Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_3481 and Pf1N1B4_3482 are separated by 147 nucleotides Pf1N1B4_3482 and Pf1N1B4_3483 are separated by 192 nucleotides Pf1N1B4_3483 and Pf1N1B4_3484 overlap by 4 nucleotides
Pf1N1B4_3481 - Dienelactone hydrolase family, at 3,888,284 to 3,889,075
_3481
Pf1N1B4_3482 - outer membrane protein H1, at 3,889,223 to 3,889,825
_3482
Pf1N1B4_3483 - Transcriptional regulatory protein PhoP, at 3,890,018 to 3,890,695
_3483
Pf1N1B4_3484 - Sensor protein PhoQ (EC 2.7.13.3), at 3,890,692 to 3,892,038
_3484
Position (kb)
3890
3891 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 3889.090 kb on - strand at 3889.090 kb on - strand at 3889.092 kb on + strand at 3889.092 kb on + strand at 3889.092 kb on + strand at 3889.092 kb on + strand at 3889.093 kb on - strand at 3889.093 kb on - strand at 3889.093 kb on - strand at 3889.093 kb on - strand at 3889.112 kb on + strand at 3889.112 kb on + strand at 3889.112 kb on + strand at 3889.112 kb on + strand at 3889.113 kb on - strand at 3889.113 kb on - strand at 3889.157 kb on + strand at 3889.173 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.201 kb on + strand at 3889.202 kb on - strand at 3889.202 kb on - strand at 3889.202 kb on - strand at 3889.202 kb on - strand at 3889.228 kb on + strand at 3889.229 kb on - strand at 3889.234 kb on + strand at 3889.235 kb on - strand at 3889.339 kb on + strand, within Pf1N1B4_3482 at 3889.454 kb on + strand, within Pf1N1B4_3482 at 3889.454 kb on + strand, within Pf1N1B4_3482 at 3889.454 kb on + strand, within Pf1N1B4_3482 at 3889.454 kb on + strand, within Pf1N1B4_3482 at 3889.454 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.463 kb on + strand, within Pf1N1B4_3482 at 3889.464 kb on - strand, within Pf1N1B4_3482 at 3889.464 kb on - strand, within Pf1N1B4_3482 at 3889.464 kb on - strand at 3889.495 kb on + strand, within Pf1N1B4_3482 at 3889.495 kb on + strand, within Pf1N1B4_3482 at 3889.495 kb on + strand, within Pf1N1B4_3482 at 3889.495 kb on + strand, within Pf1N1B4_3482 at 3889.495 kb on + strand, within Pf1N1B4_3482 at 3889.526 kb on + strand, within Pf1N1B4_3482 at 3889.526 kb on + strand, within Pf1N1B4_3482 at 3889.526 kb on + strand, within Pf1N1B4_3482 at 3889.526 kb on + strand, within Pf1N1B4_3482 at 3889.526 kb on + strand, within Pf1N1B4_3482 at 3889.526 kb on + strand, within Pf1N1B4_3482 at 3889.538 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.665 kb on + strand, within Pf1N1B4_3482 at 3889.712 kb on + strand, within Pf1N1B4_3482 at 3889.799 kb on + strand at 3889.799 kb on + strand at 3889.799 kb on + strand