Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0734

Experiment: L-Glutamine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0732 and Rv0733 overlap by 4 nucleotidesRv0733 and Rv0734 are separated by 2 nucleotidesRv0734 and Rv0735 are separated by 72 nucleotidesRv0735 and Rv0736 are separated by 63 nucleotides Rv0732: Rv0732 - Probable preprotein translocase SecY, at 824,800 to 826,125 Rv0732 Rv0733: Rv0733 - Adenylate kinase Adk (ATP-AMP transphosphorylase), at 826,122 to 826,667 Rv0733 Rv0734: Rv0734 - Methionine aminopeptidase MapA (map) (peptidase M) (MetAP), at 826,670 to 827,470 Rv0734 Rv0735: Rv0735 - Probable alternative RNA polymerase sigma factor SigL, at 827,543 to 828,076 Rv0735 Rv0736: Rv0736 - Anti-sigma factor RslA, at 828,140 to 828,892 Rv0736 Position (kb) 826 827 828Strain fitness (log2 ratio) -1 0 1at 826.665 kb on + strandat 826.978 kb on - strand, within Rv0734at 827.248 kb on + strand, within Rv0734at 827.249 kb on - strand, within Rv0734at 827.468 kb on + strandat 827.598 kb on - strand, within Rv0735at 827.628 kb on - strand, within Rv0735at 827.923 kb on + strand, within Rv0735at 827.924 kb on - strand, within Rv0735at 827.946 kb on - strand, within Rv0735at 827.948 kb on + strand, within Rv0735at 828.023 kb on + strandat 828.024 kb on - strandat 828.067 kb on + strandat 828.112 kb on + strandat 828.112 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamine (C)
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826,665 + -0.8
826,978 - Rv0734 0.38 -0.5
827,248 + Rv0734 0.72 -0.9
827,249 - Rv0734 0.72 -0.6
827,468 + -0.3
827,598 - Rv0735 0.10 -0.0
827,628 - Rv0735 0.16 -0.4
827,923 + Rv0735 0.71 -0.2
827,924 - Rv0735 0.71 -0.2
827,946 - Rv0735 0.75 -0.6
827,948 + Rv0735 0.76 +0.8
828,023 + +0.5
828,024 - -0.4
828,067 + -0.5
828,112 + -0.8
828,112 + -0.2

Or see this region's nucleotide sequence