Experiment: Cisplatin 0.005 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_1218 and Ac3H11_1219 overlap by 4 nucleotides Ac3H11_1219 and Ac3H11_1220 overlap by 4 nucleotides Ac3H11_1220 and Ac3H11_1221 are separated by 20 nucleotides Ac3H11_1221 and Ac3H11_1222 are separated by 14 nucleotides
Ac3H11_1218 - S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase, at 37,131 to 38,375
_1218
Ac3H11_1219 - FIG026291: Hypothetical periplasmic protein, at 38,372 to 38,968
_1219
Ac3H11_1220 - FIG097052: Sugar transporter, at 38,965 to 40,248
_1220
Ac3H11_1221 - FIG002577: Putative lipoprotein precursor, at 40,269 to 40,808
_1221
Ac3H11_1222 - Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-), at 40,823 to 41,587
_1222
Position (kb)
38
39
40
41 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 37.968 kb on + strand, within Ac3H11_1218 at 37.981 kb on - strand, within Ac3H11_1218 at 37.981 kb on - strand, within Ac3H11_1218 at 38.067 kb on + strand, within Ac3H11_1218 at 38.067 kb on + strand, within Ac3H11_1218 at 38.067 kb on + strand, within Ac3H11_1218 at 38.067 kb on + strand, within Ac3H11_1218 at 38.068 kb on - strand, within Ac3H11_1218 at 38.097 kb on + strand, within Ac3H11_1218 at 38.097 kb on + strand, within Ac3H11_1218 at 38.097 kb on + strand, within Ac3H11_1218 at 38.097 kb on + strand, within Ac3H11_1218 at 38.097 kb on + strand, within Ac3H11_1218 at 38.097 kb on + strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.098 kb on - strand, within Ac3H11_1218 at 38.200 kb on - strand, within Ac3H11_1218 at 38.301 kb on + strand at 38.302 kb on - strand at 38.311 kb on - strand at 38.355 kb on + strand at 38.355 kb on + strand at 38.356 kb on - strand at 38.396 kb on - strand at 38.558 kb on + strand, within Ac3H11_1219 at 38.559 kb on - strand, within Ac3H11_1219 at 38.603 kb on + strand, within Ac3H11_1219 at 38.636 kb on + strand, within Ac3H11_1219 at 38.636 kb on + strand, within Ac3H11_1219 at 38.636 kb on + strand, within Ac3H11_1219 at 38.637 kb on - strand, within Ac3H11_1219 at 38.637 kb on - strand, within Ac3H11_1219 at 38.793 kb on - strand, within Ac3H11_1219 at 39.008 kb on - strand at 39.052 kb on + strand at 39.052 kb on + strand at 39.052 kb on + strand at 39.052 kb on + strand at 39.053 kb on - strand at 39.053 kb on - strand at 39.053 kb on - strand at 39.053 kb on - strand at 39.073 kb on + strand at 39.276 kb on - strand, within Ac3H11_1220 at 39.328 kb on + strand, within Ac3H11_1220 at 39.337 kb on + strand, within Ac3H11_1220 at 39.338 kb on - strand, within Ac3H11_1220 at 39.450 kb on - strand, within Ac3H11_1220 at 39.532 kb on + strand, within Ac3H11_1220 at 39.757 kb on + strand, within Ac3H11_1220 at 39.758 kb on - strand, within Ac3H11_1220 at 39.758 kb on - strand, within Ac3H11_1220 at 40.022 kb on - strand, within Ac3H11_1220 at 40.022 kb on - strand, within Ac3H11_1220 at 40.105 kb on + strand, within Ac3H11_1220 at 40.105 kb on + strand, within Ac3H11_1220 at 40.105 kb on + strand, within Ac3H11_1220 at 40.105 kb on + strand, within Ac3H11_1220 at 40.156 kb on + strand at 40.156 kb on + strand at 40.204 kb on + strand at 40.204 kb on + strand at 40.205 kb on - strand at 40.205 kb on - strand at 40.386 kb on + strand, within Ac3H11_1221 at 40.386 kb on + strand, within Ac3H11_1221 at 40.387 kb on - strand, within Ac3H11_1221 at 40.387 kb on - strand, within Ac3H11_1221 at 40.515 kb on + strand, within Ac3H11_1221 at 40.515 kb on + strand, within Ac3H11_1221 at 40.516 kb on - strand, within Ac3H11_1221 at 40.516 kb on - strand, within Ac3H11_1221 at 40.647 kb on + strand, within Ac3H11_1221 at 40.648 kb on - strand, within Ac3H11_1221 at 40.648 kb on - strand, within Ac3H11_1221 at 40.707 kb on + strand, within Ac3H11_1221 at 40.707 kb on + strand, within Ac3H11_1221 at 40.708 kb on - strand, within Ac3H11_1221 at 40.708 kb on - strand, within Ac3H11_1221 at 40.708 kb on - strand, within Ac3H11_1221 at 40.708 kb on - strand, within Ac3H11_1221 at 40.708 kb on - strand, within Ac3H11_1221 at 41.072 kb on + strand, within Ac3H11_1222 at 41.072 kb on + strand, within Ac3H11_1222 at 41.072 kb on + strand, within Ac3H11_1222 at 41.072 kb on + strand, within Ac3H11_1222 at 41.085 kb on - strand, within Ac3H11_1222 at 41.087 kb on + strand, within Ac3H11_1222 at 41.088 kb on - strand, within Ac3H11_1222 at 41.150 kb on + strand, within Ac3H11_1222 at 41.150 kb on + strand, within Ac3H11_1222
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.005 mg/ml remove 37,968 + Ac3H11_1218 0.67 -0.1 37,981 - Ac3H11_1218 0.68 +0.7 37,981 - Ac3H11_1218 0.68 +0.3 38,067 + Ac3H11_1218 0.75 -2.6 38,067 + Ac3H11_1218 0.75 +1.1 38,067 + Ac3H11_1218 0.75 +2.6 38,067 + Ac3H11_1218 0.75 -3.3 38,068 - Ac3H11_1218 0.75 +0.0 38,097 + Ac3H11_1218 0.78 +0.8 38,097 + Ac3H11_1218 0.78 -0.7 38,097 + Ac3H11_1218 0.78 -1.4 38,097 + Ac3H11_1218 0.78 -1.7 38,097 + Ac3H11_1218 0.78 +0.1 38,097 + Ac3H11_1218 0.78 -3.2 38,098 - Ac3H11_1218 0.78 -2.2 38,098 - Ac3H11_1218 0.78 +0.5 38,098 - Ac3H11_1218 0.78 +1.4 38,098 - Ac3H11_1218 0.78 -3.2 38,098 - Ac3H11_1218 0.78 -0.5 38,098 - Ac3H11_1218 0.78 +0.6 38,098 - Ac3H11_1218 0.78 -1.4 38,098 - Ac3H11_1218 0.78 -1.6 38,098 - Ac3H11_1218 0.78 +1.7 38,200 - Ac3H11_1218 0.86 -1.7 38,301 + -2.4 38,302 - -0.0 38,311 - -1.8 38,355 + +0.8 38,355 + +1.0 38,356 - -0.4 38,396 - +3.2 38,558 + Ac3H11_1219 0.31 +0.6 38,559 - Ac3H11_1219 0.31 +0.3 38,603 + Ac3H11_1219 0.39 +1.0 38,636 + Ac3H11_1219 0.44 +0.8 38,636 + Ac3H11_1219 0.44 +2.1 38,636 + Ac3H11_1219 0.44 +0.7 38,637 - Ac3H11_1219 0.44 +1.8 38,637 - Ac3H11_1219 0.44 +0.9 38,793 - Ac3H11_1219 0.71 +0.2 39,008 - +0.1 39,052 + +0.6 39,052 + +0.8 39,052 + -1.1 39,052 + +1.0 39,053 - +1.3 39,053 - -0.2 39,053 - -1.1 39,053 - -2.9 39,073 + +0.6 39,276 - Ac3H11_1220 0.24 -1.2 39,328 + Ac3H11_1220 0.28 +0.2 39,337 + Ac3H11_1220 0.29 +0.8 39,338 - Ac3H11_1220 0.29 -3.6 39,450 - Ac3H11_1220 0.38 -2.9 39,532 + Ac3H11_1220 0.44 -1.9 39,757 + Ac3H11_1220 0.62 -1.8 39,758 - Ac3H11_1220 0.62 +1.9 39,758 - Ac3H11_1220 0.62 +1.4 40,022 - Ac3H11_1220 0.82 -1.3 40,022 - Ac3H11_1220 0.82 -1.9 40,105 + Ac3H11_1220 0.89 +0.2 40,105 + Ac3H11_1220 0.89 -2.6 40,105 + Ac3H11_1220 0.89 +2.0 40,105 + Ac3H11_1220 0.89 -1.5 40,156 + +1.2 40,156 + +1.4 40,204 + +0.0 40,204 + -1.6 40,205 - -2.1 40,205 - -1.9 40,386 + Ac3H11_1221 0.22 -3.8 40,386 + Ac3H11_1221 0.22 +1.6 40,387 - Ac3H11_1221 0.22 +0.6 40,387 - Ac3H11_1221 0.22 -1.5 40,515 + Ac3H11_1221 0.46 +0.9 40,515 + Ac3H11_1221 0.46 +0.4 40,516 - Ac3H11_1221 0.46 -0.6 40,516 - Ac3H11_1221 0.46 +1.7 40,647 + Ac3H11_1221 0.70 -3.4 40,648 - Ac3H11_1221 0.70 -0.3 40,648 - Ac3H11_1221 0.70 +0.1 40,707 + Ac3H11_1221 0.81 -1.9 40,707 + Ac3H11_1221 0.81 +2.4 40,708 - Ac3H11_1221 0.81 +2.8 40,708 - Ac3H11_1221 0.81 +1.3 40,708 - Ac3H11_1221 0.81 -0.3 40,708 - Ac3H11_1221 0.81 -2.8 40,708 - Ac3H11_1221 0.81 -3.2 41,072 + Ac3H11_1222 0.33 +1.6 41,072 + Ac3H11_1222 0.33 +1.8 41,072 + Ac3H11_1222 0.33 -0.9 41,072 + Ac3H11_1222 0.33 +1.6 41,085 - Ac3H11_1222 0.34 +1.1 41,087 + Ac3H11_1222 0.35 -0.9 41,088 - Ac3H11_1222 0.35 +1.3 41,150 + Ac3H11_1222 0.43 +0.9 41,150 + Ac3H11_1222 0.43 -0.9
Or see this region's nucleotide sequence