at 3889.799 kb on + strand at 3889.799 kb on + strand at 3889.799 kb on + strand at 3889.799 kb on + strand at 3889.800 kb on - strand at 3889.814 kb on + strand at 3889.814 kb on + strand at 3889.814 kb on + strand at 3889.814 kb on + strand at 3889.814 kb on + strand at 3889.823 kb on + strand at 3889.823 kb on + strand at 3889.823 kb on + strand at 3889.824 kb on - strand at 3889.824 kb on - strand at 3889.835 kb on + strand at 3889.835 kb on + strand at 3889.836 kb on - strand at 3889.980 kb on + strand at 3889.980 kb on + strand at 3889.980 kb on + strand at 3890.017 kb on + strand at 3890.129 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.309 kb on + strand, within Pf1N1B4_3483 at 3890.310 kb on - strand, within Pf1N1B4_3483 at 3890.475 kb on - strand, within Pf1N1B4_3483 at 3890.495 kb on + strand, within Pf1N1B4_3483 at 3890.495 kb on + strand, within Pf1N1B4_3483 at 3890.496 kb on - strand, within Pf1N1B4_3483 at 3890.496 kb on - strand, within Pf1N1B4_3483 at 3890.938 kb on + strand, within Pf1N1B4_3484 at 3890.938 kb on + strand, within Pf1N1B4_3484 at 3890.939 kb on - strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.944 kb on + strand, within Pf1N1B4_3484 at 3890.945 kb on - strand, within Pf1N1B4_3484 at 3891.004 kb on + strand, within Pf1N1B4_3484 at 3891.004 kb on + strand, within Pf1N1B4_3484 at 3891.079 kb on + strand, within Pf1N1B4_3484 at 3891.079 kb on + strand, within Pf1N1B4_3484 at 3891.079 kb on + strand, within Pf1N1B4_3484
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 3,889,090 - -0.8 3,889,090 - +0.6 3,889,092 + +1.5 3,889,092 + -0.1 3,889,092 + +1.5 3,889,092 + +0.9 3,889,093 - +0.8 3,889,093 - -0.1 3,889,093 - -0.1 3,889,093 - +1.1 3,889,112 + +0.7 3,889,112 + +0.3 3,889,112 + +0.8 3,889,112 + +0.3 3,889,113 - +0.0 3,889,113 - -1.1 3,889,157 + +1.1 3,889,173 + +0.6 3,889,201 + +1.4 3,889,201 + +0.3 3,889,201 + +0.6 3,889,201 + +1.3 3,889,201 + +0.3 3,889,201 + +1.2 3,889,201 + +0.3 3,889,201 + +1.5 3,889,201 + +0.5 3,889,201 + +0.5 3,889,201 + -0.6 3,889,201 + -2.7 3,889,201 + +2.1 3,889,201 + +1.0 3,889,201 + +0.9 3,889,201 + +0.8 3,889,202 - -0.2 3,889,202 - -0.1 3,889,202 - -1.4 3,889,202 - -0.8 3,889,228 + +0.2 3,889,229 - -0.5 3,889,234 + +1.8 3,889,235 - +0.5 3,889,339 + Pf1N1B4_3482 0.19 +0.4 3,889,454 + Pf1N1B4_3482 0.38 +0.0 3,889,454 + Pf1N1B4_3482 0.38 +1.2 3,889,454 + Pf1N1B4_3482 0.38 +0.5 3,889,454 + Pf1N1B4_3482 0.38 +1.2 3,889,454 + Pf1N1B4_3482 0.38 +1.1 3,889,463 + Pf1N1B4_3482 0.40 +0.9 3,889,463 + Pf1N1B4_3482 0.40 -0.2 3,889,463 + Pf1N1B4_3482 0.40 +1.2 3,889,463 + Pf1N1B4_3482 0.40 +1.7 