Experiment: D-Mannose 10 mg/mL (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HMPREF1078_RS16650 and HMPREF1078_RS16655 are separated by 48 nucleotides HMPREF1078_RS16655 and HMPREF1078_RS16660 are separated by 27 nucleotides HMPREF1078_RS16660 and HMPREF1078_RS16665 are separated by 10 nucleotides
HMPREF1078_RS16650: HMPREF1078_RS16650 - alpha-isopropylmalate synthase regulatory domain-containing protein, at 41,186 to 42,694
_RS16650
HMPREF1078_RS16655: HMPREF1078_RS16655 - 3-isopropylmalate dehydratase small subunit, at 42,743 to 43,330
_RS16655
HMPREF1078_RS16660: HMPREF1078_RS16660 - 3-isopropylmalate dehydratase large subunit, at 43,358 to 44,752
_RS16660
HMPREF1078_RS16665: HMPREF1078_RS16665 - 2-isopropylmalate synthase, at 44,763 to 46,259
_RS16665
Position (kb) 43
44
45 Strain fitness (log2 ratio) -5
-4
-3
-2
-1
0
1 at 42.365 kb on - strand, within HMPREF1078_RS16650 at 42.388 kb on + strand, within HMPREF1078_RS16650 at 42.388 kb on + strand, within HMPREF1078_RS16650 at 42.388 kb on + strand, within HMPREF1078_RS16650 at 42.389 kb on - strand, within HMPREF1078_RS16650 at 42.390 kb on + strand, within HMPREF1078_RS16650 at 42.390 kb on + strand, within HMPREF1078_RS16650 at 42.391 kb on - strand, within HMPREF1078_RS16650 at 42.391 kb on - strand, within HMPREF1078_RS16650 at 42.677 kb on - strand at 42.683 kb on + strand at 42.704 kb on + strand at 42.706 kb on + strand at 42.706 kb on + strand at 42.706 kb on - strand at 42.707 kb on - strand at 42.707 kb on - strand at 42.707 kb on - strand at 42.708 kb on + strand at 42.708 kb on + strand at 42.708 kb on + strand at 42.708 kb on + strand at 42.708 kb on + strand at 42.709 kb on - strand at 42.709 kb on - strand at 42.720 kb on + strand at 42.720 kb on + strand at 42.720 kb on + strand at 42.744 kb on + strand at 42.793 kb on - strand at 42.913 kb on - strand, within HMPREF1078_RS16655 at 43.121 kb on + strand, within HMPREF1078_RS16655 at 43.135 kb on - strand, within HMPREF1078_RS16655 at 43.163 kb on + strand, within HMPREF1078_RS16655 at 43.306 kb on + strand at 43.306 kb on + strand at 43.306 kb on + strand at 43.307 kb on - strand at 43.307 kb on - strand at 43.307 kb on - strand at 43.307 kb on - strand at 43.307 kb on - strand at 43.351 kb on + strand at 43.491 kb on + strand at 43.578 kb on - strand, within HMPREF1078_RS16660 at 43.613 kb on + strand, within HMPREF1078_RS16660 at 43.672 kb on + strand, within HMPREF1078_RS16660 at 43.672 kb on + strand, within HMPREF1078_RS16660 at 43.727 kb on + strand, within HMPREF1078_RS16660 at 43.727 kb on + strand, within HMPREF1078_RS16660 at 43.727 kb on + strand, within HMPREF1078_RS16660 