Experiment: L-Histidine (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt AO353_02295 and AO353_02300 are separated by 82 nucleotides AO353_02300 and AO353_02305 are separated by 343 nucleotides AO353_02305 and AO353_02310 are separated by 65 nucleotides AO353_02310 and AO353_02315 are separated by 223 nucleotides
AO353_02295: AO353_02295 - GntR family transcriptional regulator, at 488,362 to 489,528
_02295
AO353_02300: AO353_02300 - MarR family transcriptional regulator, at 489,611 to 490,054
_02300
AO353_02305: AO353_02305 - guanine permease, at 490,398 to 491,747
_02305
AO353_02310: AO353_02310 - lysine transporter LysE, at 491,813 to 492,439
_02310
AO353_02315: AO353_02315 - 5-hydroxyisourate hydrolase, at 492,663 to 493,016
_02315
Position (kb) 490
491
492 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3
4 at 489.499 kb on - strand at 489.499 kb on - strand at 489.560 kb on + strand at 489.571 kb on - strand at 489.585 kb on - strand at 489.602 kb on + strand at 489.603 kb on - strand at 489.622 kb on + strand at 489.889 kb on + strand, within AO353_02300 at 489.889 kb on + strand, within AO353_02300 at 489.889 kb on + strand, within AO353_02300 at 490.000 kb on - strand, within AO353_02300 at 490.000 kb on - strand, within AO353_02300 at 490.000 kb on - strand, within AO353_02300 at 490.000 kb on - strand, within AO353_02300 at 490.011 kb on + strand at 490.118 kb on - strand at 490.118 kb on - strand at 490.141 kb on - strand at 490.141 kb on - strand at 490.203 kb on + strand at 490.203 kb on + strand at 490.203 kb on + strand at 490.203 kb on + strand at 490.203 kb on + strand at 490.204 kb on - strand at 490.204 kb on - strand at 490.204 kb on - strand at 490.204 kb on - strand at 490.204 kb on - strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.205 kb on + strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.206 kb on - strand at 490.263 kb on - strand at 490.274 kb on + strand at 490.274 kb on + strand at 490.323 kb on + strand at 490.324 kb on - strand at 490.324 kb on - strand at 490.324 kb on - strand at 490.324 kb on - strand at 490.324 kb on - strand at 490.324 kb on - strand at 490.368 kb on + strand at 490.368 kb on + strand at 490.368 kb on + strand at 490.368 kb on + strand at 490.369 kb on - strand at 490.369 kb on - strand at 490.369 kb on - strand at 490.369 kb on - strand at 490.369 kb on - strand at 490.374 kb on + strand at 490.374 kb on + strand at 490.375 kb on - strand at 490.375 kb on - strand at 490.375 kb on - strand at 490.390 kb on + strand at 490.390 kb on + strand at 490.391 kb on - strand at 490.391 kb on - strand at 490.391 kb on - strand at 490.391 kb on - strand at 490.391 kb on - strand at 490.391 kb on - strand at 490.475 kb on + strand at 490.523 kb on + strand at 490.523 kb on + strand at 490.523 kb on + strand at 490.523 kb on + strand at 490.524 kb on - strand at 490.524 kb on - strand at 490.524 kb on - strand at 490.524 kb on - strand at 490.524 kb on - strand at 490.524 kb on - strand at 490.526 kb on + strand at 490.526 kb on + strand at 490.526 kb on + strand at 490.526 kb on + strand at 490.526 kb on + strand at 490.526 kb on + strand at 490.527 kb on - strand at 490.527 kb on - strand at 490.527 kb on - strand at 490.548 kb on + strand, within AO353_02305 at 490.548 kb on + strand at 490.548 kb on + strand, within AO353_02305 at 490.548 kb on + strand, within AO353_02305 at 490.548 kb on + strand, within AO353_02305 at 490.548 kb on + strand, within AO353_02305 at 490.548 kb on + strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.549 kb on - strand, within AO353_02305 at 490.659 kb on + strand, within AO353_02305 at 490.660 kb on - strand, within AO353_02305 at 490.660 kb on - strand, within AO353_02305 at 490.660 kb on - strand, within AO353_02305 at 490.712 kb on + strand, within AO353_02305 at 490.712 kb on + strand, within AO353_02305 at 490.713 kb on - strand, within AO353_02305 at 490.716 kb on + strand, within AO353_02305 at 490.716 kb on + strand, within AO353_02305 at 490.717 kb on - strand, within AO353_02305 at 490.717 kb on - strand, within AO353_02305 at 490.717 kb on - strand, within AO353_02305 at 490.717 kb on - strand, within AO353_02305 at 490.717 kb on - strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 490.835 kb on + strand, within AO353_02305 at 491.016 kb on + strand, within AO353_02305 at 491.016 kb on + strand, within AO353_02305 at 491.016 kb on + strand, within AO353_02305 at 491.016 kb on + strand, within AO353_02305 at 491.017 kb on - strand, within AO353_02305 at 491.094 kb on + strand, within AO353_02305 at 491.094 kb on + strand, within AO353_02305 at 491.094 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.364 kb on + strand, within AO353_02305 at 491.365 kb on - strand, within AO353_02305 at 491.365 kb on - strand, within AO353_02305 at 491.365 kb on - strand, within AO353_02305 at 491.386 kb on + strand, within AO353_02305 at 491.425 kb on + strand, within AO353_02305 at 491.425 kb on + strand, within AO353_02305 at 491.425 kb on + strand, within AO353_02305 at 491.425 kb on + strand, within AO353_02305 at 491.425 kb on + strand, within AO353_02305 at 491.425 kb on + strand, within AO353_02305 at 491.426 kb on - strand, within AO353_02305 at 491.426 kb on - strand, within AO353_02305 at 491.426 kb on - strand, within AO353_02305 at 491.426 kb on - strand, within AO353_02305 at 491.426 kb on - strand, within AO353_02305 at 491.426 kb on - strand, within AO353_02305 at 491.434 kb on + strand, within AO353_02305 at 491.434 kb on + strand, within AO353_02305 at 491.434 kb on + strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.435 kb on - strand, within AO353_02305 at 491.438 kb on + strand, within AO353_02305 at 491.439 kb on - strand, within AO353_02305 at 491.439 kb on - strand, within AO353_02305 at 491.508 kb on + strand, within AO353_02305 at 491.508 kb on + strand, within AO353_02305 at 491.508 kb on + strand, within AO353_02305 at 491.508 kb on + strand, within AO353_02305 at 491.508 kb on + strand, within AO353_02305 at 491.509 kb on - strand, within AO353_02305 at 491.642 kb on + strand at 491.642 kb on + strand at 491.649 kb on + strand at 491.649 kb on + strand at 491.649 kb on + strand at 491.649 kb on + strand at 491.649 kb on + strand at 491.650 kb