Experiment: D-Mannose 10 mg/mL (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HMPREF1078_RS05270 and HMPREF1078_RS05275 are separated by 140 nucleotides HMPREF1078_RS05275 and HMPREF1078_RS05280 are separated by 189 nucleotides HMPREF1078_RS05280 and HMPREF1078_RS05285 are separated by 316 nucleotides
HMPREF1078_RS05270: HMPREF1078_RS05270 - TrpB-like pyridoxal phosphate-dependent enzyme, at 324,637 to 326,001
_RS05270
HMPREF1078_RS05275: HMPREF1078_RS05275 - DUF3836 domain-containing protein, at 326,142 to 326,552
_RS05275
HMPREF1078_RS05280: HMPREF1078_RS05280 - helix-turn-helix transcriptional regulator, at 326,742 to 326,954
_RS05280
HMPREF1078_RS05285: HMPREF1078_RS05285 - DUF2975 domain-containing protein, at 327,271 to 327,936
_RS05285
Position (kb) 326
327 Strain fitness (log2 ratio) -6
-5
-4
-3
-2
-1
0
1
2
3
4 at 325.815 kb on + strand, within HMPREF1078_RS05270 at 325.857 kb on + strand, within HMPREF1078_RS05270 at 325.857 kb on + strand, within HMPREF1078_RS05270 at 325.857 kb on + strand, within HMPREF1078_RS05270 at 325.858 kb on - strand, within HMPREF1078_RS05270 at 325.939 kb on + strand at 325.939 kb on + strand at 325.939 kb on + strand at 325.995 kb on + strand at 325.995 kb on + strand at 326.011 kb on - strand at 326.011 kb on - strand at 326.011 kb on - strand at 326.071 kb on + strand at 326.120 kb on - strand at 326.126 kb on + strand at 326.126 kb on + strand at 326.127 kb on - strand at 326.127 kb on - strand at 326.131 kb on + strand at 326.136 kb on + strand at 326.136 kb on + strand at 326.137 kb on - strand at 326.137 kb on - strand at 326.140 kb on + strand at 326.140 kb on + strand at 326.141 kb on - strand at 326.141 kb on - strand at 326.141 kb on - strand at 326.143 kb on + strand at 326.143 kb on + strand at 326.143 kb on + strand at 326.144 kb on - strand at 326.144 kb on - strand at 326.144 kb on - strand at 326.161 kb on + strand at 326.162 kb on - strand at 326.162 kb on - strand at 326.184 kb on - strand, within HMPREF1078_RS05275 at 326.184 kb on - strand, within HMPREF1078_RS05275 at 326.197 kb on - strand, within HMPREF1078_RS05275 at 326.197 kb on - strand, within HMPREF1078_RS05275 at 326.197 kb on - strand, within HMPREF1078_RS05275 at 326.197 kb on - strand, within HMPREF1078_RS05275 at 326.267 kb on - strand, within HMPREF1078_RS05275 at 326.272 kb on + strand, within HMPREF1078_RS05275 at 326.272 kb on + strand, within HMPREF1078_RS05275 at 326.284 kb on + strand, within HMPREF1078_RS05275 at 326.287 kb on + strand, within HMPREF1078_RS05275 at 326.287 kb on + strand, within HMPREF1078_RS05275 at 326.287 kb on + strand, within HMPREF1078_RS05275 at 326.307 kb on - strand, within HMPREF1078_RS05275 at 326.312 kb on + strand, within HMPREF1078_RS05275 at 326.313 kb on - strand, within HMPREF1078_RS05275 at 326.313 kb on - strand, within HMPREF1078_RS05275 at 326.323 kb on + strand, within HMPREF1078_RS05275 at 326.323 kb on + strand, within HMPREF1078_RS05275 