at 43.728 kb on - strand, within HMPREF1078_RS16660 at 43.783 kb on + strand, within HMPREF1078_RS16660 at 43.785 kb on + strand, within HMPREF1078_RS16660 at 43.786 kb on - strand, within HMPREF1078_RS16660 at 43.786 kb on - strand, within HMPREF1078_RS16660 at 43.786 kb on - strand, within HMPREF1078_RS16660 at 43.786 kb on - strand, within HMPREF1078_RS16660 at 43.846 kb on + strand, within HMPREF1078_RS16660 at 43.848 kb on - strand, within HMPREF1078_RS16660 at 43.883 kb on - strand, within HMPREF1078_RS16660 at 43.887 kb on + strand, within HMPREF1078_RS16660 at 43.888 kb on - strand, within HMPREF1078_RS16660 at 43.888 kb on - strand, within HMPREF1078_RS16660 at 43.888 kb on - strand, within HMPREF1078_RS16660 at 43.888 kb on - strand, within HMPREF1078_RS16660 at 43.888 kb on - strand, within HMPREF1078_RS16660 at 43.991 kb on - strand, within HMPREF1078_RS16660 at 44.149 kb on - strand, within HMPREF1078_RS16660 at 44.197 kb on + strand, within HMPREF1078_RS16660 at 44.197 kb on + strand, within HMPREF1078_RS16660 at 44.198 kb on - strand, within HMPREF1078_RS16660 at 44.198 kb on - strand, within HMPREF1078_RS16660 at 44.198 kb on - strand, within HMPREF1078_RS16660 at 44.198 kb on - strand, within HMPREF1078_RS16660 at 44.198 kb on - strand, within HMPREF1078_RS16660 at 44.200 kb on - strand, within HMPREF1078_RS16660 at 44.255 kb on - strand, within HMPREF1078_RS16660 at 44.255 kb on - strand, within HMPREF1078_RS16660 at 44.359 kb on + strand, within HMPREF1078_RS16660 at 44.365 kb on + strand, within HMPREF1078_RS16660 at 44.366 kb on - strand, within HMPREF1078_RS16660 at 44.423 kb on + strand, within HMPREF1078_RS16660 at 44.435 kb on - strand, within HMPREF1078_RS16660 at 44.438 kb on - strand, within HMPREF1078_RS16660 at 44.438 kb on - strand, within HMPREF1078_RS16660 at 44.566 kb on + strand, within HMPREF1078_RS16660 at 44.566 kb on + strand, within HMPREF1078_RS16660 at 44.566 kb on + strand, within HMPREF1078_RS16660 at 44.578 kb on + strand, within HMPREF1078_RS16660 at 44.583 kb on + strand, within HMPREF1078_RS16660 at 44.584 kb on - strand, within HMPREF1078_RS16660 at 44.584 kb on - strand, within HMPREF1078_RS16660 at 44.584 kb on - strand, within HMPREF1078_RS16660 at 44.587 kb on + strand, within HMPREF1078_RS16660 at 44.587 kb on + strand, within HMPREF1078_RS16660 at 44.587 kb on + strand, within HMPREF1078_RS16660 at 44.587 kb on + strand, within HMPREF1078_RS16660 at 44.587 kb on + strand, within HMPREF1078_RS16660 at 44.588 kb on - strand, within HMPREF1078_RS16660 at 44.588 kb on - strand, within HMPREF1078_RS16660 at 44.588 kb on - strand, within