Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3910

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3909 and Rv3910 overlap by 4 nucleotidesRv3910 and Rv3911 are separated by 34 nucleotidesRv3911 and Rv3912 are separated by 15 nucleotides Rv3909: Rv3909 - Conserved protein, at 4,394,192 to 4,396,600 Rv3909 Rv3910: Rv3910 - Probable conserved transmembrane protein, at 4,396,597 to 4,400,151 Rv3910 Rv3911: Rv3911 - Possible alternative RNA polymerase sigma factor SigM, at 4,400,186 to 4,400,854 Rv3911 Rv3912: Rv3912 - Hypothetical alanine rich protein, at 4,400,870 to 4,401,634 Rv3912 Position (kb) 4396 4397 4398 4399 4400 4401Strain fitness (log2 ratio) -2 -1 0 1at 4398.331 kb on + strand, within Rv3910at 4398.752 kb on + strand, within Rv3910at 4398.752 kb on + strand, within Rv3910at 4399.819 kb on + strandat 4399.820 kb on - strandat 4399.843 kb on - strandat 4400.082 kb on + strandat 4400.082 kb on + strandat 4400.185 kb on + strandat 4400.204 kb on + strandat 4400.325 kb on + strand, within Rv3911at 4400.326 kb on - strand, within Rv3911at 4400.326 kb on - strand, within Rv3911at 4400.326 kb on - strand, within Rv3911at 4400.520 kb on + strand, within Rv3911at 4400.520 kb on + strand, within Rv3911at 4400.798 kb on - strandat 4400.798 kb on - strandat 4401.135 kb on + strand, within Rv3912at 4401.136 kb on - strand, within Rv3912at 4401.136 kb on - strand, within Rv3912

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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4,398,331 + Rv3910 0.49 -0.6
4,398,752 + Rv3910 0.61 -0.7
4,398,752 + Rv3910 0.61 -0.2
4,399,819 + -0.7
4,399,820 - +1.1
4,399,843 - -1.5
4,400,082 + -0.8
4,400,082 + +0.0
4,400,185 + -0.3
4,400,204 + -0.3
4,400,325 + Rv3911 0.21 -0.0
4,400,326 - Rv3911 0.21 -0.3
4,400,326 - Rv3911 0.21 -0.3
4,400,326 - Rv3911 0.21 -0.7
4,400,520 + Rv3911 0.50 -0.4
4,400,520 + Rv3911 0.50 -0.4
4,400,798 - -1.2
4,400,798 - -0.8
4,401,135 + Rv3912 0.35 -0.8
4,401,136 - Rv3912 0.35 +0.3
4,401,136 - Rv3912 0.35 -1.8

Or see this region's nucleotide sequence