Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0248c

Experiment: L-Glutamine (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0246 and Rv0247c overlap by 4 nucleotidesRv0247c and Rv0248c are separated by 0 nucleotidesRv0248c and Rv0249c are separated by 30 nucleotidesRv0249c and Rv0250c are separated by 79 nucleotides Rv0246: Rv0246 - Probable conserved integral membrane protein, at 296,809 to 298,119 Rv0246 Rv0247c: Rv0247c - Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase), at 298,116 to 298,862 Rv0247c Rv0248c: Rv0248c - Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase), at 298,863 to 300,803 Rv0248c Rv0249c: Rv0249c - Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase), at 300,834 to 301,655 Rv0249c Rv0250c: Rv0250c - Conserved protein, at 301,735 to 302,028 Rv0250c Position (kb) 298 299 300 301Strain fitness (log2 ratio) -2 -1 0 1at 298.105 kb on - strandat 298.146 kb on + strandat 298.253 kb on + strand, within Rv0247cat 299.230 kb on - strand, within Rv0248cat 299.240 kb on - strand, within Rv0248cat 299.327 kb on - strand, within Rv0248cat 299.327 kb on - strand, within Rv0248cat 299.464 kb on - strand, within Rv0248cat 299.467 kb on + strand, within Rv0248cat 299.638 kb on + strand, within Rv0248cat 299.883 kb on - strand, within Rv0248cat 300.320 kb on - strand, within Rv0248cat 300.494 kb on - strand, within Rv0248cat 300.549 kb on - strand, within Rv0248cat 300.804 kb on - strandat 300.886 kb on + strandat 301.052 kb on - strand, within Rv0249cat 301.186 kb on + strand, within Rv0249cat 301.234 kb on + strand, within Rv0249cat 301.291 kb on + strand, within Rv0249cat 301.347 kb on + strand, within Rv0249cat 301.460 kb on - strand, within Rv0249cat 301.513 kb on + strand, within Rv0249cat 301.513 kb on + strand, within Rv0249cat 301.658 kb on - strandat 301.679 kb on + strandat 301.680 kb on - strandat 301.694 kb on + strandat 301.694 kb on + strandat 301.794 kb on - strand, within Rv0250c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Glutamine (C)
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298,105 - -0.9
298,146 + +0.9
298,253 + Rv0247c 0.18 -1.5
299,230 - Rv0248c 0.19 +0.9
299,240 - Rv0248c 0.19 +0.1
299,327 - Rv0248c 0.24 -1.7
299,327 - Rv0248c 0.24 -1.5
299,464 - Rv0248c 0.31 -1.0
299,467 + Rv0248c 0.31 -1.0
299,638 + Rv0248c 0.40 -2.0
299,883 - Rv0248c 0.53 -0.8
300,320 - Rv0248c 0.75 -1.7
300,494 - Rv0248c 0.84 -1.9
300,549 - Rv0248c 0.87 +0.6
300,804 - -0.5
300,886 + -2.1
301,052 - Rv0249c 0.27 -0.6
301,186 + Rv0249c 0.43 -1.0
301,234 + Rv0249c 0.49 +0.3
301,291 + Rv0249c 0.56 -0.4
301,347 + Rv0249c 0.62 -0.7
301,460 - Rv0249c 0.76 -1.3
301,513 + Rv0249c 0.83 -1.0
301,513 + Rv0249c 0.83 +0.6
301,658 - -1.7
301,679 + -1.4
301,680 - +0.1
301,694 + -0.9
301,694 + -1.3
301,794 - Rv0250c 0.20 +0.8

Or see this region's nucleotide sequence