Experiment: Cisplatin 0.0025 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_3680 and Ac3H11_3681 are separated by 293 nucleotides Ac3H11_3681 and Ac3H11_3682 are separated by 203 nucleotides Ac3H11_3682 and Ac3H11_3683 are separated by 586 nucleotides
Ac3H11_3680 - putative regulatory prophage protein, at 35,090 to 36,721
_3680
Ac3H11_3681 - hypothetical protein, at 37,015 to 37,164
_3681
Ac3H11_3682 - hypothetical protein, at 37,368 to 37,865
_3682
Ac3H11_3683 - Integrase, at 38,452 to 39,783
_3683
Position (kb) 37
38 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3
4 at 36.393 kb on + strand, within Ac3H11_3680 at 36.393 kb on + strand, within Ac3H11_3680 at 36.393 kb on + strand, within Ac3H11_3680 at 36.393 kb on + strand, within Ac3H11_3680 at 36.393 kb on + strand, within Ac3H11_3680 at 36.394 kb on - strand, within Ac3H11_3680 at 36.394 kb on - strand, within Ac3H11_3680 at 36.573 kb on + strand at 36.573 kb on + strand at 36.574 kb on - strand at 36.574 kb on - strand at 36.617 kb on + strand at 36.617 kb on + strand at 36.618 kb on - strand at 36.618 kb on - strand at 36.701 kb on - strand at 36.755 kb on - strand at 36.755 kb on - strand at 36.814 kb on + strand at 36.814 kb on + strand at 36.814 kb on + strand at 36.814 kb on + strand at 36.814 kb on + strand at 36.815 kb on - strand at 36.815 kb on - strand at 36.815 kb on - strand at 36.901 kb on + strand at 36.901 kb on + strand at 36.902 kb on - strand at 36.902 kb on - strand at 36.905 kb on + strand at 36.905 kb on + strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.906 kb on - strand at 36.942 kb on + strand at 36.942 kb on + strand at 36.942 kb on + strand at 36.943 kb on - strand at 36.943 kb on - strand at 36.943 kb on - strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.956 kb on + strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.957 kb on - strand at 36.960 kb on + strand at 36.960 kb on + strand at 36.960 kb on + strand at 36.960 kb on + strand at 36.960 kb on + strand at 36.960 kb on + strand at 36.960 kb on + strand at 36.961 kb on - strand at 36.961 kb on - strand at 36.961 kb on - strand at 36.961 kb on - strand at 36.961 kb on - strand at 36.986 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.990 kb on + strand at 36.991 kb on - strand at 36.991 kb on - strand at 36.991 kb on - strand at 36.991 kb on - strand at 37.016 kb on + strand at 37.016 kb on + strand at 37.016 kb on + strand at 37.017 kb on - strand at 37.098 kb on + strand, within Ac3H11_3681 at 37.098 kb on + strand, within Ac3H11_3681 at 37.099 kb on - strand, within Ac3H11_3681 at 37.099 kb on - strand, within Ac3H11_3681 at 37.099 kb on - strand, within Ac3H11_3681 at 37.099 kb on - strand, within Ac3H11_3681 at 37.099 kb on - strand, within