on - strand at 491.650 kb on - strand at 491.650 kb on - strand at 491.650 kb on - strand at 491.650 kb on - strand at 491.650 kb on - strand at 491.675 kb on + strand at 491.745 kb on + strand at 491.746 kb on - strand at 491.746 kb on - strand at 491.746 kb on - strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.799 kb on + strand at 491.800 kb on - strand at 491.800 kb on - strand at 491.800 kb on - strand at 491.912 kb on + strand, within AO353_02310 at 491.912 kb on + strand, within AO353_02310 at 491.913 kb on - strand, within AO353_02310 at 491.913 kb on - strand, within AO353_02310 at 491.913 kb on - strand, within AO353_02310 at 491.913 kb on - strand, within AO353_02310 at 491.913 kb on - strand, within AO353_02310 at 491.931 kb on - strand, within AO353_02310 at 491.931 kb on - strand, within AO353_02310 at 491.952 kb on + strand, within AO353_02310 at 491.953 kb on - strand, within AO353_02310 at 491.953 kb on - strand, within AO353_02310 at 492.056 kb on + strand, within AO353_02310 at 492.057 kb on - strand, within AO353_02310 at 492.057 kb on - strand, within AO353_02310 at 492.065 kb on + strand, within AO353_02310 at 492.066 kb on - strand, within AO353_02310 at 492.465 kb on + strand at 492.465 kb on + strand at 492.466 kb on - strand at 492.466 kb on - strand at 492.466 kb on - strand at 492.466 kb on - strand at 492.503 kb on + strand at 492.503 kb on + strand at 492.503 kb on + strand at 492.503 kb on + strand at 492.503 kb on + strand at 492.503 kb on + strand at 492.504 kb on - strand at 492.504 kb on - strand at 492.504 kb on - strand at 492.529 kb on + strand at 492.529 kb on + strand at 492.529 kb on + strand at 492.529 kb on + strand at 492.529 kb on + strand at 492.530 kb on - strand at 492.530 kb on - strand at 492.530 kb on - strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.621 kb on + strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.622 kb on - strand at 492.623 kb on + strand at 492.623 kb on + strand at 492.623 kb on + strand at 492.624 kb on - strand at 492.647 kb on + strand at 492.647 kb on + strand at 492.647 kb on + strand at 492.647 kb on + strand at 492.647 kb on + strand at 492.648 kb on - strand at 492.648 kb on - strand at 492.648 kb on - strand at 492.648 kb on - strand at 492.648 kb on - strand at 492.648 kb on - strand at 492.648 kb on - strand at 492.664 kb on + strand at 492.665 kb on - strand at 492.665 kb on - strand at 492.676 kb on + strand at 492.686 kb on - strand at 492.686 kb on - strand at 492.686 kb on - strand at 492.686 kb on - strand at 492.692 kb on - strand at 492.692 kb on - strand at 492.719 kb on - strand, within AO353_02315
Per-strain Table
Position Strand Gene LocusTag Fraction L-Histidine (C) remove 489,499 - -1.5 489,499 - +0.2 489,560 + +2.8 489,571 - -0.3 489,585 - -0.6 489,602 + +0.6 489,603 - +0.3 489,622 + +0.2 489,889 + AO353_02300 0.63 -0.9 489,889 + AO353_02300 0.63 -2.1 489,889 + AO353_02300 0.63 +0.8 490,000 - AO353_02300 0.88 -0.6 490,000 - AO353_02300 0.88 -2.1 490,000 - AO353_02300 0.88 +0.1 490,000 - AO353_02300 0.88 +0.2 490,011 + -2.5 490,118 - +0.6 490,118 - +0.0 490,141 - +0.5 490,141 - +1.2 