Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_651 and Pf1N1B4_652 are separated by 45 nucleotides Pf1N1B4_652 and Pf1N1B4_653 are separated by 2 nucleotides Pf1N1B4_653 and Pf1N1B4_654 are separated by 134 nucleotides
Pf1N1B4_651 - 2-dehydropantoate 2-reductase (EC 1.1.1.169), at 744,679 to 745,596
_651
Pf1N1B4_652 - Sensory box histidine kinase, at 745,642 to 747,678
_652
Pf1N1B4_653 - ATP:Cob(I)alamin adenosyltransferase (EC 2.5.1.17), at 747,681 to 748,262
_653
Pf1N1B4_654 - Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-) / Thiamin-phosphate pyrophosphorylase-like protein, at 748,397 to 749,341
_654
Position (kb)
745
746
747
748 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 744.696 kb on + strand at 744.696 kb on + strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.791 kb on + strand, within Pf1N1B4_651 at 744.792 kb on - strand, within Pf1N1B4_651 at 744.792 kb on - strand, within Pf1N1B4_651 at 744.792 kb on - strand at 744.850 kb on + strand, within Pf1N1B4_651 at 744.850 kb on + strand, within Pf1N1B4_651 at 744.903 kb on - strand, within Pf1N1B4_651 at 744.903 kb on - strand, within Pf1N1B4_651 at 744.919 kb on + strand, within Pf1N1B4_651 at 744.919 kb on + strand, within Pf1N1B4_651 at 745.114 kb on + strand, within Pf1N1B4_651 at 745.115 kb on - strand, within Pf1N1B4_651 at 745.182 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.439 kb on - strand, within Pf1N1B4_651 at 745.439 kb on - strand, within Pf1N1B4_651 at 745.477 kb on + strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.490 kb on - strand, within Pf1N1B4_651 at 745.629 kb on - strand at 745.747 kb on - strand at 745.759 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.763 kb on - strand at 745.763 kb on - strand at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.922 kb on - strand at 745.922 kb on - strand, within Pf1N1B4_652 at 745.922 kb on - strand, within Pf1N1B4_652 at 745.976 kb on + strand, within Pf1N1B4_652 at 746.113 kb on + strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.166 kb on - strand, within Pf1N1B4_652 at 746.260 kb on + strand, within Pf1N1B4_652 at 746.260 kb on + strand, within Pf1N1B4_652 at 746.261 kb on - strand, within Pf1N1B4_652 at 746.261 kb on - strand, within Pf1N1B4_652 at 746.261 kb on - strand, within Pf1N1B4_652 at 746.504 kb on - strand, within Pf1N1B4_652 at 746.504 kb on - strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.567 kb on + strand, within Pf1N1B4_652 at 746.756 kb on - strand, within Pf1N1B4_652 at 746.916 kb on + strand, within Pf1N1B4_652 at 746.916 kb on + strand, within Pf1N1B4_652 at 746.916 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.946 kb on - strand, within Pf1N1B4_652 at 747.037 kb on + strand at 747.038 kb on - strand, within Pf1N1B4_652 at 747.361 kb on - strand, within Pf1N1B4_652 at 747.396 kb on + strand, within Pf1N1B4_652 at 747.396 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.475 kb on - strand at 747.475 kb on - strand at 747.541 kb on + strand at 747.541 kb on + strand at 747.676 kb on + strand at 747.705 kb on + strand