within Pf1N1B4_1445 at 1656.780 kb on - strand, within Pf1N1B4_1445 at 1656.780 kb on - strand, within Pf1N1B4_1445 at 1656.780 kb on - strand, within Pf1N1B4_1445 at 1656.830 kb on + strand at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.830 kb on + strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.831 kb on - strand, within Pf1N1B4_1445 at 1656.847 kb on + strand at 1656.847 kb on + strand, within Pf1N1B4_1445 at 1656.847 kb on + strand, within Pf1N1B4_1445 at 1656.848 kb on - strand, within Pf1N1B4_1445 at 1656.848 kb on - strand, within Pf1N1B4_1445 at 1656.848 kb on - strand, within Pf1N1B4_1445 at 1656.848 kb on - strand, within Pf1N1B4_1445 at 1656.848 kb on - strand at 1656.848 kb on - strand, within Pf1N1B4_1445 at 1657.014 kb on - strand, within Pf1N1B4_1445 at 1657.034 kb on + strand, within Pf1N1B4_1445 at 1657.034 kb on + strand, within Pf1N1B4_1445 at 1657.035 kb on - strand, within Pf1N1B4_1445 at 1657.035 kb on - strand, within Pf1N1B4_1445 at 1657.035 kb on - strand at 1657.139 kb on - strand at 1657.237 kb on + strand at 1657.238 kb on - strand at 1657.238 kb on - strand at 1657.238 kb on - strand at 1657.238 kb on - strand at 1657.238 kb on - strand at 1657.296 kb on + strand, within Pf1N1B4_1446 at 1657.378 kb on - strand, within Pf1N1B4_1446 at 1657.630 kb on + strand at 1657.630 kb on + strand, within Pf1N1B4_1446 at 1657.868 kb on + strand, within Pf1N1B4_1446 at 1657.869 kb on - strand, within Pf1N1B4_1446 at 1657.869 kb on - strand, within Pf1N1B4_1446 at 1657.869 kb on - strand, within Pf1N1B4_1446 at 1657.869 kb on - strand, within Pf1N1B4_1446 at 1657.869 kb on - strand, within Pf1N1B4_1446 at 1657.893 kb on - strand, within Pf1N1B4_1446 at 1658.383 kb on + strand at 1658.383 kb on + strand at 1658.383 kb on + strand at 1658.384 kb on - strand at 1658.384 kb on - strand at 1658.384 kb on - strand at 1658.384 kb on - strand at 1658.384 kb on - strand at 1658.412 kb on + strand at 1658.412 kb on + strand at 1658.413 kb on - strand at 1658.413 kb on - strand at 1658.413 kb on - strand at 1658.413 kb on - strand at 1658.413 kb on - strand at 1658.565 kb on - strand at 1658.565 kb on - strand at 1658.765 kb on + strand, within Pf1N1B4_1447 at 1658.766 kb on - strand, within Pf1N1B4_1447 at 1658.766 kb on - strand, within Pf1N1B4_1447 at 1658.909 kb on + strand, within Pf1N1B4_1447 at 1658.909 kb on + strand, within Pf1N1B4_1447 at 1658.910 kb on - strand, within Pf1N1B4_1447 at 1658.910 kb on - strand, within Pf1N1B4_1447 at 1658.910 kb on - strand, within Pf1N1B4_1447 at 1658.910 kb on - strand, within Pf1N1B4_1447 at 1658.910 kb on - strand at 1658.910 kb on - strand, within Pf1N1B4_1447 at 1658.910 kb on - strand, within