490,203 + +1.5 490,203 + +1.1 490,203 + -1.8 490,203 + +0.2 490,203 + +0.2 490,204 - +0.1 490,204 - -1.2 490,204 - -0.3 490,204 - +1.2 490,204 - -0.5 490,205 + -0.4 490,205 + +0.2 490,205 + +0.5 490,205 + -2.8 490,205 + -1.9 490,205 + -0.4 490,205 + +0.0 490,205 + -1.6 490,205 + -0.8 490,205 + -1.4 490,205 + -0.3 490,205 + -0.1 490,205 + +0.9 490,206 - +0.1 490,206 - -0.1 490,206 - +0.0 490,206 - -1.3 490,206 - +0.5 490,206 - -1.0 490,206 - +0.2 490,206 - +0.1 490,206 - -0.9 490,206 - +0.5 490,206 - -0.9 490,206 - -0.0 490,206 - -0.7 490,206 - -0.5 490,263 - +0.9 490,274 + +2.0 490,274 + +0.1 490,323 + +0.6 490,324 - +0.5 490,324 - +0.1 490,324 - +0.4 490,324 - +0.6 490,324 - -1.9 490,324 - +0.0 490,368 + +0.1 490,368 + -0.1 490,368 + -0.6 490,368 + +0.4 490,369 - +1.2 490,369 - -0.9 490,369 - -0.7 490,369 - -1.3 490,369 - +0.2 490,374 + -1.5 490,374 + -1.9 490,375 - -0.4 490,375 - -0.5 490,375 - -0.4 490,390 + -0.4 490,390 + -0.8 490,391 - -0.5 490,391 - -0.5 490,391 - -1.4 490,391 - +0.2 490,391 - -1.1 490,391 - +1.0 490,475 + +0.1 490,523 + +0.5 490,523 + +3.8 490,523 + +1.2 490,523 + +0.2 490,524 - -0.3 490,524 - -0.3 490,524 - +1.0 490,524 - -0.6 490,524 - -1.1 490,524 - +0.2 490,526 + -1.8 490,526 + +0.0 490,526 + +1.0 490,526 + -0.8 490,526 + +0.2 490,526 + -0.3 490,527 - +0.1 490,527 - -0.1 490,527 - -0.9 490,548 + AO353_02305 0.11 -0.4 490,548 + +1.2 490,548 + AO353_02305 0.11 +0.4 490,548 + AO353_02305 0.11 -0.4 490,548 + AO353_02305 0.11 +0.4 490,548 + AO353_02305 0.11 -0.5 490,548 + AO353_02305 0.11 +1.2 490,549 - AO353_02305 0.11 +1.2 490,549 - AO353_02305 0.11 -0.4 490,549 - AO353_02305 0.11 -1.2 490,549 - AO353_02305 0.11 +0.6 490,549 - AO353_02305 0.11 -0.0 490,549 - AO353_02305 0.11 -1.6 490,549 - AO353_02305 0.11 +0.8 490,549 - AO353_02305 0.11 -0.2 490,549 - AO353_02305 0.11 +0.1 490,659 + AO353_02305 0.19 +2.0 490,660 - AO353_02305 0.19 -0.2 490,660 - AO353_02305 0.19 -0.2 490,660 - AO353_02305 0.19 -0.9 490,712 + AO353_02305 0.23 -0.5 490,712 + AO353_02305 0.23 +0.0 490,713 - AO353_02305 0.23 -0.1 490,716 + AO353_02305 0.24 -0.7 490,716 + AO353_02305 0.24 +0.2 490,717 - AO353_02305 0.24 +0.2 490,717 - AO353_02305 0.24 +0.9 490,717 - AO353_02305 0.24 -0.2 490,717 - AO353_02305 0.24 -0.4 490,717 - AO353_02305 0.24 -0.6 490,835 + AO353_02305 0.32 -0.5 490,835 + AO353_02305 0.32 -1.2 490,835 + AO353_02305 0.32 -0.1 490,835 + AO353_02305 0.32 -1.1 490,835 + AO353_02305 0.32 +1.0 490,835 + AO353_02305 0.32 +0.1 490,835 + AO353_02305 0.32 +0.2 491,016 + AO353_02305 0.46 +2.1 491,016 + AO353_02305 0.46 +1.5 491,016 + AO353_02305 0.46 -1.6 491,016 + AO353_02305 0.46 -2.1 491,017 - AO353_02305 0.46 +1.0 491,094 + AO353_02305 0.52 +1.2 491,094 + AO353_02305 0.52 +1.2 491,094 + AO353_02305 0.52 -0.2 491,364 + AO353_02305 0.72 -0.1 491,364 + AO353_02305 0.72 +0.0 491,364 + AO353_02305 0.72 +0.0 491,364 + AO353_02305 0.72 -1.5 491,364 + AO353_02305 0.72 -0.8 491,364 + AO353_02305 0.72 +0.1 491,364 + AO353_02305 0.72 +2.5 491,364 + AO353_02305 0.72 -0.7 491,364 + AO353_02305 0.72 -1.2 491,365 - AO353_02305 0.72 -0.2 491,365 - AO353_02305 0.72 +0.4 491,365 - AO353_02305 0.72 -0.4 491,386 + AO353_02305 