at 326.375 kb on + strand, within HMPREF1078_RS05275 at 326.376 kb on - strand, within HMPREF1078_RS05275 at 326.376 kb on - strand, within HMPREF1078_RS05275 at 326.406 kb on + strand, within HMPREF1078_RS05275 at 326.426 kb on + strand, within HMPREF1078_RS05275 at 326.432 kb on + strand, within HMPREF1078_RS05275 at 326.450 kb on + strand, within HMPREF1078_RS05275 at 326.450 kb on + strand, within HMPREF1078_RS05275 at 326.455 kb on + strand, within HMPREF1078_RS05275 at 326.455 kb on + strand, within HMPREF1078_RS05275 at 326.456 kb on - strand, within HMPREF1078_RS05275 at 326.456 kb on - strand, within HMPREF1078_RS05275 at 326.456 kb on - strand, within HMPREF1078_RS05275 at 326.456 kb on - strand, within HMPREF1078_RS05275 at 326.456 kb on - strand, within HMPREF1078_RS05275 at 326.456 kb on - strand, within HMPREF1078_RS05275 at 326.461 kb on + strand, within HMPREF1078_RS05275 at 326.461 kb on + strand, within HMPREF1078_RS05275 at 326.461 kb on + strand, within HMPREF1078_RS05275 at 326.461 kb on + strand, within HMPREF1078_RS05275 at 326.461 kb on + strand, within HMPREF1078_RS05275 at 326.461 kb on + strand, within HMPREF1078_RS05275 at 326.462 kb on - strand, within HMPREF1078_RS05275 at 326.462 kb on - strand, within HMPREF1078_RS05275 at 326.462 kb on - strand, within HMPREF1078_RS05275 at 326.462 kb on - strand, within HMPREF1078_RS05275 at 326.495 kb on + strand, within HMPREF1078_RS05275 at 326.496 kb on - strand, within HMPREF1078_RS05275 at 326.507 kb on + strand, within HMPREF1078_RS05275 at 326.508 kb on - strand, within HMPREF1078_RS05275 at 326.508 kb on - strand, within HMPREF1078_RS05275 at 326.508 kb on - strand, within HMPREF1078_RS05275 at 326.508 kb on - strand, within HMPREF1078_RS05275 at 326.508 kb on - strand, within HMPREF1078_RS05275 at 326.536 kb on - strand at 326.552 kb on + strand at 326.552 kb on + strand at 326.552 kb on + strand at 326.553 kb on - strand at 326.554 kb on + strand at 326.555 kb on - strand at 326.555 kb on - strand at 326.555 kb on - strand at 326.555 kb on - strand at 326.562 kb on - strand at 326.562 kb on - strand at 326.596 kb on + strand at 326.600 kb on + strand at 326.600 kb on + strand at 326.600 kb on + strand at 326.603 kb on + strand at 326.603 kb on + strand at 326.631 kb on - strand at 326.646 kb on - strand at 326.686 kb on + strand at 326.686 kb on + strand at 326.687 kb on - strand at 326.688 kb on + strand at 326.700 kb on + strand at 326.700 kb on + strand at 326.700 kb on + strand at 326.708 kb on + strand at 326.770 kb on - strand, within HMPREF1078_RS05280 at 326.770 kb on - strand, within HMPREF1078_RS05280 at 326.798 kb on + strand, within HMPREF1078_RS05280 at 326.828 kb on + strand, within HMPREF1078_RS05280 at 326.874 kb on - strand, within HMPREF1078_RS05280 at 326.883 kb on - strand, within HMPREF1078_RS05280 at 326.883 kb on - strand, within HMPREF1078_RS05280 at 326.940 kb on - strand at 326.947 kb on - strand at 