Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_1925 and Pf1N1B4_1926 are separated by 72 nucleotides Pf1N1B4_1926 and Pf1N1B4_1927 are separated by 44 nucleotides
Pf1N1B4_1925 - Two-component response regulator, at 2,201,388 to 2,202,107
_1925
Pf1N1B4_1926 - DNA gyrase subunit B (EC 5.99.1.3), at 2,202,180 to 2,204,558
_1926
Pf1N1B4_1927 - DNA recombination and repair protein RecF, at 2,204,603 to 2,205,706
_1927
Position (kb)
2202
2203
2204
2205 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 2201.280 kb on + strand at 2201.280 kb on + strand at 2201.280 kb on + strand at 2201.280 kb on + strand at 2201.280 kb on + strand at 2201.281 kb on - strand at 2201.281 kb on - strand at 2201.281 kb on - strand at 2201.281 kb on - strand at 2201.281 kb on - strand at 2201.281 kb on - strand at 2201.333 kb on + strand at 2201.364 kb on - strand at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.489 kb on + strand, within Pf1N1B4_1925 at 2201.490 kb on - strand, within Pf1N1B4_1925 at 2201.490 kb on - strand, within Pf1N1B4_1925 at 2201.490 kb on - strand, within Pf1N1B4_1925 at 2201.700 kb on + strand, within Pf1N1B4_1925 at 2201.700 kb on + strand, within Pf1N1B4_1925 at 2201.700 kb on + strand, within Pf1N1B4_1925 at 2201.701 kb on - strand, within Pf1N1B4_1925 at 2201.794 kb on + strand, within Pf1N1B4_1925 at 2201.794 kb on + strand, within Pf1N1B4_1925 at 2201.794 kb on + strand at 2201.794 kb on + strand, within Pf1N1B4_1925 at 2201.795 kb on - strand, within Pf1N1B4_1925 at 2201.795 kb on - strand, within Pf1N1B4_1925 at 2201.881 kb on - strand, within Pf1N1B4_1925 at 2201.934 kb on + strand, within Pf1N1B4_1925 at 2201.934 kb on + strand, within Pf1N1B4_1925 at 2201.935 kb on - strand, within Pf1N1B4_1925 at 2201.935 kb on - strand, within Pf1N1B4_1925 at 2201.935 kb on - strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.940 kb on + strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.941 kb on - strand, within Pf1N1B4_1925 at 2201.968 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.996 kb on + strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2201.997 kb on - strand, within Pf1N1B4_1925 at 2202.001 kb on - strand, within Pf1N1B4_1925 at 2202.060 kb on + strand at 2202.060 kb on + strand at 2202.060 kb on + strand at 2202.061 kb on - strand at 2202.061 kb on - strand at 2202.127 kb on - strand at 2202.142 kb on + strand at 2204.694 kb on - strand at 2204.694 kb on - strand at 2204.706 kb on - strand at 2204.706 kb on - strand at 2204.706 kb on - strand at 2204.706 kb on - strand at 2204.706 