0.73 +1.0 491,425 + AO353_02305 0.76 -1.4 491,425 + AO353_02305 0.76 -0.4 491,425 + AO353_02305 0.76 +1.2 491,425 + AO353_02305 0.76 +0.2 491,425 + AO353_02305 0.76 +0.2 491,425 + AO353_02305 0.76 +0.9 491,426 - AO353_02305 0.76 +0.3 491,426 - AO353_02305 0.76 +1.5 491,426 - AO353_02305 0.76 -0.3 491,426 - AO353_02305 0.76 +0.5 491,426 - AO353_02305 0.76 -0.4 491,426 - AO353_02305 0.76 +0.2 491,434 + AO353_02305 0.77 +0.6 491,434 + AO353_02305 0.77 -0.2 491,434 + AO353_02305 0.77 -0.9 491,435 - AO353_02305 0.77 -0.0 491,435 - AO353_02305 0.77 -0.8 491,435 - AO353_02305 0.77 +0.8 491,435 - AO353_02305 0.77 -0.4 491,435 - AO353_02305 0.77 +0.8 491,435 - AO353_02305 0.77 -0.4 491,435 - AO353_02305 0.77 -1.2 491,435 - AO353_02305 0.77 -1.8 491,438 + AO353_02305 0.77 +0.3 491,439 - AO353_02305 0.77 -0.6 491,439 - AO353_02305 0.77 +0.1 491,508 + AO353_02305 0.82 -0.6 491,508 + AO353_02305 0.82 +2.2 491,508 + AO353_02305 0.82 -1.3 491,508 + AO353_02305 0.82 +0.6 491,508 + AO353_02305 0.82 -0.6 491,509 - AO353_02305 0.82 +1.0 491,642 + +1.4 491,642 + -0.4 491,649 + -0.4 491,649 + +0.4 491,649 + +0.5 491,649 + +0.7 491,649 + +0.8 491,650 - +1.6 491,650 - -1.3 491,650 - +0.2 491,650 - -0.0 491,650 - +1.2 491,650 - +0.5 491,675 + +0.4 491,745 + +0.5 491,746 - +0.8 491,746 - -0.2 491,746 - -0.4 491,799 + -1.8 491,799 + +0.5 491,799 + -0.9 491,799 + +0.5 491,799 + +0.5 491,799 + +0.2 491,799 + +0.6 491,799 + -1.1 491,800 - -0.4 491,800 - -0.4 491,800 - +0.8 491,912 + AO353_02310 0.16 +0.0 491,912 + AO353_02310 0.16 -0.7 491,913 - AO353_02310 0.16 +0.7 491,913 - AO353_02310 0.16 -0.4 491,913 - AO353_02310 0.16 +0.5 491,913 - AO353_02310 0.16 -1.1 491,913 - AO353_02310 0.16 +0.6 491,931 - AO353_02310 0.19 +0.8 491,931 - AO353_02310 0.19 +1.5 491,952 + AO353_02310 0.22 +2.2 491,953 - AO353_02310 0.22 -2.4 491,953 - AO353_02310 0.22 +0.7 492,056 + AO353_02310 0.39 -0.3 492,057 - AO353_02310 0.39 -0.3 492,057 - AO353_02310 0.39 -0.4 492,065 + AO353_02310 0.40 -0.5 492,066 - AO353_02310 0.40 -0.2 492,465 + +1.8 492,465 + -0.1 492,466 - -0.6 492,466 - +0.2 492,466 - +0.6 492,466 - +0.4 492,503 + -1.2 492,503 + +0.5 492,503 + +1.2 492,503 + -0.6 492,503 + -0.4 492,503 + -0.7 492,504 - +0.8 492,504 - +0.4 492,504 - -1.1 492,529 + -0.2 492,529 + -1.0 492,529 + +1.2 492,529 + -0.2 492,529 + +0.5 492,530 - -1.1 492,530 - -1.1 492,530 - -1.2 492,621 + -0.2 492,621 + +0.2 492,621 + -0.5 492,621 + +1.2 492,621 + -0.2 492,621 + -1.4 492,621 + -0.2 492,621 + -0.3 492,621 + +0.8 492,621 + +0.1 492,621 + +0.5 492,621 + +0.1 492,621 + -0.7 492,622 - +0.4 492,622 - +0.6 492,622 - +1.2 492,622 - +2.2 492,622 - -1.6 492,622 - -0.2 492,622 - -0.2 492,622 - -1.1 492,622 - +0.1 492,623 + -0.3 492,623 + -1.0 492,623 + +1.0 492,624 - -1.6 492,647 + -0.4 492,647 + +0.5 492,647 + -0.9 492,647 + -1.1 492,647 + -0.1 492,648 - +0.1 492,648 - +0.2 492,648 - +0.3 492,648 - -0.4 492,648 - -0.4 492,648 - +0.4 492,648 - +0.4 492,664 + +0.5 492,665 - -1.0 492,665 - +1.0 492,676 + -0.1 492,686 - +0.4 492,686 - +0.6 492,686 - +2.8 492,686 - -0.2 492,692 - +0.1 492,692 - +1.2 492,719 - AO353_02315 0.16 +0.5
Or see this region's nucleotide sequence