Experiment: m.b. D-Cycloserine 0.032 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HP15_61 and HP15_62 are separated by 41 nucleotides HP15_62 and HP15_63 are separated by 63 nucleotides HP15_63 and HP15_64 are separated by 17 nucleotides
HP15_61: HP15_61 - chain A, alpha-keto acid dehydrogenase-like protein, at 65,530 to 66,759
_61
HP15_62: HP15_62 - hypothetical protein, at 66,801 to 66,905
_62
HP15_63: HP15_63 - 2-oxoisovalerate dehydrogenase, E1 component, beta subunit, at 66,969 to 67,775
_63
HP15_64: HP15_64 - catalytic domain of components of various dehydrogenase complexes, at 67,793 to 69,091
_64
Position (kb)
66
67 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 65.876 kb on - strand, within HP15_61 at 65.896 kb on - strand, within HP15_61 at 65.898 kb on + strand, within HP15_61 at 65.906 kb on - strand, within HP15_61 at 65.906 kb on - strand, within HP15_61 at 65.906 kb on - strand, within HP15_61 at 65.942 kb on + strand, within HP15_61 at 65.950 kb on - strand, within HP15_61 at 65.950 kb on - strand, within HP15_61 at 65.954 kb on + strand, within HP15_61 at 66.025 kb on + strand, within HP15_61 at 66.105 kb on + strand, within HP15_61 at 66.105 kb on + strand, within HP15_61 at 66.105 kb on + strand, within HP15_61 at 66.105 kb on + strand, within HP15_61 at 66.105 kb on + strand, within HP15_61 at 66.113 kb on - strand, within HP15_61 at 66.113 kb on - strand, within HP15_61 at 66.113 kb on - strand, within HP15_61 at 66.113 kb on - strand, within HP15_61 at 66.113 kb on - strand, within HP15_61 at 66.161 kb on - strand, within HP15_61 at 66.192 kb on - strand, within HP15_61 at 66.199 kb on + strand, within HP15_61 at 66.224 kb on - strand, within HP15_61 at 66.225 kb on - strand, within HP15_61 at 66.230 kb on + strand, within HP15_61 at 66.283 kb on - strand, within HP15_61 at 66.447 kb on + strand, within HP15_61 at 66.472 kb on + strand, within HP15_61 at 66.489 kb on + strand, within HP15_61 at 66.489 kb on + strand, within HP15_61 at 66.489 kb on + strand, within HP15_61 at 66.497 kb on - strand, within HP15_61 at 66.497 kb on - strand, within HP15_61 at 66.514 kb on - strand, within HP15_61 at 66.520 kb on + strand, within HP15_61 at 66.521 kb on - strand, within HP15_61 at 66.561 kb on - strand, within HP15_61 at 66.563 kb on + strand, within HP15_61 at 66.563 kb on + strand, within HP15_61 at 66.620 kb on - strand, within HP15_61 at 66.642 kb on + strand at 66.659 kb on + strand at 66.677 kb on - strand at 66.736 kb on - strand at 66.788 kb on + strand at 66.799 kb on - strand at 66.839 kb on - strand, within HP15_62 at 66.844 kb on + strand, within HP15_62 at 66.919 kb on + strand at 66.927 kb on - strand at 66.958 kb on - strand at 66.984 kb on - strand at 66.984 kb on - strand at 67.022 kb on - strand at 67.022 kb on - strand at 67.137 kb on + strand, within HP15_63 at 67.186 kb on - strand, within HP15_63 at 67.441 kb on + strand, within HP15_63 at 67.441 kb on - strand, within HP15_63 at 67.559 kb on - strand, within HP15_63 at 67.570 kb on + strand, within HP15_63 at 67.580 kb on + strand, within HP15_63 at 67.604 kb on + strand, within HP15_63 at 67.612 kb on - strand, within HP15_63 at 67.612 kb on - strand, within HP15_63 at 67.617 kb on - strand, within HP15_63 at 67.689 kb on + strand, within HP15_63 at 67.692 kb on - strand, within HP15_63 at 67.882 kb on + strand at 67.898 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction m.b. D-Cycloserine 0.032 mg/ml remove 65,876 - HP15_61 0.28 -1.0 65,896 - HP15_61 0.30 -0.2 65,898 + HP15_61 0.30 -0.2 65,906 - HP15_61 0.31 -0.1 65,906 - HP15_61 0.31 -0.2 65,906 - HP15_61 0.31 +1.0 65,942 + HP15_61 0.33 -1.1 65,950 - HP15_61 0.34 -0.2 65,950 - HP15_61 0.34 +1.7 65,954 + HP15_61 0.34 -0.6 66,025 + HP15_61 0.40 -0.5 66,105 + HP15_61 0.47 -0.6 66,105 + HP15_61 0.47 -0.8 66,105 + HP15_61 0.47 -0.7 66,105 + HP15_61 0.47 -0.1 66,105 + HP15_61 0.47 +0.8 66,113 - HP15_61 0.47 -2.5 66,113 - HP15_61 0.47 +0.7 66,113 - HP15_61 0.47 +0.1 66,113 - HP15_61 0.47 +0.2 66,113 - HP15_61 0.47 -0.3 66,161 - HP15_61 0.51 +0.4 66,192 - HP15_61 0.54 -0.3 66,199 + HP15_61 0.54 -0.1 66,224 - HP15_61 0.56 -0.0 66,225 - HP15_61 0.57 -0.4 66,230 + HP15_61 0.57 +0.1 66,283 - HP15_61 0.61 +1.3 66,447 + HP15_61 0.75 -0.3 66,472 + HP15_61 0.77 -0.9 66,489 + HP15_61 0.78 -0.7 66,489 + HP15_61 0.78 +0.5 66,489 + HP15_61 0.78 +0.2 66,497 - HP15_61 0.79 -0.3 66,497 - HP15_61 0.79 +0.1 66,514 - HP15_61 0.80 +0.4 66,520 + HP15_61 0.80 +0.1 66,521 - HP15_61 0.81 -0.5 66,561 - HP15_61 0.84 +0.4 66,563 + HP15_61 0.84 -0.3 66,563 + HP15_61 0.84 +0.1 66,620 - HP15_61 0.89 -1.0 66,642 + +0.5 66,659 + +0.1 66,677 - +0.3 66,736 - +0.1 66,788 + +3.5 66,799 - +0.6 66,839 - HP15_62 0.36 +1.0 66,844 + HP15_62 0.41 +0.6 66,919 + -1.1 66,927 - +0.5 66,958 - +0.4 66,984 - -0.7 66,984 - +0.4 67,022 - +0.5 67,022 - +0.1 67,137 + HP15_63 0.21 +0.7 67,186 - HP15_63 0.27 +0.8 67,441 + HP15_63 0.58 +0.1 67,441 - HP15_63 0.58 -0.8 67,559 - HP15_63 0.73 -0.3 67,570 + HP15_63 0.74 +0.4 67,580 + HP15_63 0.76 -0.1 67,604 + HP15_63 0.79 -0.7 67,612 - HP15_63 0.80 +1.0 67,612 - HP15_63 0.80 -0.1 67,617 - HP15_63 0.80 +0.8 67,689 + HP15_63 0.89 -0.6 67,692 - HP15_63 0.90 +1.0 67,882 + -1.2 67,898 + -0.3
Or see this region's nucleotide sequence