Experiment: Cisplatin 0.005 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_477 and Ac3H11_478 overlap by 4 nucleotides Ac3H11_478 and Ac3H11_479 overlap by 2 nucleotides Ac3H11_479 and Ac3H11_480 are separated by 84 nucleotides
Ac3H11_477 - Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-), at 172,657 to 174,171
_477
Ac3H11_478 - Hydroxyacylglutathione hydrolase (EC 3.1.2.6), at 174,168 to 174,953
_478
Ac3H11_479 - FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-), at 174,952 to 175,809
_479
Ac3H11_480 - Ribonuclease HI (EC 3.1.26.4), at 175,894 to 176,343
_480
Position (kb) 174
175 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3
4 at 173.168 kb on - strand, within Ac3H11_477 at 173.168 kb on - strand, within Ac3H11_477 at 173.168 kb on - strand, within Ac3H11_477 at 173.168 kb on - strand, within Ac3H11_477 at 173.168 kb on - strand, within Ac3H11_477 at 173.168 kb on - strand, within Ac3H11_477 at 173.250 kb on - strand, within Ac3H11_477 at 173.250 kb on - strand, within Ac3H11_477 at 173.250 kb on - strand, within Ac3H11_477 at 173.348 kb on + strand, within Ac3H11_477 at 173.348 kb on + strand, within Ac3H11_477 at 173.349 kb on - strand, within Ac3H11_477 at 173.413 kb on + strand, within Ac3H11_477 at 173.413 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.435 kb on + strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.436 kb on - strand, within Ac3H11_477 at 173.471 kb on + strand, within Ac3H11_477 at 173.472 kb on - strand, within Ac3H11_477 at 173.541 kb on - strand, within Ac3H11_477 at 173.541 kb on - strand, within Ac3H11_477 at 173.541 kb on - strand, within Ac3H11_477 at 173.541 kb on - strand, within Ac3H11_477 at 173.594 kb on + strand, within Ac3H11_477 at 173.623 kb on + strand, within Ac3H11_477 at 173.623 kb on + strand, within Ac3H11_477 at 173.623 kb on + strand, within Ac3H11_477 at 173.623 kb on + strand, within Ac3H11_477 at 173.669 kb on + strand, within Ac3H11_477 at 173.669 kb on + strand, within Ac3H11_477 at 173.669 kb on + strand, within Ac3H11_477 at 173.670 kb on - strand, within Ac3H11_477 at 173.670 kb on - strand, within Ac3H11_477 at 173.670 kb on - strand, within Ac3H11_477 at 173.753 kb on + strand, within Ac3H11_477 at 173.754 kb on - strand, within Ac3H11_477 at 173.754 kb on - strand, within Ac3H11_477 at 173.819 kb on + strand, within Ac3H11_477 at 173.819 kb on + strand, within Ac3H11_477 at 173.852 kb on + strand, within Ac3H11_477 at 173.852 kb on + strand, within Ac3H11_477 at 173.853 kb on - strand, within Ac3H11_477 at 173.853 kb on - strand, within Ac3H11_477 at 173.870 kb on + strand, within Ac3H11_477 at 173.871 kb on - strand, within Ac3H11_477 at 173.871 kb on - strand, within Ac3H11_477 at 174.036 kb on + strand at 174.036 kb on + strand at 174.037 kb on - strand at 174.037 kb on - strand at 174.037 kb on - strand at 174.037 kb on - strand at 