Experiment: m.b. D-Cycloserine 0.032 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HP15_4115 and HP15_4116 are separated by 106 nucleotides HP15_4116 and HP15_4117 are separated by 97 nucleotides HP15_4117 and HP15_4118 overlap by 4 nucleotides HP15_4118 and HP15_4119 are separated by 216 nucleotides HP15_4119 and HP15_4120 are separated by 141 nucleotides
HP15_4115: HP15_4115 - sensory box/GGDEF/EAL family protein, at 4,349,658 to 4,352,093
_4115
HP15_4116: HP15_4116 - SirA-like protein, at 4,352,200 to 4,352,334
_4116
HP15_4117: HP15_4117 - membrane or secreted protein, at 4,352,432 to 4,352,560
_4117
HP15_4118: HP15_4118 - formate dehydrogenase, gamma subunit, at 4,352,557 to 4,353,600
_4118
HP15_4119: HP15_4119 - 4Fe-4S ferredoxin, iron-sulfur binding domain protein, at 4,353,817 to 4,354,299
_4119
HP15_4120: HP15_4120 - secreted protein containing molybdopterin oxidoreductase / molybdopterin dinucleotide-binding region, at 4,354,441 to 4,357,326
_4120
Position (kb)
4352
4353
4354 Strain fitness (log2 ratio)
-1
0
1
2 at 4351.605 kb on - strand, within HP15_4115 at 4351.605 kb on - strand, within HP15_4115 at 4351.668 kb on + strand, within HP15_4115 at 4351.676 kb on - strand, within HP15_4115 at 4351.676 kb on - strand, within HP15_4115 at 4351.748 kb on + strand, within HP15_4115 at 4351.756 kb on - strand, within HP15_4115 at 4351.943 kb on + strand at 4351.943 kb on + strand at 4351.948 kb on + strand at 4351.951 kb on - strand at 4351.951 kb on - strand at 4351.951 kb on - strand at 4351.984 kb on - strand at 4352.014 kb on + strand at 4352.042 kb on + strand at 4352.089 kb on - strand at 4352.163 kb on + strand at 4352.224 kb on + strand, within HP15_4116 at 4352.295 kb on + strand, within HP15_4116 at 4352.344 kb on + strand at 4352.395 kb on - strand at 4352.395 kb on - strand at 4352.395 kb on - strand at 4352.420 kb on + strand at 4352.420 kb on + strand at 4352.420 kb on + strand at 4352.428 kb on - strand at 4352.433 kb on - strand at 4352.457 kb on + strand, within HP15_4117 at 4352.465 kb on - strand, within HP15_4117 at 4352.684 kb on - strand, within HP15_4118 at 4352.713 kb on - strand, within HP15_4118 at 4352.738 kb on - strand, within HP15_4118 at 4352.857 kb on - strand, within HP15_4118 at 4352.971 kb on + strand, within HP15_4118 at 4353.019 kb on + strand, within HP15_4118 at 4353.051 kb on - strand, within HP15_4118 at 4353.185 kb on - strand, within HP15_4118 at 4353.236 kb on + strand, within HP15_4118 at 4353.244 kb on - strand, within HP15_4118 at 4353.254 kb on + strand, within HP15_4118 at 4353.375 kb on + strand, within HP15_4118 at 4353.383 kb on - strand, within HP15_4118 at 4353.393 kb on - strand, within HP15_4118 at 4353.412 kb on - strand, within HP15_4118 at 4353.604 kb on + strand at 4353.614 kb on - strand at 4353.621 kb on - strand at 4353.644 kb on + strand at 4353.671 kb on + strand at 4353.671 kb on + strand at 4353.671 kb on + strand at 4353.679 kb