HMPREF1078_RS16660 at 44.588 kb on - strand, within HMPREF1078_RS16660 at 44.588 kb on - strand, within HMPREF1078_RS16660 at 44.648 kb on - strand at 44.664 kb on + strand at 44.664 kb on + strand at 44.664 kb on + strand at 44.665 kb on - strand at 44.665 kb on - strand at 44.679 kb on + strand at 44.680 kb on - strand at 44.742 kb on - strand at 44.746 kb on + strand at 44.746 kb on + strand at 44.747 kb on - strand at 44.752 kb on + strand at 44.757 kb on - strand at 44.781 kb on - strand at 44.793 kb on - strand at 44.802 kb on + strand at 44.817 kb on - strand at 44.817 kb on - strand at 44.842 kb on + strand at 44.843 kb on - strand at 44.873 kb on + strand at 44.873 kb on + strand at 44.873 kb on + strand at 44.873 kb on + strand at 44.873 kb on + strand at 44.873 kb on + strand at 44.873 kb on + strand at 44.874 kb on - strand at 44.874 kb on - strand at 44.874 kb on - strand at 44.874 kb on - strand at 44.874 kb on - strand at 44.874 kb on - strand at 44.874 kb on - strand at 44.878 kb on - strand at 44.878 kb on - strand at 44.973 kb on - strand, within HMPREF1078_RS16665 at 44.973 kb on - strand, within HMPREF1078_RS16665 at 45.027 kb on + strand, within HMPREF1078_RS16665 at 45.028 kb on - strand, within HMPREF1078_RS16665 at 45.028 kb on - strand, within HMPREF1078_RS16665 at 45.029 kb on + strand, within HMPREF1078_RS16665 at 45.029 kb on + strand, within HMPREF1078_RS16665 at 45.029 kb on + strand, within HMPREF1078_RS16665 at 45.029 kb on + strand, within HMPREF1078_RS16665 at 45.030 kb on - strand, within HMPREF1078_RS16665 at 45.030 kb on - strand, within HMPREF1078_RS16665 at 45.082 kb on - strand, within HMPREF1078_RS16665 at 45.098 kb on + strand, within HMPREF1078_RS16665 at 45.099 kb on - strand, within HMPREF1078_RS16665 at 45.140 kb on + strand, within HMPREF1078_RS16665 at 45.155 kb on + strand, within HMPREF1078_RS16665 at 45.155 kb on + strand, within HMPREF1078_RS16665 at 45.193 kb on + strand, within HMPREF1078_RS16665 at 45.307 kb on - strand, within HMPREF1078_RS16665 at 45.393 kb on - strand, within HMPREF1078_RS16665 at 45.450 kb on - strand, within HMPREF1078_RS16665 at 45.476 kb on + strand, within HMPREF1078_RS16665 at 45.483 kb on - strand, within HMPREF1078_RS16665 at 45.489 kb on - strand, within HMPREF1078_RS16665 at 45.489 kb on - strand, within HMPREF1078_RS16665 at 45.489 kb on - strand, within HMPREF1078_RS16665 at 45.546 kb on - strand, within HMPREF1078_RS16665 at 45.564 kb on + strand, within HMPREF1078_RS16665 at 45.565 kb on - strand, within HMPREF1078_RS16665 at 45.567 kb on - strand, within HMPREF1078_RS16665 at 45.621 kb on - strand, within HMPREF1078_RS16665 at 45.660 kb on - strand, within HMPREF1078_RS16665 at 45.668 kb on + strand, within HMPREF1078_RS16665 at 45.688 kb on - strand, within HMPREF1078_RS16665
