Experiment: Cisplatin 0.006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt AO353_01345 and AO353_01350 are separated by 3 nucleotides AO353_01350 and AO353_01355 overlap by 1 nucleotides AO353_01355 and AO353_01360 are separated by 110 nucleotides AO353_01360 and AO353_01365 are separated by 197 nucleotides
AO353_01345: AO353_01345 - aminodeoxychorismate lyase, at 290,226 to 291,416
_01345
AO353_01350: AO353_01350 - 4-amino-4-deoxychorismate lyase, at 291,420 to 292,235
_01350
AO353_01355: AO353_01355 - 3-oxoacyl-ACP synthase, at 292,235 to 293,479
_01355
AO353_01360: AO353_01360 - acyl carrier protein, at 293,590 to 293,826
_01360
AO353_01365: AO353_01365 - 3-ketoacyl-ACP reductase, at 294,024 to 294,764
_01365
Position (kb) 292
293
294 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3
4
5 at 291.283 kb on - strand, within AO353_01345 at 291.283 kb on - strand, within AO353_01345 at 291.292 kb on - strand, within AO353_01345 at 291.292 kb on - strand, within AO353_01345 at 291.292 kb on - strand, within AO353_01345 at 291.292 kb on - strand, within AO353_01345 at 291.306 kb on - strand at 291.364 kb on - strand at 291.408 kb on - strand at 291.408 kb on - strand at 291.408 kb on - strand at 291.408 kb on - strand at 291.496 kb on + strand at 291.496 kb on + strand at 291.496 kb on + strand at 291.496 kb on + strand at 291.496 kb on + strand at 291.497 kb on - strand at 291.497 kb on - strand at 291.497 kb on - strand at 291.497 kb on - strand at 291.497 kb on - strand at 291.497 kb on - strand at 291.497 kb on - strand at 291.520 kb on + strand, within AO353_01350 at 291.520 kb on + strand, within AO353_01350 at 291.704 kb on + strand, within AO353_01350 at 291.704 kb on + strand, within AO353_01350 at 291.875 kb on + strand, within AO353_01350 at 291.875 kb on + strand, within AO353_01350 at 291.875 kb on + strand, within AO353_01350 at 291.876 kb on - strand, within AO353_01350 at 291.876 kb on - strand, within AO353_01350 at 291.921 kb on + strand, within AO353_01350 at 291.921 kb on + strand, within AO353_01350 at 291.922 kb on - strand, within AO353_01350 at 291.922 kb on - strand, within AO353_01350 at 291.922 kb on - strand, within AO353_01350 at 291.929 kb on + strand, within AO353_01350 at 291.929 kb on + strand, within AO353_01350 at 291.929 kb on + strand, within AO353_01350 at 291.929 kb on + strand, within AO353_01350 at 291.929 kb on + strand, within AO353_01350 at 291.930 kb on - strand, within AO353_01350 at 292.027 kb on + strand, within AO353_01350 at 292.027 kb on + strand, within AO353_01350 at 292.027 kb on + strand, within AO353_01350 at 292.028 kb on - strand, within AO353_01350 at 292.028 kb on - strand, within AO353_01350 at 292.319 kb on - strand at 292.319 kb on - strand at 292.319 kb on - strand at 292.564 kb on + strand, within AO353_01355 at 292.564 kb on + strand, within AO353_01355 at 292.564 kb on + strand, within AO353_01355 at 292.565 kb on - strand, within AO353_01355 at 292.565 kb on - strand, within AO353_01355 at 292.565 kb on - strand, within AO353_01355 at 292.581 kb on + strand, within AO353_01355 