Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3748

Experiment: L-Aspartic Acid (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3746c and Rv3747 are separated by 217 nucleotidesRv3747 and Rv3748 are separated by 128 nucleotidesRv3748 and Rv3749c are separated by 32 nucleotidesRv3749c and Rv3750c are separated by 67 nucleotides Rv3746c: Rv3746c - Probable PE family protein PE34 (PE family-related protein), at 4,196,171 to 4,196,506 Rv3746c Rv3747: Rv3747 - Conserved protein, at 4,196,724 to 4,197,107 Rv3747 Rv3748: Rv3748 - Conserved hypothetical protein, at 4,197,236 to 4,197,595 Rv3748 Rv3749c: Rv3749c - Conserved hypothetical protein, at 4,197,628 to 4,198,137 Rv3749c Rv3750c: Rv3750c - Possible excisionase, at 4,198,205 to 4,198,597 Rv3750c Position (kb) 4197 4198Strain fitness (log2 ratio) -2 -1 0 1 2at 4196.433 kb on - strand, within Rv3746cat 4196.518 kb on + strandat 4196.518 kb on + strandat 4196.518 kb on + strandat 4196.628 kb on + strandat 4196.628 kb on + strandat 4196.629 kb on - strandat 4196.629 kb on - strandat 4196.646 kb on - strandat 4196.678 kb on + strandat 4196.678 kb on + strandat 4196.728 kb on + strandat 4196.729 kb on - strandat 4196.732 kb on + strandat 4196.891 kb on + strand, within Rv3747at 4196.891 kb on + strand, within Rv3747at 4196.891 kb on + strand, within Rv3747at 4196.892 kb on - strand, within Rv3747at 4197.097 kb on + strandat 4197.175 kb on + strandat 4197.176 kb on - strandat 4197.241 kb on - strandat 4197.510 kb on + strand, within Rv3748at 4197.600 kb on + strandat 4197.600 kb on + strandat 4197.601 kb on - strandat 4197.601 kb on - strandat 4197.601 kb on - strandat 4197.630 kb on - strandat 4197.630 kb on - strandat 4197.630 kb on - strandat 4197.734 kb on - strand, within Rv3749cat 4197.734 kb on - strand, within Rv3749cat 4197.734 kb on - strand, within Rv3749cat 4197.767 kb on + strand, within Rv3749cat 4197.798 kb on + strand, within Rv3749cat 4197.866 kb on + strand, within Rv3749cat 4197.867 kb on - strand, within Rv3749cat 4197.867 kb on - strand, within Rv3749cat 4197.875 kb on - strand, within Rv3749cat 4197.913 kb on + strand, within Rv3749cat 4197.913 kb on + strand, within Rv3749cat 4197.947 kb on - strand, within Rv3749cat 4197.965 kb on + strand, within Rv3749cat 4197.965 kb on + strand, within Rv3749cat 4197.965 kb on + strand, within Rv3749cat 4197.965 kb on + strand, within Rv3749cat 4197.965 kb on + strand, within Rv3749cat 4197.966 kb on - strand, within Rv3749cat 4197.966 kb on - strand, within Rv3749cat 4197.966 kb on - strand, within Rv3749cat 4198.104 kb on + strandat 4198.104 kb on + strandat 4198.105 kb on - strandat 4198.179 kb on - strandat 4198.179 kb on - strandat 4198.207 kb on - strandat 4198.266 kb on - strand, within Rv3750cat 4198.433 kb on + strand, within Rv3750cat 4198.497 kb on + strand, within Rv3750cat 4198.497 kb on + strand, within Rv3750cat 4198.498 kb on - strand, within Rv3750cat 4198.498 kb on - strand, within Rv3750c

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Per-strain Table

Position Strand Gene LocusTag Fraction L-Aspartic Acid (C)
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4,196,433 - Rv3746c 0.78 -0.1
4,196,518 + -0.3
4,196,518 + +0.7
4,196,518 + +2.3
4,196,628 + +0.1
4,196,628 + +0.5
4,196,629 - +1.4
4,196,629 - +0.7
4,196,646 - +0.5
4,196,678 + +0.5
4,196,678 + +0.5
4,196,728 + -0.2
4,196,729 - -0.0
4,196,732 + -0.6
4,196,891 + Rv3747 0.43 +0.6
4,196,891 + Rv3747 0.43 -1.4
4,196,891 + Rv3747 0.43 -0.7
4,196,892 - Rv3747 0.44 -0.0
4,197,097 + +1.7
4,197,175 + +1.7
4,197,176 - +0.5
4,197,241 - -1.8
4,197,510 + Rv3748 0.76 -0.9
4,197,600 + -0.5
4,197,600 + +0.3
4,197,601 - +0.7
4,197,601 - +0.3
4,197,601 - -0.1
4,197,630 - -0.3
4,197,630 - -0.5
4,197,630 - -0.2
4,197,734 - Rv3749c 0.21 +0.1
4,197,734 - Rv3749c 0.21 +0.0
4,197,734 - Rv3749c 0.21 -0.0
4,197,767 + Rv3749c 0.27 -0.6
4,197,798 + Rv3749c 0.33 -0.1
4,197,866 + Rv3749c 0.47 -0.4
4,197,867 - Rv3749c 0.47 -0.2
4,197,867 - Rv3749c 0.47 -0.4
4,197,875 - Rv3749c 0.48 +0.2
4,197,913 + Rv3749c 0.56 +0.3
4,197,913 + Rv3749c 0.56 -0.6
4,197,947 - Rv3749c 0.63 -0.9
4,197,965 + Rv3749c 0.66 -0.3
4,197,965 + Rv3749c 0.66 -0.3
4,197,965 + Rv3749c 0.66 -0.2
4,197,965 + Rv3749c 0.66 +0.0
4,197,965 + Rv3749c 0.66 -0.2
4,197,966 - Rv3749c 0.66 +0.1
4,197,966 - Rv3749c 0.66 -0.7
4,197,966 - Rv3749c 0.66 +0.3
4,198,104 + +0.2
4,198,104 + -0.0
4,198,105 - -0.3
4,198,179 - -1.4
4,198,179 - -0.4
4,198,207 - -0.1
4,198,266 - Rv3750c 0.16 -0.1
4,198,433 + Rv3750c 0.58 -0.2
4,198,497 + Rv3750c 0.74 +2.7
4,198,497 + Rv3750c 0.74 -0.3
4,198,498 - Rv3750c 0.75 +0.7
4,198,498 - Rv3750c 0.75 -0.4

Or see this region's nucleotide sequence