on - strand at 4353.813 kb on - strand at 4353.847 kb on - strand at 4353.934 kb on + strand, within HP15_4119 at 4354.006 kb on + strand, within HP15_4119 at 4354.124 kb on + strand, within HP15_4119 at 4354.170 kb on + strand, within HP15_4119 at 4354.170 kb on + strand, within HP15_4119 at 4354.170 kb on + strand, within HP15_4119 at 4354.170 kb on + strand, within HP15_4119 at 4354.170 kb on + strand, within HP15_4119 at 4354.180 kb on + strand, within HP15_4119 at 4354.215 kb on + strand, within HP15_4119 at 4354.217 kb on + strand, within HP15_4119 at 4354.217 kb on + strand, within HP15_4119 at 4354.238 kb on - strand, within HP15_4119 at 4354.238 kb on - strand, within HP15_4119 at 4354.284 kb on + strand at 4354.284 kb on + strand at 4354.343 kb on - strand at 4354.426 kb on + strand at 4354.426 kb on + strand at 4354.426 kb on + strand at 4354.469 kb on + strand at 4354.547 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction m.b. D-Cycloserine 0.032 mg/ml remove 4,351,605 - HP15_4115 0.80 +0.0 4,351,605 - HP15_4115 0.80 +0.7 4,351,668 + HP15_4115 0.83 +0.5 4,351,676 - HP15_4115 0.83 +1.8 4,351,676 - HP15_4115 0.83 +0.8 4,351,748 + HP15_4115 0.86 +0.5 4,351,756 - HP15_4115 0.86 -1.3 4,351,943 + +0.1 4,351,943 + -0.3 4,351,948 + -0.2 4,351,951 - +0.5 4,351,951 - +0.2 4,351,951 - +0.7 4,351,984 - -1.2 4,352,014 + +1.0 4,352,042 + -0.3 4,352,089 - +0.3 4,352,163 + -0.8 4,352,224 + HP15_4116 0.18 +0.7 4,352,295 + HP15_4116 0.70 -0.4 4,352,344 + +1.1 4,352,395 - +0.5 4,352,395 - -0.3 4,352,395 - +0.4 4,352,420 + -1.2 4,352,420 + -0.1 4,352,420 + -0.4 4,352,428 - +0.7 4,352,433 - +0.1 4,352,457 + HP15_4117 0.19 +0.6 4,352,465 - HP15_4117 0.26 +0.1 4,352,684 - HP15_4118 0.12 +1.1 4,352,713 - HP15_4118 0.15 +0.7 4,352,738 - HP15_4118 0.17 +0.8 4,352,857 - HP15_4118 0.29 -0.2 4,352,971 + HP15_4118 0.40 +0.3 4,353,019 + HP15_4118 0.44 +1.3 4,353,051 - HP15_4118 0.47 +0.3 4,353,185 - HP15_4118 0.60 +0.0 4,353,236 + HP15_4118 0.65 +0.6 4,353,244 - HP15_4118 0.66 +0.9 4,353,254 + HP15_4118 0.67 -0.1 4,353,375 + HP15_4118 0.78 +1.6 4,353,383 - HP15_4118 0.79 +0.2 4,353,393 - HP15_4118 0.80 +0.7 4,353,412 - HP15_4118 0.82 +1.2 4,353,604 + +0.9 4,353,614 - +0.6 4,353,621 - +0.0 4,353,644 + +1.0 4,353,671 + +1.4 4,353,671 + +1.0 4,353,671 + +1.4 4,353,679 - +0.9 4,353,813 - +0.9 4,353,847 - +1.1 4,353,934 + HP15_4119 0.24 +1.5 4,354,006 + HP15_4119 0.39 +0.7 4,354,124 + HP15_4119 0.64 +0.0 4,354,170 + HP15_4119 0.73 -0.0 4,354,170 + HP15_4119 0.73 +0.8 4,354,170 + HP15_4119 0.73 +0.9 4,354,170 + HP15_4119 0.73 +0.5 4,354,170 + HP15_4119 0.73 +0.6 4,354,180 + HP15_4119 0.75 +0.9 4,354,215 + HP15_4119 0.82 +2.2 4,354,217 + HP15_4119 0.83 +0.8 4,354,217 + HP15_4119 0.83 +0.9 4,354,238 - HP15_4119 0.87 +0.9 4,354,238 - HP15_4119 0.87 +0.5 4,354,284 + +0.7 4,354,284 + +0.4 4,354,343 - +1.4 4,354,426 + +1.7 4,354,426 + +2.3 4,354,426 + +0.6 4,354,469 + +0.5 4,354,547 - -0.1
Or see this region's nucleotide sequence