at 292.581 kb on + strand, within AO353_01355 at 292.581 kb on + strand, within AO353_01355 at 292.581 kb on + strand, within AO353_01355 at 292.582 kb on - strand, within AO353_01355 at 292.582 kb on - strand, within AO353_01355 at 292.582 kb on - strand, within AO353_01355 at 292.582 kb on - strand, within AO353_01355 at 292.582 kb on - strand, within AO353_01355 at 292.716 kb on + strand, within AO353_01355 at 292.717 kb on - strand, within AO353_01355 at 292.969 kb on + strand, within AO353_01355 at 292.988 kb on - strand, within AO353_01355 at 293.007 kb on + strand, within AO353_01355 at 293.007 kb on + strand, within AO353_01355 at 293.007 kb on + strand, within AO353_01355 at 293.008 kb on - strand, within AO353_01355 at 293.008 kb on - strand, within AO353_01355 at 293.008 kb on - strand, within AO353_01355 at 293.008 kb on - strand, within AO353_01355 at 293.008 kb on - strand, within AO353_01355 at 293.011 kb on + strand, within AO353_01355 at 293.023 kb on + strand, within AO353_01355 at 293.056 kb on + strand, within AO353_01355 at 293.057 kb on - strand, within AO353_01355 at 293.057 kb on - strand, within AO353_01355 at 293.057 kb on - strand, within AO353_01355 at 293.180 kb on - strand, within AO353_01355 at 293.180 kb on - strand, within AO353_01355 at 293.250 kb on + strand, within AO353_01355 at 293.251 kb on - strand, within AO353_01355 at 293.295 kb on + strand, within AO353_01355 at 293.295 kb on + strand, within AO353_01355 at 293.295 kb on + strand, within AO353_01355 at 293.296 kb on - strand, within AO353_01355 at 293.343 kb on + strand, within AO353_01355 at 293.343 kb on + strand, within AO353_01355 at 293.344 kb on - strand, within AO353_01355 at 293.398 kb on + strand at 293.398 kb on + strand at 293.399 kb on - strand at 293.443 kb on + strand at 293.443 kb on + strand at 293.443 kb on + strand at 293.443 kb on + strand at 293.443 kb on + strand at 293.443 kb on + strand at 293.444 kb on - strand at 293.444 kb on - strand at 293.444 kb on - strand at 293.520 kb on + strand at 293.521 kb on - strand at 293.521 kb on - strand at 293.876 kb on - strand at 293.884 kb on - strand at 293.947 kb on - strand at 293.949 kb on - strand at 293.949 kb on - strand at 293.949 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.953 kb on - strand at 293.966 kb on - strand at 293.966 kb on - strand at 293.966 kb on - strand at 293.966 kb on - strand at 293.968 kb on - strand at 293.989 kb on - strand at 293.989 kb on - strand at 293.989 kb on - strand at 294.026 kb on - strand at 294.026 kb on - strand at 294.026 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand at 294.032 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.006 mg/ml remove 291,283 - AO353_01345 0.89 +1.7 291,283 - AO353_01345 0.89 -0.2 291,292 - AO353_01345 0.90 +1.9 291,292 - AO353_01345 0.90 +0.3 291,292 - AO353_01345 0.90 +1.7 291,292 - AO353_01345 0.90 +1.8 291,306 - -1.7 291,364 - -0.2 291,408 - +2.3 291,408 - +1.1 291,408 - +2.2 291,408 - -1.2 291,496 + -1.7 291,496 + -0.2 291,496 + +1.4 291,496 + -0.2 291,496 + +1.4 291,497 - +1.4 291,497 - -1.3 