Experiment: Cisplatin 0.005 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_4400 and Ac3H11_4401 are separated by 50 nucleotides Ac3H11_4401 and Ac3H11_4402 are separated by 175 nucleotides Ac3H11_4402 and Ac3H11_4403 overlap by 4 nucleotides
Ac3H11_4400 - putative LysR-family transcriptional regulator, at 196,833 to 197,729
_4400
Ac3H11_4401 - Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23), at 197,780 to 198,607
_4401
Ac3H11_4402 - Uracil-DNA glycosylase, family 1, at 198,783 to 199,340
_4402
Ac3H11_4403 - hypothetical protein, at 199,337 to 199,966
_4403
Position (kb)
197
198
199 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1
2
3 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.020 kb on + strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.021 kb on - strand, within Ac3H11_4400 at 197.026 kb on + strand, within Ac3H11_4400 at 197.026 kb on + strand, within Ac3H11_4400 at 197.027 kb on - strand, within Ac3H11_4400 at 197.027 kb on - strand, within Ac3H11_4400 at 197.134 kb on + strand, within Ac3H11_4400 at 197.135 kb on - strand, within Ac3H11_4400 at 197.135 kb on - strand, within Ac3H11_4400 at 197.143 kb on + strand, within Ac3H11_4400 at 197.290 kb on + strand, within Ac3H11_4400 at 197.290 kb on + strand, within Ac3H11_4400 at 197.290 kb on + strand, within Ac3H11_4400 at 197.291 kb on - strand, within Ac3H11_4400 at 197.291 kb on - strand, within Ac3H11_4400 at 197.782 kb on - strand at 197.868 kb on + strand, within Ac3H11_4401 at 197.868 kb on + strand, within Ac3H11_4401 at 197.868 kb on + strand, within Ac3H11_4401 at 197.868 kb on + strand, within Ac3H11_4401 at 197.868 kb on + strand, within Ac3H11_4401 at 197.869 kb on - strand, within Ac3H11_4401 at 197.869 kb on - strand, within Ac3H11_4401 at 197.869 kb on - strand, within Ac3H11_4401 at 197.869 kb on - strand, within Ac3H11_4401 at 197.869 kb on - strand, within Ac3H11_4401 at 197.869 kb on - strand, within Ac3H11_4401 at 198.099 kb on + strand, within Ac3H11_4401 at 198.099 kb on + strand, within Ac3H11_4401 at 198.100 kb on - strand, within Ac3H11_4401 at 198.201 kb on + strand, within Ac3H11_4401 at 198.486 kb on + strand, within Ac3H11_4401 at 198.486 kb on + strand, within Ac3H11_4401 at 198.486 kb on + strand, within Ac3H11_4401 at 198.486 kb on + strand, within Ac3H11_4401 at 198.487 kb on - strand, within Ac3H11_4401 at 198.487 kb on - strand, within Ac3H11_4401 at 198.487 kb on - strand, within Ac3H11_4401 at 198.668 kb on + strand at 198.668 kb on + strand at 198.669 kb on - strand at 198.669 kb on - strand at 198.669 kb on - strand at 198.669 kb on - strand at 198.710 kb on + strand at 198.739 kb on + strand at 198.739 kb on + strand at 198.739 kb on + strand at 198.740 kb on - strand at 198.835 kb on + strand at 198.835 kb on + strand at 198.836 kb on - strand at 198.836 kb on - strand at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.892 kb on + strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.893 kb on - strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.898 kb on + strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.899 kb on - strand, within Ac3H11_4402 at 198.916 kb on + strand, within Ac3H11_4402 at 198.917 kb on - strand, within Ac3H11_4402 at 198.917 kb on - strand, within Ac3H11_4402 at 198.917 kb on - strand, within Ac3H11_4402 at 198.917 kb on - strand, within Ac3H11_4402 at 198.917 kb on - strand, within Ac3H11_4402 at 199.072 kb on + strand, within Ac3H11_4402 at 199.072 kb on + strand, within Ac3H11_4402 at 199.073 kb on - strand, within Ac3H11_4402 at 199.073 kb on - strand, within Ac3H11_4402 at 199.073 kb on - strand, within Ac3H11_4402 at 199.073 kb on - strand, within Ac3H11_4402 at 199.246 kb on + strand, within Ac3H11_4402 at 199.246 kb on + strand, within Ac3H11_4402 at 199.246 kb on + strand, within Ac3H11_4402 at 199.246 kb on + strand, within Ac3H11_4402 at 199.246 kb on + strand, within Ac3H11_4402 at 199.247 kb on - strand, within Ac3H11_4402 at 199.371 kb on + strand at 199.371 kb on + strand at 199.371 kb on + strand at 199.372 kb on - strand at 199.372 kb on - strand at 199.372 kb on - strand at 199.372 kb on - strand at 199.372 kb on - strand at 199.372 kb on - strand at 199.372 kb on - strand at 199.413 kb on + strand, within Ac3H11_4403 at 199.413 kb on + strand, within Ac3H11_4403 at 199.413 kb on + strand, within Ac3H11_4403 at 199.414 kb on - strand, within Ac3H11_4403 at 199.414 kb on - strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.416 kb on + strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.417 kb on - strand, within Ac3H11_4403 at 199.440 kb on + strand, within Ac3H11_4403 at 199.440 kb on + strand, within Ac3H11_4403 at 199.440 kb on + strand, within Ac3H11_4403 at 199.440 kb on + strand, within Ac3H11_4403 at 199.441 kb on - strand, within Ac3H11_4403 at 199.441 kb on - strand, within Ac3H11_4403 at 199.441 kb on - strand, within Ac3H11_4403 at 199.518 kb on + strand, within Ac3H11_4403 at 199.518 kb on + strand, within Ac3H11_4403 at 199.519 kb on - strand, within Ac3H11_4403
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.005 mg/ml remove 197,020 + Ac3H11_4400 0.21 +1.0 197,020 + Ac3H11_4400 0.21 -1.5 197,020 + Ac3H11_4400 0.21 -2.5 197,020 + Ac3H11_4400 0.21 +1.1 197,020 + Ac3H11_4400 0.21 -1.5 197,020 + Ac3H11_4400 0.21 -4.5 197,020 + Ac3H11_4400 0.21 -4.0 197,020 + Ac3H11_4400 0.21 -1.0 197,020 + Ac3H11_4400 0.21 +2.7 197,020 + Ac3H11_4400 0.21 -0.8 197,020 + Ac3H11_4400 0.21 +1.9 197,020 + Ac3H11_4400 0.21 -2.3 197,020 + Ac3H11_4400 0.21 +0.5 197,021 - Ac3H11_4400 0.21 -0.6 197,021 - Ac3H11_4400 0.21 -2.1 197,021 - Ac3H11_4400 0.21 +0.6 197,021 - Ac3H11_4400 0.21 -1.3 197,021 - Ac3H11_4400 0.21 -3.4 197,021 - Ac3H11_4400 0.21 -2.7 197,021 - Ac3H11_4400 0.21 -1.0 197,021 - Ac3H11_4400 0.21 -1.0 197,021 - Ac3H11_4400 0.21 -0.3 197,021 - Ac3H11_4400 0.21 -0.3 197,026 + Ac3H11_4400 0.22 -1.1 197,026 + Ac3H11_4400 0.22 +0.8 197,027 - Ac3H11_4400 0.22 +0.5 197,027 - Ac3H11_4400 0.22 +1.9 197,134 + Ac3H11_4400 0.34 +1.2 197,135 - Ac3H11_4400 0.34 +0.1 197,135 - Ac3H11_4400 0.34 -0.1 197,143 + Ac3H11_4400 0.35 -0.8 197,290 + Ac3H11_4400 0.51 +0.7 197,290 + Ac3H11_4400 0.51 +2.5 197,290 + Ac3H11_4400 0.51 +1.9 197,291 - Ac3H11_4400 0.51 +1.0 197,291 - Ac3H11_4400 0.51 +0.7 197,782 - +1.9 197,868 + Ac3H11_4401 0.11 -4.4 197,868 + Ac3H11_4401 0.11 -2.7 197,868 + Ac3H11_4401 0.11 -4.9 197,868 + Ac3H11_4401 0.11 -2.6 197,868 + Ac3H11_4401 0.11 -3.7 197,869 - Ac3H11_4401 0.11 -5.2 197,869 - Ac3H11_4401 0.11 -2.9 197,869 - Ac3H11_4401 0.11 -1.5 197,869 - Ac3H11_4401 0.11 -0.3 197,869 - Ac3H11_4401 0.11 -1.5 197,869 - Ac3H11_4401 0.11 -0.9 198,099 + Ac3H11_4401 0.39 -2.5 198,099 + Ac3H11_4401 0.39 -3.3 198,100 - Ac3H11_4401 0.39 -1.1 198,201 + Ac3H11_4401 0.51 -4.1 198,486 + Ac3H11_4401 0.85 -3.5 198,486 + Ac3H11_4401 0.85 -3.2 198,486 + Ac3H11_4401 0.85 -2.0 198,486 + Ac3H11_4401 0.85 -0.9 198,487 - Ac3H11_4401 0.85 -1.7 198,487 - Ac3H11_4401 0.85 -2.0 198,487 - Ac3H11_4401 0.85 -1.7 198,668 + -3.8 198,668 + -1.6 198,669 - +1.6 198,669 - +1.1 198,669 - +0.9 198,669 - +0.6 198,710 + -1.2 198,739 + -0.7 198,739 + +1.2 198,739 + +1.3 198,740 - -1.7 198,835 + -0.0 198,835 + +2.0 198,836 - -2.9 198,836 - +1.8 198,892 + Ac3H11_4402 0.20 -0.3 198,892 + Ac3H11_4402 0.20 +2.2 198,892 + Ac3H11_4402 0.20 -0.4 198,892 + Ac3H11_4402 0.20 +1.2 198,892 + Ac3H11_4402 0.20 -0.3 198,892 + +0.1 198,892 + Ac3H11_4402 0.20 -1.1 198,892 + Ac3H11_4402 0.20 +0.3 198,892 + Ac3H11_4402 0.20 +2.0 198,892 + Ac3H11_4402 0.20 -0.1 198,892 + Ac3H11_4402 0.20 -2.3 198,892 + Ac3H11_4402 0.20 +0.9 198,892 + Ac3H11_4402 0.20 +3.6 198,892 + Ac3H11_4402 0.20 +0.2 198,892 + Ac3H11_4402 0.20 +0.5 198,892 + Ac3H11_4402 0.20 -1.1 198,893 - Ac3H11_4402 0.20 -0.8 198,893 - Ac3H11_4402 0.20 -1.4 198,893 - Ac3H11_4402 0.20 +0.2 198,893 - Ac3H11_4402 0.20 +0.7 198,893 - Ac3H11_4402 0.20 +2.6 198,893 - Ac3H11_4402 0.20 -2.3 198,893 - Ac3H11_4402 0.20 +0.1 198,893 - Ac3H11_4402 0.20 +0.7 198,893 - Ac3H11_4402 0.20 +0.4 198,893 - Ac3H11_4402 0.20 -2.5 198,893 - Ac3H11_4402 0.20 +1.6 198,893 - Ac3H11_4402 0.20 -0.4 198,893 - Ac3H11_4402 0.20 +1.3 198,893 - Ac3H11_4402 0.20 +1.2 198,893 - Ac3H11_4402 0.20 -0.1 198,893 - Ac3H11_4402 0.20 +0.6 198,893 - Ac3H11_4402 0.20 +0.8 198,893 - Ac3H11_4402 0.20 -1.2 198,893 - Ac3H11_4402 0.20 +1.2 198,893 - Ac3H11_4402 0.20 +1.6 198,898 + Ac3H11_4402 0.21 +2.3 198,898 + Ac3H11_4402 0.21 -0.7 198,898 + Ac3H11_4402 0.21 -0.6 198,898 + Ac3H11_4402 0.21 +3.0 198,898 + Ac3H11_4402 0.21 -2.2 