Ac3H11_3681 at 37.099 kb on - strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.133 kb on + strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.134 kb on - strand, within Ac3H11_3681 at 37.140 kb on + strand, within Ac3H11_3681 at 37.140 kb on + strand, within Ac3H11_3681 at 37.140 kb on + strand, within Ac3H11_3681 at 37.140 kb on + strand, within Ac3H11_3681 at 37.140 kb on + strand, within Ac3H11_3681 at 37.140 kb on + strand, within Ac3H11_3681 at 37.141 kb on - strand, within Ac3H11_3681 at 37.141 kb on - strand, within Ac3H11_3681 at 37.141 kb on - strand, within Ac3H11_3681 at 37.141 kb on - strand, within Ac3H11_3681 at 37.279 kb on + strand at 37.292 kb on - strand at 37.292 kb on - strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.371 kb on + strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.372 kb on - strand at 37.380 kb on + strand at 37.380 kb on + strand at 37.380 kb on + strand at 37.381 kb on - strand at 37.381 kb on - strand at 37.381 kb on - strand at 37.381 kb on - strand at 37.381 kb on - strand at 37.381 kb on - strand at 37.381 kb on - strand at 37.617 kb on + strand, within Ac3H11_3682 at 37.618 kb on - strand, within Ac3H11_3682 at 37.660 kb on - strand, within Ac3H11_3682 at 37.713 kb on + strand, within Ac3H11_3682 at 37.713 kb on + strand, within Ac3H11_3682 at 37.714 kb on - strand, within Ac3H11_3682 at 37.758 kb on + strand, within Ac3H11_3682 at 37.759 kb on - strand, within Ac3H11_3682 at 37.759 kb on - strand, within Ac3H11_3682 at 37.830 kb on + strand at 37.830 kb on + strand at 37.830 kb on + strand at 37.831 kb on - strand at 37.831 kb on - strand at 37.831 kb on - strand at 37.831 kb on - strand at 37.831 kb on - strand at 37.851 kb on + strand at 37.851 kb on + strand at 37.867 kb on + strand at 37.867 kb on + strand at 37.867 kb on + strand at 37.868 kb on - strand at 37.868 kb on - strand at 37.868 kb on - strand at 37.868 kb on - strand at 37.868 kb on - strand at 38.079 kb on + strand at 38.234 kb on + strand at 38.234 kb on + strand at 38.235 kb on - strand at 38.235 kb on - strand at 38.235 kb on - strand at 38.235 kb on - strand at 38.353 kb on + strand at 38.353 kb on + strand at 38.354 kb on - strand at 38.354 kb on - strand at 38.395 kb on - strand at 38.395 kb on - strand at 38.395 kb on - strand at 38.395 kb on - strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.402 kb on + strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.403 kb on - strand at 38.564 kb on - strand at 38.564 kb on - strand at 38.564 kb on - strand at 38.564 kb on - strand at 38.564 kb on - strand at 38.591 kb on - strand, within Ac3H11_3683 at 38.632 kb on + strand, within Ac3H11_3683 at 38.792 kb on - strand, within Ac3H11_3683 at 38.792 kb on - strand, within Ac3H11_3683 at 38.859 kb on + strand, within Ac3H11_3683 at 38.859 kb on + strand, within Ac3H11_3683 at 38.859 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.863 kb on + strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683 at 38.864 kb on - strand, within Ac3H11_3683