291,497 - -2.2 291,497 - -0.2 291,497 - +0.4 291,497 - -1.2 291,497 - -2.2 291,520 + AO353_01350 0.12 -0.2 291,520 + AO353_01350 0.12 -1.7 291,704 + AO353_01350 0.35 -1.5 291,704 + AO353_01350 0.35 -1.7 291,875 + AO353_01350 0.56 -1.7 291,875 + AO353_01350 0.56 -2.5 291,875 + AO353_01350 0.56 +0.3 291,876 - AO353_01350 0.56 -1.7 291,876 - AO353_01350 0.56 -1.2 291,921 + AO353_01350 0.61 -0.7 291,921 + AO353_01350 0.61 -1.2 291,922 - AO353_01350 0.62 -2.2 291,922 - AO353_01350 0.62 -0.3 291,922 - AO353_01350 0.62 +5.2 291,929 + AO353_01350 0.62 -1.7 291,929 + AO353_01350 0.62 -0.2 291,929 + AO353_01350 0.62 -0.2 291,929 + AO353_01350 0.62 -1.2 291,929 + AO353_01350 0.62 -2.5 291,930 - AO353_01350 0.62 -1.2 292,027 + AO353_01350 0.74 -0.7 292,027 + AO353_01350 0.74 -1.7 292,027 + AO353_01350 0.74 -1.7 292,028 - AO353_01350 0.75 +1.0 292,028 - AO353_01350 0.75 -2.5 292,319 - -2.2 292,319 - +0.8 292,319 - -0.2 292,564 + AO353_01355 0.26 -0.2 292,564 + AO353_01355 0.26 -1.7 292,564 + AO353_01355 0.26 -1.7 292,565 - AO353_01355 0.27 -2.7 292,565 - AO353_01355 0.27 -0.2 292,565 - AO353_01355 0.27 -2.2 292,581 + AO353_01355 0.28 -1.2 292,581 + AO353_01355 0.28 -2.5 292,581 + AO353_01355 0.28 -0.2 292,581 + AO353_01355 0.28 -1.7 292,582 - AO353_01355 0.28 -0.2 292,582 - AO353_01355 0.28 -1.7 292,582 - AO353_01355 0.28 -1.2 292,582 - AO353_01355 0.28 +3.3 292,582 - AO353_01355 0.28 -0.2 292,716 + AO353_01355 0.39 -1.7 292,717 - AO353_01355 0.39 -1.2 292,969 + AO353_01355 0.59 -2.7 292,988 - AO353_01355 0.60 -1.2 293,007 + AO353_01355 0.62 +0.8 293,007 + AO353_01355 0.62 -1.7 293,007 + AO353_01355 0.62 -0.2 293,008 - AO353_01355 0.62 -0.7 293,008 - AO353_01355 0.62 -0.9 293,008 - AO353_01355 0.62 -0.2 293,008 - AO353_01355 0.62 -1.2 293,008 - AO353_01355 0.62 -0.2 293,011 + AO353_01355 0.62 -1.7 293,023 + AO353_01355 0.63 -1.7 293,056 + AO353_01355 0.66 -0.2 293,057 - AO353_01355 0.66 -2.5 293,057 - AO353_01355 0.66 -3.5 293,057 - AO353_01355 0.66 -2.2 293,180 - AO353_01355 0.76 -1.2 293,180 - AO353_01355 0.76 -0.2 293,250 + AO353_01355 0.82 -2.7 293,251 - AO353_01355 0.82 -2.7 293,295 + AO353_01355 0.85 -0.2 293,295 + AO353_01355 0.85 -1.2 293,295 + AO353_01355 0.85 -2.7 293,296 - AO353_01355 0.85 -3.0 293,343 + AO353_01355 0.89 -1.2 293,343 + AO353_01355 0.89 -0.2 293,344 - AO353_01355 0.89 -0.2 293,398 + -1.2 293,398 + -0.2 293,399 - -1.2 293,443 + +0.8 293,443 + +0.4 293,443 + -2.2 293,443 + -1.2 293,443 + -1.2 293,443 + -1.2 293,444 - -2.5 293,444 - -2.2 293,444 - -1.2 293,520 + -2.7 293,521 - -3.9 293,521 - -2.5 293,876 - -1.2 293,884 - -2.2 293,947 - -2.2 293,949 - -3.2 293,949 - -3.2 293,949 - -0.2 293,953 - -1.7 293,953 - -2.5 293,953 - -0.2 293,953 - -1.7 293,953 - -0.2 293,953 - -1.9 293,953 - -1.7 293,953 - -3.5 293,966 - +1.8 293,966 - -1.2 293,966 - -0.2 293,966 - +1.8 293,968 - -1.2 293,989 - -2.7 293,989 - +1.7 293,989 - -0.2 294,026 - -3.0 294,026 - -0.2 294,026 - -3.0 294,032 - -1.7 294,032 - -1.7 294,032 - -2.5 294,032 - -1.0 294,032 - -2.2 294,032 - -2.2 294,032 - -2.2 294,032 - -2.2 294,032 - -1.2
Or see this region's nucleotide sequence