Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_3711 and Pf1N1B4_3712 are separated by 146 nucleotides Pf1N1B4_3712 and Pf1N1B4_3713 overlap by 4 nucleotides Pf1N1B4_3713 and Pf1N1B4_3714 overlap by 4 nucleotides Pf1N1B4_3714 and Pf1N1B4_3715 are separated by 2 nucleotides
Pf1N1B4_3711 - Cobyric acid synthase (EC 6.3.5.10), at 4,119,580 to 4,121,073
_3711
Pf1N1B4_3712 - Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62), at 4,121,220 to 4,121,753
_3712
Pf1N1B4_3713 - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21), at 4,121,750 to 4,122,805
_3713
Pf1N1B4_3714 - Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73), at 4,122,802 to 4,123,377
_3714
Pf1N1B4_3715 - Cobalamin synthase, at 4,123,380 to 4,124,111
_3715
Position (kb)
4121
4122
4123 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 4120.894 kb on + strand, within Pf1N1B4_3711 at 4120.894 kb on + strand, within Pf1N1B4_3711 at 4120.894 kb on + strand, within Pf1N1B4_3711 at 4120.894 kb on + strand, within Pf1N1B4_3711 at 4120.894 kb on + strand, within Pf1N1B4_3711 at 4120.894 kb on + strand, within Pf1N1B4_3711 at 4120.895 kb on - strand, within Pf1N1B4_3711 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.307 kb on + strand, within Pf1N1B4_3712 at 4121.308 kb on - strand at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.308 kb on - strand, within Pf1N1B4_3712 at 4121.309 kb on + strand, within Pf1N1B4_3712 at 4121.309 kb on + strand, within Pf1N1B4_3712 at 4121.309 kb on + strand, within Pf1N1B4_3712 at 4121.309 kb on + strand, within Pf1N1B4_3712 at 4121.309 kb on + strand, within Pf1N1B4_3712 at 4121.309 kb on + strand, within Pf1N1B4_3712 at 4121.310 kb on - strand at 4121.310 kb on - strand, within Pf1N1B4_3712 at 4121.310 kb on - strand, within Pf1N1B4_3712 at 4121.310 kb on - strand, within Pf1N1B4_3712 at 4121.310 kb on - strand, within Pf1N1B4_3712 at 4121.310 kb on - strand, within Pf1N1B4_3712 at 4121.310 kb on - strand, within Pf1N1B4_3712 at 4121.311 kb on + strand, within Pf1N1B4_3712 at 4121.311 kb on + strand, within Pf1N1B4_3712 at 4121.311 kb on + strand, within Pf1N1B4_3712 at 4121.311 kb on + strand at 4121.311 kb on + strand, within Pf1N1B4_3712 at 4121.319 kb on + strand, within Pf1N1B4_3712 at 4121.319 kb on + strand at 4121.319 kb on + strand, within Pf1N1B4_3712 at 4121.319 kb on + strand, within Pf1N1B4_3712 at 4121.319 kb on + strand, within Pf1N1B4_3712 at 4121.319 kb on + strand at 4121.320 kb on - strand, within Pf1N1B4_3712 at 4121.320 kb on - strand, within Pf1N1B4_3712 at 4121.320 kb on - strand, within Pf1N1B4_3712 at 4121.320 kb on - strand at 4121.320 kb on - strand, within Pf1N1B4_3712 at 4121.320 kb on - strand, within Pf1N1B4_3712 at 4121.320 kb on - strand at 4121.646 kb on + strand, within Pf1N1B4_3712 at 4121.646 kb on + strand, within Pf1N1B4_3712 at 4121.832 kb on + strand at 4121.832 kb on + strand at 4121.832 kb on + strand at 4122.225 kb on + strand, within Pf1N1B4_3713 at 4122.225 kb on + strand at 4122.225 kb on + strand, within Pf1N1B4_3713 at 4122.226 kb on - strand, within Pf1N1B4_3713 at 4122.226 kb on - strand, within Pf1N1B4_3713 at 