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.0025 mg/ml remove 36,393 + Ac3H11_3680 0.80 -0.7 36,393 + Ac3H11_3680 0.80 +1.6 36,393 + Ac3H11_3680 0.80 +3.8 36,393 + Ac3H11_3680 0.80 +1.5 36,393 + Ac3H11_3680 0.80 -2.9 36,394 - Ac3H11_3680 0.80 -1.2 36,394 - Ac3H11_3680 0.80 -1.7 36,573 + -0.5 36,573 + +0.1 36,574 - +0.1 36,574 - -1.9 36,617 + +0.3 36,617 + +1.6 36,618 - +0.2 36,618 - -1.2 36,701 - +0.4 36,755 - +1.3 36,755 - +1.3 36,814 + -0.7 36,814 + -2.3 36,814 + -0.1 36,814 + +1.9 36,814 + -1.2 36,815 - +0.2 36,815 - -0.9 36,815 - -1.2 36,901 + +0.2 36,901 + -0.2 36,902 - -0.9 36,902 - +0.0 36,905 + +0.6 36,905 + -1.4 36,906 - +0.1 36,906 - +0.8 36,906 - +0.6 36,906 - -3.1 36,906 - -1.6 36,906 - +0.3 36,906 - +2.0 36,906 - +3.1 36,906 - -0.0 36,906 - -0.5 36,906 - +0.5 36,942 + +2.9 36,942 + +0.9 36,942 + -2.9 36,943 - -3.2 36,943 - +0.6 36,943 - +1.0 36,956 + -1.9 36,956 + +1.8 36,956 + -1.9 36,956 + -1.2 36,956 + +1.0 36,956 + +0.5 36,956 + -0.3 36,956 + -0.3 36,956 + -0.9 36,956 + +0.0 36,956 + +1.2 36,956 + +0.7 36,957 - +0.4 36,957 - -1.6 36,957 - +0.4 36,957 - -2.6 36,957 - -0.5 36,957 - -0.1 36,957 - -0.4 36,957 - +1.6 36,957 - -0.7 36,957 - +1.0 36,957 - -1.0 36,957 - -1.5 36,957 - -2.3 36,957 - -2.4 36,960 + -0.9 36,960 + +0.5 36,960 + +0.5 36,960 + -0.2 36,960 + -0.6 36,960 + +0.5 36,960 + -0.2 36,961 - -1.1 36,961 - -1.2 36,961 - +0.3 36,961 - +1.5 36,961 - +2.0 36,986 + -2.6 36,990 + -1.0 36,990 + -1.2 36,990 + -1.7 36,990 + +0.8 36,990 + -0.3 36,990 + -2.6 36,990 + +0.5 36,990 + +0.2 36,991 - -3.3 36,991 - -3.1 36,991 - -0.0 36,991 - +1.4 37,016 + -2.2 37,016 + -0.3 37,016 + -3.6 37,017 - -1.0 37,098 + Ac3H11_3681 0.55 -0.9 37,098 + Ac3H11_3681 0.55 -1.2 37,099 - Ac3H11_3681 0.56 -2.3 37,099 - Ac3H11_3681 0.56 +0.1 37,099 - Ac3H11_3681 0.56 +2.0 37,099 - Ac3H11_3681 0.56 -0.1 37,099 - Ac3H11_3681 0.56 +1.3 37,099 - Ac3H11_3681 0.56 -2.3 37,133 + Ac3H11_3681 0.79 -1.4 37,133 + Ac3H11_3681 0.79 +1.1 37,133 + Ac3H11_3681 0.79 +0.1 37,133 + Ac3H11_3681 0.79 +0.6 37,133 + Ac3H11_3681 0.79 +1.5 37,133 + Ac3H11_3681 0.79 -1.6 37,133 + Ac3H11_3681 0.79 -0.5 37,133 + Ac3H11_3681 0.79 -1.4 37,133 + Ac3H11_3681 0.79 -0.5 37,133 + Ac3H11_3681 0.79 +0.7 37,133 + Ac3H11_3681 0.79 +3.3 37,133 + Ac3H11_3681 0.79 -3.8 37,134 - Ac3H11_3681 0.79 -3.6 37,134 - Ac3H11_3681 0.79 -1.6 37,134 - Ac3H11_3681 0.79 -2.2 37,134 - Ac3H11_3681 0.79 -1.7 37,134 - Ac3H11_3681 0.79 -2.4 37,134 - Ac3H11_3681 0.79 -2.2 37,134 - Ac3H11_3681 0.79 +1.6 