at 747.706 kb on - strand at 747.706 kb on - strand at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.945 kb on + strand, within Pf1N1B4_653 at 747.946 kb on - strand, within Pf1N1B4_653 at 747.946 kb on - strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.157 kb on + strand, within Pf1N1B4_653 at 748.157 kb on + strand, within Pf1N1B4_653 at 748.157 kb on + strand, within Pf1N1B4_653 at 748.158 kb on - strand, within Pf1N1B4_653 at 748.158 kb on - strand, within Pf1N1B4_653 at 748.260 kb on + strand at 748.320 kb on + strand at 748.508 kb on - strand, within Pf1N1B4_654 at 748.525 kb on + strand, within Pf1N1B4_654 at 748.525 kb on + strand, within Pf1N1B4_654 at 748.525 kb on + strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 744,696 + +1.0 744,696 + +1.0 744,697 - +2.5 744,697 - +0.0 744,697 - +0.3 744,697 - +2.0 744,697 - +1.4 744,697 - +0.2 744,697 - -1.6 744,791 + Pf1N1B4_651 0.12 -0.2 744,792 - Pf1N1B4_651 0.12 -0.2 744,792 - Pf1N1B4_651 0.12 +0.8 744,792 - +0.0 744,850 + Pf1N1B4_651 0.19 +0.5 744,850 + Pf1N1B4_651 0.19 +0.0 744,903 - Pf1N1B4_651 0.24 +1.5 744,903 - Pf1N1B4_651 0.24 -0.3 744,919 + Pf1N1B4_651 0.26 -1.8 744,919 + Pf1N1B4_651 0.26 +0.7 745,114 + Pf1N1B4_651 0.47 -0.5 745,115 - Pf1N1B4_651 0.47 -2.0 745,182 + Pf1N1B4_651 0.55 +0.4 745,438 + Pf1N1B4_651 0.83 -1.0 745,438 + Pf1N1B4_651 0.83 +0.9 745,438 + Pf1N1B4_651 0.83 +0.2 745,438 + Pf1N1B4_651 0.83 -0.7 745,439 - Pf1N1B4_651 0.83 +0.0 745,439 - Pf1N1B4_651 0.83 -2.6 745,477 + Pf1N1B4_651 0.87 +0.4 745,478 - Pf1N1B4_651 0.87 +0.6 745,478 - Pf1N1B4_651 0.87 +0.3 745,478 - Pf1N1B4_651 0.87 -1.8 745,478 - Pf1N1B4_651 0.87 -0.7 745,490 - Pf1N1B4_651 0.88 -0.1 745,629 - -0.2 745,747 - -0.4 745,759 + -0.4 745,762 + +1.0 745,762 + +1.6 745,762 + -2.0 745,762 + -2.3 745,762 + -1.0 745,762 + -1.3 745,762 + -0.8 745,763 - -2.1 745,763 - -1.0 745,894 + Pf1N1B4_652 0.12 -2.8 745,894 + -1.0 745,894 + Pf1N1B4_652 0.12 -3.0 745,894 + Pf1N1B4_652 0.12 -3.1 745,894 + Pf1N1B4_652 0.12 -2.6 745,894 + Pf1N1B4_652 0.12 -1.6 745,894 + Pf1N1B4_652 0.12 +0.0 745,895 - Pf1N1B4_652 0.12 -2.0 745,895 - Pf1N1B4_652 0.12 -1.1 745,895 - Pf1N1B4_652 0.12 -2.0 745,895 - Pf1N1B4_652 0.12 -1.6 745,895 - Pf1N1B4_652 0.12 +1.8 745,895 - Pf1N1B4_652 0.12 +0.0 745,896 + Pf1N1B4_652 0.12 +0.0 745,896 + Pf1N1B4_652 0.12 +0.6 745,896 + Pf1N1B4_652 0.12 -1.8 745,896 + Pf1N1B4_652 0.12 -0.2 745,896 + Pf1N1B4_652 0.12 -2.8 745,896 + -0.7 745,896 + Pf1N1B4_652 0.12 -0.7 745,896 + Pf1N1B4_652 0.12 -1.0 745,897 - Pf1N1B4_652 0.13 +1.4 745,897 - Pf1N1B4_652 0.13 -1.3 745,897 - Pf1N1B4_652 0.13 -2.0 745,897 - Pf1N1B4_652 0.13 -0.3 745,897 - -1.2 745,897 - Pf1N1B4_652 0.13 -2.6 745,897 - Pf1N1B4_652 0.13 -3.0 745,897 - Pf1N1B4_652 0.13 -2.2 745,897 - Pf1N1B4_652 0.13 -2.3 745,897 - +0.0 745,897 - Pf1N1B4_652 0.13 -2.1 745,897 - Pf1N1B4_652 0.13 +0.0 745,897 - Pf1N1B4_652 0.13 -0.3 745,921 + Pf1N1B4_652 0.14 -1.6 745,921 + Pf1N1B4_652 0.14 -1.0 745,921 + Pf1N1B4_652 0.14 +0.0 745,921 + Pf1N1B4_652 0.14 -2.6 745,922 - +0.0 745,922 - Pf1N1B4_652 0.14 -1.8 745,922 - Pf1N1B4_652 0.14 -1.6 745,976 + Pf1N1B4_652 