326.948 kb on + strand at 326.982 kb on + strand at 327.063 kb on - strand at 327.075 kb on + strand at 327.075 kb on + strand at 327.078 kb on + strand at 327.078 kb on + strand at 327.081 kb on + strand at 327.081 kb on + strand at 327.081 kb on + strand at 327.082 kb on - strand at 327.083 kb on + strand at 327.083 kb on + strand at 327.083 kb on + strand at 327.086 kb on + strand at 327.086 kb on + strand at 327.087 kb on - strand at 327.087 kb on - strand at 327.104 kb on + strand at 327.122 kb on + strand at 327.122 kb on + strand at 327.131 kb on + strand at 327.153 kb on + strand at 327.158 kb on + strand at 327.190 kb on + strand at 327.202 kb on + strand at 327.206 kb on + strand at 327.228 kb on + strand at 327.272 kb on + strand at 327.439 kb on + strand, within HMPREF1078_RS05285 at 327.444 kb on + strand, within HMPREF1078_RS05285 at 327.444 kb on + strand, within HMPREF1078_RS05285 at 327.444 kb on + strand, within HMPREF1078_RS05285 at 327.445 kb on - strand, within HMPREF1078_RS05285 at 327.446 kb on + strand, within HMPREF1078_RS05285 at 327.446 kb on + strand, within HMPREF1078_RS05285 at 327.446 kb on + strand, within HMPREF1078_RS05285 at 327.446 kb on + strand, within HMPREF1078_RS05285 at 327.446 kb on + strand, within HMPREF1078_RS05285 at 327.447 kb on - strand, within HMPREF1078_RS05285 at 327.447 kb on - strand, within HMPREF1078_RS05285 at 327.447 kb on - strand, within HMPREF1078_RS05285 at 327.447 kb on - strand, within HMPREF1078_RS05285 at 327.460 kb on + strand, within HMPREF1078_RS05285 at 327.461 kb on - strand, within HMPREF1078_RS05285 at 327.505 kb on + strand, within HMPREF1078_RS05285 at 327.505 kb on + strand, within HMPREF1078_RS05285 at 327.520 kb on + strand, within HMPREF1078_RS05285 at 327.555 kb on + strand, within HMPREF1078_RS05285 at 327.577 kb on + strand, within HMPREF1078_RS05285 at 327.601 kb on + strand, within HMPREF1078_RS05285 at 327.601 kb on + strand, within HMPREF1078_RS05285 at 327.603 kb on + strand, within HMPREF1078_RS05285 at 327.613 kb on + strand, within HMPREF1078_RS05285 at 327.613 kb on + strand, within HMPREF1078_RS05285 at 327.617 kb on + strand, within HMPREF1078_RS05285 at 327.617 kb on + strand, within HMPREF1078_RS05285 at 327.618 kb on - strand, within HMPREF1078_RS05285 at 327.666 kb on + strand, within HMPREF1078_RS05285 at 327.666 kb on + strand, within HMPREF1078_RS05285 at 327.667 kb on - strand, within HMPREF1078_RS05285 at 327.667 kb on - strand, within HMPREF1078_RS05285 at 327.706 kb on + strand, within HMPREF1078_RS05285 at 327.711 kb on + strand, within HMPREF1078_RS05285 at 327.711 kb on + strand, within HMPREF1078_RS05285 at 327.742 kb on + strand, within HMPREF1078_RS05285 at 327.747 kb on + strand, within HMPREF1078_RS05285 at 327.747 kb on + strand, within HMPREF1078_RS05285 at 327.764 kb on - strand, within HMPREF1078_RS05285 at 327.777 kb on + strand, within HMPREF1078_RS05285 at 327.777 kb on + strand, within