Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_1114 and Pf1N1B4_1115 are separated by 96 nucleotides Pf1N1B4_1115 and Pf1N1B4_1116 overlap by 8 nucleotides
Pf1N1B4_1114 - ABC transporter, ATP-binding protein, at 1,248,248 to 1,249,975
_1114
Pf1N1B4_1115 - Dna binding response regulator PrrA (RegA), at 1,250,072 to 1,250,632
_1115
Pf1N1B4_1116 - Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-), at 1,250,625 to 1,251,887
_1116
Position (kb)
1250
1251 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 1249.236 kb on + strand, within Pf1N1B4_1114 at 1249.272 kb on - strand, within Pf1N1B4_1114 at 1249.398 kb on + strand, within Pf1N1B4_1114 at 1249.570 kb on - strand, within Pf1N1B4_1114 at 1249.594 kb on - strand, within Pf1N1B4_1114 at 1249.594 kb on - strand, within Pf1N1B4_1114 at 1249.725 kb on + strand, within Pf1N1B4_1114 at 1249.777 kb on - strand, within Pf1N1B4_1114 at 1249.777 kb on - strand, within Pf1N1B4_1114 at 1249.957 kb on - strand at 1249.989 kb on + strand at 1249.990 kb on - strand at 1250.018 kb on + strand at 1250.019 kb on - strand at 1250.019 kb on - strand at 1250.174 kb on + strand, within Pf1N1B4_1115 at 1250.175 kb on - strand, within Pf1N1B4_1115 at 1250.175 kb on - strand, within Pf1N1B4_1115 at 1250.175 kb on - strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.304 kb on + strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.305 kb on - strand, within Pf1N1B4_1115 at 1250.457 kb on + strand, within Pf1N1B4_1115 at 1250.457 kb on + strand, within Pf1N1B4_1115 at 1250.458 kb on - strand, within Pf1N1B4_1115 at 1250.458 kb on - strand, within Pf1N1B4_1115 at 1250.465 kb on + strand, within Pf1N1B4_1115 at 1250.465 kb on + strand, within Pf1N1B4_1115 at 1250.465 kb on + strand, within Pf1N1B4_1115 at 1250.465 kb on + strand, within Pf1N1B4_1115 at 1250.465 kb on + strand, within Pf1N1B4_1115 at 1250.466 kb on - strand, within Pf1N1B4_1115 at 1250.466 kb on - strand at 1250.466 kb on - strand, within Pf1N1B4_1115 at 1250.468 kb on - strand, within Pf1N1B4_1115 at 1250.512 kb on + strand, within Pf1N1B4_1115 at 1250.513 kb on - strand, within Pf1N1B4_1115 at 1250.579 kb on + strand at 1250.579 kb on + strand at 1250.580 kb on - strand at 1250.580 kb on - strand at 1250.580 kb on - strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.698 kb on + strand at 1250.699 kb on - strand at 1250.699 kb on - strand at 1250.699 kb on - strand at 1250.699 kb on - strand at 1250.699 kb on - strand at 1250.780 kb on + strand, within Pf1N1B4_1116 at 1250.780 kb on + strand, within