Per-strain Table
Position Strand Gene LocusTag Fraction D-Mannose 10 mg/mL (C) remove 42,365 - HMPREF1078_RS16650 0.78 -3.8 42,388 + HMPREF1078_RS16650 0.80 -1.9 42,388 + HMPREF1078_RS16650 0.80 -1.5 42,388 + HMPREF1078_RS16650 0.80 -1.8 42,389 - HMPREF1078_RS16650 0.80 -2.9 42,390 + HMPREF1078_RS16650 0.80 -0.6 42,390 + HMPREF1078_RS16650 0.80 -2.2 42,391 - HMPREF1078_RS16650 0.80 -1.8 42,391 - HMPREF1078_RS16650 0.80 -3.8 42,677 - -2.5 42,683 + -3.6 42,704 + -2.6 42,706 + -4.6 42,706 + -3.8 42,706 - +0.4 42,707 - -0.2 42,707 - +0.8 42,707 - +0.2 42,708 + -4.0 42,708 + -1.9 42,708 + -2.9 42,708 + -3.8 42,708 + -3.8 42,709 - +1.1 42,709 - +0.2 42,720 + -3.5 42,720 + -3.9 42,720 + -2.7 42,744 + -3.4 42,793 - -2.2 42,913 - HMPREF1078_RS16655 0.29 -2.7 43,121 + HMPREF1078_RS16655 0.64 -4.5 43,135 - HMPREF1078_RS16655 0.67 -1.7 43,163 + HMPREF1078_RS16655 0.71 -2.5 43,306 + -0.1 43,306 + -3.1 43,306 + -2.0 43,307 - -2.4 43,307 - -3.0 43,307 - -3.3 43,307 - -3.1 43,307 - -2.0 43,351 + -4.3 43,491 + -2.6 43,578 - HMPREF1078_RS16660 0.16 -2.1 43,613 + HMPREF1078_RS16660 0.18 -3.9 43,672 + HMPREF1078_RS16660 0.23 -3.4 43,672 + HMPREF1078_RS16660 0.23 -4.3 43,727 + HMPREF1078_RS16660 0.26 -4.6 43,727 + HMPREF1078_RS16660 0.26 -1.2 43,727 + HMPREF1078_RS16660 0.26 -3.1 43,728 - HMPREF1078_RS16660 0.27 -3.4 43,783 + HMPREF1078_RS16660 0.30 -3.1 43,785 + HMPREF1078_RS16660 0.31 -4.7 43,786 - HMPREF1078_RS16660 0.31 -4.5 43,786 - HMPREF1078_RS16660 0.31 -2.6 43,786 - HMPREF1078_RS16660 0.31 -3.2 43,786 - HMPREF1078_RS16660 0.31 -1.7 43,846 + HMPREF1078_RS16660 0.35 -3.8 43,848 - HMPREF1078_RS16660 0.35 -4.1 43,883 - HMPREF1078_RS16660 0.38 -1.7 43,887 + HMPREF1078_RS16660 0.38 -2.0 43,888 - HMPREF1078_RS16660 0.38 -4.2 43,888 - HMPREF1078_RS16660 0.38 -3.1 43,888 - HMPREF1078_RS16660 0.38 +0.4 43,888 - HMPREF1078_RS16660 0.38 -3.1 43,888 - HMPREF1078_RS16660 0.38 -3.6 43,991 - HMPREF1078_RS16660 0.45 -3.1 44,149 - HMPREF1078_RS16660 0.57 -1.5 44,197 + HMPREF1078_RS16660 0.60 -4.1 44,197 + HMPREF1078_RS16660 0.60 -2.8 44,198 - HMPREF1078_RS16660 0.60 -2.9 44,198 - HMPREF1078_RS16660 0.60 -2.8 44,198 - HMPREF1078_RS16660 0.60 -2.4 44,198 - HMPREF1078_RS16660 0.60 -3.5 44,198 - HMPREF1078_RS16660 0.60 -3.2 44,200 - HMPREF1078_RS16660 0.60 -1.5 44,255 - HMPREF1078_RS16660 0.64 -2.8 44,255 - HMPREF1078_RS16660 0.64 -2.5 44,359 + HMPREF1078_RS16660 0.72 -5.1 44,365 + HMPREF1078_RS16660 0.72 -2.4 44,366 - HMPREF1078_RS16660 0.72 -3.7 44,423 + HMPREF1078_RS16660 0.76 -2.4 