Pf1N1B4_1447 at 1658.975 kb on + strand, within Pf1N1B4_1447 at 1658.975 kb on + strand, within Pf1N1B4_1447 at 1658.976 kb on - strand, within Pf1N1B4_1447 at 1659.080 kb on + strand, within Pf1N1B4_1447 at 1659.081 kb on - strand, within Pf1N1B4_1447 at 1659.081 kb on - strand, within Pf1N1B4_1447 at 1659.175 kb on + strand, within Pf1N1B4_1447 at 1659.175 kb on + strand, within Pf1N1B4_1447 at 1659.175 kb on + strand, within Pf1N1B4_1447 at 1659.175 kb on + strand, within Pf1N1B4_1447 at 1659.175 kb on + strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.176 kb on - strand, within Pf1N1B4_1447 at 1659.302 kb on + strand, within Pf1N1B4_1447 at 1659.302 kb on + strand, within Pf1N1B4_1447 at 1659.342 kb on - strand, within Pf1N1B4_1447 at 1659.357 kb on + strand, within Pf1N1B4_1447 at 1659.357 kb on + strand, within Pf1N1B4_1447 at 1659.358 kb on - strand, within Pf1N1B4_1447
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 1,656,215 - +1.5 1,656,313 + +1.0 1,656,313 + +0.2 1,656,313 + +0.7 1,656,313 + +0.5 1,656,313 + +1.2 1,656,313 + -1.8 1,656,313 + -0.4 1,656,314 - +3.0 1,656,314 - -1.4 1,656,317 + +1.2 1,656,317 + +1.8 1,656,318 - +0.0 1,656,318 - -0.8 1,656,318 - +0.8 1,656,318 - -0.0 1,656,318 - +1.2 1,656,322 + +0.2 1,656,322 + +0.6 1,656,322 + -1.6 1,656,387 - +1.6 1,656,477 - Pf1N1B4_1445 0.11 +0.4 1,656,477 - Pf1N1B4_1445 0.11 +0.4 1,656,496 + Pf1N1B4_1445 0.13 +0.8 1,656,496 + Pf1N1B4_1445 0.13 +0.4 1,656,654 + Pf1N1B4_1445 0.34 +1.2 1,656,654 + Pf1N1B4_1445 0.34 +0.3 1,656,655 - Pf1N1B4_1445 0.34 +1.5 1,656,655 - Pf1N1B4_1445 0.34 -0.5 1,656,655 - Pf1N1B4_1445 0.34 +1.0 1,656,655 - +0.2 1,656,719 + Pf1N1B4_1445 0.43 +0.4 1,656,719 + Pf1N1B4_1445 0.43 +0.2 1,656,719 + Pf1N1B4_1445 0.43 +0.2 1,656,719 + Pf1N1B4_1445 0.43 +0.2 1,656,720 - Pf1N1B4_1445 0.43 -0.7 1,656,720 - Pf1N1B4_1445 0.43 -0.0 1,656,720 - Pf1N1B4_1445 0.43 -1.2 1,656,720 - Pf1N1B4_1445 0.43 +0.1 1,656,735 + Pf1N1B4_1445 0.45 +0.2 1,656,735 + Pf1N1B4_1445 0.45 +1.0 1,656,735 + Pf1N1B4_1445 0.45 -1.0 1,656,736 - Pf1N1B4_1445 0.45 -0.2 1,656,736 - Pf1N1B4_1445 0.45 +2.5 1,656,736 - Pf1N1B4_1445 0.45 -1.4 1,656,736 - Pf1N1B4_1445 0.45 +0.4 1,656,736 - Pf1N1B4_1445 0.45 +1.8 1,656,779 + Pf1N1B4_1445 0.51 -0.5 1,656,780 - Pf1N1B4_1445 0.51 +0.8 1,656,780 - Pf1N1B4_1445 0.51 +1.8 1,656,780 - Pf1N1B4_1445 0.51 +0.2 1,656,780 - Pf1N1B4_1445 0.51 -0.9 1,656,830 + +1.2 1,656,830 + Pf1N1B4_1445 0.58 -1.7 1,656,830 + Pf1N1B4_1445 0.58 -1.2 1,656,830 + Pf1N1B4_1445 0.58 +0.8 1,656,830 + Pf1N1B4_1445 0.58 +0.6 1,656,830 + Pf1N1B4_1445 0.58 +0.6 1,656,830 + Pf1N1B4_1445 0.58 -0.8 1,656,830 + Pf1N1B4_1445 0.58 -1.4 1,656,831 - Pf1N1B4_1445 0.58 -0.8 1,656,831 - Pf1N1B4_1445 0.58 -0.1 1,656,831 - Pf1N1B4_1445 0.58 -1.5 1,656,831 - Pf1N1B4_1445 0.58 -0.0 1,656,831 - Pf1N1B4_1445 0.58 +1.0 1,656,831 - Pf1N1B4_1445 0.58 -0.5 1,656,831 - Pf1N1B4_1445 0.58 +1.2 1,656,847 + +0.2 1,656,847 + Pf1N1B4_1445 0.60 -1.5 1,656,847 + Pf1N1B4_1445 0.60 -0.8 1,656,848 - Pf1N1B4_1445 0.60 -0.3 1,656,848 - Pf1N1B4_1445 0.60 +1.6 1,656,848 - Pf1N1B4_1445 0.60 +0.9 1,656,848 - Pf1N1B4_1445 0.60 +2.0 1,656,848 - -1.4 1,656,848 - Pf1N1B4_1445 0.60 +1.2 1,657,014 - Pf1N1B4_1445 0.82 -0.2 1,657,034 + Pf1N1B4_1445 0.85 -1.0 1,657,034 + Pf1N1B4_1445 0.85 +2.2 1,657,035 - Pf1N1B4_1445 0.85 +0.8 1,657,035 - Pf1N1B4_1445 0.85 +0.2 1,657,035 - -0.8 1,657,139 - -0.2 1,657,237 + -0.5 1,657,238 - -0.8 1,657,238 - +0.8 1,657,238 - -0.1 1,657,238 - +0.5 1,657,238 - -0.3 1,657,296 + Pf1N1B4_1446 0.15 -0.8 1,657,378 - Pf1N1B4_1446 0.21 -0.0 1,657,630 + +0.2 1,657,630 + Pf1N1B4_1446 0.41 -2.4 1,657,868 + Pf1N1B4_1446 0.60 +0.2 1,657,869 - Pf1N1B4_1446 0.60 -2.1 1,657,869 - Pf1N1B4_1446 0.60 +1.0 1,657,869 - Pf1N1B4_1446 0.60 -0.8 1,657,869 - Pf1N1B4_1446 0.60 -2.4 1,657,869 - Pf1N1B4_1446 0.60 -0.5 1,657,893 - Pf1N1B4_1446 0.62 +0.2 1,658,383 + -0.4 1,658,383 + -0.8 1,658,383 + +0.4 1,658,384 - -0.5 1,658,384 - +0.2 1,658,384 - -1.8 1,658,384 - +0.6 1,658,384 - -0.8 1,658,412 + -0.6 1,658,412 + -1.2 1,658,413 - +1.8 1,658,413 - +2.0 1,658,413 - -1.8 1,658,413 - +2.3 1,658,413 - +1.1 1,658,565 - -1.0 1,658,565 - +1.7 1,658,765 + Pf1N1B4_1447 0.11 -0.2 1,658,766 - Pf1N1B4_1447 0.11 -1.5 1,658,766 - Pf1N1B4_1447 0.11 +1.2 1,658,909 + Pf1N1B4_1447 0.19 +1.8 1,658,909 + Pf1N1B4_1447 0.19 -2.4 1,658,910 - Pf1N1B4_1447 0.19 +0.1 1,658,910 - Pf1N1B4_1447 0.19 +0.2 1,658,910 - Pf1N1B4_1447 0.19 -0.3 1,658,910 - Pf1N1B4_1447 0.19 -0.6 1,658,910 - -0.4 1,658,910 - Pf1N1B4_1447 0.19 +1.2 1,658,910 - Pf1N1B4_1447 0.19 +1.4 1,658,975 + Pf1N1B4_1447 0.22 +0.4 1,658,975 + Pf1N1B4_1447 0.22 +0.5 1,658,976 - Pf1N1B4_1447 0.22 +0.1 1,659,080 + Pf1N1B4_1447 0.28 +0.6 1,659,081 - Pf1N1B4_1447 0.28 +2.2 1,659,081 - Pf1N1B4_1447 0.28 -0.8 1,659,175 + Pf1N1B4_1447 0.33 -1.1 1,659,175 + Pf1N1B4_1447 0.33 -0.5 1,659,175 + Pf1N1B4_1447 0.33 -0.8 1,659,175 + Pf1N1B4_1447 0.33 -0.5 1,659,175 + Pf1N1B4_1447 0.33 +0.5 1,659,176 - Pf1N1B4_1447 0.33 -2.1 1,659,176 - Pf1N1B4_1447 0.33 +0.8 1,659,176 - Pf1N1B4_1447 0.33 +0.2 1,659,176 - Pf1N1B4_1447 0.33 +0.2 1,659,176 - Pf1N1B4_1447 0.33 -1.8 1,659,176 - Pf1N1B4_1447 0.33 +0.2 1,659,176 - Pf1N1B4_1447 0.33 +1.4 1,659,302 + Pf1N1B4_1447 0.40 -1.0 1,659,302 + Pf1N1B4_1447 0.40 +0.2 1,659,342 - Pf1N1B4_1447 0.42 -0.3 1,659,357 + Pf1N1B4_1447 0.43 +1.2 1,659,357 + Pf1N1B4_1447 0.43 -1.4 1,659,358 - Pf1N1B4_1447 0.43 +1.1
Or see this region's nucleotide sequence