Pf1N1B4_1116 at 1250.781 kb on - strand, within Pf1N1B4_1116 at 1250.781 kb on - strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.285 kb on + strand, within Pf1N1B4_1116 at 1251.286 kb on - strand, within Pf1N1B4_1116 at 1251.286 kb on - strand, within Pf1N1B4_1116 at 1251.286 kb on - strand at 1251.418 kb on + strand, within Pf1N1B4_1116 at 1251.418 kb on + strand, within Pf1N1B4_1116 at 1251.418 kb on + strand, within Pf1N1B4_1116 at 1251.419 kb on - strand, within Pf1N1B4_1116 at 1251.463 kb on + strand, within Pf1N1B4_1116 at 1251.487 kb on + strand, within Pf1N1B4_1116 at 1251.487 kb on + strand, within Pf1N1B4_1116 at 1251.487 kb on + strand, within Pf1N1B4_1116 at 1251.487 kb on + strand, within Pf1N1B4_1116 at 1251.488 kb on - strand, within Pf1N1B4_1116 at 1251.568 kb on + strand, within Pf1N1B4_1116 at 1251.568 kb on + strand, within Pf1N1B4_1116 at 1251.568 kb on + strand, within Pf1N1B4_1116 at 1251.568 kb on + strand, within Pf1N1B4_1116 at 1251.568 kb on + strand, within Pf1N1B4_1116 at 1251.569 kb on - strand, within Pf1N1B4_1116 at 1251.569 kb on - strand, within Pf1N1B4_1116 at 1251.569 kb on - strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.571 kb on + strand, within Pf1N1B4_1116 at 1251.572 kb on - strand, within Pf1N1B4_1116 at 1251.572 kb on - strand, within Pf1N1B4_1116 at 1251.572 kb on - strand at 1251.572 kb on - strand, within Pf1N1B4_1116 at 1251.572 kb on - strand, within Pf1N1B4_1116 at 1251.572 kb on - strand, within Pf1N1B4_1116 at 1251.572 kb on - strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.607 kb on + strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.608 kb on - strand, within Pf1N1B4_1116 at 1251.626 kb on + strand, within Pf1N1B4_1116 at 1251.627 kb on - strand, within Pf1N1B4_1116
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 1,249,236 + Pf1N1B4_1114 0.57 +0.3 1,249,272 - Pf1N1B4_1114 0.59 +1.1 1,249,398 + Pf1N1B4_1114 0.67 +0.5 1,249,570 - Pf1N1B4_1114 0.77 -2.7 1,249,594 - Pf1N1B4_1114 0.78 +1.4 1,249,594 - Pf1N1B4_1114 0.78 +1.1 1,249,725 + Pf1N1B4_1114 0.85 -0.6 1,249,777 - Pf1N1B4_1114 0.88 -0.9 1,249,777 - Pf1N1B4_1114 0.88 -0.9 1,249,957 - +1.9 1,249,989 + +0.3 1,249,990 - +0.1 1,250,018 + +0.4 1,250,019 - +0.1 1,250,019 - +0.6 1,250,174 + Pf1N1B4_1115 0.18 +0.3 1,250,175 - Pf1N1B4_1115 0.18 -1.9 1,250,175 - Pf1N1B4_1115 0.18 -0.3 1,250,175 - Pf1N1B4_1115 0.18 -1.9 1,250,304 + Pf1N1B4_1115 0.41 +2.1 1,250,304 + Pf1N1B4_1115 0.41 -1.0 1,250,304 + Pf1N1B4_1115 0.41 -2.9 1,250,304 + Pf1N1B4_1115 0.41 -0.9 1,250,304 + Pf1N1B4_1115 0.41 -1.9 1,250,304 + Pf1N1B4_1115 0.41 -0.6 1,250,304 + Pf1N1B4_1115 0.41 -0.6 1,250,304 + Pf1N1B4_1115 0.41 +1.1 1,250,304 + Pf1N1B4_1115 0.41 -1.7 1,250,304 + Pf1N1B4_1115 0.41 -0.5 1,250,304 + Pf1N1B4_1115 0.41 -0.6 1,250,304 + Pf1N1B4_1115 0.41 -0.6 1,250,304 + Pf1N1B4_1115 0.41 +0.5 1,250,304 + Pf1N1B4_1115 0.41 -1.2 1,250,304 + Pf1N1B4_1115 0.41 -2.2 1,250,304 + Pf1N1B4_1115 0.41 -1.5 1,250,304 + Pf1N1B4_1115 0.41 -0.6 1,250,304 + Pf1N1B4_1115 0.41 -0.9 1,250,304 + Pf1N1B4_1115 0.41 +0.5 1,250,304 + Pf1N1B4_1115 0.41 -0.8 1,250,304 + Pf1N1B4_1115 0.41 -0.4 1,250,304 + Pf1N1B4_1115 0.41 +0.3 1,250,305 - Pf1N1B4_1115 0.42 -0.9 1,250,305 - Pf1N1B4_1115 0.42 -0.9 1,250,305 - Pf1N1B4_1115 0.42 +0.1 1,250,305 - Pf1N1B4_1115 0.42 -1.1 1,250,305 - Pf1N1B4_1115 0.42 +1.7 1,250,305 - Pf1N1B4_1115 0.42 -1.0 1,250,305 - +0.7 1,250,305 - Pf1N1B4_1115 0.42 +1.0 1,250,305 - Pf1N1B4_1115 0.42 -2.3 1,250,305 - Pf1N1B4_1115 0.42 -1.2 1,250,305 - Pf1N1B4_1115 0.42 -1.5 1,250,305 - Pf1N1B4_1115 0.42 -0.5 1,250,305 - Pf1N1B4_1115 0.42 -1.1 1,250,305 - Pf1N1B4_1115 0.42 -1.9 1,250,305 - Pf1N1B4_1115 0.42 -1.9 1,250,305 - Pf1N1B4_1115 0.42 +0.8 1,250,305 - Pf1N1B4_1115 0.42 -2.1 1,250,305 - Pf1N1B4_1115 0.42 -1.0 1,250,305 - Pf1N1B4_1115 0.42 +1.4 1,250,305 - Pf1N1B4_1115 0.42 +0.1 1,250,457 + Pf1N1B4_1115 0.69 -0.1 1,250,457 + Pf1N1B4_1115 0.69 -1.2 1,250,458 - Pf1N1B4_1115 0.69 -0.2 1,250,458 - Pf1N1B4_1115 0.69 -1.0 1,250,465 + Pf1N1B4_1115 0.70 -0.2 1,250,465 + Pf1N1B4_1115 0.70 -0.9 1,250,465 + Pf1N1B4_1115 0.70 -1.6 1,250,465 + Pf1N1B4_1115 0.70 -0.4 1,250,465 + Pf1N1B4_1115 0.70 -0.3 1,250,466 - Pf1N1B4_1115 0.70 -0.7 1,250,466 - +0.1 1,250,466 - Pf1N1B4_1115 0.70 +0.1 1,250,468 - Pf1N1B4_1115 0.71 -0.5 1,250,512 + Pf1N1B4_1115 0.78 -0.6 1,250,513 - Pf1N1B4_1115 0.79 -1.2 1,250,579 + -1.5 1,250,579 + -1.9 1,250,580 - -0.9 1,250,580 - -0.5 1,250,580 - -1.1 1,250,698 + +0.9 1,250,698 + +1.7 1,250,698 + -0.9 1,250,698 + -2.6 1,250,698 + -0.5 1,250,698 + +0.7 1,250,698 + -0.5 1,250,698 + -1.0 1,250,699 - -2.7 1,250,699 - +0.1 1,250,699 - -0.6 1,250,699 - -1.2 1,250,699 - +1.0 1,250,780 + Pf1N1B4_1116 0.12 -1.0 1,250,780 + Pf1N1B4_1116 0.12 +0.1 1,250,781 - Pf1N1B4_1116 0.12 -1.5 1,250,781 - Pf1N1B4_1116 0.12 +0.5 1,251,285 + Pf1N1B4_1116 0.52 +0.4 1,251,285 + Pf1N1B4_1116 0.52 -1.5 1,251,285 + Pf1N1B4_1116 0.52 -0.7 1,251,285 + Pf1N1B4_1116 0.52 -2.5 1,251,285 + Pf1N1B4_1116 0.52 -0.5 1,251,285 + Pf1N1B4_1116 0.52 -1.1 1,251,285 + Pf1N1B4_1116 0.52 -0.6 1,251,285 + Pf1N1B4_1116 0.52 -2.5 1,251,285 + Pf1N1B4_1116 