Experiment: Cisplatin 0.005 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_4373 and Ac3H11_4374 are separated by 415 nucleotides Ac3H11_4374 and Ac3H11_4375 overlap by 4 nucleotides Ac3H11_4375 and Ac3H11_4376 overlap by 4 nucleotides
Ac3H11_4373 - conserved hypothetical protein, at 162,345 to 162,821
_4373
Ac3H11_4374 - hypothetical protein, at 163,237 to 163,473
_4374
Ac3H11_4375 - Cellulose synthase, putative, at 163,470 to 164,252
_4375
Ac3H11_4376 - Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12), at 164,249 to 166,444
_4376
Position (kb)
163
164
165 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3
4 at 162.721 kb on - strand, within Ac3H11_4373 at 162.854 kb on - strand at 162.928 kb on + strand at 162.986 kb on + strand at 162.986 kb on + strand at 162.986 kb on + strand at 162.986 kb on + strand at 162.986 kb on + strand at 162.987 kb on - strand at 162.987 kb on - strand at 162.987 kb on - strand at 162.987 kb on - strand at 163.247 kb on + strand at 163.247 kb on + strand at 163.247 kb on + strand at 163.670 kb on + strand, within Ac3H11_4375 at 163.670 kb on + strand, within Ac3H11_4375 at 163.671 kb on - strand, within Ac3H11_4375 at 163.722 kb on + strand, within Ac3H11_4375 at 163.722 kb on + strand, within Ac3H11_4375 at 163.804 kb on + strand, within Ac3H11_4375 at 163.804 kb on + strand, within Ac3H11_4375 at 163.804 kb on + strand, within Ac3H11_4375 at 163.804 kb on + strand, within Ac3H11_4375 at 163.804 kb on + strand, within Ac3H11_4375 at 163.804 kb on + strand, within Ac3H11_4375 at 163.805 kb on - strand, within Ac3H11_4375 at 163.805 kb on - strand, within Ac3H11_4375 at 163.867 kb on - strand, within Ac3H11_4375 at 163.867 kb on - strand, within Ac3H11_4375 at 163.932 kb on + strand, within Ac3H11_4375 at 163.932 kb on + strand, within Ac3H11_4375 at 163.932 kb on + strand, within Ac3H11_4375 at 163.933 kb on - strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.967 kb on + strand, within Ac3H11_4375 at 163.968 kb on - strand, within Ac3H11_4375 at 163.968 kb on - strand, within Ac3H11_4375 at 163.968 kb on - strand, within Ac3H11_4375 at 163.968 kb on - strand, within Ac3H11_4375 at 163.971 kb on + strand, within Ac3H11_4375 at 163.971 kb on + strand, within Ac3H11_4375 at 163.971 kb on + strand, within Ac3H11_4375 at 163.971 kb on + strand, within Ac3H11_4375 at 163.971 kb on + strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 163.972 kb on - strand, within Ac3H11_4375 at 164.137 kb on - strand, within Ac3H11_4375 at 164.137 kb on - strand, within Ac3H11_4375 at 164.137 kb on - strand, within Ac3H11_4375 at 164.157 kb on + strand, within Ac3H11_4375 