kb on - strand at 2204.706 kb on - strand at 2204.706 kb on - strand at 2204.714 kb on - strand, within Pf1N1B4_1927 at 2204.714 kb on - strand, within Pf1N1B4_1927 at 2204.714 kb on - strand, within Pf1N1B4_1927 at 2204.714 kb on - strand, within Pf1N1B4_1927 at 2204.717 kb on - strand, within Pf1N1B4_1927 at 2204.717 kb on - strand, within Pf1N1B4_1927 at 2204.717 kb on - strand, within Pf1N1B4_1927 at 2204.717 kb on - strand, within Pf1N1B4_1927 at 2204.733 kb on - strand, within Pf1N1B4_1927 at 2204.733 kb on - strand, within Pf1N1B4_1927 at 2204.733 kb on - strand, within Pf1N1B4_1927 at 2204.806 kb on - strand, within Pf1N1B4_1927 at 2204.806 kb on - strand, within Pf1N1B4_1927 at 2204.806 kb on - strand, within Pf1N1B4_1927 at 2204.806 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.810 kb on - strand, within Pf1N1B4_1927 at 2204.912 kb on - strand, within Pf1N1B4_1927 at 2204.912 kb on - strand, within Pf1N1B4_1927 at 2204.912 kb on - strand, within Pf1N1B4_1927 at 2204.927 kb on - strand, within Pf1N1B4_1927 at 2205.043 kb on - strand, within Pf1N1B4_1927 at 2205.043 kb on - strand, within Pf1N1B4_1927 at 2205.043 kb on - strand, within Pf1N1B4_1927 at 2205.043 kb on - strand, within Pf1N1B4_1927 at 2205.118 kb on - strand, within Pf1N1B4_1927 at 2205.118 kb on - strand, within Pf1N1B4_1927 at 2205.118 kb on - strand, within Pf1N1B4_1927 at 2205.118 kb on - strand, within Pf1N1B4_1927 at 2205.118 kb on - strand, within Pf1N1B4_1927 at 2205.138 kb on - strand, within Pf1N1B4_1927 at 2205.138 kb on - strand, within Pf1N1B4_1927 at 2205.200 kb on - strand, within Pf1N1B4_1927 at 2205.449 kb on + strand, within Pf1N1B4_1927 at 2205.449 kb on + strand, within Pf1N1B4_1927 at 2205.449 kb on + strand, within Pf1N1B4_1927 at 2205.502 kb on + strand, within Pf1N1B4_1927 at 2205.502 kb on + strand, within Pf1N1B4_1927 at 2205.503 kb on - strand, within Pf1N1B4_1927 at 2205.503 kb on - strand, within Pf1N1B4_1927 at 2205.503 kb on - strand, within Pf1N1B4_1927 at 2205.503 kb on - strand, within Pf1N1B4_1927 at 2205.503 kb on - strand, within Pf1N1B4_1927 at 2205.503 kb on - strand, within Pf1N1B4_1927 at 2205.534 kb on - strand, within Pf1N1B4_1927 at 2205.536 kb on + strand, within Pf1N1B4_1927 at 2205.536 kb on + strand, within Pf1N1B4_1927 at 2205.536 kb on + strand, within Pf1N1B4_1927 at 2205.537 kb on - strand, within Pf1N1B4_1927 at 2205.547 kb on + strand, within Pf1N1B4_1927