0.52 -1.5 1,251,285 + Pf1N1B4_1116 0.52 -0.9 1,251,285 + Pf1N1B4_1116 0.52 -1.0 1,251,285 + Pf1N1B4_1116 0.52 -1.5 1,251,286 - Pf1N1B4_1116 0.52 +1.3 1,251,286 - Pf1N1B4_1116 0.52 -1.5 1,251,286 - +1.1 1,251,418 + Pf1N1B4_1116 0.63 -0.3 1,251,418 + Pf1N1B4_1116 0.63 -2.9 1,251,418 + Pf1N1B4_1116 0.63 +0.6 1,251,419 - Pf1N1B4_1116 0.63 -0.9 1,251,463 + Pf1N1B4_1116 0.66 -0.7 1,251,487 + Pf1N1B4_1116 0.68 -0.8 1,251,487 + Pf1N1B4_1116 0.68 -0.7 1,251,487 + Pf1N1B4_1116 0.68 -0.7 1,251,487 + Pf1N1B4_1116 0.68 +0.5 1,251,488 - Pf1N1B4_1116 0.68 -0.3 1,251,568 + Pf1N1B4_1116 0.75 -1.9 1,251,568 + Pf1N1B4_1116 0.75 -2.2 1,251,568 + Pf1N1B4_1116 0.75 +0.7 1,251,568 + Pf1N1B4_1116 0.75 -3.9 1,251,568 + Pf1N1B4_1116 0.75 -2.9 1,251,569 - Pf1N1B4_1116 0.75 -1.2 1,251,569 - Pf1N1B4_1116 0.75 +0.1 1,251,569 - Pf1N1B4_1116 0.75 +0.1 1,251,571 + Pf1N1B4_1116 0.75 +0.7 1,251,571 + Pf1N1B4_1116 0.75 -0.8 1,251,571 + Pf1N1B4_1116 0.75 -0.5 1,251,571 + Pf1N1B4_1116 0.75 -1.6 1,251,571 + Pf1N1B4_1116 0.75 -2.2 1,251,571 + Pf1N1B4_1116 0.75 +0.1 1,251,571 + Pf1N1B4_1116 0.75 +0.1 1,251,571 + Pf1N1B4_1116 0.75 -0.9 1,251,571 + Pf1N1B4_1116 0.75 +1.1 1,251,571 + Pf1N1B4_1116 0.75 -1.2 1,251,571 + Pf1N1B4_1116 0.75 -2.4 1,251,571 + Pf1N1B4_1116 0.75 -1.2 1,251,571 + Pf1N1B4_1116 0.75 +0.5 1,251,571 + Pf1N1B4_1116 0.75 -1.3 1,251,571 + Pf1N1B4_1116 0.75 -0.1 1,251,571 + Pf1N1B4_1116 0.75 -1.9 1,251,571 + Pf1N1B4_1116 0.75 +0.1 1,251,571 + Pf1N1B4_1116 0.75 +0.1 1,251,571 + Pf1N1B4_1116 0.75 -2.5 1,251,571 + Pf1N1B4_1116 0.75 -2.2 1,251,572 - Pf1N1B4_1116 0.75 -1.2 1,251,572 - Pf1N1B4_1116 0.75 -1.2 1,251,572 - -0.9 1,251,572 - Pf1N1B4_1116 0.75 -0.8 1,251,572 - Pf1N1B4_1116 0.75 -0.6 1,251,572 - Pf1N1B4_1116 0.75 +1.1 1,251,572 - Pf1N1B4_1116 0.75 -1.7 1,251,607 + Pf1N1B4_1116 0.78 -2.2 1,251,607 + Pf1N1B4_1116 0.78 -0.9 1,251,607 + Pf1N1B4_1116 0.78 +0.9 1,251,607 + Pf1N1B4_1116 0.78 -3.1 1,251,607 + Pf1N1B4_1116 0.78 -1.9 1,251,607 + Pf1N1B4_1116 0.78 -0.2 1,251,607 + Pf1N1B4_1116 0.78 -1.5 1,251,607 + Pf1N1B4_1116 0.78 -1.6 1,251,607 + Pf1N1B4_1116 0.78 -0.6 1,251,607 + Pf1N1B4_1116 0.78 -2.7 1,251,607 + Pf1N1B4_1116 0.78 +0.1 1,251,608 - Pf1N1B4_1116 0.78 -0.9 1,251,608 - Pf1N1B4_1116 0.78 -3.1 1,251,608 - Pf1N1B4_1116 0.78 -0.5 1,251,608 - Pf1N1B4_1116 0.78 -2.2 1,251,608 - Pf1N1B4_1116 0.78 +0.1 1,251,608 - Pf1N1B4_1116 0.78 +1.7 1,251,608 - +0.7 1,251,608 - Pf1N1B4_1116 0.78 +0.1 1,251,608 - Pf1N1B4_1116 0.78 -0.5 1,251,626 + Pf1N1B4_1116 0.79 +0.4 1,251,627 - Pf1N1B4_1116 0.79 -2.9
Or see this region's nucleotide sequence