Experiment: L-Histidine (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf6N2E2_3804 and Pf6N2E2_3805 are separated by 152 nucleotides Pf6N2E2_3805 and Pf6N2E2_3806 are separated by 925 nucleotides
Pf6N2E2_3804 - Cytosine/purine/uracil/thiamine/allantoin permease family protein, at 4,431,750 to 4,433,216
_3804
Pf6N2E2_3805 - Urocanate hydratase (EC 4.2.1.49) (from data) , at 4,433,369 to 4,435,057
_3805
Pf6N2E2_3806 - Conserved hypothetical protein (perhaps related to histidine degradation), at 4,435,983 to 4,436,552
_3806
Position (kb)
4433
4434
4435
4436 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1 at 4432.393 kb on + strand, within Pf6N2E2_3804 at 4432.393 kb on + strand, within Pf6N2E2_3804 at 4432.393 kb on + strand, within Pf6N2E2_3804 at 4432.543 kb on + strand, within Pf6N2E2_3804 at 4432.543 kb on + strand, within Pf6N2E2_3804 at 4432.682 kb on - strand, within Pf6N2E2_3804 at 4432.682 kb on - strand, within Pf6N2E2_3804 at 4432.867 kb on + strand, within Pf6N2E2_3804 at 4432.867 kb on + strand, within Pf6N2E2_3804 at 4432.867 kb on + strand, within Pf6N2E2_3804 at 4432.868 kb on - strand, within Pf6N2E2_3804 at 4432.906 kb on + strand, within Pf6N2E2_3804 at 4432.906 kb on + strand, within Pf6N2E2_3804 at 4432.906 kb on + strand, within Pf6N2E2_3804 at 4432.907 kb on - strand, within Pf6N2E2_3804 at 4433.156 kb on - strand at 4433.156 kb on - strand at 4433.204 kb on + strand at 4433.371 kb on - strand at 4433.483 kb on + strand at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.925 kb on + strand, within Pf6N2E2_3805 at 4433.926 kb on - strand, within Pf6N2E2_3805 at 4433.926 kb on - strand, within Pf6N2E2_3805 at 4433.926 kb on - strand, within Pf6N2E2_3805 at 4433.926 kb on - strand, within Pf6N2E2_3805 at 4433.926 kb on - strand, within Pf6N2E2_3805 at 4433.926 kb on - strand, within Pf6N2E2_3805 at 4434.000 kb on + strand, within Pf6N2E2_3805 at 4434.000 kb on + strand, within Pf6N2E2_3805 at 4434.000 kb on + strand, within Pf6N2E2_3805 at 4434.001 kb on - strand, within Pf6N2E2_3805 at 4434.001 kb on - strand, within Pf6N2E2_3805 at 4434.001 kb on - strand, within Pf6N2E2_3805 at 4434.001 kb on - strand, within Pf6N2E2_3805 at 4434.079 kb on - strand, within Pf6N2E2_3805 at 4434.225 kb on + strand, within Pf6N2E2_3805 at 4434.360 kb on + strand, within Pf6N2E2_3805 at 4434.361 kb on - strand, within Pf6N2E2_3805 at 4434.361 kb on - strand, within Pf6N2E2_3805 at 4434.565 kb on - strand, within Pf6N2E2_3805 at 4434.597 kb on + strand, within Pf6N2E2_3805 at 4434.598 kb on - strand, within Pf6N2E2_3805 at 4434.601 kb on + strand, within Pf6N2E2_3805 at 4434.631 kb on - strand, within Pf6N2E2_3805 at 4434.660 kb on + strand, within Pf6N2E2_3805 at 4434.660 kb on + strand, within Pf6N2E2_3805 at 4434.660 kb on + strand, within Pf6N2E2_3805 at 4434.660 kb on + strand, within Pf6N2E2_3805 at 4434.661 kb on - strand, within Pf6N2E2_3805 at 4434.661 kb on - strand, within Pf6N2E2_3805 at 4434.852 kb on + strand, within Pf6N2E2_3805 at 4434.852 kb on + strand, within Pf6N2E2_3805 at 4434.881 kb on + strand, within Pf6N2E2_3805 at 4434.881 kb on + strand, within Pf6N2E2_3805 at 4434.881 kb on + strand, within Pf6N2E2_3805 at 4434.882 kb on - strand, within Pf6N2E2_3805 at 4434.882 kb on - strand, within Pf6N2E2_3805 at 4434.882 kb on - strand, within Pf6N2E2_3805 at 4434.882 kb on - strand, within