at 164.559 kb on - strand, within Ac3H11_4376 at 164.559 kb on - strand, within Ac3H11_4376 at 164.559 kb on - strand, within Ac3H11_4376 at 164.559 kb on - strand, within Ac3H11_4376 at 164.564 kb on + strand, within Ac3H11_4376 at 164.564 kb on + strand, within Ac3H11_4376 at 164.564 kb on + strand, within Ac3H11_4376 at 164.564 kb on + strand, within Ac3H11_4376 at 164.645 kb on + strand, within Ac3H11_4376 at 164.645 kb on + strand, within Ac3H11_4376 at 164.645 kb on + strand, within Ac3H11_4376 at 164.645 kb on + strand, within Ac3H11_4376 at 164.646 kb on - strand, within Ac3H11_4376 at 164.646 kb on - strand, within Ac3H11_4376 at 164.646 kb on - strand, within Ac3H11_4376 at 164.673 kb on - strand, within Ac3H11_4376 at 164.765 kb on + strand, within Ac3H11_4376 at 164.765 kb on + strand, within Ac3H11_4376 at 164.766 kb on - strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.846 kb on + strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.847 kb on - strand, within Ac3H11_4376 at 164.909 kb on + strand, within Ac3H11_4376 at 164.909 kb on + strand, within Ac3H11_4376 at 164.910 kb on - strand, within Ac3H11_4376 at 164.984 kb on + strand, within Ac3H11_4376 at 164.984 kb on + strand, within Ac3H11_4376 at 164.985 kb on - strand, within Ac3H11_4376 at 164.985 kb on - strand, within Ac3H11_4376 at 164.985 kb on - strand, within Ac3H11_4376 at 165.167 kb on + strand, within Ac3H11_4376
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.005 mg/ml remove 162,721 - Ac3H11_4373 0.79 +1.2 162,854 - +1.4 162,928 + +1.9 162,986 + +2.1 162,986 + +2.0 162,986 + +2.2 162,986 + +1.0 162,986 + +2.3 162,987 - +2.3 162,987 - +1.8 162,987 - +2.2 162,987 - -0.3 163,247 + -0.3 163,247 + +1.7 163,247 + +2.8 163,670 + Ac3H11_4375 0.26 +1.1 163,670 + Ac3H11_4375 0.26 +2.0 163,671 - Ac3H11_4375 0.26 +0.4 163,722 + Ac3H11_4375 0.32 +2.3 163,722 + Ac3H11_4375 0.32 +2.6 163,804 + Ac3H11_4375 0.43 +1.6 163,804 + Ac3H11_4375 0.43 +1.8 163,804 + Ac3H11_4375 0.43 +2.6 163,804 + Ac3H11_4375 0.43 -0.3 163,804 + Ac3H11_4375 0.43 -0.4 163,804 + Ac3H11_4375 0.43 +1.6 163,805 - Ac3H11_4375 0.43 +2.7 163,805 - Ac3H11_4375 0.43 +0.0 163,867 - Ac3H11_4375 0.51 +1.4 163,867 - Ac3H11_4375 0.51 -2.0 163,932 + Ac3H11_4375 0.59 +2.4 163,932 + Ac3H11_4375 0.59 +0.1 163,932 + Ac3H11_4375 0.59 +1.7 163,933 - Ac3H11_4375 0.59 +3.1 163,967 + Ac3H11_4375 0.63 +0.8 163,967 + Ac3H11_4375 0.63 +2.2 163,967 + Ac3H11_4375 0.63 +1.6 163,967 + Ac3H11_4375 0.63 +1.6 163,967 + Ac3H11_4375 0.63 +1.1 163,967 + Ac3H11_4375 0.63 +1.0 163,967 + Ac3H11_4375 0.63 -1.8 163,967 + Ac3H11_4375 0.63 +2.8 163,967 + Ac3H11_4375 0.63 +1.8 163,967 + Ac3H11_4375 0.63 +1.0 163,967 + Ac3H11_4375 0.63 +2.5 163,967 + Ac3H11_4375 0.63 -2.3 163,967 + Ac3H11_4375 0.63 +0.6 163,967 + Ac3H11_4375 0.63 -4.2 163,967 + Ac3H11_4375 0.63 +1.6 163,967 + Ac3H11_4375 0.63 -0.5 163,968 - Ac3H11_4375 0.64 +1.9 163,968 - Ac3H11_4375 0.64 +1.7 163,968 - Ac3H11_4375 0.64 +3.3 163,968 - Ac3H11_4375 0.64 +0.1 163,971 + Ac3H11_4375 0.64 +1.4 163,971 + Ac3H11_4375 0.64 +1.2 163,971 + Ac3H11_4375 0.64 -0.0 163,971 + Ac3H11_4375 0.64 +0.9 163,971 + Ac3H11_4375 0.64 -0.5 163,972 - Ac3H11_4375 0.64 +0.2 163,972 - Ac3H11_4375 0.64 +2.7 163,972 - Ac3H11_4375 0.64 +0.5 163,972 - Ac3H11_4375 0.64 +3.0 163,972 - Ac3H11_4375 0.64 +1.5 163,972 - Ac3H11_4375 0.64 +1.4 163,972 - Ac3H11_4375 0.64 +1.6 164,137 - Ac3H11_4375 0.85 +0.4 164,137 - Ac3H11_4375 0.85 +2.7 164,137 - Ac3H11_4375 0.85 +1.5 164,157 + Ac3H11_4375 0.88 +0.8 164,559 - Ac3H11_4376 0.14 +1.5 164,559 - Ac3H11_4376 0.14 +2.7 164,559 - Ac3H11_4376 0.14 +1.8 164,559 - Ac3H11_4376 0.14 +1.5 164,564 + Ac3H11_4376 0.14 +1.3 164,564 + Ac3H11_4376 0.14 +1.5 164,564 + Ac3H11_4376 0.14 +2.6 164,564 + Ac3H11_4376 0.14 +2.7 164,645 + Ac3H11_4376 0.18 +0.9 164,645 + Ac3H11_4376 0.18 +2.1 164,645 + Ac3H11_4376 0.18 -1.9 164,645 + Ac3H11_4376 0.18 +2.3 164,646 - Ac3H11_4376 0.18 +0.3 164,646 - Ac3H11_4376 0.18 +2.5 164,646 - Ac3H11_4376 0.18 +2.2 164,673 - Ac3H11_4376 0.19 +3.0 164,765 + Ac3H11_4376 0.23 +1.0 164,765 + Ac3H11_4376 0.23 +2.7 164,766 - Ac3H11_4376 0.24 +0.8 164,846 + Ac3H11_4376 0.27 -1.3 164,846 + Ac3H11_4376 0.27 -3.2 164,846 + Ac3H11_4376 0.27 +3.1 164,846 + Ac3H11_4376 0.27 +0.3 164,846 + Ac3H11_4376 0.27 +2.5 164,846 + Ac3H11_4376 0.27 +2.2 164,846 + Ac3H11_4376 0.27 +1.7 164,846 + Ac3H11_4376 0.27 +1.5 164,846 + Ac3H11_4376 0.27 -0.6 164,846 + Ac3H11_4376 0.27 +0.8 164,846 + Ac3H11_4376 0.27 +2.3 164,846 + Ac3H11_4376 0.27 +2.1 164,846 + Ac3H11_4376 0.27 +3.8 164,846 + Ac3H11_4376 0.27 +1.2 164,846 + Ac3H11_4376 0.27 +2.3 164,846 + Ac3H11_4376 0.27 -0.3 164,846 + Ac3H11_4376 0.27 +1.5 164,847 - Ac3H11_4376 0.27 -2.8 164,847 - Ac3H11_4376 0.27 +2.6 164,847 - Ac3H11_4376 0.27 +0.8 164,847 - Ac3H11_4376 0.27 +2.2 164,847 - Ac3H11_4376 0.27 +1.0 164,847 - Ac3H11_4376 0.27 +3.9 164,847 - Ac3H11_4376 0.27 +2.2 164,847 - Ac3H11_4376 0.27 -0.3 164,847 - Ac3H11_4376 0.27 +2.0 164,847 - Ac3H11_4376 0.27 +3.3 164,909 + Ac3H11_4376 0.30 -0.8 164,909 + Ac3H11_4376 0.30 -1.5 164,910 - Ac3H11_4376 0.30 +2.0 164,984 + Ac3H11_4376 0.33 +3.0 164,984 + Ac3H11_4376 0.33 -0.1 164,985 - Ac3H11_4376 0.34 +2.9 164,985 - Ac3H11_4376 0.34 +1.9 164,985 - Ac3H11_4376 0.34 -0.6 165,167 + Ac3H11_4376 0.42 +0.3
Or see this region's nucleotide sequence