Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2847c

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2846c and Rv2847c are separated by 22 nucleotidesRv2847c and Rv2848c are separated by 276 nucleotides Rv2846c: Rv2846c - Possible integral membrane efflux protein EfpA, at 3,153,039 to 3,154,631 Rv2846c Rv2847c: Rv2847c - Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase, at 3,154,654 to 3,155,871 Rv2847c Rv2848c: Rv2848c - Probable cobyrinic acid A,C-diamide synthase CobB, at 3,156,148 to 3,157,521 Rv2848c Position (kb) 3154 3155 3156Strain fitness (log2 ratio) -1 0 1at 3154.645 kb on - strandat 3155.882 kb on + strandat 3155.882 kb on + strandat 3155.883 kb on - strandat 3156.106 kb on + strandat 3156.107 kb on - strandat 3156.162 kb on + strandat 3156.163 kb on - strandat 3156.222 kb on + strandat 3156.223 kb on - strandat 3156.637 kb on - strand, within Rv2848c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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3,154,645 - -0.4
3,155,882 + +0.2
3,155,882 + +0.1
3,155,883 - +0.7
3,156,106 + -0.3
3,156,107 - -1.6
3,156,162 + -0.3
3,156,163 - -1.0
3,156,222 + -0.1
3,156,223 - -0.0
3,156,637 - Rv2848c 0.36 -0.4

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