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 2,201,280 + -1.3 2,201,280 + -1.0 2,201,280 + +0.4 2,201,280 + -1.9 2,201,280 + -0.9 2,201,281 - -0.8 2,201,281 - -1.2 2,201,281 - +0.1 2,201,281 - -0.3 2,201,281 - -1.9 2,201,281 - +0.3 2,201,333 + -0.6 2,201,364 - -1.0 2,201,489 + Pf1N1B4_1925 0.14 -0.9 2,201,489 + Pf1N1B4_1925 0.14 -2.2 2,201,489 + Pf1N1B4_1925 0.14 +0.7 2,201,489 + Pf1N1B4_1925 0.14 -1.3 2,201,489 + Pf1N1B4_1925 0.14 +0.2 2,201,489 + Pf1N1B4_1925 0.14 -0.8 2,201,489 + Pf1N1B4_1925 0.14 -0.6 2,201,489 + Pf1N1B4_1925 0.14 -0.2 2,201,489 + Pf1N1B4_1925 0.14 +2.4 2,201,489 + Pf1N1B4_1925 0.14 -0.9 2,201,490 - Pf1N1B4_1925 0.14 -1.9 2,201,490 - Pf1N1B4_1925 0.14 +0.4 2,201,490 - Pf1N1B4_1925 0.14 -1.3 2,201,700 + Pf1N1B4_1925 0.43 +0.4 2,201,700 + Pf1N1B4_1925 0.43 -1.0 2,201,700 + Pf1N1B4_1925 0.43 +0.4 2,201,701 - Pf1N1B4_1925 0.43 +0.4 2,201,794 + Pf1N1B4_1925 0.56 -0.6 2,201,794 + Pf1N1B4_1925 0.56 +0.4 2,201,794 + +0.4 2,201,794 + Pf1N1B4_1925 0.56 +0.4 2,201,795 - Pf1N1B4_1925 0.57 -0.1 2,201,795 - Pf1N1B4_1925 0.57 -2.2 2,201,881 - Pf1N1B4_1925 0.68 +0.4 2,201,934 + Pf1N1B4_1925 0.76 -1.3 2,201,934 + Pf1N1B4_1925 0.76 -0.1 2,201,935 - Pf1N1B4_1925 0.76 +1.4 2,201,935 - Pf1N1B4_1925 0.76 +1.0 2,201,935 - Pf1N1B4_1925 0.76 -2.2 2,201,940 + Pf1N1B4_1925 0.77 -0.6 2,201,940 + Pf1N1B4_1925 0.77 -0.6 2,201,940 + Pf1N1B4_1925 0.77 +0.8 2,201,940 + Pf1N1B4_1925 0.77 -1.2 2,201,940 + Pf1N1B4_1925 0.77 -0.1 2,201,940 + Pf1N1B4_1925 0.77 -0.2 2,201,940 + Pf1N1B4_1925 0.77 +0.4 2,201,940 + Pf1N1B4_1925 0.77 +0.4 2,201,940 + Pf1N1B4_1925 0.77 -0.9 2,201,940 + Pf1N1B4_1925 0.77 -0.2 2,201,941 - Pf1N1B4_1925 0.77 +0.7 2,201,941 - Pf1N1B4_1925 0.77 +2.9 2,201,941 - Pf1N1B4_1925 0.77 +1.2 2,201,941 - Pf1N1B4_1925 0.77 -2.6 2,201,941 - Pf1N1B4_1925 0.77 +0.4 2,201,941 - Pf1N1B4_1925 0.77 -0.6 2,201,941 - Pf1N1B4_1925 0.77 +0.4 2,201,941 - Pf1N1B4_1925 0.77 +0.2 2,201,941 - Pf1N1B4_1925 0.77 +1.2 2,201,968 + Pf1N1B4_1925 0.81 -2.4 2,201,996 + Pf1N1B4_1925 0.84 -0.6 2,201,996 + Pf1N1B4_1925 0.84 +1.1 2,201,996 + Pf1N1B4_1925 0.84 +0.1 2,201,996 + Pf1N1B4_1925 0.84 +0.0 2,201,996 + Pf1N1B4_1925 0.84 -0.1 2,201,996 + Pf1N1B4_1925 0.84 -1.8 2,201,996 + Pf1N1B4_1925 0.84 +0.9 2,201,996 + Pf1N1B4_1925 0.84 +0.4 2,201,996 + Pf1N1B4_1925 0.84 +0.4 2,201,996 + Pf1N1B4_1925 0.84 -1.9 2,201,996 + Pf1N1B4_1925 0.84 -1.4 2,201,996 + Pf1N1B4_1925 0.84 -0.2 2,201,996 + Pf1N1B4_1925 0.84 +2.4 2,201,996 + Pf1N1B4_1925 0.84 -1.2 2,201,996 + Pf1N1B4_1925 0.84 +2.6 2,201,996 + Pf1N1B4_1925 0.84 -2.7 2,201,997 - Pf1N1B4_1925 0.85 -1.6 2,201,997 - Pf1N1B4_1925 0.85 +0.8 2,201,997 - Pf1N1B4_1925 0.85 +0.7 2,201,997 - Pf1N1B4_1925 0.85 -0.1 2,201,997 - Pf1N1B4_1925 0.85 +0.4 2,201,997 - Pf1N1B4_1925 0.85 +1.1 2,201,997 - Pf1N1B4_1925 0.85 +1.9 2,201,997 - Pf1N1B4_1925 0.85 +0.3 2,201,997 - Pf1N1B4_1925 0.85 +0.3 2,201,997 - Pf1N1B4_1925 0.85 +1.2 2,201,997 - Pf1N1B4_1925 0.85 -0.6 2,201,997 - Pf1N1B4_1925 0.85 +0.3 2,201,997 - Pf1N1B4_1925 0.85 -0.0 2,202,001 - Pf1N1B4_1925 0.85 -2.7 2,202,060 + +0.4 2,202,060 + +0.4 2,202,060 + -1.4 2,202,061 - -2.9 2,202,061 - +0.2 2,202,127 - -1.6 2,202,142 + -1.6 2,204,694 - -3.7 2,204,694 - -1.6 2,204,706 - -2.9 2,204,706 - -2.2 2,204,706 - -0.6 2,204,706 - +0.4 2,204,706 - -2.2 2,204,706 - -2.7 2,204,706 - +0.4 2,204,714 - Pf1N1B4_1927 0.10 -1.6 2,204,714 - Pf1N1B4_1927 0.10 -1.6 2,204,714 - Pf1N1B4_1927 0.10 -0.6 2,204,714 - Pf1N1B4_1927 0.10 -1.2 2,204,717 - Pf1N1B4_1927 0.10 +0.9 2,204,717 - Pf1N1B4_1927 0.10 -0.6 2,204,717 - Pf1N1B4_1927 0.10 -1.9 2,204,717 - Pf1N1B4_1927 0.10 -3.0 2,204,733 - Pf1N1B4_1927 0.12 -1.6 2,204,733 - Pf1N1B4_1927 0.12 -2.4 2,204,733 - Pf1N1B4_1927 0.12 -1.6 2,204,806 - Pf1N1B4_1927 0.18 -3.4 2,204,806 - Pf1N1B4_1927 0.18 -1.6 2,204,806 - Pf1N1B4_1927 0.18 -1.2 2,204,806 - Pf1N1B4_1927 0.18 -1.2 2,204,810 - Pf1N1B4_1927 0.19 -1.6 2,204,810 - Pf1N1B4_1927 0.19 -2.6 2,204,810 - Pf1N1B4_1927 0.19 -2.2 2,204,810 - Pf1N1B4_1927 0.19 -1.9 2,204,810 - Pf1N1B4_1927 0.19 -3.2 2,204,810 - Pf1N1B4_1927 0.19 -3.3 2,204,810 - Pf1N1B4_1927 0.19 -1.6 2,204,810 - Pf1N1B4_1927 0.19 -1.6 2,204,912 - Pf1N1B4_1927 0.28 -2.2 2,204,912 - Pf1N1B4_1927 0.28 -3.8 2,204,912 - Pf1N1B4_1927 0.28 -3.0 2,204,927 - Pf1N1B4_1927 0.29 -2.6 2,205,043 - Pf1N1B4_1927 0.40 -1.2 2,205,043 - Pf1N1B4_1927 0.40 -2.4 2,205,043 - Pf1N1B4_1927 0.40 +0.4 2,205,043 - Pf1N1B4_1927 0.40 +0.4 2,205,118 - Pf1N1B4_1927 0.47 +0.4 2,205,118 - Pf1N1B4_1927 0.47 -2.4 2,205,118 - Pf1N1B4_1927 0.47 -1.7 2,205,118 - Pf1N1B4_1927 0.47 +0.4 2,205,118 - Pf1N1B4_1927 0.47 -1.2 2,205,138 - Pf1N1B4_1927 0.48 -2.2 2,205,138 - Pf1N1B4_1927 0.48 -0.6 2,205,200 - Pf1N1B4_1927 0.54 -0.8 2,205,449 + Pf1N1B4_1927 0.77 -1.6 2,205,449 + Pf1N1B4_1927 0.77 -1.4 2,205,449 + Pf1N1B4_1927 0.77 -2.2 2,205,502 + Pf1N1B4_1927 0.81 -1.7 2,205,502 + Pf1N1B4_1927 0.81 -2.2 2,205,503 - Pf1N1B4_1927 0.82 -1.2 2,205,503 - Pf1N1B4_1927 0.82 -1.2 2,205,503 - Pf1N1B4_1927 0.82 -1.9 2,205,503 - Pf1N1B4_1927 0.82 -1.6 2,205,503 - Pf1N1B4_1927 0.82 -2.6 2,205,503 - Pf1N1B4_1927 0.82 -1.6 2,205,534 - Pf1N1B4_1927 0.84 -1.4 2,205,536 + Pf1N1B4_1927 0.85 -0.6 2,205,536 + Pf1N1B4_1927 0.85 -0.6 2,205,536 + Pf1N1B4_1927 0.85 -2.4 2,205,537 - Pf1N1B4_1927 0.85 -2.6 2,205,547 + Pf1N1B4_1927 0.86 -2.6
Or see this region's nucleotide sequence