HMPREF1078_RS05285 at 327.941 kb on + strand at 327.941 kb on + strand at 327.942 kb on - strand at 327.942 kb on - strand at 327.942 kb on - strand at 327.944 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction D-Mannose 10 mg/mL (C) remove 325,815 + HMPREF1078_RS05270 0.86 +0.5 325,857 + HMPREF1078_RS05270 0.89 -1.4 325,857 + HMPREF1078_RS05270 0.89 +0.2 325,857 + HMPREF1078_RS05270 0.89 -0.4 325,858 - HMPREF1078_RS05270 0.89 -0.5 325,939 + +0.2 325,939 + -0.7 325,939 + +1.1 325,995 + -0.1 325,995 + +1.1 326,011 - -2.1 326,011 - -0.1 326,011 - +0.1 326,071 + +0.5 326,120 - +0.5 326,126 + -0.2 326,126 + -1.5 326,127 - -0.1 326,127 - -1.1 326,131 + +0.6 326,136 + -0.2 326,136 + -0.0 326,137 - -0.8 326,137 - -0.1 326,140 + -1.1 326,140 + +0.8 326,141 - -0.5 326,141 - +0.5 326,141 - +0.6 326,143 + -2.6 326,143 + +0.9 326,143 + +0.0 326,144 - -0.8 326,144 - +0.7 326,144 - +0.3 326,161 + -0.1 326,162 - -1.2 326,162 - +0.2 326,184 - HMPREF1078_RS05275 0.10 -0.1 326,184 - HMPREF1078_RS05275 0.10 -1.3 326,197 - HMPREF1078_RS05275 0.13 +0.2 326,197 - HMPREF1078_RS05275 0.13 +0.7 326,197 - HMPREF1078_RS05275 0.13 -0.3 326,197 - HMPREF1078_RS05275 0.13 -1.4 326,267 - HMPREF1078_RS05275 0.30 -0.2 326,272 + HMPREF1078_RS05275 0.32 -1.3 326,272 + HMPREF1078_RS05275 0.32 -2.1 326,284 + HMPREF1078_RS05275 0.35 -0.8 326,287 + HMPREF1078_RS05275 0.35 -0.1 326,287 + HMPREF1078_RS05275 0.35 +0.2 326,287 + HMPREF1078_RS05275 0.35 +0.5 326,307 - HMPREF1078_RS05275 0.40 -0.4 326,312 + HMPREF1078_RS05275 0.41 -0.4 326,313 - HMPREF1078_RS05275 0.42 -1.0 326,313 - HMPREF1078_RS05275 0.42 -0.4 326,323 + HMPREF1078_RS05275 0.44 +0.5 326,323 + HMPREF1078_RS05275 0.44 -0.6 326,375 + HMPREF1078_RS05275 0.57 -1.3 326,376 - HMPREF1078_RS05275 0.57 +0.1 326,376 - HMPREF1078_RS05275 0.57 +0.1 326,406 + HMPREF1078_RS05275 0.64 -0.6 326,426 + HMPREF1078_RS05275 0.69 +0.4 326,432 + HMPREF1078_RS05275 0.71 +2.0 326,450 + HMPREF1078_RS05275 0.75 +3.8 326,450 + HMPREF1078_RS05275 0.75 -1.3 326,455 + HMPREF1078_RS05275 0.76 +0.2 326,455 + HMPREF1078_RS05275 0.76 -1.4 326,456 - HMPREF1078_RS05275 0.76 +0.7 326,456 - HMPREF1078_RS05275 0.76 -0.9 326,456 - HMPREF1078_RS05275 0.76 +0.8 326,456 - HMPREF1078_RS05275 0.76 -0.4 326,456 - HMPREF1078_RS05275 0.76 -0.0 326,456 - HMPREF1078_RS05275 0.76 +0.2 326,461 + HMPREF1078_RS05275 0.78 -1.0 326,461 + HMPREF1078_RS05275 0.78 -1.3 326,461 + HMPREF1078_RS05275 0.78 +0.5 326,461 + HMPREF1078_RS05275 0.78 -1.2 326,461 + HMPREF1078_RS05275 0.78 +1.7 326,461 + HMPREF1078_RS05275 0.78 -0.8 326,462 - HMPREF1078_RS05275 0.78 +1.1 326,462 - HMPREF1078_RS05275 0.78 -0.5 326,462 - HMPREF1078_RS05275 0.78 +1.4 326,462 - HMPREF1078_RS05275 0.78 +0.4 326,495 + HMPREF1078_RS05275 0.86 -0.1 326,496 - HMPREF1078_RS05275 0.86 -0.3 326,507 + HMPREF1078_RS05275 0.89 +0.5 326,508 - HMPREF1078_RS05275 0.89 +1.8 326,508 - HMPREF1078_RS05275 0.89 -0.5 326,508 - HMPREF1078_RS05275 0.89 -0.9 326,508 - HMPREF1078_RS05275 0.89 -0.1 