44,435 - HMPREF1078_RS16660 0.77 -1.6 44,438 - HMPREF1078_RS16660 0.77 -2.6 44,438 - HMPREF1078_RS16660 0.77 -4.0 44,566 + HMPREF1078_RS16660 0.87 -1.1 44,566 + HMPREF1078_RS16660 0.87 -3.2 44,566 + HMPREF1078_RS16660 0.87 -3.6 44,578 + HMPREF1078_RS16660 0.87 -4.4 44,583 + HMPREF1078_RS16660 0.88 -3.1 44,584 - HMPREF1078_RS16660 0.88 -5.0 44,584 - HMPREF1078_RS16660 0.88 -3.8 44,584 - HMPREF1078_RS16660 0.88 -2.2 44,587 + HMPREF1078_RS16660 0.88 -1.7 44,587 + HMPREF1078_RS16660 0.88 -3.0 44,587 + HMPREF1078_RS16660 0.88 -1.1 44,587 + HMPREF1078_RS16660 0.88 -2.0 44,587 + HMPREF1078_RS16660 0.88 -2.1 44,588 - HMPREF1078_RS16660 0.88 -3.4 44,588 - HMPREF1078_RS16660 0.88 -4.0 44,588 - HMPREF1078_RS16660 0.88 -3.7 44,588 - HMPREF1078_RS16660 0.88 -2.2 44,588 - HMPREF1078_RS16660 0.88 -4.3 44,648 - -3.3 44,664 + -2.8 44,664 + -1.1 44,664 + -1.6 44,665 - -4.7 44,665 - -3.7 44,679 + -3.8 44,680 - -4.3 44,742 - -0.6 44,746 + -3.7 44,746 + -3.6 44,747 - -1.1 44,752 + -0.2 44,757 - -4.4 44,781 - -1.0 44,793 - -4.0 44,802 + -3.5 44,817 - -1.2 44,817 - -3.3 44,842 + -3.6 44,843 - -2.7 44,873 + -3.3 44,873 + -4.2 44,873 + -3.2 44,873 + -2.6 44,873 + -2.6 44,873 + -3.6 44,873 + -2.2 44,874 - -2.4 44,874 - -2.3 44,874 - -3.5 44,874 - -2.0 44,874 - -3.7 44,874 - -2.3 44,874 - -2.5 44,878 - -0.5 44,878 - -2.0 44,973 - HMPREF1078_RS16665 0.14 -1.5 44,973 - HMPREF1078_RS16665 0.14 -3.0 45,027 + HMPREF1078_RS16665 0.18 -5.0 45,028 - HMPREF1078_RS16665 0.18 -2.0 45,028 - HMPREF1078_RS16665 0.18 -1.4 45,029 + HMPREF1078_RS16665 0.18 -1.5 45,029 + HMPREF1078_RS16665 0.18 -0.2 45,029 + HMPREF1078_RS16665 0.18 -2.3 45,029 + HMPREF1078_RS16665 0.18 -2.1 45,030 - HMPREF1078_RS16665 0.18 -3.7 45,030 - HMPREF1078_RS16665 0.18 -3.7 45,082 - HMPREF1078_RS16665 0.21 -3.3 45,098 + HMPREF1078_RS16665 0.22 -1.0 45,099 - HMPREF1078_RS16665 0.22 -2.0 45,140 + HMPREF1078_RS16665 0.25 -2.9 45,155 + HMPREF1078_RS16665 0.26 -2.6 45,155 + HMPREF1078_RS16665 0.26 -2.5 45,193 + HMPREF1078_RS16665 0.29 -0.5 45,307 - HMPREF1078_RS16665 0.36 -3.6 45,393 - HMPREF1078_RS16665 0.42 -2.1 45,450 - HMPREF1078_RS16665 0.46 -4.0 45,476 + HMPREF1078_RS16665 0.48 -4.8 45,483 - HMPREF1078_RS16665 0.48 -2.8 45,489 - HMPREF1078_RS16665 0.48 -3.8 45,489 - HMPREF1078_RS16665 0.48 -3.8 45,489 - HMPREF1078_RS16665 0.48 -1.2 45,546 - HMPREF1078_RS16665 0.52 -2.4 45,564 + HMPREF1078_RS16665 0.54 -5.7 45,565 - HMPREF1078_RS16665 0.54 -2.0 45,567 - HMPREF1078_RS16665 0.54 -3.6 45,621 - HMPREF1078_RS16665 0.57 -2.3 45,660 - HMPREF1078_RS16665 0.60 -1.6 45,668 + HMPREF1078_RS16665 0.60 -2.1 45,688 - HMPREF1078_RS16665 0.62 -2.9
Or see this region's nucleotide sequence