4122.433 kb on + strand, within Pf1N1B4_3713 at 4122.544 kb on + strand, within Pf1N1B4_3713 at 4122.545 kb on - strand at 4123.126 kb on + strand, within Pf1N1B4_3714 at 4123.126 kb on + strand, within Pf1N1B4_3714 at 4123.211 kb on - strand, within Pf1N1B4_3714 at 4123.736 kb on - strand at 4123.736 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 4,120,894 + Pf1N1B4_3711 0.88 -1.2 4,120,894 + Pf1N1B4_3711 0.88 -1.6 4,120,894 + Pf1N1B4_3711 0.88 +1.0 4,120,894 + Pf1N1B4_3711 0.88 -0.3 4,120,894 + Pf1N1B4_3711 0.88 +0.8 4,120,894 + Pf1N1B4_3711 0.88 +1.2 4,120,895 - Pf1N1B4_3711 0.88 +0.8 4,121,307 + Pf1N1B4_3712 0.16 -0.5 4,121,307 + Pf1N1B4_3712 0.16 +1.1 4,121,307 + Pf1N1B4_3712 0.16 -1.4 4,121,307 + Pf1N1B4_3712 0.16 -0.2 4,121,307 + Pf1N1B4_3712 0.16 -0.4 4,121,307 + -2.2 4,121,307 + Pf1N1B4_3712 0.16 -0.8 4,121,307 + Pf1N1B4_3712 0.16 +0.6 4,121,307 + Pf1N1B4_3712 0.16 -0.8 4,121,307 + Pf1N1B4_3712 0.16 +0.2 4,121,307 + Pf1N1B4_3712 0.16 +1.4 4,121,307 + Pf1N1B4_3712 0.16 +0.0 4,121,308 - +0.2 4,121,308 - Pf1N1B4_3712 0.16 -3.0 4,121,308 - Pf1N1B4_3712 0.16 +1.4 4,121,308 - Pf1N1B4_3712 0.16 -1.2 4,121,308 - Pf1N1B4_3712 0.16 -0.2 4,121,308 - Pf1N1B4_3712 0.16 -0.5 4,121,308 - Pf1N1B4_3712 0.16 +0.2 4,121,308 - Pf1N1B4_3712 0.16 -2.5 4,121,308 - Pf1N1B4_3712 0.16 +1.9 4,121,308 - Pf1N1B4_3712 0.16 +0.9 4,121,308 - Pf1N1B4_3712 0.16 -1.2 4,121,308 - Pf1N1B4_3712 0.16 +1.1 4,121,308 - Pf1N1B4_3712 0.16 -0.8 4,121,308 - Pf1N1B4_3712 0.16 -0.2 4,121,308 - Pf1N1B4_3712 0.16 -1.2 4,121,308 - Pf1N1B4_3712 0.16 -0.0 4,121,308 - Pf1N1B4_3712 0.16 -0.4 4,121,308 - Pf1N1B4_3712 0.16 -1.8 4,121,309 + Pf1N1B4_3712 0.17 -1.5 4,121,309 + Pf1N1B4_3712 0.17 +0.6 4,121,309 + Pf1N1B4_3712 0.17 +0.4 4,121,309 + Pf1N1B4_3712 0.17 -0.7 4,121,309 + Pf1N1B4_3712 0.17 -0.8 4,121,309 + Pf1N1B4_3712 0.17 -0.6 4,121,310 - -1.8 4,121,310 - Pf1N1B4_3712 0.17 -1.3 4,121,310 - Pf1N1B4_3712 0.17 -1.8 4,121,310 - Pf1N1B4_3712 0.17 +0.9 4,121,310 - Pf1N1B4_3712 0.17 +1.4 4,121,310 - Pf1N1B4_3712 0.17 +2.6 4,121,310 - Pf1N1B4_3712 0.17 -3.0 4,121,311 + Pf1N1B4_3712 0.17 -2.5 4,121,311 + Pf1N1B4_3712 0.17 +0.8 4,121,311 + Pf1N1B4_3712 0.17 +0.8 4,121,311 + +1.1 4,121,311 + Pf1N1B4_3712 0.17 +0.7 4,121,319 + Pf1N1B4_3712 0.19 -0.2 4,121,319 + -1.2 4,121,319 + Pf1N1B4_3712 0.19 +1.8 4,121,319 + Pf1N1B4_3712 0.19 -0.2 4,121,319 + Pf1N1B4_3712 0.19 +0.1 4,121,319 + +1.4 4,121,320 - Pf1N1B4_3712 0.19 -1.2 4,121,320 - Pf1N1B4_3712 0.19 -1.2 4,121,320 - Pf1N1B4_3712 0.19 -1.4 4,121,320 - -1.2 4,121,320 - Pf1N1B4_3712 0.19 +0.7 4,121,320 - Pf1N1B4_3712 0.19 +1.0 4,121,320 - -0.2 4,121,646 + Pf1N1B4_3712 0.80 -0.4 4,121,646 + Pf1N1B4_3712 0.80 +0.8 4,121,832 + +0.4 4,121,832 + -3.2 4,121,832 + +0.3 4,122,225 + Pf1N1B4_3713 0.45 -2.5 4,122,225 + +0.6 4,122,225 + Pf1N1B4_3713 0.45 -0.6 4,122,226 - Pf1N1B4_3713 0.45 +0.6 4,122,226 - Pf1N1B4_3713 0.45 -1.8 4,122,433 + Pf1N1B4_3713 0.65 -0.8 4,122,544 + Pf1N1B4_3713 0.75 -0.2 4,122,545 - +1.8 4,123,126 + Pf1N1B4_3714 0.56 -0.0 4,123,126 + Pf1N1B4_3714 0.56 +0.8 4,123,211 - Pf1N1B4_3714 0.71 +1.3 4,123,736 - -0.2 4,123,736 - +0.8
Or see this region's nucleotide sequence