0.16 +0.0 746,113 + Pf1N1B4_652 0.23 -2.6 746,114 - Pf1N1B4_652 0.23 -0.4 746,114 - Pf1N1B4_652 0.23 -1.8 746,114 - Pf1N1B4_652 0.23 +0.0 746,114 - Pf1N1B4_652 0.23 -1.3 746,166 - Pf1N1B4_652 0.26 -2.0 746,260 + Pf1N1B4_652 0.30 +0.0 746,260 + Pf1N1B4_652 0.30 +2.4 746,261 - Pf1N1B4_652 0.30 +1.8 746,261 - Pf1N1B4_652 0.30 -2.0 746,261 - Pf1N1B4_652 0.30 -0.6 746,504 - Pf1N1B4_652 0.42 +1.0 746,504 - Pf1N1B4_652 0.42 -2.0 746,563 + Pf1N1B4_652 0.45 -0.4 746,563 + Pf1N1B4_652 0.45 +0.7 746,563 + Pf1N1B4_652 0.45 -2.3 746,563 + Pf1N1B4_652 0.45 -0.7 746,563 + Pf1N1B4_652 0.45 +1.4 746,564 - Pf1N1B4_652 0.45 -3.0 746,564 - Pf1N1B4_652 0.45 -2.8 746,564 - Pf1N1B4_652 0.45 -1.2 746,564 - Pf1N1B4_652 0.45 -1.0 746,567 + Pf1N1B4_652 0.45 +0.6 746,756 - Pf1N1B4_652 0.55 -3.0 746,916 + Pf1N1B4_652 0.63 -1.7 746,916 + Pf1N1B4_652 0.63 -1.8 746,916 + Pf1N1B4_652 0.63 +0.0 746,945 + Pf1N1B4_652 0.64 +0.0 746,945 + Pf1N1B4_652 0.64 -1.1 746,945 + Pf1N1B4_652 0.64 +0.0 746,945 + Pf1N1B4_652 0.64 +0.8 746,946 - Pf1N1B4_652 0.64 -1.0 747,037 + -0.7 747,038 - Pf1N1B4_652 0.69 -3.6 747,361 - Pf1N1B4_652 0.84 -1.3 747,396 + Pf1N1B4_652 0.86 -3.0 747,396 + Pf1N1B4_652 0.86 -1.0 747,474 + Pf1N1B4_652 0.90 -0.3 747,474 + Pf1N1B4_652 0.90 -1.3 747,474 + Pf1N1B4_652 0.90 -1.3 747,474 + Pf1N1B4_652 0.90 -1.6 747,474 + Pf1N1B4_652 0.90 +0.0 747,474 + Pf1N1B4_652 0.90 -0.6 747,475 - -0.2 747,475 - -2.3 747,541 + -2.0 747,541 + -0.6 747,676 + -0.6 747,705 + +0.7 747,706 - -1.0 747,706 - +0.0 747,854 + Pf1N1B4_653 0.30 -0.5 747,854 + Pf1N1B4_653 0.30 -1.8 747,854 + Pf1N1B4_653 0.30 +0.1 747,854 + Pf1N1B4_653 0.30 -1.0 747,854 + Pf1N1B4_653 0.30 +1.0 747,854 + Pf1N1B4_653 0.30 +0.0 747,854 + Pf1N1B4_653 0.30 -0.5 747,854 + Pf1N1B4_653 0.30 +1.4 747,854 + Pf1N1B4_653 0.30 -1.0 747,855 - Pf1N1B4_653 0.30 -1.6 747,855 - Pf1N1B4_653 0.30 -0.4 747,855 - Pf1N1B4_653 0.30 +0.6 747,855 - Pf1N1B4_653 0.30 +0.0 747,858 + Pf1N1B4_653 0.30 +1.4 747,858 + Pf1N1B4_653 0.30 +0.0 747,858 + Pf1N1B4_653 0.30 +1.4 747,858 + Pf1N1B4_653 0.30 +1.4 747,945 + Pf1N1B4_653 0.45 -1.6 747,946 - Pf1N1B4_653 0.46 -1.6 747,946 - Pf1N1B4_653 0.46 -2.6 748,072 + Pf1N1B4_653 0.67 +0.4 748,072 + Pf1N1B4_653 0.67 +1.4 748,072 + Pf1N1B4_653 0.67 -0.3 748,072 + Pf1N1B4_653 0.67 -0.4 748,155 + Pf1N1B4_653 0.81 +0.0 748,155 + Pf1N1B4_653 0.81 -1.1 748,155 + Pf1N1B4_653 0.81 -0.3 748,155 + Pf1N1B4_653 0.81 -1.0 748,155 + Pf1N1B4_653 0.81 -2.3 748,155 + Pf1N1B4_653 0.81 -0.6 748,155 + Pf1N1B4_653 0.81 -1.6 748,156 - Pf1N1B4_653 0.82 +0.0 748,156 - Pf1N1B4_653 0.82 +0.3 748,156 - Pf1N1B4_653 0.82 +0.0 748,156 - Pf1N1B4_653 0.82 +0.2 748,157 + Pf1N1B4_653 0.82 +0.0 748,157 + Pf1N1B4_653 0.82 +0.6 748,157 + Pf1N1B4_653 0.82 +0.1 748,158 - Pf1N1B4_653 0.82 +0.0 748,158 - Pf1N1B4_653 0.82 -0.7 748,260 + -1.0 748,320 + +2.6 748,508 - Pf1N1B4_654 0.12 -0.4 748,525 + Pf1N1B4_654 0.14 -1.0 748,525 + Pf1N1B4_654 0.14 -1.0 748,525 + Pf1N1B4_654 0.14 +2.0 748,526 - Pf1N1B4_654 0.14 -0.6 748,526 - Pf1N1B4_654 0.14 +0.6 748,526 - Pf1N1B4_654 0.14 +3.0 748,526 - Pf1N1B4_654 0.14 -1.0
Or see this region's nucleotide sequence