37,134 - Ac3H11_3681 0.79 -4.4 37,134 - Ac3H11_3681 0.79 +0.2 37,134 - Ac3H11_3681 0.79 +1.0 37,134 - Ac3H11_3681 0.79 -2.0 37,140 + Ac3H11_3681 0.83 -3.6 37,140 + Ac3H11_3681 0.83 +1.5 37,140 + Ac3H11_3681 0.83 -0.7 37,140 + Ac3H11_3681 0.83 -2.1 37,140 + Ac3H11_3681 0.83 +0.9 37,140 + Ac3H11_3681 0.83 -1.0 37,141 - Ac3H11_3681 0.84 +0.8 37,141 - Ac3H11_3681 0.84 +0.9 37,141 - Ac3H11_3681 0.84 -0.4 37,141 - Ac3H11_3681 0.84 -3.0 37,279 + +0.4 37,292 - -3.1 37,292 - +0.3 37,371 + +1.6 37,371 + -0.1 37,371 + +0.6 37,371 + -2.3 37,371 + -3.7 37,371 + +1.0 37,371 + +1.0 37,371 + +1.8 37,372 - +1.5 37,372 - -0.5 37,372 - -2.5 37,372 - +3.1 37,372 - +1.1 37,372 - +0.5 37,372 - +0.8 37,372 - -0.1 37,380 + -0.9 37,380 + -4.1 37,380 + -2.9 37,381 - -1.4 37,381 - -3.7 37,381 - -0.8 37,381 - +0.8 37,381 - -1.1 37,381 - +1.5 37,381 - -2.0 37,617 + Ac3H11_3682 0.50 +0.5 37,618 - Ac3H11_3682 0.50 +0.5 37,660 - Ac3H11_3682 0.59 +0.4 37,713 + Ac3H11_3682 0.69 -1.7 37,713 + Ac3H11_3682 0.69 -1.1 37,714 - Ac3H11_3682 0.69 -2.4 37,758 + Ac3H11_3682 0.78 +2.1 37,759 - Ac3H11_3682 0.79 +1.0 37,759 - Ac3H11_3682 0.79 +2.0 37,830 + +0.7 37,830 + -1.3 37,830 + +0.8 37,831 - -2.3 37,831 - -2.7 37,831 - -1.0 37,831 - +0.6 37,831 - +1.1 37,851 + +1.7 37,851 + +0.4 37,867 + +0.0 37,867 + -0.2 37,867 + -1.3 37,868 - +1.0 37,868 - +0.4 37,868 - +1.0 37,868 - -1.9 37,868 - +2.9 38,079 + +1.0 38,234 + -2.8 38,234 + +1.4 38,235 - +0.8 38,235 - -1.5 38,235 - -2.2 38,235 - -3.0 38,353 + -3.1 38,353 + +0.7 38,354 - +1.2 38,354 - +1.7 38,395 - -1.4 38,395 - -0.2 38,395 - -0.4 38,395 - -0.0 38,402 + -0.4 38,402 + +1.0 38,402 + -1.6 38,402 + +0.4 38,402 + +0.7 38,402 + +2.2 38,402 + -1.7 38,402 + -0.3 38,402 + -1.6 38,402 + +1.0 38,402 + -0.5 38,402 + -1.9 38,403 - +0.6 38,403 - -0.3 38,403 - +1.2 38,403 - +1.1 38,403 - +1.0 38,403 - -0.1 38,403 - -0.7 38,403 - +0.3 38,403 - -1.1 38,403 - -1.1 38,564 - -2.8 38,564 - +0.7 38,564 - +1.7 38,564 - +1.3 38,564 - +0.4 38,591 - Ac3H11_3683 0.10 +0.7 38,632 + Ac3H11_3683 0.14 +1.6 38,792 - Ac3H11_3683 0.26 +1.2 38,792 - Ac3H11_3683 0.26 -1.0 38,859 + Ac3H11_3683 0.31 -0.8 38,859 + Ac3H11_3683 0.31 +1.3 38,859 + Ac3H11_3683 0.31 -1.9 38,863 + Ac3H11_3683 0.31 -1.6 38,863 + Ac3H11_3683 0.31 -1.9 38,863 + Ac3H11_3683 0.31 -3.2 38,863 + Ac3H11_3683 0.31 -3.8 38,863 + Ac3H11_3683 0.31 +0.4 38,863 + Ac3H11_3683 0.31 -1.7 38,863 + Ac3H11_3683 0.31 +1.4 38,863 + Ac3H11_3683 0.31 +0.3 38,863 + Ac3H11_3683 0.31 -2.3 38,864 - Ac3H11_3683 0.31 -0.0 38,864 - Ac3H11_3683 0.31 -1.0 38,864 - Ac3H11_3683 0.31 -0.8 38,864 - Ac3H11_3683 0.31 +0.4 38,864 - Ac3H11_3683 0.31 -2.2 38,864 - Ac3H11_3683 0.31 +0.1 38,864 - Ac3H11_3683 0.31 -2.5 38,864 - Ac3H11_3683 0.31 +1.5 38,864 - Ac3H11_3683 0.31 -2.0
Or see this region's nucleotide sequence