Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3292

Experiment: L-Glutamine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3290c and Rv3291c are separated by 50 nucleotidesRv3291c and Rv3292 are separated by 30 nucleotidesRv3292 and Rv3293 are separated by 26 nucleotides Rv3290c: Rv3290c - Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase), at 3,670,445 to 3,671,794 Rv3290c Rv3291c: Rv3291c - Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family), at 3,671,845 to 3,672,297 Rv3291c Rv3292: Rv3292 - Conserved hypothetical protein, at 3,672,328 to 3,673,575 Rv3292 Rv3293: Rv3293 - Probable piperideine-6-carboxilic acid dehydrogenase Pcd (piperideine-6-carboxylate dehydrogenase), at 3,673,602 to 3,675,086 Rv3293 Position (kb) 3672 3673 3674Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3671.499 kb on + strand, within Rv3290cat 3671.587 kb on + strand, within Rv3290cat 3671.587 kb on + strand, within Rv3290cat 3671.588 kb on - strand, within Rv3290cat 3671.588 kb on - strand, within Rv3290cat 3671.628 kb on + strand, within Rv3290cat 3671.643 kb on - strand, within Rv3290cat 3671.644 kb on + strand, within Rv3290cat 3671.645 kb on - strand, within Rv3290cat 3671.659 kb on - strand, within Rv3290cat 3671.659 kb on - strand, within Rv3290cat 3671.690 kb on + strandat 3671.690 kb on + strandat 3671.690 kb on + strandat 3671.690 kb on + strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.691 kb on - strandat 3671.758 kb on + strandat 3671.981 kb on + strand, within Rv3291cat 3671.981 kb on + strand, within Rv3291cat 3671.982 kb on - strand, within Rv3291cat 3672.028 kb on - strand, within Rv3291cat 3672.028 kb on - strand, within Rv3291cat 3672.137 kb on + strand, within Rv3291cat 3672.397 kb on + strandat 3672.397 kb on + strandat 3672.398 kb on - strandat 3672.398 kb on - strandat 3672.438 kb on - strandat 3672.756 kb on - strand, within Rv3292at 3672.969 kb on + strand, within Rv3292at 3673.026 kb on - strand, within Rv3292at 3673.261 kb on + strand, within Rv3292at 3673.261 kb on + strand, within Rv3292at 3673.355 kb on - strand, within Rv3292at 3673.355 kb on - strand, within Rv3292at 3673.355 kb on - strand, within Rv3292at 3673.355 kb on - strand, within Rv3292at 3673.357 kb on + strand, within Rv3292at 3673.357 kb on + strand, within Rv3292at 3673.357 kb on + strand, within Rv3292at 3673.543 kb on + strandat 3673.543 kb on + strandat 3673.543 kb on + strandat 3673.591 kb on + strandat 3673.631 kb on - strandat 3673.766 kb on + strand, within Rv3293at 3673.766 kb on + strand, within Rv3293at 3673.767 kb on - strand, within Rv3293at 3673.877 kb on - strand, within Rv3293at 3673.877 kb on - strand, within Rv3293

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamine (C)
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3,671,499 + Rv3290c 0.78 -0.5
3,671,587 + Rv3290c 0.85 -0.3
3,671,587 + Rv3290c 0.85 -0.2
3,671,588 - Rv3290c 0.85 -0.4
3,671,588 - Rv3290c 0.85 -0.4
3,671,628 + Rv3290c 0.88 -0.7
3,671,643 - Rv3290c 0.89 +0.5
3,671,644 + Rv3290c 0.89 -1.5
3,671,645 - Rv3290c 0.89 -0.3
3,671,659 - Rv3290c 0.90 +0.0
3,671,659 - Rv3290c 0.90 -0.6
3,671,690 + -0.4
3,671,690 + -0.4
3,671,690 + -0.5
3,671,690 + -0.8
3,671,691 - -0.4
3,671,691 - -0.4
3,671,691 - -1.4
3,671,691 - -0.2
3,671,691 - -0.5
3,671,691 - -0.6
3,671,758 + -0.3
3,671,981 + Rv3291c 0.30 -0.4
3,671,981 + Rv3291c 0.30 -0.1
3,671,982 - Rv3291c 0.30 -1.2
3,672,028 - Rv3291c 0.40 -0.7
3,672,028 - Rv3291c 0.40 +0.7
3,672,137 + Rv3291c 0.64 -0.2
3,672,397 + +0.1
3,672,397 + +0.7
3,672,398 - -0.4
3,672,398 - +0.3
3,672,438 - -0.7
3,672,756 - Rv3292 0.34 +0.7
3,672,969 + Rv3292 0.51 -0.1
3,673,026 - Rv3292 0.56 -0.3
3,673,261 + Rv3292 0.75 -2.7
3,673,261 + Rv3292 0.75 -0.6
3,673,355 - Rv3292 0.82 -0.5
3,673,355 - Rv3292 0.82 -0.2
3,673,355 - Rv3292 0.82 +1.7
3,673,355 - Rv3292 0.82 +0.3
3,673,357 + Rv3292 0.82 +0.0
3,673,357 + Rv3292 0.82 +0.1
3,673,357 + Rv3292 0.82 +0.7
3,673,543 + +0.0
3,673,543 + -0.2
3,673,543 + -0.7
3,673,591 + +0.1
3,673,631 - +0.1
3,673,766 + Rv3293 0.11 -0.3
3,673,766 + Rv3293 0.11 -0.0
3,673,767 - Rv3293 0.11 +2.8
3,673,877 - Rv3293 0.19 -0.2
3,673,877 - Rv3293 0.19 +0.4

Or see this region's nucleotide sequence