Experiment: Cisplatin 0.0025 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_3636 and Ac3H11_3637 overlap by 4 nucleotides Ac3H11_3637 and Ac3H11_3638 are separated by 163 nucleotides
Ac3H11_3636 - hypothetical protein, at 194,383 to 195,855
_3636
Ac3H11_3637 - C-1'-hydroxylase CruF, at 195,852 to 196,673
_3637
Ac3H11_3638 - Biotin synthesis protein BioH, at 196,837 to 197,658
_3638
Position (kb)
195
196
197 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 195.008 kb on + strand, within Ac3H11_3636 at 195.008 kb on + strand, within Ac3H11_3636 at 195.008 kb on + strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.009 kb on - strand, within Ac3H11_3636 at 195.081 kb on + strand, within Ac3H11_3636 at 195.082 kb on - strand, within Ac3H11_3636 at 195.093 kb on - strand, within Ac3H11_3636 at 195.093 kb on - strand, within Ac3H11_3636 at 195.152 kb on + strand, within Ac3H11_3636 at 195.152 kb on + strand, within Ac3H11_3636 at 195.153 kb on - strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.458 kb on + strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.459 kb on - strand, within Ac3H11_3636 at 195.587 kb on + strand, within Ac3H11_3636 at 195.587 kb on + strand, within Ac3H11_3636 at 195.587 kb on + strand, within Ac3H11_3636 at 195.588 kb on - strand, within Ac3H11_3636 at 195.588 kb on - strand, within Ac3H11_3636 at 195.588 kb on - strand, within Ac3H11_3636 at 195.588 kb on - strand, within Ac3H11_3636 at 195.588 kb on - strand, within Ac3H11_3636 at 195.855 kb on + strand at 195.889 kb on + strand at 195.994 kb on + strand, within Ac3H11_3637 at 195.994 kb on + strand, within Ac3H11_3637 at 195.994 kb on + strand, within Ac3H11_3637 at 195.994 kb on + strand, within Ac3H11_3637 at 195.995 kb on - strand, within Ac3H11_3637 at 195.995 kb on - strand, within Ac3H11_3637 at 195.995 kb on - strand, within Ac3H11_3637 at 196.183 kb on + strand, within Ac3H11_3637 at 196.183 kb on + strand, within Ac3H11_3637 at 196.183 kb on + strand, within Ac3H11_3637 at 196.184 kb on - strand, within Ac3H11_3637 at 196.192 kb on + strand, within Ac3H11_3637 at 196.192 kb on + strand, within Ac3H11_3637 at 196.192 kb on + strand, within Ac3H11_3637 at 196.192 kb on + strand, within Ac3H11_3637 at 196.193 kb on - strand, within Ac3H11_3637 at 196.193 kb on - strand, within Ac3H11_3637 at 196.318 kb on + strand, within Ac3H11_3637 at 196.318 kb on + strand, within Ac3H11_3637 at 196.319 kb on - strand, within Ac3H11_3637 at 196.327 kb on + strand, within Ac3H11_3637 at 196.327 kb on + strand, within Ac3H11_3637 at 196.327 kb on + strand, within Ac3H11_3637 at 196.327 kb on + strand, within Ac3H11_3637 at 196.328 kb on - strand, within Ac3H11_3637 at 196.328 kb on - strand, within Ac3H11_3637 at 196.328 kb on - strand, within Ac3H11_3637 at 196.328 kb on - strand, within Ac3H11_3637 at 196.328 kb on - strand, within Ac3H11_3637 at 196.399 kb on + strand, within Ac3H11_3637 at 196.399 kb on + strand, within Ac3H11_3637 at 196.400 kb on - strand, within Ac3H11_3637 at 196.400 kb on - strand, within Ac3H11_3637 at 196.400 kb on - strand, within Ac3H11_3637 