Pf6N2E2_3805 at 4434.891 kb on + strand at 4434.892 kb on - strand at 4435.132 kb on - strand at 4435.144 kb on + strand at 4435.144 kb on + strand at 4435.144 kb on + strand at 4435.144 kb on + strand at 4435.144 kb on + strand at 4435.145 kb on - strand at 4435.150 kb on + strand at 4435.151 kb on - strand at 4435.151 kb on - strand at 4435.151 kb on - strand at 4435.159 kb on - strand at 4435.164 kb on + strand at 4435.176 kb on + strand at 4435.587 kb on - strand at 4435.587 kb on - strand at 4435.902 kb on + strand at 4435.902 kb on + strand at 4435.902 kb on + strand at 4435.902 kb on + strand at 4435.902 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction L-Histidine (C) remove 4,432,393 + Pf6N2E2_3804 0.44 -3.0 4,432,393 + Pf6N2E2_3804 0.44 -2.2 4,432,393 + Pf6N2E2_3804 0.44 -3.6 4,432,543 + Pf6N2E2_3804 0.54 -3.6 4,432,543 + Pf6N2E2_3804 0.54 -5.4 4,432,682 - Pf6N2E2_3804 0.64 -3.2 4,432,682 - Pf6N2E2_3804 0.64 -4.2 4,432,867 + Pf6N2E2_3804 0.76 -2.7 4,432,867 + Pf6N2E2_3804 0.76 -2.2 4,432,867 + Pf6N2E2_3804 0.76 -4.0 4,432,868 - Pf6N2E2_3804 0.76 -3.5 4,432,906 + Pf6N2E2_3804 0.79 -0.5 4,432,906 + Pf6N2E2_3804 0.79 -3.5 4,432,906 + Pf6N2E2_3804 0.79 -3.9 4,432,907 - Pf6N2E2_3804 0.79 -2.5 4,433,156 - -4.4 4,433,156 - -1.3 4,433,204 + -3.5 4,433,371 - -2.3 4,433,483 + -1.7 4,433,925 + Pf6N2E2_3805 0.33 -1.1 4,433,925 + Pf6N2E2_3805 0.33 -2.5 4,433,925 + Pf6N2E2_3805 0.33 -1.9 4,433,925 + Pf6N2E2_3805 0.33 -2.8 4,433,925 + Pf6N2E2_3805 0.33 -3.9 4,433,925 + Pf6N2E2_3805 0.33 -2.5 4,433,925 + Pf6N2E2_3805 0.33 -4.6 4,433,925 + Pf6N2E2_3805 0.33 -2.8 4,433,925 + Pf6N2E2_3805 0.33 -3.5 4,433,926 - Pf6N2E2_3805 0.33 -3.8 4,433,926 - Pf6N2E2_3805 0.33 -2.3 4,433,926 - Pf6N2E2_3805 0.33 -3.9 4,433,926 - Pf6N2E2_3805 0.33 -3.1 4,433,926 - Pf6N2E2_3805 0.33 -3.4 4,433,926 - Pf6N2E2_3805 0.33 -2.4 4,434,000 + Pf6N2E2_3805 0.37 -4.3 4,434,000 + Pf6N2E2_3805 0.37 -3.4 4,434,000 + Pf6N2E2_3805 0.37 -2.7 4,434,001 - Pf6N2E2_3805 0.37 -3.9 4,434,001 - Pf6N2E2_3805 0.37 -0.8 4,434,001 - Pf6N2E2_3805 0.37 -1.7 4,434,001 - Pf6N2E2_3805 0.37 -1.8 4,434,079 - Pf6N2E2_3805 0.42 -1.7 4,434,225 + Pf6N2E2_3805 0.51 -5.1 4,434,360 + Pf6N2E2_3805 0.59 -2.5 4,434,361 - Pf6N2E2_3805 0.59 -3.9 4,434,361 - Pf6N2E2_3805 0.59 -4.1 4,434,565 - Pf6N2E2_3805 0.71 -3.1 4,434,597 + Pf6N2E2_3805 0.73 -2.4 4,434,598 - Pf6N2E2_3805 0.73 -4.8 4,434,601 + Pf6N2E2_3805 0.73 -3.3 4,434,631 - Pf6N2E2_3805 0.75 -2.6 4,434,660 + Pf6N2E2_3805 0.76 -0.4 4,434,660 + Pf6N2E2_3805 0.76 -3.9 4,434,660 + Pf6N2E2_3805 0.76 -2.0 4,434,660 + Pf6N2E2_3805 0.76 -3.3 4,434,661 - Pf6N2E2_3805 0.76 -4.5 4,434,661 - Pf6N2E2_3805 0.76 -3.8 4,434,852 + Pf6N2E2_3805 0.88 -4.6 4,434,852 + Pf6N2E2_3805 0.88 -3.9 4,434,881 + Pf6N2E2_3805 0.90 -4.3 4,434,881 + Pf6N2E2_3805 0.90 -3.1 4,434,881 + Pf6N2E2_3805 0.90 +0.5 4,434,882 - Pf6N2E2_3805 0.90 -1.1 4,434,882 - Pf6N2E2_3805 0.90 -3.3 4,434,882 - Pf6N2E2_3805 0.90 -3.3 4,434,882 - Pf6N2E2_3805 0.90 -4.3 4,434,891 + -3.9 4,434,892 - -2.7 4,435,132 - -3.9 4,435,144 + -4.4 4,435,144 + -3.1 4,435,144 + -2.6 4,435,144 + -3.6 4,435,144 + -4.0 4,435,145 - -2.9 4,435,150 + -1.9 4,435,151 - -2.5 4,435,151 - -2.0 4,435,151 - -1.5 4,435,159 - -3.6 4,435,164 + -4.5 4,435,176 + -1.5 4,435,587 - -0.8 4,435,587 - -0.8 4,435,902 + -0.2 4,435,902 + -0.7 4,435,902 + -0.3 4,435,902 + -0.7 4,435,902 + -2.1
Or see this region's nucleotide sequence