198,898 + Ac3H11_4402 0.21 -0.5 198,898 + Ac3H11_4402 0.21 +0.3 198,898 + Ac3H11_4402 0.21 -2.6 198,898 + Ac3H11_4402 0.21 -0.6 198,898 + Ac3H11_4402 0.21 +0.8 198,898 + Ac3H11_4402 0.21 +2.5 198,898 + Ac3H11_4402 0.21 -0.3 198,898 + Ac3H11_4402 0.21 +1.0 198,898 + Ac3H11_4402 0.21 +0.6 198,898 + Ac3H11_4402 0.21 +0.9 198,898 + Ac3H11_4402 0.21 +0.7 198,898 + Ac3H11_4402 0.21 +0.9 198,898 + Ac3H11_4402 0.21 -2.8 198,898 + Ac3H11_4402 0.21 +1.1 198,898 + Ac3H11_4402 0.21 -0.8 198,899 - Ac3H11_4402 0.21 -0.0 198,899 - Ac3H11_4402 0.21 +0.2 198,899 - Ac3H11_4402 0.21 -1.1 198,899 - Ac3H11_4402 0.21 +2.4 198,899 - Ac3H11_4402 0.21 +0.9 198,899 - Ac3H11_4402 0.21 -2.5 198,899 - Ac3H11_4402 0.21 +0.6 198,899 - Ac3H11_4402 0.21 +0.7 198,899 - Ac3H11_4402 0.21 -2.7 198,899 - Ac3H11_4402 0.21 -0.3 198,899 - Ac3H11_4402 0.21 +2.2 198,916 + Ac3H11_4402 0.24 +0.7 198,917 - Ac3H11_4402 0.24 +1.8 198,917 - Ac3H11_4402 0.24 -2.6 198,917 - Ac3H11_4402 0.24 -1.9 198,917 - Ac3H11_4402 0.24 +1.0 198,917 - Ac3H11_4402 0.24 +1.2 199,072 + Ac3H11_4402 0.52 -0.0 199,072 + Ac3H11_4402 0.52 -0.1 199,073 - Ac3H11_4402 0.52 -3.0 199,073 - Ac3H11_4402 0.52 -3.6 199,073 - Ac3H11_4402 0.52 +2.5 199,073 - Ac3H11_4402 0.52 -1.8 199,246 + Ac3H11_4402 0.83 -0.0 199,246 + Ac3H11_4402 0.83 +1.6 199,246 + Ac3H11_4402 0.83 -2.9 199,246 + Ac3H11_4402 0.83 -2.7 199,246 + Ac3H11_4402 0.83 +1.0 199,247 - Ac3H11_4402 0.83 +2.3 199,371 + -0.6 199,371 + +1.2 199,371 + -2.5 199,372 - -1.6 199,372 - +2.7 199,372 - -0.2 199,372 - +2.5 199,372 - -0.7 199,372 - +0.3 199,372 - -2.1 199,413 + Ac3H11_4403 0.12 +1.2 199,413 + Ac3H11_4403 0.12 +2.2 199,413 + Ac3H11_4403 0.12 -1.1 199,414 - Ac3H11_4403 0.12 -1.7 199,414 - Ac3H11_4403 0.12 +0.6 199,416 + Ac3H11_4403 0.13 -0.0 199,416 + Ac3H11_4403 0.13 -1.3 199,416 + Ac3H11_4403 0.13 -2.9 199,416 + Ac3H11_4403 0.13 +0.8 199,416 + Ac3H11_4403 0.13 +0.4 199,416 + Ac3H11_4403 0.13 +0.7 199,416 + Ac3H11_4403 0.13 +1.1 199,416 + Ac3H11_4403 0.13 +0.3 199,416 + Ac3H11_4403 0.13 -2.5 199,416 + Ac3H11_4403 0.13 -0.7 199,416 + Ac3H11_4403 0.13 -0.3 199,416 + Ac3H11_4403 0.13 -3.1 199,417 - Ac3H11_4403 0.13 +1.1 199,417 - Ac3H11_4403 0.13 +1.0 199,417 - Ac3H11_4403 0.13 -3.7 199,417 - Ac3H11_4403 0.13 -0.4 199,417 - Ac3H11_4403 0.13 -3.5 199,417 - Ac3H11_4403 0.13 +1.1 199,417 - Ac3H11_4403 0.13 +0.9 199,417 - Ac3H11_4403 0.13 +2.3 199,417 - Ac3H11_4403 0.13 +1.5 199,417 - Ac3H11_4403 0.13 -2.7 199,417 - Ac3H11_4403 0.13 -1.5 199,417 - Ac3H11_4403 0.13 -2.5 199,440 + Ac3H11_4403 0.16 -2.2 199,440 + Ac3H11_4403 0.16 -0.9 199,440 + Ac3H11_4403 0.16 +0.8 199,440 + Ac3H11_4403 0.16 +0.2 199,441 - Ac3H11_4403 0.17 -0.9 199,441 - Ac3H11_4403 0.17 -3.0 199,441 - Ac3H11_4403 0.17 -0.8 199,518 + Ac3H11_4403 0.29 +2.9 199,518 + Ac3H11_4403 0.29 +1.2 199,519 - Ac3H11_4403 0.29 +1.0
Or see this region's nucleotide sequence