at 196.400 kb on - strand, within Ac3H11_3637 at 196.400 kb on - strand, within Ac3H11_3637 at 196.405 kb on + strand, within Ac3H11_3637 at 196.405 kb on + strand, within Ac3H11_3637 at 196.405 kb on + strand, within Ac3H11_3637 at 196.405 kb on + strand, within Ac3H11_3637 at 196.405 kb on + strand, within Ac3H11_3637 at 196.406 kb on - strand, within Ac3H11_3637 at 196.406 kb on - strand, within Ac3H11_3637 at 196.406 kb on - strand, within Ac3H11_3637 at 196.406 kb on - strand, within Ac3H11_3637 at 196.406 kb on - strand, within Ac3H11_3637 at 196.610 kb on - strand at 196.610 kb on - strand at 196.610 kb on - strand at 196.627 kb on + strand at 196.627 kb on + strand at 196.628 kb on - strand at 196.628 kb on - strand at 196.628 kb on - strand at 196.693 kb on - strand at 196.709 kb on + strand at 196.710 kb on - strand at 196.710 kb on - strand at 196.710 kb on - strand at 196.805 kb on - strand at 196.805 kb on - strand at 196.806 kb on + strand at 196.806 kb on + strand at 196.806 kb on + strand at 196.806 kb on + strand at 196.806 kb on + strand at 196.807 kb on - strand at 196.807 kb on - strand at 196.807 kb on - strand at 196.807 kb on - strand at 196.807 kb on - strand at 196.807 kb on - strand at 197.090 kb on + strand, within Ac3H11_3638 at 197.090 kb on + strand, within Ac3H11_3638 at 197.090 kb on + strand, within Ac3H11_3638 at 197.090 kb on + strand, within Ac3H11_3638 at 197.090 kb on + strand, within Ac3H11_3638 at 197.091 kb on - strand, within Ac3H11_3638 at 197.091 kb on - strand, within Ac3H11_3638 at 197.091 kb on - strand, within Ac3H11_3638 at 197.091 kb on - strand, within Ac3H11_3638 at 197.091 kb on - strand, within Ac3H11_3638 at 197.165 kb on + strand, within Ac3H11_3638 at 197.165 kb on + strand, within Ac3H11_3638 at 197.165 kb on + strand, within Ac3H11_3638 at 197.165 kb on + strand, within Ac3H11_3638 at 197.165 kb on + strand, within Ac3H11_3638 at 197.165 kb on + strand, within Ac3H11_3638 at 197.166 kb on - strand, within Ac3H11_3638 at 197.166 kb on - strand, within Ac3H11_3638 at 197.166 kb on - strand, within Ac3H11_3638 at 197.609 kb on + strand at 197.609 kb on + strand at 197.609 kb on + strand at 197.610 kb on - strand at 197.610 kb on - strand at 197.614 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.0025 mg/ml remove 195,008 + Ac3H11_3636 0.42 +0.8 195,008 + Ac3H11_3636 0.42 +1.3 195,008 + Ac3H11_3636 0.42 +1.4 195,009 - Ac3H11_3636 0.42 -0.4 195,009 - Ac3H11_3636 0.42 -1.5 195,009 - Ac3H11_3636 0.42 -2.0 195,009 - Ac3H11_3636 0.42 -1.4 195,009 - Ac3H11_3636 0.42 -1.5 195,009 - Ac3H11_3636 0.42 +0.1 195,009 - Ac3H11_3636 0.42 -1.1 195,081 + Ac3H11_3636 0.47 -2.6 195,082 - Ac3H11_3636 0.47 +1.0 195,093 - Ac3H11_3636 0.48 -0.1 195,093 - Ac3H11_3636 0.48 -1.6 195,152 + Ac3H11_3636 0.52 +1.0 195,152 + Ac3H11_3636 0.52 +1.2 195,153 - Ac3H11_3636 0.52 -1.5 195,458 + Ac3H11_3636 0.73 +1.3 195,458 + Ac3H11_3636 0.73 +0.8 195,458 + Ac3H11_3636 0.73 -1.3 195,458 + Ac3H11_3636 0.73 +1.3 195,458 + Ac3H11_3636 0.73 -0.7 195,458 + Ac3H11_3636 0.73 -0.1 195,458 + Ac3H11_3636 0.73 +1.1 195,459 - Ac3H11_3636 0.73 +0.4 195,459 - Ac3H11_3636 0.73 -1.0 195,459 - Ac3H11_3636 0.73 -0.3 195,459 - Ac3H11_3636 0.73 -1.4 195,459 - Ac3H11_3636 0.73 +0.3 195,459 - Ac3H11_3636 0.73 -0.9 195,459 - Ac3H11_3636 0.73 +2.6 195,459 - Ac3H11_3636 0.73 +0.7 195,587 + Ac3H11_3636 0.82 +2.1 195,587 + Ac3H11_3636 0.82 -0.4 195,587 + Ac3H11_3636 0.82 -0.5 195,588 - Ac3H11_3636 0.82 +0.6 195,588 - Ac3H11_3636 0.82 +1.8 195,588 - Ac3H11_3636 0.82 -0.5 195,588 - Ac3H11_3636 0.82 -0.7 195,588 - Ac3H11_3636 0.82 -1.8 195,855 + -1.3 195,889 + -0.7 195,994 + Ac3H11_3637 0.17 -0.6 195,994 + Ac3H11_3637 0.17 +1.0 195,994 + Ac3H11_3637 0.17 -1.8 195,994 + Ac3H11_3637 0.17 -0.3 195,995 - Ac3H11_3637 0.17 +0.8 195,995 - Ac3H11_3637 0.17 +2.5 195,995 - Ac3H11_3637 0.17 +2.1 196,183 + Ac3H11_3637 0.40 -0.4 196,183 + Ac3H11_3637 0.40 -1.3 196,183 + Ac3H11_3637 0.40 -3.0 196,184 - Ac3H11_3637 0.40 -1.5 196,192 + Ac3H11_3637 0.41 +0.1 196,192 + Ac3H11_3637 0.41 +0.7 196,192 + Ac3H11_3637 0.41 -2.3 196,192 + Ac3H11_3637 0.41 -1.0 196,193 - Ac3H11_3637 0.41 +1.0 196,193 - Ac3H11_3637 0.41 +0.6 196,318 + Ac3H11_3637 0.57 -0.9 196,318 + Ac3H11_3637 0.57 +0.7 196,319 - Ac3H11_3637 0.57 -1.5 196,327 + Ac3H11_3637 0.58 +1.2 196,327 + Ac3H11_3637 0.58 -2.6 196,327 + Ac3H11_3637 0.58 +1.1 196,327 + Ac3H11_3637 0.58 +1.1 196,328 - Ac3H11_3637 0.58 +2.0 196,328 - Ac3H11_3637 0.58 +1.6 196,328 - Ac3H11_3637 0.58 +0.3 196,328 - Ac3H11_3637 0.58 -2.7 196,328 - Ac3H11_3637 0.58 +0.6 196,399 + Ac3H11_3637 0.67 +1.2 196,399 + Ac3H11_3637 0.67 -3.8 196,400 - Ac3H11_3637 0.67 -0.9 196,400 - Ac3H11_3637 0.67 -0.9 196,400 - Ac3H11_3637 0.67 -0.6 196,400 - Ac3H11_3637 0.67 -1.0 196,400 - Ac3H11_3637 0.67 +0.6 196,405 + Ac3H11_3637 0.67 +2.0 196,405 + Ac3H11_3637 0.67 +0.8 196,405 + Ac3H11_3637 0.67 -0.5 196,405 + Ac3H11_3637 0.67 -2.4 196,405 + Ac3H11_3637 0.67 +1.0 196,406 - Ac3H11_3637 0.67 -1.3 196,406 - Ac3H11_3637 0.67 -0.4 196,406 - Ac3H11_3637 0.67 -0.5 196,406 - Ac3H11_3637 0.67 -1.1 196,406 - Ac3H11_3637 0.67 +1.8 196,610 - -0.0 196,610 - +0.2 196,610 - -3.0 196,627 + -1.5 196,627 + +0.5 196,628 - -0.5 196,628 - -0.0 196,628 - -0.3 196,693 - -0.6 196,709 + +1.2 196,710 - +1.1 196,710 - -0.1 196,710 - +0.4 196,805 - -0.9 196,805 - +1.6 196,806 + +0.9 196,806 + +1.4 196,806 + -3.5 196,806 + -0.4 196,806 + +0.6 196,807 - +0.1 196,807 - -0.6 196,807 - -0.5 196,807 - -0.1 196,807 - -1.2 196,807 - -0.9 197,090 + Ac3H11_3638 0.31 -0.4 197,090 + Ac3H11_3638 0.31 -0.1 197,090 + Ac3H11_3638 0.31 +1.1 197,090 + Ac3H11_3638 0.31 +1.8 197,090 + Ac3H11_3638 0.31 +0.5 197,091 - Ac3H11_3638 0.31 +1.6 197,091 - Ac3H11_3638 0.31 +1.3 197,091 - Ac3H11_3638 0.31 +0.1 197,091 - Ac3H11_3638 0.31 +0.6 197,091 - Ac3H11_3638 0.31 +2.1 197,165 + Ac3H11_3638 0.40 +2.6 197,165 + Ac3H11_3638 0.40 +0.4 197,165 + Ac3H11_3638 0.40 -0.2 197,165 + Ac3H11_3638 0.40 +1.6 197,165 + Ac3H11_3638 0.40 -2.1 197,165 + Ac3H11_3638 0.40 -2.3 197,166 - Ac3H11_3638 0.40 +1.1 197,166 - Ac3H11_3638 0.40 +0.2 197,166 - Ac3H11_3638 0.40 +0.5 197,609 + +1.3 197,609 + +0.6 197,609 + +0.1 197,610 - -1.0 197,610 - -2.6 197,614 - +2.4
Or see this region's nucleotide sequence