174.373 kb on + strand, within Ac3H11_478 at 174.374 kb on - strand, within Ac3H11_478 at 174.436 kb on + strand, within Ac3H11_478 at 174.436 kb on + strand, within Ac3H11_478 at 174.437 kb on - strand, within Ac3H11_478 at 174.437 kb on - strand, within Ac3H11_478 at 174.567 kb on + strand, within Ac3H11_478 at 174.567 kb on + strand, within Ac3H11_478 at 174.568 kb on - strand, within Ac3H11_478 at 174.568 kb on - strand, within Ac3H11_478 at 174.568 kb on - strand, within Ac3H11_478 at 174.568 kb on - strand, within Ac3H11_478 at 174.598 kb on + strand, within Ac3H11_478 at 174.598 kb on + strand, within Ac3H11_478 at 174.598 kb on + strand, within Ac3H11_478 at 174.598 kb on + strand, within Ac3H11_478 at 174.598 kb on + strand, within Ac3H11_478 at 174.599 kb on - strand, within Ac3H11_478 at 174.599 kb on - strand, within Ac3H11_478 at 174.599 kb on - strand, within Ac3H11_478 at 174.601 kb on + strand, within Ac3H11_478 at 174.601 kb on + strand, within Ac3H11_478 at 174.601 kb on + strand, within Ac3H11_478 at 174.601 kb on + strand, within Ac3H11_478 at 174.602 kb on - strand, within Ac3H11_478 at 174.602 kb on - strand, within Ac3H11_478 at 174.737 kb on - strand, within Ac3H11_478 at 174.767 kb on + strand, within Ac3H11_478 at 174.768 kb on - strand, within Ac3H11_478 at 174.768 kb on - strand, within Ac3H11_478 at 174.807 kb on + strand, within Ac3H11_478 at 174.807 kb on + strand, within Ac3H11_478 at 174.807 kb on + strand, within Ac3H11_478 at 174.807 kb on + strand, within Ac3H11_478 at 174.808 kb on - strand, within Ac3H11_478 at 174.808 kb on - strand, within Ac3H11_478 at 174.808 kb on - strand, within Ac3H11_478 at 174.808 kb on - strand, within Ac3H11_478 at 174.808 kb on - strand, within Ac3H11_478 at 174.808 kb on - strand, within Ac3H11_478 at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.916 kb on + strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.917 kb on - strand at 174.966 kb on + strand at 174.966 kb on + strand at 174.966 kb on + strand at 174.966 kb on + strand at 174.967 kb on - strand at 174.967 kb on - strand at 174.967 kb on - strand at 174.968 kb on + strand at 174.969 kb on - strand at 175.007 kb on - strand at 175.063 kb on + strand, within Ac3H11_479 at 175.064 kb on - strand, within Ac3H11_479 at 175.123 kb on + strand, within Ac3H11_479 at 175.124 kb on - strand, within Ac3H11_479 at 175.432 kb on + strand, within Ac3H11_479 at 175.459 kb on + strand, within Ac3H11_479 at 175.459 kb on + strand, within Ac3H11_479 at 175.459 kb on + strand, within Ac3H11_479 at 175.459 kb on + strand, within Ac3H11_479 at 175.649 kb on - strand, within Ac3H11_479 at 175.649 kb on - strand, within Ac3H11_479 at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.807 kb on + strand at 175.808 kb on - strand at 175.808 kb on - strand at 175.808 kb on - strand at 175.808 kb on - strand at 175.808 kb on - strand at 175.808 kb on - strand at 175.808 kb on - strand at 175.811 kb on + strand at 175.811 kb on + strand at 175.811 kb on + strand at 175.811 kb on + strand at 175.811 kb on + strand at 175.811 kb on + strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.812 kb on - strand at 175.904 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.005 mg/ml remove 173,168 - Ac3H11_477 0.34 +2.1 173,168 - Ac3H11_477 0.34 +2.4 173,168 - Ac3H11_477 0.34 +3.0 173,168 - Ac3H11_477 0.34 +0.7 173,168 - Ac3H11_477 0.34 +0.4 173,168 - Ac3H11_477 0.34 +2.9 173,250 - Ac3H11_477 0.39 +1.4 173,250 - Ac3H11_477 0.39 +0.7 173,250 - Ac3H11_477 0.39 -1.8 173,348 + Ac3H11_477 0.46 -2.1 173,348 + Ac3H11_477 0.46 -0.4 173,349 - Ac3H11_477 0.46 -3.3 173,413 + Ac3H11_477 0.50 -0.5 173,413 + Ac3H11_477 0.50 +1.6 173,435 + Ac3H11_477 0.51 +0.2 173,435 + Ac3H11_477 0.51 +3.3 173,435 + Ac3H11_477 0.51 -2.0 173,435 + Ac3H11_477 0.51 -0.5 173,435 + Ac3H11_477 0.51 +0.1 173,435 + Ac3H11_477 0.51 -0.4 173,435 + Ac3H11_477 0.51 -1.1 173,435 + Ac3H11_477 0.51 +1.4 173,435 + Ac3H11_477 0.51 -2.8 173,435 + Ac3H11_477 0.51 +1.4 173,435 + Ac3H11_477 0.51 -0.2 173,435 + Ac3H11_477 0.51 -1.2 173,435 + Ac3H11_477 0.51 -1.7 173,435 + Ac3H11_477 0.51 -0.9 173,435 + Ac3H11_477 0.51 -0.2 173,435 + Ac3H11_477 0.51 +0.3 173,435 + -0.4 173,435 + Ac3H11_477 0.51 -3.3 173,435 + Ac3H11_477 0.51 +0.2 173,435 + Ac3H11_477 0.51 +1.0 173,435 + Ac3H11_477 0.51 -2.4 173,435 + Ac3H11_477 0.51 -1.2 173,435 + Ac3H11_477 0.51 +2.2 173,435 + Ac3H11_477 0.51 +1.2 173,436 - Ac3H11_477 0.51 +1.0 173,436 - Ac3H11_477 0.51 -1.5 173,436 - Ac3H11_477 0.51 +1.4 173,436 - Ac3H11_477 0.51 -0.2 173,436 - Ac3H11_477 0.51 -1.1 173,436 - Ac3H11_477 0.51 -1.7 173,436 - Ac3H11_477 0.51 +0.0 173,436 - Ac3H11_477 0.51 +0.3 173,436 - Ac3H11_477 0.51 +1.3 173,436 - Ac3H11_477 0.51 +0.8 173,436 - Ac3H11_477 0.51 +0.8 173,436 - Ac3H11_477 0.51 -2.8 173,436 - Ac3H11_477 0.51 -3.3 173,436 - Ac3H11_477 0.51 +0.9 173,436 - Ac3H11_477 0.51 +1.6 173,436 - Ac3H11_477 0.51 -3.0 173,436 - Ac3H11_477 0.51 +0.6 173,436 - Ac3H11_477 0.51 -1.4 173,471 + Ac3H11_477 0.54 -2.0 173,472 - Ac3H11_477 0.54 -1.0 173,541 - Ac3H11_477 0.58 +0.1 173,541 - Ac3H11_477 0.58 +0.3 173,541 - Ac3H11_477 0.58 +0.8 173,541 - Ac3H11_477 0.58 +0.9 173,594 + Ac3H11_477 0.62 +0.4 173,623 + Ac3H11_477 0.64 +1.6 173,623 + Ac3H11_477 0.64 -0.1 173,623 + Ac3H11_477 0.64 -0.5 173,623 + Ac3H11_477 0.64 -1.2 173,669 + Ac3H11_477 0.67 -2.5 173,669 + Ac3H11_477 0.67 -1.9 173,669 + Ac3H11_477 0.67 -0.2 173,670 - Ac3H11_477 0.67 -0.4 173,670 - Ac3H11_477 0.67 +1.4 173,670 - Ac3H11_477 0.67 +0.3 173,753 + Ac3H11_477 0.72 -1.9 173,754 - Ac3H11_477 0.72 -1.7 173,754 - Ac3H11_477 0.72 -2.5 173,819 + Ac3H11_477 0.77 -2.9 173,819 + Ac3H11_477 0.77 -3.0 173,852 + Ac3H11_477 0.79 -0.2 173,852 + Ac3H11_477 0.79 -1.2 173,853 - Ac3H11_477 0.79 -2.9 173,853 - Ac3H11_477 0.79 +0.4 173,870 + Ac3H11_477 0.80 -3.0 173,871 - Ac3H11_477 0.80 +0.6 173,871 - Ac3H11_477 0.80 +1.4 174,036 + -1.8 174,036 + -2.4 174,037 - -3.0 174,037 - +3.0 174,037 - -0.1 174,037 - -0.4 174,373 + Ac3H11_478 0.26 -2.9 174,374 - Ac3H11_478 0.26 -0.8 174,436 + Ac3H11_478 0.34 +1.8 174,436 + Ac3H11_478 0.34 -0.8 174,437 - Ac3H11_478 0.34 +0.4 174,437 - Ac3H11_478 0.34 -1.1 174,567 + Ac3H11_478 0.51 -1.2 174,567 + Ac3H11_478 0.51 -1.8 174,568 - Ac3H11_478 0.51 -1.7 174,568 - Ac3H11_478 0.51 +0.9 174,568 - Ac3H11_478 0.51 +2.0 174,568 - Ac3H11_478 0.51 +1.0 174,598 + Ac3H11_478 0.55 +0.8 174,598 + Ac3H11_478 0.55 -1.5 174,598 + Ac3H11_478 0.55 -0.2 174,598 + Ac3H11_478 0.55 -1.0 174,598 + Ac3H11_478 0.55 +0.7 174,599 - Ac3H11_478 0.55 +0.2 174,599 - Ac3H11_478 0.55 -0.7 174,599 - Ac3H11_478 0.55 +1.8 174,601 + Ac3H11_478 0.55 +2.2 174,601 + Ac3H11_478 0.55 -0.5 174,601 + Ac3H11_478 0.55 +1.2 174,601 + Ac3H11_478 0.55 -2.5 174,602 - Ac3H11_478 0.55 +0.3 174,602 - Ac3H11_478 0.55 +1.1 174,737 - Ac3H11_478 0.72 -1.4 174,767 + Ac3H11_478 0.76 -1.5 174,768 - Ac3H11_478 0.76 +1.0 174,768 - Ac3H11_478 0.76 -0.9 174,807 + Ac3H11_478 0.81 -1.0 174,807 + Ac3H11_478 0.81 -2.7 174,807 + Ac3H11_478 0.81 -2.0 174,807 + Ac3H11_478 0.81 +1.5 174,808 - Ac3H11_478 0.81 -1.8 174,808 - Ac3H11_478 0.81 +0.8 174,808 - Ac3H11_478 0.81 +1.2 174,808 - Ac3H11_478 0.81 -2.5 174,808 - Ac3H11_478 0.81 -0.9 174,808 - Ac3H11_478 0.81 +1.8 174,916 + +0.4 174,916 + -0.0 174,916 + -2.3 174,916 + +4.3 174,916 + +1.5 174,916 + +1.1 174,916 + +2.3 174,916 + -1.0 174,916 + +0.0 174,917 - -1.0 174,917 - +0.6 174,917 - -1.8 174,917 - +1.3 174,917 - -1.8 174,917 - +0.9 174,917 - -0.2 174,917 - +2.0 174,917 - -0.6 174,917 - +0.3 174,966 + -1.5 174,966 + -1.9 174,966 + -0.2 174,966 + -0.5 174,967 - -1.4 174,967 - -2.5 174,967 - +0.0 174,968 + -0.9 174,969 - +0.5 175,007 - +0.6 175,063 + Ac3H11_479 0.13 -1.8 175,064 - Ac3H11_479 0.13 +1.5 175,123 + Ac3H11_479 0.20 -2.0 175,124 - Ac3H11_479 0.20 -0.5 175,432 + Ac3H11_479 0.56 -0.5 175,459 + Ac3H11_479 0.59 -3.0 175,459 + Ac3H11_479 0.59 -2.1 175,459 + Ac3H11_479 0.59 +0.4 175,459 + Ac3H11_479 0.59 -1.5 175,649 - Ac3H11_479 0.81 -1.7 175,649 - Ac3H11_479 0.81 -1.0 175,807 + -0.5 175,807 + -1.0 175,807 + +1.1 175,807 + +0.6 175,807 + -0.1 175,807 + +1.1 175,807 + -2.1 175,807 + +1.6 175,807 + +0.8 175,807 + -2.2 175,807 + +0.9 175,807 + -0.3 175,807 + +1.9 175,807 + +2.2 175,807 + +0.8 175,807 + -2.1 175,807 + +0.8 175,807 + -1.0 175,807 + -0.1 175,807 + -0.2 175,807 + -1.4 175,808 - +0.7 175,808 - +1.4 175,808 - +1.6 175,808 - +1.4 175,808 - -0.5 175,808 - +0.5 175,808 - +0.9 175,811 + +2.0 175,811 + +0.0 175,811 + -1.5 175,811 + +0.9 175,811 + +3.5 175,811 + +1.5 175,812 - -0.4 175,812 - +0.3 175,812 - -0.6 175,812 - +1.2 175,812 - -0.7 175,812 - -2.1 175,812 - +1.0 175,812 - -1.6 175,904 + -2.1
Or see this region's nucleotide sequence