326,508 - HMPREF1078_RS05275 0.89 -0.5 326,536 - +0.3 326,552 + +0.6 326,552 + -0.5 326,552 + +0.2 326,553 - -1.6 326,554 + -3.3 326,555 - +0.1 326,555 - +2.3 326,555 - -1.5 326,555 - +0.3 326,562 - -0.2 326,562 - -0.3 326,596 + +0.1 326,600 + -0.9 326,600 + +0.1 326,600 + -2.9 326,603 + -1.8 326,603 + +0.3 326,631 - -0.9 326,646 - -0.5 326,686 + +1.0 326,686 + -1.3 326,687 - +0.5 326,688 + -0.0 326,700 + +0.4 326,700 + -1.4 326,700 + +2.0 326,708 + +1.0 326,770 - HMPREF1078_RS05280 0.13 -2.0 326,770 - HMPREF1078_RS05280 0.13 -3.8 326,798 + HMPREF1078_RS05280 0.26 -3.2 326,828 + HMPREF1078_RS05280 0.40 -4.3 326,874 - HMPREF1078_RS05280 0.62 -3.3 326,883 - HMPREF1078_RS05280 0.66 -5.1 326,883 - HMPREF1078_RS05280 0.66 -2.4 326,940 - -3.4 326,947 - -2.7 326,948 + -4.6 326,982 + -2.3 327,063 - -0.5 327,075 + -3.3 327,075 + -3.9 327,078 + -2.2 327,078 + -3.2 327,081 + -4.1 327,081 + -2.5 327,081 + -1.4 327,082 - -0.6 327,083 + -4.0 327,083 + -2.6 327,083 + -4.3 327,086 + -2.8 327,086 + -1.0 327,087 - +0.7 327,087 - +0.2 327,104 + -3.6 327,122 + -3.2 327,122 + -2.8 327,131 + -2.4 327,153 + -4.5 327,158 + -2.6 327,190 + -4.7 327,202 + -4.3 327,206 + -1.4 327,228 + -3.4 327,272 + -2.7 327,439 + HMPREF1078_RS05285 0.25 -1.6 327,444 + HMPREF1078_RS05285 0.26 -3.0 327,444 + HMPREF1078_RS05285 0.26 -2.0 327,444 + HMPREF1078_RS05285 0.26 -1.4 327,445 - HMPREF1078_RS05285 0.26 -0.1 327,446 + HMPREF1078_RS05285 0.26 -2.3 327,446 + HMPREF1078_RS05285 0.26 -1.6 327,446 + HMPREF1078_RS05285 0.26 -1.9 327,446 + HMPREF1078_RS05285 0.26 -4.8 327,446 + HMPREF1078_RS05285 0.26 -5.5 327,447 - HMPREF1078_RS05285 0.26 +0.2 327,447 - HMPREF1078_RS05285 0.26 +1.3 327,447 - HMPREF1078_RS05285 0.26 +2.0 327,447 - HMPREF1078_RS05285 0.26 -2.6 327,460 + HMPREF1078_RS05285 0.28 -4.1 327,461 - HMPREF1078_RS05285 0.29 +0.2 327,505 + HMPREF1078_RS05285 0.35 -4.6 327,505 + HMPREF1078_RS05285 0.35 -2.3 327,520 + HMPREF1078_RS05285 0.37 -2.2 327,555 + HMPREF1078_RS05285 0.43 -0.8 327,577 + HMPREF1078_RS05285 0.46 -2.9 327,601 + HMPREF1078_RS05285 0.50 -3.1 327,601 + HMPREF1078_RS05285 0.50 -4.1 327,603 + HMPREF1078_RS05285 0.50 -2.4 327,613 + HMPREF1078_RS05285 0.51 -0.1 327,613 + HMPREF1078_RS05285 0.51 -3.2 327,617 + HMPREF1078_RS05285 0.52 -0.5 327,617 + HMPREF1078_RS05285 0.52 -1.6 327,618 - HMPREF1078_RS05285 0.52 -0.3 327,666 + HMPREF1078_RS05285 0.59 -3.8 327,666 + HMPREF1078_RS05285 0.59 -3.7 327,667 - HMPREF1078_RS05285 0.59 +0.2 327,667 - HMPREF1078_RS05285 0.59 +0.9 327,706 + HMPREF1078_RS05285 0.65 -5.8 327,711 + HMPREF1078_RS05285 0.66 -2.1 327,711 + HMPREF1078_RS05285 0.66 -3.2 327,742 + HMPREF1078_RS05285 0.71 -3.4 327,747 + HMPREF1078_RS05285 0.71 -3.2 327,747 + HMPREF1078_RS05285 0.71 -2.0 327,764 - HMPREF1078_RS05285 0.74 +2.1 327,777 + HMPREF1078_RS05285 0.76 -4.2 327,777 + HMPREF1078_RS05285 0.76 -1.7 327,941 + -1.6 327,941 + -3.6 327,942 - -0.5 327,942 - +0.5 327,942 - -1.2 327,944 - -0.9
Or see this region's nucleotide sequence