3,889,463 + Pf1N1B4_3482 0.40 +3.4 3,889,463 + Pf1N1B4_3482 0.40 +2.1 3,889,463 + Pf1N1B4_3482 0.40 +1.4 3,889,463 + Pf1N1B4_3482 0.40 -0.9 3,889,463 + Pf1N1B4_3482 0.40 -0.0 3,889,463 + Pf1N1B4_3482 0.40 +0.4 3,889,463 + Pf1N1B4_3482 0.40 +1.3 3,889,464 - Pf1N1B4_3482 0.40 -0.5 3,889,464 - Pf1N1B4_3482 0.40 -0.1 3,889,464 - -1.3 3,889,495 + Pf1N1B4_3482 0.45 +0.7 3,889,495 + Pf1N1B4_3482 0.45 +1.4 3,889,495 + Pf1N1B4_3482 0.45 -0.1 3,889,495 + Pf1N1B4_3482 0.45 -1.1 3,889,495 + Pf1N1B4_3482 0.45 +0.2 3,889,526 + Pf1N1B4_3482 0.50 +1.1 3,889,526 + Pf1N1B4_3482 0.50 +0.8 3,889,526 + Pf1N1B4_3482 0.50 +2.8 3,889,526 + Pf1N1B4_3482 0.50 +0.1 3,889,526 + Pf1N1B4_3482 0.50 +1.6 3,889,526 + Pf1N1B4_3482 0.50 +1.1 3,889,538 + Pf1N1B4_3482 0.52 -0.1 3,889,665 + Pf1N1B4_3482 0.73 -2.9 3,889,665 + Pf1N1B4_3482 0.73 +0.6 3,889,665 + Pf1N1B4_3482 0.73 -0.8 3,889,665 + Pf1N1B4_3482 0.73 +0.8 3,889,665 + Pf1N1B4_3482 0.73 +0.7 3,889,665 + Pf1N1B4_3482 0.73 +1.1 3,889,665 + Pf1N1B4_3482 0.73 -1.1 3,889,712 + Pf1N1B4_3482 0.81 +1.1 3,889,799 + +0.5 3,889,799 + +1.9 3,889,799 + -0.8 3,889,799 + +1.1 3,889,799 + +1.1 3,889,799 + +0.6 3,889,799 + +3.0 3,889,800 - -2.4 3,889,814 + +0.7 3,889,814 + +3.4 3,889,814 + -0.4 3,889,814 + +0.7 3,889,814 + +0.9 3,889,823 + -1.7 3,889,823 + -0.4 3,889,823 + +1.2 3,889,824 - -1.4 3,889,824 - -1.7 3,889,835 + -0.7 3,889,835 + +0.2 3,889,836 - -1.9 3,889,980 + -0.1 3,889,980 + +0.9 3,889,980 + +0.4 3,890,017 + -2.4 3,890,129 + Pf1N1B4_3483 0.16 +0.9 3,890,309 + Pf1N1B4_3483 0.43 -2.9 3,890,309 + Pf1N1B4_3483 0.43 -0.1 3,890,309 + Pf1N1B4_3483 0.43 -2.7 3,890,309 + Pf1N1B4_3483 0.43 -2.4 3,890,309 + Pf1N1B4_3483 0.43 -4.0 3,890,309 + Pf1N1B4_3483 0.43 -0.1 3,890,309 + Pf1N1B4_3483 0.43 -3.2 3,890,310 - Pf1N1B4_3483 0.43 -2.2 3,890,475 - Pf1N1B4_3483 0.67 -0.7 3,890,495 + Pf1N1B4_3483 0.70 -1.3 3,890,495 + Pf1N1B4_3483 0.70 -2.9 3,890,496 - Pf1N1B4_3483 0.71 -2.0 3,890,496 - Pf1N1B4_3483 0.71 -0.9 3,890,938 + Pf1N1B4_3484 0.18 +0.3 3,890,938 + Pf1N1B4_3484 0.18 -1.1 3,890,939 - Pf1N1B4_3484 0.18 -1.5 3,890,944 + Pf1N1B4_3484 0.19 -0.5 3,890,944 + Pf1N1B4_3484 0.19 +0.9 3,890,944 + Pf1N1B4_3484 0.19 +0.2 3,890,944 + Pf1N1B4_3484 0.19 -0.8 3,890,944 + Pf1N1B4_3484 0.19 -0.1 3,890,944 + Pf1N1B4_3484 0.19 +0.6 3,890,944 + Pf1N1B4_3484 0.19 +0.3 3,890,944 + Pf1N1B4_3484 0.19 -1.7 3,890,944 + Pf1N1B4_3484 0.19 -0.1 3,890,945 - Pf1N1B4_3484 0.19 -2.4 3,891,004 + Pf1N1B4_3484 0.23 -0.3 3,891,004 + Pf1N1B4_3484 0.23 +1.1 3,891,079 + Pf1N1B4_3484 0.29 +0.7 3,891,079 + Pf1N1B4_3484 0.29 -0.9 3,891,079 + Pf1N1B4_3484 0.29 +1.5
Or see this region's nucleotide sequence