Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3270

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3268 and Rv3269 are separated by 124 nucleotidesRv3269 and Rv3270 are separated by 10 nucleotidesRv3270 and Rv3271c overlap by 4 nucleotidesRv3271c and Rv3272 are separated by 100 nucleotides Rv3268: Rv3268 - Conserved hypothetical protein, at 3,649,420 to 3,650,109 Rv3268 Rv3269: Rv3269 - Conserved protein, at 3,650,234 to 3,650,515 Rv3269 Rv3270: Rv3270 - Probable metal cation-transporting P-type ATPase C CtpC, at 3,650,526 to 3,652,682 Rv3270 Rv3271c: Rv3271c - Probable conserved integral membrane protein, at 3,652,679 to 3,653,347 Rv3271c Rv3272: Rv3272 - Conserved hypothetical protein, at 3,653,448 to 3,654,632 Rv3272 Position (kb) 3650 3651 3652 3653Strain fitness (log2 ratio) -1 0 1at 3649.583 kb on + strand, within Rv3268at 3649.649 kb on + strand, within Rv3268at 3649.810 kb on + strand, within Rv3268at 3649.829 kb on + strand, within Rv3268at 3649.844 kb on + strand, within Rv3268at 3649.844 kb on + strand, within Rv3268at 3649.845 kb on - strand, within Rv3268at 3649.882 kb on - strand, within Rv3268at 3650.147 kb on + strandat 3650.167 kb on + strandat 3650.241 kb on + strandat 3651.459 kb on - strand, within Rv3270at 3651.807 kb on - strand, within Rv3270at 3652.517 kb on - strandat 3652.530 kb on + strandat 3653.640 kb on + strand, within Rv3272

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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3,649,583 + Rv3268 0.24 -0.1
3,649,649 + Rv3268 0.33 -0.7
3,649,810 + Rv3268 0.57 -0.5
3,649,829 + Rv3268 0.59 +0.2
3,649,844 + Rv3268 0.61 -0.2
3,649,844 + Rv3268 0.61 -0.4
3,649,845 - Rv3268 0.62 -0.6
3,649,882 - Rv3268 0.67 -0.1
3,650,147 + +0.0
3,650,167 + -0.0
3,650,241 + -0.5
3,651,459 - Rv3270 0.43 -1.3
3,651,807 - Rv3270 0.59 -0.3
3,652,517 - -1.0
3,652,530 + +1.0
3,653,640 + Rv3272 0.16 -0.5

Or see this region's nucleotide sequence